omics application in heart failure novel diagnostic and prognostic markers to understand pathophysiology and f
Báo cáo y học: "Different effect of exercise on left ventricular diastolic time and interventricular dyssynchrony in heart failure patients with and without left bundle branch block"
... conditions resulting in a prolongation of left ventricular ejection and total LV systole (10,11) This effect of loading conditions on the duration of LV systole is a well documented finding in cardiac ... received during diastole Since both, a reduced myocardial perfusion reserve and diastolic heart failure, are an integral part of systolic heart failure any abnormal shortening of diastolic time, particularly ... systolic time and heart rate and expressed in seconds per minute Diastolic time was calculated as the cardiac length (RR interval) minus the duration of systole To define diastolic duration during...
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RECENT ADVANCES IN ROBUST CONTROL – NOVEL APPROACHES AND DESIGN METHODSE Part 1 pdf
... ranges for original system In contrast to classical methods of control theory, instead of zero –poles addition, the approach offers to add the equilibria to increase stability and sometimes to increase ... methods of design of robust control and some of them even become classical Commonly all of them are dedicated to defining the ranges of parameters (if uncertainty of parameters takes place) within ... can be represented in an information theoretic setting using entropy A toolbox for the robust fuzzy control using self-organizing features and quantum arithmetic is presented Integral variable...
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RECENT ADVANCES IN ROBUST CONTROL – NOVEL APPROACHES AND DESIGN METHODSE Part 2 potx
... guidance and support from the initial to the final level enabled me to develop an understanding of the subject I am very thankful for advises, help, and many offered opportunities to famous expert of ... University of Sfax, Sfax 3038 Automatic control at National School of Engineers of Sfax (ENIS) France 2,3 Tunisia Introduction Robust control theory is an interdisciplinary branch of engineering and ... Since its introduction in 1980’s, it has grown to become a major scientific domain For example, it gained a foothold in Economics in the late 1990 and has seen increasing numbers of Economic applications...
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RECENT ADVANCES IN ROBUST CONTROL – NOVEL APPROACHES AND DESIGN METHODSE Part 3 pot
... behaviour of the system output First step: The goal is here to obtain a fuzzy model from (57) By decomposing the nonlinear term and integring nonlinearities of x2 (t ) into + x1 ( t ) incertainties, ... set of indices i for which gi ( k ) is an external input, defining ß as the set of indices i for which y i ( k ) is an internal input or a neuron output, and defining ui ( k ) as the combination ... of this method to a limited category of applications A form of a similarity transformation can be used to correct this problem for { f : Rn×n → Rn×n } where f is a linear operator defined by f...
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RECENT ADVANCES IN ROBUST CONTROL – NOVEL APPROACHES AND DESIGN METHODSE Part 4 ppt
... output In other words, the nominal layer is to establish and approximate a state feedback control Finish training when the training performance is satisfactory Repeat this nominal layer training ... time-varying, parametric uncertainties, confined control inputs, and multiple control inputs These systems are represented by a finite dimensional differential system linear in control and linear in ... Hamiltonian system forward Evaluate the mismatch on the final constraints Find the sensitivity Jacobian for the final state and costate with respect to the initial costate value Using the Newton-Raphson...
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RECENT ADVANCES IN ROBUST CONTROL – NOVEL APPROACHES AND DESIGN METHODSE Part 5 pdf
... online training process However, it is difficult to acquire sensitivity information for unknown or highly nonlinear dynamics In addition, the local minimum of the performance index remains to be ... translations and dilations of the wavelets online The linearization technique was employed to transform the nonlinear wavelet functions into partially linear form to obtain the expansion of Γ in a Taylor ... tuning procedure to achieve satisfactory performance for specific models; some of them cannot achieve satisfactory performance under the changes of operating point; and some of them have not given...
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RECENT ADVANCES IN ROBUST CONTROL – NOVEL APPROACHES AND DESIGN METHODSE Part 6 potx
... Faf Fh kh - Cross sectional area of the hydraulic actuator piston - Actuator force - Combined nonlinear spring and damper force of the driver seat - Stiffness of the spring between the seat and ... on f is to be bounded by some function of the original states of f f es − f ≤ F (16) In order to have the system track on to a desired trajectory x(t) ≡ xd(t), a time-varying surface, S(t) in ... range of operating conditions for representing dynamical behavior of the system F = k1d + k2 d + C 1d + C d sgn( d ) where F - Force k1 - linear stiffness coefficient k2 - cubic stiffness coefficient...
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RECENT ADVANCES IN ROBUST CONTROL – NOVEL APPROACHES AND DESIGN METHODSE Part 9 docx
... trajectories are continuous The four case sliding surfaces are shown in fig 7, those are continuous The three case continuously implemented control inputs instead of the discontinuous input in Fig ... of the considered semi-waves is non decreasing Clearly this fact occurs iff the factor e(α − p )t is non increasing, i.e iff α − p ≤ , from which the proof derives From Theorems and easily follows ... case sliding surfaces are shown in fig 15, those are continuous also The three case continuously implemented control inputs instead of the discontinuous input in Fig 12 are shown in Fig 16 without...
