opinion or conclusion is supported by one or more other statements 4

báo cáo hóa học: " Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors" ppt

Ngày tải lên : 19/06/2014, 22:20

... controls Twenty -one days after implantation, cortices from left hemispheres were collected for protein and mRNA isolation For histological study, brain tissues were fixed in 10% formalin, embedded ... distribution among different plaque types in Alzheimer's disease: implications for its role in plaque progression Neuropathol Appl Neurobiol 1996, 22:3 34- 341 15 33 34 35 36 37 38 39 40 41 42 ... each tissue section spanned a total area of 37 241 .5 µm² These images were from hippocampal CA1 and two cortical regions, one at the midline and another at the superior aspects of the temporal cortex...

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Tài liệu Báo cáo khoa học: Reversible tetramerization of human TK1 to the high catalytic efﬁcient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration ppt

Ngày tải lên : 18/02/2014, 12:20

... and this form is more open than hTK1 Therefore, at present, it appears that the adenosine group is very loosely bound to hTK1 In the present work, the part of the phosphate donor that is necessary ... Acknowledgements This work was supported by grants from the Danish Research council and the Novo Nordic Research Council The skilful technical assistance of Marianne Lauridsen is gratefully acknowledged ... time- and storage-dependent differences in behaviour after dilution to lgÆmL)1 indicate that dissociation of the tetramer to the dimer is a slowly progressing process This is supported by the kinetic...

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Báo cáo y học: "Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells" ppsx

Ngày tải lên : 09/08/2014, 01:24

... arthritis J Immunol 2002, 169: 145 9- 146 6 34 Ji H, Pettit A, Ohmura K, Ortiz-Lopez A, Duchatelle V, Degott C, Gravallese E, Mathis D, Benoist C: Critical roles for interleukin and tumor necrosis factor ... scored for arthritis up to month and were included in the calculations None of the control mice developed arthritis Mice deficient in B cells or T cells were compared with WT mice for statistical ... capable of initiating disease independently of B and T cells during the effector phase of arthritis This is not an unexpected finding because CAIA is induced in naive mice by preformed anti-CII antibodies...

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All drawing stems from one or more of these forms pps

Ngày tải lên : 04/07/2014, 11:20

... 045 .jpg 046 .jpg 047 .jpg 048 .jpg 049 .jpg 050.jpg 051.jpg 052.jpg 053.jpg 0 54. jpg 055.jpg 056.jpg Page: [ Prev ] [ Next ] ...

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two or more friends

Ngày tải lên : 04/10/2012, 10:25

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KRONE - What is Patch by Exception

Ngày tải lên : 26/10/2013, 19:15

... uncluttered distribution frame allows for any temporary patches which have been set up to be easily seen by the network administrator giving better control and record accuracy The normal connection ... when patching is required, changes can be administered simply and easily, without delay or hassle to the network manager This lateral thinking by the KRONE designers, ensures Network managers ... PATCH BY EXCEPTION Many organisations have successfully implemented the Patch by Exception solution by establishing a maintenance contract with an installer who has progressively removed temporary...

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Tài liệu Cancer Pain Management: A perspective from the British Pain Society, supported by the Association for Palliative Medicine and the Royal College of General Practitioners docx

Ngày tải lên : 14/02/2014, 21:20

... bone pathological fracture 4. 2.1.1 Localised external beam radiotherapy • Localised external beam radiotherapy for metastatic bone pain is the usual modality for localised bone pain, and this ... ablation of the thyroid gland 4. 2.1 .4 Chemotherapy and hormone therapy Sections 4. 1.3 and 4. 1 .4 describe the palliative role of chemotherapy and hormone therapy This section draws attention to ... replaced by newer, more potent, drugs such as zolendronate and ibandronate • There is good evidence that in the adjuvant setting bisphosphonates reduce morbidity from bone metastasis, for example by...

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Tài liệu Báo cáo khoa học: TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor pdf

Ngày tải lên : 15/02/2014, 01:20

... space [ 14] HAI-1–NK1, which corresponds to the 40 kDa form, consists of the N-terminal region (N) and one Kunitz domain (K1), whereas HAI-1–NK1LK2, corresponding to the 58 kDa form, consists of ... systems (Minneapolis, MN, USA); anti-phospho-c-Met (Try12 34 ⁄ 1235) IgG, anti-phospho-p 44 ⁄ 42 mitogen-activated protein kinase (ERK1 ⁄ 2) (Thr202 ⁄ Tyr2 04) IgG and anti-p 44 ⁄ 42 mitogenactivated ... growth factor activator FEBS Journal 277 (2010) 48 88 49 00 ª 2010 The Authors Journal compilation ª 2010 FEBS T Hashimoto et al 10 11 12 13 14 15 16 17 18 inhibitor-1 (HAI-1) is essential for the...

