peptides antibodies and regents
Báo cáo y học: "Relationship between Anti-CCP Antibodies and Oxidant and Anti-Oxidant Activity in Patients with Rheumatoid Arthrit"
... the mean whole blood and serum antioxidative activity (CAT, GSHpx) and the mean blood and serum MDA and MPO values (oxidative activity), between the patients with anti-CCP(+) and those with anti-CCP(-) ... *p
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Báo cáo khoa học: Multifunctional host defense peptides: functional and mechanistic insights from NMR structures of potent antimicrobial peptides docx
... peptides and designed peptides in complex with LPS, using NMR experiments, to gain insights into the peptide interactions with LPS [52–57] LPS-bound structures of peptides and antimicrobial peptides ... b-strands and b-turn structures in LPS micelles [52,54,57] With a set of designed peptides, the LPS-bound structures reveal multiple b-turn and b-strand structures (Fig 4) of these antimicrobial and ... tachyplesins, and protegrins), and extended (e.g indolicidin and PR-39) [13–15] Although they are highly diverse in amino acid sequences and structures, a common feature shared among the antimicrobial peptides...
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peptides chemistry and biology
... separation and purification of peptides and proteins 2.3.1 Separation and Purification 2.3.1.1 Separation Principles Analysis and purification of naturally occurring peptides and of synthetic peptides ... b -Peptides, Hydrazino Peptides, Aminoxy Peptides, and Oligosulfonamides 361 339 IX X Contents 7.4.4 7.4.5 7.5 7.5.1 7.5.2 7.5.3 7.6 Oligocarbamates 362 Oligopyrrolinones 363 Macropeptides and ... Cystine Peptides 320 Glycopeptides 322 Phosphopeptides 329 Lipopeptides 331 Sulfated Peptides 333 References 334 7.1 7.2 7.2.1 7.2.2 7.2.3 7.2.4 7.2.5 7.3 7.4 7.4.1 7.4.2 7.4.3 Peptide and Protein...
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Báo cáo y học: "Anti-SSA/Ro antibodies and the heart: more than complete congenital heart block? A review of electrocardiographic and myocardial abnormalities and of treatment options" ppt
... of the fetal heart between 16 and 30 weeks of gestation, and anti-SSA/Ro antibodies were not considered pathogenic for the adult heart In support of this, Gordon and colleagues [20] did not find ... anti-SSA/Ro antibodies is undoubtedly expanding In addition to the classical complete and incomplete CHB, there is progressive recognition of transient CHB, severe late-onset cardiomyopathy and endocardial ... disease and pregnancy: report of six cases Eur J Obstet Gynecol Reprod Biol 1996, 64:143146 34 Buyon JP, Clancy RM: Maternal autoantibodies and congenital heart block: mediators, markers, and therapeutic...
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Báo cáo y học: "Anti-Sa antibodies and antibodies against cyclic citrullinated peptide are not equivalent as predictors of severe outcomes in patients with recent-onset polyarthritis" pdf
... manufacturer's recommendations) Standardized radiographs of the hands and feet were obtained at inclusion and at each scheduled assessment Joint space narrowing and erosions were scored by the ... coordinating nurses and treating physicians remained blinded to the patients' HLA-DR, anti-CCP and anti-Sa status Serum and DNA materials were coded to ensure confidentiality and blinding of investigators ... of clinical experience and confirmed by its optimal prognostic value), genomic typing of the HLA-DR (see below), measure of anti-Sa antibodies (see below) and anti-CCP antibodies (QuantaLite™;...
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Báo cáo y học: "Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity" docx
... Immunohistopathology and serum levels of anti-type II collagen autoantibodies Scand J Immunol 1990, 31:147-157 16 Nandakumar KS, Backlund J, Vestberg M, Holmdahl R: Collagen type II (CII)-specific antibodies ... each individual and day in accordance with the following relation between extended and simple: = 1, to 10 = 2, and 11 to 15 = Statistics All ELISA data were first log-transformed and then used ... and littermate controls were randomly and pooled blind dAnti-CII antibody-induced arthritis on pure line of male C9T-BQ (homozygous Ab) and male B10.Q (wild-type Ab), and controls injected with...
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Báo cáo y học: " Independent associations of anti-cyclic citrullinated peptide antibodies and rheumatoid factor with radiographic severity of rheumatoid arthritis" potx
... between radiographic outcome in longstanding disease (as assessed by modified Larsen's score) and RF, anti-CCP and SE alleles We report independent associations of RF and anti-CCP with radiographic ... MHB and AGW designed the study AC, DJM, IM and JK acquired the data DM performed data analysis and all of the authors were involved in the interpretation of the data All of the authors read and ... subgroups stratified for both anti-CCP and RF status we found evidence of independent associations of both RF and anti-CCP with radiographic outcome Those with both RF and anti-CCP expressed the most...