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THE ROLE OF SURGERY IN HEART FAILURE - part 2 pps
... 30% and 50% of all patients presenting with heart failure have diastolic heart failure (left ventricle [LV] ejection fractionR50%) Diastolic heart failure was initially believed to be a rare and ... mortality from diastolic heart failure ranges from 5% to 15%, and admission rate for recurrent heart failure is 50% within the first months [1–4] The remaining 50% to 70% of patients present with systolic ... systolic heart failure that is clinically indistinguishable from diastolic heart failure It is important to identify patients who have systolic heart failure because they may be eligible for surgical...
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THE ROLE OF SURGERY IN HEART FAILURE - part 3 pptx
... Heart Failure Clin (2007) 139–157 Surgery for Heart Failure: Now Something for Everyone? Stephen Westaby, MS, PhD, FRCS* Oxford Heart Centre, John Radcliffe Hospital, Headington Oxford, ... Although donor hearts can be supplied to only to a tiny minority of patients who have heart failure, other surgical options may soon provide symptomatic relief for the majority The demand for treatment ... the landmark beginning of cardiac pacing (Fig 1) For the past 50 years cardiac surgery has been in a continuous state of flux In congenital heart disease palliative techniques have given way to...
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THE ROLE OF SURGERY IN HEART FAILURE - part 4 ppsx
... PhD, FRCS Oxford Heart Centre, John Radcliffe Hospital, Oxford, UK The mean age and risk profile of patients referred for cardiac surgery is constantly increasing Surgeons are now inclined to accept ... Mechanisms of postcardiotomy myocardial dysfunction Efforts to improve surgical results in patients who have heart failure depend on myocardial protection and preservation of contractile function in the ... replacement with a left ventricular ejection fraction (LVEF) less than 35% and a borderline transvalvular gradient [4] Intraoperative myocardial injury remains prevalent in the increasingly elderly...
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THE ROLE OF SURGERY IN HEART FAILURE - part 6 doc
... mortality from AMI falling from 11.2% to 9.4% from 1900 to 1999 [3] Improvements in mortality and morbidity over the past decade have been attributed to innovations in pharmacologic treatment, interventional ... options, and their rationale in the setting of life-threatening AMI and acute on chronic * Corresponding author New York Presbyterian Hospital, Milstein Hospital Building, Room 7-435, 177 Fort Washington ... with information that will shed light on the options that best suit the individual patient in a given set of circumstances Pathophysiology of acute ischemia Pathophysiology Occlusion of an infarct-related...
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THE ROLE OF SURGERY IN HEART FAILURE - part 8 pdf
... Such patients often show marked improvement in symptoms and ventricular function following revascularization Baseline left ventricular ejection fraction (LVEF) is the single most powerful variable ... is replaced by fibrosis and scarring after previous myocardial infarction There is increasing evidence that chronic LV dysfunction resulting from hibernating myocardium in patients who have severe ... Heart Failure Clin (2007) 211–228 Revascularization in Heart Failure: Coronary Bypass or Percutaneous Coronary Intervention? Sorin V Pusca, MD, John D Puskas, MD* Emory University School of...
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THE ROLE OF SURGERY IN HEART FAILURE - part 9 potx
... fibers forming the 3-D architecture of the wall and coordinating the delivery of forces generated by myocytes These forces are important determinants of diastolic and systolic stiffness and serve to ... revascularization in heart failure patients For a patient with heart failure to be considered a suitable candidate to truly benefit from coronary revascularization, ischemic heart disease * Corresponding author ... leads to heart failure (HF) progression; this progression is independent of the neurohormonal activation, according to the biomechanical model of HF recently introduced by Mann and Bristow [4]...
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THE ROLE OF SURGERY IN HEART FAILURE - PART 2 pdf
... [5] Withdrawal of nonsteroidal anti -in ammatory drugs, including aspirin, also seems to reduce the need for hospitalization for worsening heart failure [6,7] However, when standard pharmacologic ... obtain the first results of trials in 2007 Revascularization is not discussed further in this manuscript The initial enthusiasm for skeletal myoblast and stem cell transplantation into the failing ... matter Ó 2007 Elsevier Inc All rights reserved doi:10.1016/j.hfc.2007.05.005 heartfailure.theclinics.com Heart Failure Clin (2007) 275–288 Does Myectomy Convey Survival Benefit in Hypertrophic Cardiomyopathy?...
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THE ROLE OF SURGERY IN HEART FAILURE - PART 4 ppt
... allows the heart a period of relative rest in which functional improvement may be achieved by interrupting the vicious circle of increasing wall tension and functional impairment The hearts of a subset ... with the former systems, and infection done of the critical problems related to the size of the devicesdno longer plays a prominent role The remaining problem with these pumps alludes to thromboembolic ... treated with full antifailure medication, which, after a time of improvement, cannot avoid a trend toward further deterioration in most patients [13,14] Likewise the application of devices with...
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THE ROLE OF SURGERY IN HEART FAILURE - PART 6 pdf
... devices to assist the pumping function of the heart has resulted in a new vocabulary This has led to a surplus of confusion, even misunderstanding, extending from the characteristics and phenotypes ... understanding and refinement of the therapeutic orchestra available for patients in the advanced phase of heart failure have occurred, specifically with the introduction of highly specialized heart ... failure units and comprehensive multidisciplinary teams; new pharmacologic compounds, including angiotensin-converting enzyme (ACE) inhibitors, angiotensin-receptor blockers, spironolactone and...
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