oxidative stress and antioxidant therapy in parkinson disease
Tài liệu OXIDATIVE STRESS AND DISEASES pptx
Ngày tải lên :
12/02/2014, 16:20
... biology and oxidative stress in
Parkinson disease pathogenesis, Nature Clinical Practice. Neurology, Vol. 4, No. 11,
pp. 600-609.
Hermes-Lima, M. (2004a) Oxidative stress and medical sciences, In: ... researchers in the field of basic investigations
interested in the involvement of reactive oxygen species and oxidative stress in diverse
pathologies, medical scientists and practical physicians wishing ... if oxidative stress was primary event, possible oxidative modifications of
antioxidant enzymes may exacerbate diseases and define cell destiny. Finally, it is worth
mentioning advantages and...
- 624
- 1.9K
- 0
Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues ppt
Ngày tải lên :
06/03/2014, 19:20
... PM
2.5
onWATandBATspecificgenesin
different adipose depots. There are several major find-
ings in this study. First, exposure to PM
2.5
resulted in
oxidative stress in BAT. Second, exposure to PM
2.5
induced ... analyzed.
Finally, mitochondrial number was reduced in both
eWAT and iBAT in response to PM
2.5
exposure.
Recent studies have implicated PM
2.5
in in creased adi-
pose inflammation and insulin resistance ... PM
2.5
exposure
induced a marked increase in macroph age (F4/80
+
cells)
infiltration in eWAT. Next, we analyzed the changes in
uncoupling protein 1 (UCP1) in response to PM
2.5
exposure. As shown in Figure...
- 14
- 466
- 0
Báo cáo khoa học: Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice pdf
Ngày tải lên :
22/03/2014, 16:20
... radical
formation in diabetic rats induced by streptozotocin.
Life Sci 56, 1789–1798.
4 Hodges NJ, Green RM, Chipman JK & Graham M
(2007) Induction of DNA strand breaks and oxidative
stress in HeLa ... compounds, includ-
ing acetaminophen, benzene, carbon tetrachloride,
ethanol and N-nitrosodimethylamine. CYP2E1 is also
involved in the metabolism of endogenous aldehydes
and ketones and plays ... longitudinal sections are shown in (A) (magnifi-
cation ·20; scale bars = 1 mm). The hemotoxylin and eosin-stained sections of the left ventricle are shown in (B) and Masson’s trichrome
stained sections...
- 9
- 404
- 0
Báo cáo khoa học: Effect of oxidative stress and involvement of poly(ADP-ribose) polymerase (PARP) in Dictyostelium discoideum development doc
Ngày tải lên :
23/03/2014, 07:20
... oxidative stress- induced changes in
D. discoideum development. Interestingly, oxidative stress resulted in PARP
activation within 5 min that was inhibited by benzamide. Oxidative stress-
induced ... confirming PARP activation in
D. discoideum under oxidative stress.
PARP inhibition during oxidative stress- induced
growth changes in D. discoideum
PARP inhibition conferred protection against ... 3B).
Oxidative stress induces PARP activation
PARP activity in D. discoideum was assayed at various
time points (5, 10, 20 and 60 min and 4 h) after HA
stress. PARP activity was increased initially, and...
- 8
- 363
- 0
Psychiatric and Cognitive Disorders in Parkinson’s Disease pptx
Ngày tải lên :
28/03/2014, 22:21
... on both hands, mild rigidity and bradykinesia in the upper limbs,
gait slowness, and mild postural instability. He cried during the interview, and worried
about being unable to continue his work ... pallidotomy
Indications
Advanced disease with rigidity and bradykinesia, and a poor response to antiparkinsonian
medications
Disabling dyskinesias
Severe motor Xuctuations
Painful cramps and severe dystonias
Serious ... the cognitive and emotional side-eVects of
speciWc antiparkinsonian drugs, such as l-dopa, dopaminergic agonists,
amantadine, selegiline, and anticholinergic drugs.
In the eighth, and last, chapter...
- 241
- 273
- 1
Báo cáo khoa học: The silencing of adenine nucleotide translocase isoform 1 induces oxidative stress and programmed cell death in ADF human glioblastoma cells doc
Ngày tải lên :
29/03/2014, 09:20
... depletion
induced no major changes in cell cycle and in mito-
chondria aspect and network, and suggest that ADF
cells possess alternative mechanisms for providing
mitochondria with ATP and maintaining ... rup-
ture and were also negative to propidium iodide stain-
ing (data not shown), indicating that the plasma
membrane is maintained intact, allowing us to exclude
primary necrosis as the principal ... isoforms in astrocytes and astrocytic tumors. It
has been reported that ANT1 levels are increased in
reactive astrocytes [28] and that ANT2 levels are
increased in glial cells and neurons during hypertonic-
ity...
