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patterning stem cell in the third dimension

The search for stem cell in human breast milk

The search for stem cell in human breast milk

Thạc sĩ - Cao học

... systems with epithelial cells’ lining, studies have document the presence of the of the stem cell in the luminal discharges due to the proximity of the stem cell niche to their luminal cavities ... from a single cell and that this single cell can give rise to both luminal epithelial and myoepithelial cell types, suggesting the presence of a self-renewing pluripotent stem cell in the mouse ... earlier finding that proliferating cells are found in the luminal population as cell division and expression of antigens associated with proliferation being exceedingly rare in the myoepithelial cell...
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Trends in the European Investment Fund Industry in the Third Quarter of 2012 pot

Trends in the European Investment Fund Industry in the Third Quarter of 2012 pot

Quỹ đầu tư

... September 2012 Since end 2011, total net assets of non-UCITS have increased 10.6 percent The increase in non-UCITS assets during the third quarter was driven by a 4.5 percent increase in the net assets ... Trends in the UCITS Market Net Assets by Investment Type Long-term funds benefitted from sustained net inflows during the quarter in anticipation of ECB action to make progress against the euro ... net inflows into UCITS in the third quarter of 2012, with five countries attracting net inflows in excess of EUR billion: Luxembourg (EUR 24 billion), Ireland (EUR 19 billion), the United Kingdom...
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Aurelian or, Rome in the Third Century potx

Aurelian or, Rome in the Third Century potx

Khoa học xã hội

... seat on the southern declivity of the hill, overlooking the course of the Tiber as it winds away to the sea Mine is not far from it, but on the northern side of the hill, and thereby possessing a ... draw the world with them, to join them in their unhallowed orgies, thus stripping the temples of their worshippers, and dragging the gods themselves from their seats? Think you the gods look on ... to conform their religious doctrine and offerings to their feelings and instincts But the Romans, by nature and long training, lovers of blood, their country built upon the ruins of others, and...
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university of california press fundamentals of the stem cell debate the scientific religious ethical and political issues dec 2007

university of california press fundamentals of the stem cell debate the scientific religious ethical and political issues dec 2007

Cao đẳng - Đại học

... during division of a neural stem cell in a fly embryo, showing the opposite localizations for ACD determinants in the stem cell and differentiating cell The Miranda protein, stained red, marks the ... the same cells and in different cells (D) These cells, grown from the neural retina, show staining common to brain neural stem cells (DCX, red) and staining found only in neural stem cells derived ... 2001) The presence of neural stem cells in the adult brain accounts for the finding that neurons are generated constantly, even into adulthood, in many regions of the brain, including the SVZ of the...
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Báo cáo y học:

Báo cáo y học: "The rapid growth of a pleomorphic adenoma of the parotid gland in the third trimester of pregnancy" pdf

Báo cáo khoa học

... surgery and performed the final reading of the manuscript All authors have read and approved the final manuscript Competing interests The authors declare that they have no competing interests Received: ... monitoring of tumors of the salivary glands diagnosed during pregnancy Indications for early surgical intervention should be discussed on a individual patient basis in a multidisciplinary setting ... Consent Written informed consent was obtained from the patient for publication of the manuscript and accompanying images A copy of the written consent is available for review by the Editor -in- Chief...
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Báo cáo y học:

Báo cáo y học: "Accelerated tibial fracture union in the third trimester of pregnancy: a case report" ppt

Báo cáo khoa học

... to the injury and those related to the patient Factors related to the injury include whether the fracture is open or closed, the severity of soft tissue injury, the degree of contamination in ... that the main contributing factor for accelerated union by four weeks is most likely hormonal In pregnancy, there is an increase in the level of steroid hormones, initially with progesterone in the ... during definitive surgery, due to the potentially accelerated healing response A better understanding of the biology of bone healing is required especially in pregnancy Competing interests The...
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Báo cáo y học:

Báo cáo y học: "Open Access Torsion of a normal ovary in the third trimester of pregnancy: a case report" docx

Báo cáo khoa học

... journal Competing interests The authors declare that they have no competing interests AS was involved in the management of the case and wrote the manuscript draft VG conducted the literature ... Laparotomy was conducted through a grid-iron incision The appendix was normal in appearance Minimal bloodstained peritoneal fluid was noted on opening the abdomen The right ovary was gangrenous and had ... discovered with internal echoes and irregular walls Her hemoglobin was 11 g/dl and the white cell count was 10,500/mm3 The results of urine microscopy were normal Consent The opinion of a general...
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Báo cáo y học:

