... studies, SD is commonly considered a disease of the central nervoussystem (CNS) and elucidation of the peripheralnervoussystem (PNS) in patients and animal models remains incomplete To illuminate ... concentrations (mg per 100 mg dry weight) Abbreviations SD = Sandhoff disease PNS = peripheralnervoussystem CNS = central nervoussystem GSL = glycosphingolipid XRD = low-angle x-ray diffraction CNCV ... be used as a marker for the amount of myelin in the PNS tissue if the ganglioside distribution in mouse PNS tissue is similar to that in rat PNS tissue [25] In the are expressed as mean ± SEM...
... mechanisms are conserved in the development of various biological systems, from the nervous system, vascular system and immune system, how a single molecule is able to control extremely precise ... Neuropilin: From NervousSystem to Vascular and Tumor Biology Neuropilin: From NervousSystem to Vascular and Tumor Biology Edited by Dominique Bagnard, ... growth factor PlGF-2: Heparin binding form of PlGF PlGF-2: Placenta growth factor-2 PNS: Peripheralnervoussystem Contents xvi p-Sp: Para-aortic splanchnopleural mesoderm ROP: Retinopathy of...
... somatic nervoussystem developed in addition to the autonomic nervous system; it consists of the central nervoussystem (CNS; brain and spinal cord), and the peripheralnervoussystem (PNS; the ... vegetative) nervoussystem (ANS), and consists of two components which often have opposing functions: the sympathetic nervoussystem and the parasympathetic nervoussystem The interaction of these two systems ... information (integration) Note that most textbooks include the peripheral nerves of the autonomic nervoussystem in the PNS The nervous system, the remaining organism, and the environment are functionally...
... 81.2 76.7 69.5 63.7 60.6 Other Central NervousSystem National Cancer Institute 205 SEER Survival Monograph Chapter 25 Cancer of the Brain and NervousSystem Table 25.3: Cancer of the Brain: ... Specified 210 SEER Survival Monograph Chapter 25 Cancer of the Brain and NervousSystem Table 25.7: Cancer of the Other Central Nervous System: Distributions and 5-Year Relative Survival Rates (%) by ... Institute 211 SEER Survival Monograph Chapter 25 Cancer of the Brain and NervousSystem Table 25.9: Cancer of the Other Central NervousSystem Cancer: 1-, 2-, 3-, 5-, 8-, & 10-Year Relative Survival Rates...
... (coral, jellyfish, sea anemones), which possess the most primitive form of nervous system, suggesting that the archetype nervous systems may have relied on amidated peptides [5] The C-terminal a-amidation ... b561 gene product was specifically expressed in the planarian nervoussystem [40], suggesting that the AsA-related electron transfer system, which supports amidation of the neuropeptide, might ... b561: conservation of a six-transmembrane structure and localization along the central and peripheralnervoussystem J Biochem 131, 175–182 41 Prigge ST, Kolhekar AS, Eipper BA, Mains RE & Amzel LM...
... nervoussystem CENTRAL NERVOUSSYSTEM Brain and spinal cord (CNS) consists of the brain and spinal cord The brain sends nerve signals to specific parts of Cervical region PERIPHERALNERVOUSSYSTEM ... understanding the brain, spinal cord and peripheralnervoussystem Neuroscientists investigate the molecular and cellular levels of the nervous system; the neuronal systems responsible for sensory and ... NERVOUSSYSTEM Nerves extending from spinal cord the body through peripheral nerves, known as the peripheralnervoussystem (PNS) Peripheral nerves in the cervical region Thoracic region serve the...
... inflammatory disease, characterized by the appearance of focal demyelinated plaques within the central nervoussystem (CNS) [1] Essential aspects of MS lesions are mimicked in models of experimental autoimmune ... (ABC) detection system (ABC Elite, Vector Laboratories) and diaminobenzidine as chromogen Finally, a biotinylated lectin (GSA/B4, Vector Laboratories) combined with the ABC detection system was used ... Sellebjerg F, Lassmann H, Ransohoff RM: CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervoussystem of patients with multiple sclerosis Am J Pathol 2001, 159:1701-10 Huitinga I, van Rooijen...
... central nervoussystem has received far more research attention than has the peripheralnervoussystem Nevertheless, age-related changes and diseases involving the peripheralnervous system, ... : alk paper) Autonomic nervoussystem Pathophysiology–Age factors Autonomic nervoussystem Aging I Kuchel, George A II Hof, Patrick R III Series [DNLM: Autonomic NervousSystem physiology–Aged ... the central and peripheralnervoussystem of man and experimental animals [94] Mechanisms relevant to the pathogenesis of NAD in the relatively simple aging peripheralnervoussystem may be extrapolated...
... the autonomic nervous system, and they may integrate somatic and vegetative functions, including those of the cardiovascular and gastrointestinal systems Limbic System The "limbic system" is an ... outlines and details already described for the peripheral autonomic nervoussystem (seeChapter 6: Neurotransmission: The Autonomic and Somatic Motor Nervous Systems) However, in the CNS there is found ... of the so-called extrapyramidal motor system This system complements the function of the pyramidal (or voluntary) motor system Damage to the extrapyramidal system depresses the ability to initiate...