- 15
- 378
- 0
Báo cáo khoa học: Oxidative stress and apoptotic events during thermal stress in the symbiotic sea anemone, Anemonia viridis potx
Ngày tải lên :
30/03/2014, 10:20
... harboring the zooxanthellae (Fig. 6B).
Effect of heat stress on antioxidant defenses and
bleaching in animal tissue of A. viridis
The occurrence of oxidative stress in the animal tissue
(ectoderm and ... equations for determining chlorophylls a, b, c1
and c2 in higher plants, algae and natural phytoplank-
ton. Biochem Physiol Pflanzen 167, 191–194.
Apoptosis and oxidative stress in bleaching S. Richier ... mitochondria and chloroplasts
and can directly and ⁄ or indirectly cause caspase activa-
tion (reviewed in [25,27,49]). The delay observed in
our study between the antioxidant induction and the
caspase-like...
- 13
- 415
- 0
Tài liệu IMPLANT AND REGENERATIVE THERAPY IN DENTISTRY A GUIDE TO DECISION MAKING docx
Ngày tải lên :
16/02/2014, 21:20
... separate sinus augmentation procedure,
and to have a thorough understanding of the capa-
bilities of implants of various lengths in replacing
single missing maxillary posterior teeth.
Eliminating less ... will
receive or are receiving intravenous BIS ther-
apy include:
Before initiating intravenous BIS therapy:
Due to the recognized high level of co-
morbidity of dental diseases with BIS
therapy (84% of ... thus reducing the
buccolingual osseous ledging and eliminating re-
verse architecture, as well as forming an interprox-
imal osseous peak, had the greatest effect on col
Figure 1.4 As the in ammatory...
- 423
- 448
- 2
Tài liệu Báo cáo khoa học: The small heat shock proteins and their role in human disease pptx
Ngày tải lên :
19/02/2014, 18:20
... or
unfavorable, depending on the disease. As a case in
point, formation of huntingtin-containing inclusion
bodies in Huntington’s disease encourages cell survival,
whereas monomers and small inclusion bodies ... M & Vierling E (2001) The
expanding family of Arabidopsis thaliana small heat
stress proteins and a new family of proteins containing
a-crystallin domains (Acd proteins). Cell Stress Chap-
erones ... deficient in
desmin, again demonstrating inclusion body construc-
tion independent of intermediate fialments [62]. Inter-
estingly, inclusion body formation is slowed by
aB-crystallin, Hsp27 and HspB8,...
- 15
- 573
- 0
Báo cáo khoa học: Exogenous oxidative stress induces Ca2+ release in the yeast Saccharomyces cerevisiae potx
Ngày tải lên :
15/03/2014, 23:20
... Ca
2+
sensor protein calmodulin, which can bind
and activate calcineurin; this inhibits, at the post-tran-
scriptional level, the function of Vcx1p [11,15,16] and
induces the expression of PMC1 and PMR1 ... cell lines for studying the
effect of oxidative stress on the eukaryotic cells and
also an interesting model for studying antioxidants
in vivo [21–28]. Living in an oxidant-rich medium
under natural ... encoding
the regulatory subunit of calcineurin) under oxidative
stress was tested. It was noted that CNB1 deletion
resulted in an increase of tolerance to H
2
O
2
(Fig. 3B),
Oxidative stress and...
- 12
- 338
- 0
gene therapy in cardiovascular disease
Ngày tải lên :
10/04/2014, 22:11
... CARDIOVASCULAR DISEASE
CHAPTER 8
Gene Therapy in Cardiovascular Disease
VICTOR J. DZAU, M.D., AFSHIN EHSAN, M.D., and MICHAEL J. MANN, M.D.
INTRODUCTION
The explosive growth in understanding the changes in ... retention
in vitro and in vivo. Circulation 93:1439–1446, 1996.
George SJ, Baker AH, Angelini GD. Gene transfer of tissue inhibitor of metalloproteinase-
2 inhibits metalloproteinase activity and neointima ... transfer into vein grafts using viral vectors.
The vast majority of vein graft failures that have been linked to the neointimal
disease is part of graft remodeling after surgery. Although neointimal...
- 19
- 337
- 0