Báo cáo y học: "Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis" pps

Báo cáo khoa học

... proinflammatory cytokine IL-6 Interestingly, the UC-MSCs could downregulate the IL-6 production in the transwell but not the cell- to -cell contact system (Figure 3c) both in single time point and in dynamic ... were added in the lower well of the invasion plate, with FLSs (150,000) alone in the well inserts Forty-eight hours later, the inserts were stained with the cell stain solution and the OD 560 ... transwell system or cocultured in the cell- to -cell contact system in 24-well plates After 72 hours, MMP9 in culture supernatants were determined MMP9 production was inhibited both in the cell- to-cell...
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Báo cáo y học:

Báo cáo y học: "Stem cells in the genomic age" docx

Báo cáo khoa học

... Reprogramming for pluripotency Austin Smith (Institute for Stem Cell Research, Edinburgh, UK) has developed similar genetic reporter lines for investigating the question of how ES cells commit to the ... by our inability to derive rat ES cells Shinohara hinted that he was making progress in applying his findings to the rat Finally, Tariq Enver (University of Oxford, UK) described a mathematical ... exciting times ahead Lowell 315.3 comment stem cells, following the changes in their transcriptional profile as they escape from the stem- cell state and commit to differentiation When two cells...
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Báo cáo hóa học:

Báo cáo hóa học: " Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke" ppt

Hóa học - Dầu khí

... a piece of gelatin sponge, Page of 10 the temporalis and overlying skin were sutured Animals were then placed in the supine position and a midline incision was made in the neck The bilateral common ... Reddish-brown staining of Class II MHC was evident in the infarcted brain parenchyma (B-i), along the meninge (B-ii), areas near the ventricular lining and vascular wall near the hippocampus (B-iv) ... Conclusions The findings presented here provide further insights into the mechanisms of NSC in the regeneration of the CNS Should the MHC modulation mediated by NSC-derived neurotrophins be elucidated,...
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Báo cáo sinh học:

Báo cáo sinh học: " Risk factors in the development of stem cell therapy" pdf

Hóa học - Dầu khí

... stem cells that originate from the inner cell mass of a blastocyst stage embryo The embryonal carcinoma cells replicate and grow in cell culture conditions In 1981, embryonic stem cells (ES cells) ... by cell sorting to minimise the number of pluri/ multipotent stem cells in the cell preparation [86], or to separate tumourigenic stem cells from non-tumourigenic stem cells (by e.g cell sorting ... of the stem cells at these distant or non-target sites As noted earlier the local environment in which the stem cell resides in the recipient may influence the biological properties of the stem...
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báo cáo hóa học:

báo cáo hóa học:" MUC4 stabilizes HER2 expression and maintains the cancer stem cell population in ovarian cancer cells" ppt

Hóa học - Dầu khí

... membrane-bound mucin MUC1 maintains a small population of stem/ progenitor cells in the breast cancer (MCF7) cell line [11] The fact that the vast majority of MCF7 stem cell enriched SP cells express ... oncoprotein in pancreatic cancer cells [7] In the present study, we analyzed the expression of the HER2 protein in MUC4transfected ovarian cancer cells The exogenous MUC4 expression in ovarian ... ovarian cancer cells induce the aggressiveness of the cancer cells and enrich the cancer stem cell population It also showed that MUC4 is expressed in the ovarian cancer stem cell population...
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Báo cáo y học:

Báo cáo y học: "Preferential expression of potential markers for cancer stem cells in large cell neuroendocrine carcinoma of the lung. An FFPE proteomic study" pptx

Báo cáo khoa học

... Representative proteins up-regulated in LCNEC were AL1A1, AK1C1, AK1C3, brain-type fatty acid-binding protein (FABP) and b-enolase On the other hand, those in SCLC were brain acid soluble protein (BASP), ... those in SCLC in the region (y>3.84, z>3.84) on the y-z plane and those in LCC in the region (x>3.84, y>3.84) Nomura et al Journal of Clinical Bioinformatics 2011, 1:23 http://www.jclinbioinformatics.com/content/1/1/23 ... and SCLC The preferential expression of the cancer stem cell markers in LCNEC over SCLC suggests that the mechanism of increasing the extent of malignancy in LCNEC differs from that in SCLC Previous...
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báo cáo khoa học:

báo cáo khoa học: "Hepatocyte growth factor incorporated chitosan nanoparticles augment the differentiation of stem cell into hepatocytes for the recovery of liver cirrhosis in mice" pptx