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Báo cáo y học: "Anticitrullinated protein/peptide antibodies and rheumatoid factors: two distinct autoantibody systems" ppsx
... Arthritis Research & Therapy Vol 11 No Valesini and Alessandri clinical phase of RA [10], but ACPA positivity is likely to develop earlier and its presence may contribute to the subsequent ... antibody and rheumatoid factor for rheumatoid arthritis Ann Intern Med 2007, 146:797-808 Avouac J, Gossec L, Dougados M: Diagnostic and predictive value of anti cyclic citrullinated protein antibodies ... phenotypes and biomarkers: a case study of rheumatoid arthritis Bioinformatics 2006, 22: 1503-1507 Chibnik LB, Mandl LA, Costenbader KH, Schur PH, Karlson EW: Comparison of threshold cut-points and...
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Báo cáo y học: "Relationship between anti-dsDNA, anti-nucleosome and anti-alpha-actinin antibodies and markers of renal disease in patients with lupus nephritis: a prospective longitudinal study" pdf
... (dsDNA), (b) nucleosomes and α-actinin and (c) dsDNA and αCorrelation between binding to (a) nucleosomes and double-stranded DNA (dsDNA), (b) nucleosomes and α-actinin and (c) dsDNA and αactinin Absorbance ... anti-nucleosome and anti-α-actinin antibodies, levels of highavidity anti-dsDNA antibodies and markers of renal disease, including an assessment of whether the patients entered renal remission Materials and ... study and to obtain samples, to carry out immunoassays and statistical analyses, to conceive and design the study and to write the final manuscript DPD helped to recruit patients for the study and...
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Báo cáo y học: "Levels of anti-citrullinated protein antibodies and IgM rheumatoid factor are not associated with outcome in early arthritis patients: a cohort study" ppt
... one year of follow up ACPA and IgM-RF levels were modestly correlated with SHS (r = 0.12 and r = 0.11, respectively, both P = 0.01) and not with DAS28 and HAQ (Tables and 2) Patients positive for ... http://arthritis-research.com/content/12/1/R8 Page of Autoantibodies: change in status and levels between baseline and one year Baseline autoantibody levels and status, and outcome Outcome parameters at baseline After one year, ... committee and all patients gave written informed consent to be included in the study For the present analysis, all patients with available ACPA and IgM-RF data at baseline and after one year, and available...
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Báo cáo y học: "Immediate determination of ACPA and rheumatoid factor - a novel point of care test for detection of anti-MCV antibodies and rheumatoid factor using a lateral-flow immunoassay" pdf
... standardized anti-MCV and RF-ELISA (Orgentec, Mainz, Germany) The ratio of applied antigens and serum anti-MCV antibodies and/ or RF was such that monodentate binding of autoantibodies to the epitopes ... autoantibodies against citrullinated protein/peptide antigens; anti-MCV: autoantibodies against mutated and citrullinated vimentin; anti-CCP: autoantibodies against cyclic citrullinated peptides; ... acquisition, statistics, and created graphics and partially wrote the manuscript HB and GF developed the method and provided technical details EF contributed to data acquisition and partially wrote...
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Báo cáo toán học: " Improved labelling of DTPA- and DOTA-conjugated peptides and antibodies with In-111 in HEPES and MES buffer" ppt
... Improved labelling of DTPA- and DOTA-conjugated peptides and antibodies with 111In in HEPES and MES buffer Maarten Brom*1, Lieke Joosten1, Wim JG Oyen1, Martin Gotthardt1 and Otto C Boerman1 Department ... with SPECT Keywords: 111In-radiolabelling; peptides; antibodies; chelator Introduction Radiolabelled peptides and antibodies are used for molecular imaging and radionuclide therapy of tumours The ... 111InCl3, and the expiry date of 111InCl3 is 11 days after the production of 111InCl3) The peptides and antibodies were dissolved in metal-free water to a final concentration of 0.1 µg/µl, and µl...
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báo cáo hóa học:" Improved labelling of DTPA- and DOTA-conjugated peptides and antibodies with In-111 in HEPES and MES buffer" doc
... Improved labelling of DTPA- and DOTA-conjugated peptides and antibodies with 111In in HEPES and MES buffer Maarten Brom*1, Lieke Joosten1, Wim JG Oyen1, Martin Gotthardt1 and Otto C Boerman1 Department ... with SPECT Keywords: 111In-radiolabelling; peptides; antibodies; chelator Introduction Radiolabelled peptides and antibodies are used for molecular imaging and radionuclide therapy of tumours The ... 111InCl3, and the expiry date of 111InCl3 is 11 days after the production of 111InCl3) The peptides and antibodies were dissolved in metal-free water to a final concentration of 0.1 µg/µl, and µl...
