oxidative stress and transforming growth factorβ1induced cardiac fibrosis
Báo cáo y học: "β Transforming growth factor-β-induced regulatory T cells referee inflammatory and autoimmune diseases" potx
Ngày tải lên :
09/08/2014, 06:22
... additional factors and/ or cofactors that
secondarily contribute to their function and that may
become prevalent in the absence of TGF-β and/ or if TGF-β
is dysregulated. The identification and intersection ... the
periphery, and to represent less than 10% of CD4
+
T cells
67
for the induction and/ or expansion of Treg to enhance
their role in autoimmunity, allergy, and graft rejection.
Conclusion
Innate and adaptive ... important new evidence
documents that Treg can be expanded and/ or induced de
novo from CD4
+
CD25
–
precursor T cells. How, where,
and if the size and function of this population can be
intentionally...
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Tài liệu OXIDATIVE STRESS AND DISEASES pptx
Ngày tải lên :
12/02/2014, 16:20
... orders@intechopen.com
Oxidative Stress and Diseases, Edited by Volodymyr Lushchak and Dmytro V. Gospodaryov
p. cm.
ISBN 978-953-51-0552-7
Oxidative Stress: Cause and Consequence of Diseases ... pathologies and oxidative modification of
proteins. Most antioxidant and related enzymes are targets for oxidative modification.
Hence, if oxidative stress was primary event, possible oxidative ... and Ortiz-Butron Rocio
Chapter 19 Oxidative Stress in Human Autoimmune Joint Diseases 437
Martina Škurlová
Chapter 20 Oxidative Stress in Multiple Organ Damage
in Hypertension, Diabetes and...
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- 1.9K
- 0
Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues ppt
Ngày tải lên :
06/03/2014, 19:20
... Ambient particulate air pollution induces
oxidative stress and alterations of mitochondria and gene expression in
brown and white adipose tissues. Particle and Fibre Toxicology 2011 8:20.
Submit ... (eWAT,
rWAT, and iWAT, left), and brown adipose depots (iBAT, and mBAT, right) by real-time PCR.n=8.*P < 0.05 vs. FA.
Xu et al. Particle and Fibre Toxicology 2011, 8:20
http://www.particleandfibretoxicology.com/content/8/1/20
Page ... insulin
resistan ce, oxidative stress, alteration of vasomotor tone,
vascular and visceral inflammation, adiposity, and
atherosclerosis in apolipoprotein E knockout (ApoE
-/-
)
mice and other several...
- 14
- 466
- 0
Báo cáo khoa học: Control of transforming growth factor b signal transduction by small GTPases pot
Ngày tải lên :
07/03/2014, 01:20
... of RhoA
and Rac1 GTPases and their downstram effectors
ROCK kinase, LIMK and cofilin, and the concomitant
upregulation of a-SMA gene expression [141].
TGFb-induced Rho GTPase activation and actin
remodeling ... essential for transforming growth factor-beta-
mediated stress fiber formation. J Biol Chem 276,
15362–15368.
159 Engel ME, Datta PK & Moses HL (1998) RhoB is
stabilized by transforming growth factor ... & Colicelli J (2008) Integration of
transforming growth factor beta and RAS signaling
silences a RAB5 guanine nucleotide exchange factor
and enhances growth factor-directed cell migration.
Mol...
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Báo cáo khoa học: A (1fi3)-b-D-glucan recognition protein from the sponge Suberites domuncula Mediated activation of fibrinogen-like protein and epidermal growth factor gene expression pot
Ngày tải lên :
16/03/2014, 16:20
... AGP2_BOVIN; O77802), and human (AGP1_HUMAN; Q15389 and AGP2_HUMAN; O15123). (iv) Ficolins: ficolin A and B from
pig (FICOLA_PIG; L12344 and FICOLB_PIG; L12345), mouse (FICOLA_MOUSE; AB007813 and FICOLB_MOUSE; ... (TECL5A-TACTR; AB024737.1 and TECL5B_TACTR; AB024738.1).
(iii) Angiopoietin: angiopoietin 1 and 2 precursors from mouse (AGP1_MOUSE; O08538 and AGP2_MOUSE; O35608), bovine (AGP1_BOVIN;
O18920 and AGP2_BOVIN; ... EGF and required for biological activity
[77], are also found in the sponge and are highly conserved
in domain 2. Likewise, amino acids, which are involved in
ligand-receptor binding [52] and...