Báo cáo khoa học

... which stem cells regenerate the respective parenchymal cells, heading to repair of the organs in vivo is yet to be completely understood Cell fusion, in which stem cells fuse with the somatic cell ... Inhibition of the proliferation of T cells thereby modulating the pro-inflammatory cytokines such as TNF-a and IL1bby MSC was reported [33-35] Less invasions of inflammatory cells in the MSC and ... protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo Int J Pharmacol 2002, 249:139-147 Neuman RE, Logan MA: The determination of collagen and elastin...
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Báo cáo y học:

Báo cáo y học: "Marked increase of procalcitonin after the administration of anti-thymocyte globulin in patients before hematopoietic stem cell transplantation does not indicate sepsis: a prospective study" pptx

Báo cáo khoa học

... Republic The study was approved by the institutional review board The purpose and procedures of the study were explained to participants, and written informed consent was obtained Interventions The ... conditioning PCT seems to have no predictive value of future infectious complications Both PCT and CRP have limited value in the diagnosis of infection during the administration of ATG Competing interests ... conditioning regimen was selected according to the underlying disease The ATG dose was selected according to donor-patient matching A test dose of ATG (20 mg) was given after the baseline (BL)...
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an investigation into the role of chemokines in haemopoietic stem cell quiescence

an investigation into the role of chemokines in haemopoietic stem cell quiescence

Tổng hợp

... cell in a state of dormancy or inactivity in which the cell is not dividing, therefore is in G0 phase of the cell cycle Quiescence should not be misinterpreted with other processes in which cells ... Similar observations were made in other systems containing stem cells, including the gut epithelium and epidermis (Cheung and Rando, 2013) Experiments in the haemopoietic system identified that adult ... maintaining the HSC quiescence pool through CXCR4 These cells have been reported in both the endosteal and the vascular areas within the BM niche in particular around the sinusoids in the vascular...
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Asymmetric cell division in the regulation of neural stem cell self renewel in drosophila melanogaster

Asymmetric cell division in the regulation of neural stem cell self renewel in drosophila melanogaster

Tổng hợp

... Each stem cell generates another stem cell and a sibling daughter cell destined to differentiate B Extrinsic versus intrinsic regulation of asymmetric division Extrinsic mechanism involves intercellular ... determinants during neuroblast asymmetric cell division results in both the daughter cells adopting a stem cell- like identity upon division In the absence of these basal targeting adaptor proteins ... external stimuli The physical contact between the Drosophila germline stem cell and its surrounding cap cells (in ovary) or hub cells (in testes) is a good example of how stem cells utilizing this mechanism...
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Identification of factors involved in the maintenance of embryonic stem cell self renewal and pluripotency 2

Identification of factors involved in the maintenance of embryonic stem cell self renewal and pluripotency 2

Cao đẳng - Đại học

... processing is indeed active in ES cells and that mature Lefty2 proteins are secreted into and deposited in the ES cell microenvironment 79 2.1.2.8 LEFTY2 maintains ES cell self renewal by inhibiting ... used in this assay to allow Lefty2 shRNA knockdown to differentiate the ES cells The cells were then dissociated with trypsin and replated at single cell density to allow the ES cells to expand into ... were used in the selection of genes The first criterion was the expression level of the candidate genes in pluripotent cell types of both mouse and human, such as in ES cells in the in- vitro scenario,...
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Identification of factors involved in the maintenance of embryonic stem cell self renewal and pluripotency 3

Identification of factors involved in the maintenance of embryonic stem cell self renewal and pluripotency 3

Cao đẳng - Đại học

... Nodal signaling might, as in the in vivo scenario, likewise influence ES cell fate decision in a dose dependent manner in vitro is addressed Interestingly, it was found that Nodal signaling is able ... signals dictate embryonic stem cell fates is also not entirely clear Conflicting roles of Nodal signaling in both the maintenance of ES cell self renewal and induction of ES cell differentiation have ... such In conclusion, the data presented in this thesis lead to the establishment of Lefty2 as an important regulator of embryonic stem cell fate Also, this thesis extends the current understanding...
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