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Tài liệu Báo cáo khoa học: Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT–MIM interaction pptx

Ngày tải lên : 18/02/2014, 04:20

... 277 (2010) 44 12 44 26 ª 2010 The Authors Journal compilation ª 2010 FEBS 44 21 Enhancement of calpain autolysis by IST1 Y Osako et al membranes [42 ] ALIX is recruited to plasma membranes by Gag proteins ... recognition by VPS4 ATPases Nature 44 9, 740 – 744 Kieffer C, Skalicky JJ, Morita E, De Domenico I, Ward DM, Kaplan J & Sundquist WI (2008) Two distinct modes of ESCRT-III recognition are required for VPS4 ... sites in the IST1 C-terminal region, which contains FEBS Journal 277 (2010) 44 12 44 26 ª 2010 The Authors Journal compilation ª 2010 FEBS 44 19 Enhancement of calpain autolysis by IST1 Y Osako...

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Tài liệu Báo cáo khoa học: Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1 pptx

Ngày tải lên : 18/02/2014, 13:20

... supporting information supplied by the authors Such materials are peer-reviewed and may be re-organized for online delivery, but are not copy-edited or typeset Technical support issues arising ... outlined to date is CamKII, which is known to play an important role in olfactory adaptation [20] By phosphorylation of adenylyl cyclase in OSNs, CamKII provides an important mechanism for the attenuation ... Immunohistochemistry Mice were raised and maintained according to governmental and institutional care instructions Immunohistochemistry was carried out on 14 lm horizontal sections, and ﬂuorescence...

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Tài liệu Báo cáo khoa học: Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases pptx

Ngày tải lên : 18/02/2014, 18:20

... Laboratory at the Cancer Research UK London Research Institute for performing the MS We also thank the members of the Garrett laboratory for useful discussion of the manuscript This work was supported ... directly phosphorylate CDK4 on Y17 and that this phosphorylation is independent of p27KIP1 The ﬁnding that Y17 phosphorylation is mediated by Src family kinases is completely novel and it is interesting ... inhibitor PP2 [20] In comparison, we also assayed the inhibition of puriﬁed recombinant kinases C-SRC, C-YES and p49WEE1 by PP2 using the 96-well plate format kinase assay p49WEE1 is a truncated form...

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Tài liệu Báo cáo khoa học: Staphylococcal enterotoxin C1-induced pyrogenic cytokine production in human peripheral blood mononuclear cells is mediated by NADPH oxidase and nuclear factor-kappa B doc

Ngày tải lên : 19/02/2014, 00:20

... Journal 2 74 (2007) 3633–3 645 ª 2007 The Authors Journal compilation ª 2007 FEBS C.-L Su et al 45 46 47 48 49 50 51 52 53 54 55 56 57 between IRAK -4 and the NADPH oxidase Biochem J 40 3, 45 1 46 1 Clark ... corresponding values of the group Time (min) Lucigenin chemiluminescence counts 10 12 68016 223689 312135 45 70 14 4 644 27 49 6952 5 848 33 ± ± ± ± ± ± ± 1187 18061* 27918* 52511* 44 959* 36 740 * 30 245 * ... (60 lM), MK 886 (10 lM), Wort (40 0 nM), or HIMO (25 lM) for h before treatment of SEC1 (1 ngÆmL)1) for 24 h Nuclear proteins were subjected to western blot analysis by using an anti-NF-jB p65...

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Tài liệu Báo cáo khoa học: Aggregative organization enhances the DNA end-joining process that is mediated by DNA-dependent protein kinase pdf

Ngày tải lên : 19/02/2014, 06:20

... provokes ATM-dependent dephosphorylation of histone H1 [42 ] A recent study demonstrates that whereas histone H1 is an inhibitory factor for EJ reaction, its phosphorylation by DNA-PK results in the ... proteinase K for 15 at 65 °C and subsequently for h at 37 °C for DNA analysis, and were analyzed by 1% agarose gel electrophoresis followed by staining with ethidium bromide For protein analysis, the ... for technical assistance and B S Strauss for reading the manuscript This work was supported by the Funds for Cross-over Research on Underlying Technology of Nuclear Energy and the Special Coordination...

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Tài liệu Báo cáo khoa học: Transcription of individual tRNA1Gly genes from within a multigene family is regulated by transcription factor TFIIIB pdf

Ngày tải lên : 20/02/2014, 02:21

... transcriptions [40 ,41 ] However, all our efforts to identify such a factor in B mori by PCR using primers based on the TRF sequences or western blots of different tissue extracts of B mori using Drosophila ... in 2) Likewise, transcription of Gly Gly tRNA1 -4 was inhibited 35% by competing tRNA1 Gly and much more effectively ( 75–80%) by tRNA1 Gly 6,7 Thus, tRNA1 -6,7 appeared to be a more effective ... extracts were prepared from freshly dissected silk glands of B mori larvae in the ﬁfth instar (day or 3) or from glands kept at )80 °C for up to a month For more details, see text (B) In vitro...