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Báo cáo khoa học: Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice pdf
Ngày tải lên :
22/03/2014, 16:20
... Induction of DNA strand breaks and oxidative
stress in HeLa cells by ethanol is dependent on CYP2E1
expression. Mutagenesis 22, 189–194.
5 McKillop IH & Schrum LW (2005) Alcohol and liver
cancer. ... &
Pacher P (2005) Role of oxidative- nitrosative stress and
downstream pathways in various forms of cardiomyop-
athy and heart failure. Curr Vasc Pharmacol 3,
221–229.
33 Narula J, Pandey P, Arbustini ... evidence indicating that the over-
expression of CYP2E1 causes cardiac oxidative stress,
myocyte apoptosis and the DCM phenotype.
Materials and methods
Animals
The a-MHC-cTnT
R141W
transgenic mice...
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Báo cáo khoa học: Fragile X-related protein FXR1 controls posttranscriptional suppression of lipopolysaccharide-induced tumour necrosis factor-a production by transforming growth factor-b1 doc
Ngày tải lên :
22/03/2014, 21:21
... lipopolysaccharide-induced
tumour necrosis factor-a production by transforming
growth factor-b1
Tarnjit K. Khera
1
, Andrew D. Dick
1,2
and Lindsay B. Nicholson
1,2
1 Department of Cellular and Molecular Medicine, School of ... anti-inflammatory
cytokine transforming growth factor-b1 (TGF-b1) of
the proinflammatory cytokine TNF-a via the induction
of FXR1 is the focus of this article.
TGF-b1, a member of the large transforming growth
factor-b ... of interferon-gamma (IFN-gamma), IL-10,
IL-12 and transforming growth factor-beta (TGF-
beta) mRNA in synovial fluid cells from patients in
the early and late phases of rheumatoid arthritis
(RA)....
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Báo cáo khoa học: Effect of oxidative stress and involvement of poly(ADP-ribose) polymerase (PARP) in Dictyostelium discoideum development doc
Ngày tải lên :
23/03/2014, 07:20
... oxidative
stress (Fig. 4A,B). Under oxidative stress, partial inhi-
bition of PARP activity led to altered growth, suggest-
ing that oxidative stress could be leading to cell cycle
arrest [22] and ... during oxidative stress- induced
growth changes in D. discoideum. Under oxidative stress, the
growth curve showed a dose-dependent increase in the lag phase.
The log phase was shortened, and this ... transcription by oxi-
dative stress. Mol Biol Cell 15, 5659–5669.
23 Vohra I (2005) Effect of UV-C irradiation and oxidative
stress on Dictyostelium discoideum growth, development
and cell death. MPhil...
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Báo cáo khoa học: The silencing of adenine nucleotide translocase isoform 1 induces oxidative stress and programmed cell death in ADF human glioblastoma cells doc
Ngày tải lên :
29/03/2014, 09:20
... effects of BA, ATR and ANT1 siRNA on cell viability and glucose consumption. (A,B) Cell growth curves analyzed by
crystal violet assay in BA and vehicle-treated (A) and in ATR and vehicle-treated ... Scramble- and ANT1 siRNA-transfected U-87-MG cells, 24 and
48 h after transfection. (C) Cell growth curves analyzed by crystal violet assay in nontransfected U87-MG cells, and in Scramble- and ANT1
siRNA ... RNA
Fig. 2. Effect of ANT1 and ANT2-silencing on ADF cells. (A) Cell growth curves analyzed by crystal violet assay in nontransfected ADF cells,
and in Scramble- and ANT1 siRNA and ANT2 siRNA ADF-transfected...
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Báo cáo khoa học: Oxidative stress and apoptotic events during thermal stress in the symbiotic sea anemone, Anemonia viridis potx
Ngày tải lên :
30/03/2014, 10:20
... apoptosis protein and
heat shock proteins [47,48].
Caspase-like activity and oxidative stress
After the finding of caspase-like activities and a
response by these enzymes to heat stress, parallel ... stud-
ies and supports the occurrence of an oxidative stress
period in heat stressed A. viridis [24]. We suggest that
apoptosis induction could be the consequence of the
previous oxidative stress ... underlined.
Apoptosis and oxidative stress in bleaching S. Richier et al.
4190 FEBS Journal 273 (2006) 41864198 ê 2006 The Authors Journal compilation ê 2006 FEBS
Oxidative stress and apoptotic events...
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