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Báo cáo y học: " Environmental risk factors differ between rheumatoid arthritis with and without auto-antibodies against cyclic citrullinated peptides" potx
... Foundation, Henny and Helge Holgersens Memorial Fund, Torben and Alice Frimodt's Foundation, Max Fodgaard's Foundation, Niels Hansen and Wife's Foundation, and Frode V Nyegaard and Wife's Foundation ... collection, and drafting of the manuscript and performed statistical analyses SJ and MF participated in the study design and drafting of the manuscript MK participated in the data collection and drafting ... education Viral antibodies in serum and self-reported health conditions Seropositivity for parvovirus B19 antibodies (OR = 1.11; 95% CI: 0.81 to 1.52, 358 patients versus 409 controls) and above-median...
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Báo cáo y học: " Presence and utility of IgA-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis: the Swedish TIRA project" docx
... nated peptides IgA-class and IgG-class antibodies against cyclic citCorrelation of IgA-class and IgG-class antibodies against cyclic citrullirullinated peptides Correlation between IgG-class antibodies ... findings in hands and feet were comparable between anti-CCP-positive and anti-CCP-negative patients (14% versus 12%) for both IgA-class and IgG-class antibodies IgA anti-CCP status and IgG anti-CCP ... levels IgA-class antibodies against in IgG-positive patients with and without IgA-class antibodies against cyclic citrullinated peptides Box plots illustrating the median IgG-class antibodies against...
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Báo cáo y học: "Diagnostic and prognostic value of antibodies against chimeric fibrin/filaggrin citrullinated synthetic peptides in rheumatoid arthritis" doc
... and anti-CFFCP3 antibodies and those with and without anti-CCP2 antibodies The DAS28 score decreased significantly in positive and negative patients, but differences were not significant at and ... antibodies and other qualitative variables was tested by using the 2 test and Fisher's Exact test, as applicable Sensitivity, specificity, and positive and negative predictive values (PPVs and ... Anti-CFFCP antibodies in early RA Serum levels of the three anti-CFFCP antibodies and antiCCP2 antibodies were obtained at baseline in all 98 patients Positive anti-CFFCP1, anti-CFFCP2, and anti-CFFCP3...
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Báo cáo y học: "Long Term Persistence of IgE Anti-Influenza Virus Antibodies in Pediatric and Adult Serum Post Vaccination with Influenza Virus Vaccine"
... anti-influenza antibodies over time were not determined Given the findings of this study, the presence and persistence of IgG and IgE anti-influenza antibodies in the serum from those with normal and ele- ... conditions (50-64 y/o), and for children months and older [21, 25] In some countries, vaccination is recommended for health care workers, and caregivers in nursing homes and assisted living facilities ... vaccination, and then was two-fold lower moths post vaccination [31]; influenza specific IgG1 antibodies were the dominant antibody detected, as well as lower levels of IgM and IgA [31]; IgE antibodies...
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Tài liệu Báo cáo khoa học: Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity docx
... neutrophils, and eccrine glands [13] Cathelicidins kill Gram-positive and Gram-negative bacteria and Trypanosoma cruzi Similar to defensins, cathelicidins participate actively in linking innate and adaptive ... Gram-positive and Gram-negative bacteria and opportunistic yeasts such as Candida albicans [27] b-Defensin expression is modulated in response to bacterial-derived molecules and ⁄ or to cytokines and chemokines ... IL-1a, and IL-6 [36], and upon contact with Staphylococcus aureus [37] Cathelicidin peptides have potent, direct antimicrobial activity against Gram-positive and Gram-negative bacteria and, importantly,...
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Tài liệu Báo cáo khoa học: Analysis of proteins and peptides on a chromatographic timescale by electron-transfer dissociation MS ppt
... of peptides and proteins N D Udeshi et al dimethylation of Arg, monomethylation, dimethylation and trimethylation of Lys, acetylation and ubiquitination of Lys, and phosphorylation of Ser and ... fragment ions of type c¢ and z¢Æ are shown with right-angle arrows above and below the sequence, respectively Singly and multiply charged ions are indicated by solid and dashed lines, respectively ... modification is found on proteins in both the nucleus and cytoplasm, is added and removed by transferase and O-GlcNAcase enzymes, respectively, and often occurs at sites that are known to be phosphorylated...
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Tài liệu Báo cáo khoa học: Binding of N- and C-terminal anti-prion protein antibodies generates distinct phenotypes of cellular prion proteins (PrPC) obtained from human, sheep, cattle and mouse doc
... SAF34 and 8G8 for humans, SAF34, 8G8 and P4 for sheep, SAF34 and P4 for cattle, and SAF34 for mice; and for the C-terminal antibodies 6H4, SAF60 and SAF70 for humans, and mAbs 6H4, SAF60, SAF70 and ... N-terminal binding antibodies as SAF34 detected only full-length PrPC, C-terminal binding antibodies recognized two bands comprising full-length PrPC and an 18–19 kDa protein band corresponding ... with PrPC from cattle, sheep and mice High signal ratios were determined for di-glycosylated ovine PrPC with antibodies SAF34, 8G8 and P4 and lower intensities for mono- and nonglycosylated ovine...
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