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Tài liệu Báo cáo khoa học: Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3 pdf

Ngày tải lên : 20/02/2014, 11:20

... precisely elucidating specific mechanisms regulating induction of fgl2 promoter activity in response to proinflammatory stimuli such as IFN-c or other viral factors Acknowledgements This work was supported ... 19, 246 8– 247 3 45 Tone, M., Powell, M.J., Tone, Y., Thompson, S.A & Waldmann, H (2000) IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3 J Immunol 165, 286–291 46 Schoenherr, ... construct that removed this major transcription start site and TATA box ()1320/)2 74) provided functional evidence for this conclusion When we performed functional analysis of the 5¢-flanking region...

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Tài liệu Báo cáo Y học: Thermostability of manganese- and iron-superoxide dismutases from Escherichia coli is determined by the characteristic position of a glutamine residue pdf

Ngày tải lên : 21/02/2014, 01:21

... Mn[Q 146 A] (r) and Mn[G77Q/Q 146 A] (d) or the pGHX(–) vector alone (·) metal in vivo and corresponds to a ratio around 20 times in favour of the ÔcorrectÕ metal This ratio of correct to incorrect ... SODs is not governed by one or even two residues, but is most likely accomplished by the concerted effects of a combination of key residues Further analysis of these and other mutant SODs is currently ... Biochem 44 , 276–287 43 Bradford, M.M (1976) A rapid and sensitive method for quantitation of microgram quantities of protein utilising the principle of protein binding Anal Biochem 72, 248 –2 54 44 Amann,...

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Tài liệu Báo cáo Y học: The binding of lamin B receptor to chromatin is regulated by phosphorylation in the RS region ppt

Ngày tải lên : 22/02/2014, 04:20

... G & Georgatos, S.D (1990) In vivo phosphorylation of the lamin B receptor Binding of lamin B to its nuclear membrane receptor is aﬀected by phosphorylation J Biol Chem 265, 41 81 41 84 34 Kuroyanagi, ... semiquantitatively by this method The effects of enzymes, inhibitors and other reagents on the cell cycle– dependent interaction could also be examined very easily by means of this method This method is applicable ... respectively This work was supported by a Grant-in-Aid from the Ministry of Education, Science, Sports and Culture of Japan, and grants from the Biodesign Research Project and for Project Research...

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Tài liệu Báo cáo Y học: Progressive apoptosis in chorion laeve trophoblast cells of human fetal membrane tissues during in vitro incubation is suppressed by antioxidative reagents pptx

Ngày tải lên : 22/02/2014, 07:20

... -cysteine (NAC) were from Dojindo Laboratories and Wako Pure chemical Ind Ltd, respectively Nordihydroguaiaretic acid (NDGA), glucocorticoids, cortisone and hydrocortisone were from Sigma Chemical Co ... tissue nor during incubation (group-3) During the in vitro incubation period, the inﬂuence of the existence of a low concentration of glucocorticoid (10 mg:mL21 hydrocortisone or cortisone) on ... apoptosis It has been reported for the anti-inﬂammatory mechanism of glucocorticoid, that the glucocorticoid receptor protein (which is a transcription regulatory factor) binds to the Jun domain,...

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Tài liệu Báo cáo Y học: Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine docx

Ngày tải lên : 22/02/2014, 07:20

... ACKNOWLEDGEMENTS This work is supported by grants from the National Health and Medical Research Council (NH & MRC) of Australia KB is supported by the Deutsche Forschungsgemeinschaft and the Bundesministerium ... eliminating hydrogen ﬂuoride, the peptides were solubilized in Aortae were dissected from Wistar-Kyoto or SpragueDawley rats and VSMC isolated by incubation in collagenase and elastase according to the ... alone (Fig 4B, P < 0.001) When homocysteine was added to VSMC grown on 10 lg of substrate-bound Ab1 40 or Ab1 42 , this toxicity was enhanced In the presence of homocysteine, Ab1 40 caused a 40 %...

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Báo cáo khoa học: Visfatin is induced by peroxisome proliferator-activated receptor gamma in human macrophages pdf

Ngày tải lên : 06/03/2014, 22:21

... diabetes [5–7] Visfatin is secreted by neutrophils in response to inflammatory stimuli and is regulated in monocytes by pro-inflammatory factors such as IL-1b, tumor necrosis factor alpha (TNF-a), ... pathways [19] This is similar to what has already been reported for other nuclear receptors, such as liver X receptor, for which short-term pretreatment with liver X receptor agonists significantly ... were transfected or not with non-silencing control or silencing siRNA against human visfatin (A), or treated or not with the visfatin inhibitor FK866 (100 nM) (B), or infected or not with PPARc-expressing...

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