... doses of chemotherapy, necessitating either bone marrow transplantation or peripheral stem cell support to boost the immune system, and either no craniospinal radiation or focused radiation to the ... asymptomatic children with acute lymphocytic leukemia after prophylactic treatment of the central nervoussystem with radiation and intrathecal chemotherapy N Engl J Med 1978, 298:815-818 Duffner PK, ... doses has become routine Very high dose chemotherapy, requiring bone marrow transplantation or peripheral stem cell support, is now standard therapy for children with certain brain tumors, especially...
... most other organ systems compromised by cancer treatments One of the tissues for which adverse side effects of cancer treatment are clinically important is the central nervoussystem (CNS) Although ... normal cell types, leading to a broad range of adverse side effects in multiple organ systems In the hematopoietic system, the tissue in which such adverse effects have been most extensively studied, ... AK, Correa DD, Yahalom J, DeAngelis LM, Abrey LE: Delayed neurotoxicity in primary central nervoussystem lymphoma Arch Neurol 2005, 62:1595-1600 Dropcho EJ: Neurotoxicity of cancer chemotherapy...
... Dietrich J, Luebke A, Mayer-Pröschel M, Noble M: Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervoussystem J Biol 2008, 7:12 Lee GD, Longo DL, ... other studies will guide the development of translational clinical research to protect the nervoussystem from injury, to better treat injury that has developed as a result of treatment, and ... Bivens S, Mitchell T, Greenberg ER, Silberfarb PM: e Neuropsychological impact of standard dose systemic chemother apy in long-term survivors of breast cancer and lymphoma J Clin Oncol 2002, 20:485-493...
... and B, ×66 C and D, ×132 Immunohistochmical study of nitric oxide synthase in the central nervoussystem of goat Enhanced expression of nNOS and iNOS in L monocytogenes-infected brain At necropsy, ... and Koprowski, H Local nitric oxide production in viral and autoimmune disease of the central nervoussystem Proc Natl Acad Sci U.S.A 1995, 92, 5312-5316 Johnson, G.C., Fales, W.H., Maddox, C.W ... study were from animals submitted for necropsy to the Pennsylvania Animal Diagnostic Laboratory System (PADLS) in Harrisburg, Pennsylvania In all the selected midbrains, L monocytogenes was confirmed...
... central nervoussystem vasculitis: analysis of 101 patients Ann Neurol 2007, 62:442-451 MacLaren K, Gillespie J, Shrestha S, Neary D, Ballardie FW: Primary angiitis of the central nervous system: ... of the Central Nervous System: a Case Report and Review CNS Spectrums 2008, 13:209-213 Page of 10 Ozawa T, Sasaki O, Sorimachi T, Tanaka R: Primary angiitis of the central nervous system: report ... central nervous system: initial and follow-up MR features Neuroradiology 2009, 51:651-659 12 Ay H, Sahin G, Saatci I, Söylemezoğlu F, Saribaş O: Primary Angiitis of the Central Nervous System...
... central nervous system: an interpretation of target cell responses Br J Cancer 1986, 53(Suppl 7):207-217 Schultheiss TE, Kun LE, Ang KK, Stephens LC: Radiation response of the central nervoussystem ... stem cells and neural crest stem cells The latter give rise to neurons and glia of the peripheralnervoussystem and other connective cell types The subventricular zones (SVZ) adjacent to the ... http://www.ro-journal.com/content/2/1/23 Table 1: Overview of experimental studies of central nervoussystem (CNS) radioprotection Reference Animals CNS region RT schedule AF schedule Follow-up...
... studies on neuronal degeneration in dt/dt mice focused on the sensory nerve system [3,5], whereas the autonomic nervoussystem was seldom addressed In our previous study of spinal motor neurons ... development, but neuronal degeneration is limited to peripheral neurons derived from neural crest cells in BPAG1-deficient mice The autonomic system is considered unaffected by neurodegenerative ... deficiency in BPAG1, the cytoskeletal linker protein, may induce neuronal death in the sympathetic nervoussystem of dt/dt mice during development Tseng et al Journal of Biomedical Science 2011, 18:9...
... central nervoussystem Archives of neurology 2008, 65(1):65-70 Hagberg L, Dotevall L, Norkrans G, Larsson M, Wachter H, Fuchs D: Cerebrospinal fluid neopterin concentrations in central nervoussystem ... phagocytes J Acquir Immune Defic Syndr 2002, 31(Suppl 2):S43-54 Williams KC, Hickey WF: Central nervoussystem damage, monocytes and macrophages, and neurological disorders in AIDS Annu Rev Neurosci ... Eden A, Price RW, Spudich S, Fuchs D, Hagberg L, Gisslen M: Immune activation of the central nervoussystem is still present after >4 years of effective highly active antiretroviral therapy The...
... effects of central nervoussystem prophylactic treatment in childhood leukemia: methodological considerations J Pediatr Psychol 1993, 18(3):319-338 Kaleita TA: Central nervous system- directed therapy ... patients into the study List of Abbreviations ALL: Acute lymphoblastic leukaemia; CNS: Central nervous system; IQ: Intelligence Quotient; MTX: methotrexate; WCC: white cell count; IT: intrathecal; ... et al: Minimal neuropsychological sequelae following prophylactic treatment of the central nervoussystem in adult leukaemia and lymphoma Br J Cancer 1989, 60(5):775-780 Sowell ER, Thompson PM,...