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obesity as realm for the physician nutrition specialist

Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier

Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier

Tài liệu khác

... for 48 h The reactant was precipitated with distilled water, and then washed with distilled water and methanol The solid material was vacuum-dried at 50°C for 48 h The final product was identified ... pharmacokinetics was also assessed in rats to compare to the free drug Methods Materials Pullulan (Mw = 200,000) was purchased from Hayashibara (Tokyo, Japan) Epirubicin·HCl (EPI·HCl) was purchased from ... prepared as follows: EPI·HCl (10 mg) was dissolved in DMF (2 ml) and then triethylamine (TEA) was added to this solution to remove hydrochloride The mixed solution was stirred in the dark for 12 h...
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Tài liệu Copper and Fiber Labeling Software and Labeling Sheets docx

Tài liệu Copper and Fiber Labeling Software and Labeling Sheets docx

Phần cứng

... contains labels for the front and back of the hinged label SH ADCLS-TFP1RUA Adhesive label for ADC’s 2RU TFP Fiber Panel Each label sheet contains labels for the front and back of the hinged label ... ADCLS-TFP2RUA Adhesive label for ADC’s 5RU TFP Fiber Panel Each label sheet contains labels for the front and back of the hinged label SH ADCLS-TFP5RUA 3/08 • 106049AE  SH Adhesive label for ADC’s patch cords ... sheet for left side of block SH ADCLS-NGF144SCAL Adhesive label for ADC’s 144 Fiber NGF Blocks Each label sheet contains label sheet for right side of block SH ADCLS-NGF144LCAR Adhesive label for...
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Tài liệu Stability and Control of Large-Scale Dynamical Systems pptx

Tài liệu Stability and Control of Large-Scale Dynamical Systems pptx

Sức khỏe giới tính

... derivative The time derivative Even though the theory of vector Lyapunov functions was discovered independently by Bellman and Matrosov, their formulation was quite dierent in the way that the components ... whereas Matrosov allows for the components to be dened in the entire state space The latter formulation allows for the components of the vector Lyapunov functions to capture the whole state space ... satised; whereas a universal statement has the form: condition C holds for all x X For universal statements we often omit the words for all and write: condition C holds, x X The notation used...
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Tài liệu The Decline of Traditional Banking: Implications for Financial Stability and Regulatory Policy doc

Tài liệu The Decline of Traditional Banking: Implications for Financial Stability and Regulatory Policy doc

Ngân hàng - Tín dụng

... deterioration in the income advantages they once enjoyed on the asset side of their balance sheets The growth of the commercial paper and junk bond markets and the increased securitization of assets have ... as well as for derivatives-related exposures Properly measured, therefore, banks’ credit-risk exposures associated with their OTC derivatives activities not seem out of proportion to their other ... majority of both the Board of Governors of the Federal Reserve System and the Directors of the Federal Deposit Insurance Corporation as well as the secretary of the Treasury agreed Thus, the moral hazard...
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Tài liệu Báo cáo khoa học: Combinatorial approaches to protein stability and structure pdf

Tài liệu Báo cáo khoa học: Combinatorial approaches to protein stability and structure pdf

Báo cáo khoa học

... V47I, clearly has the same overall architecture as wild type repressor, but the C-terminus of helix has shifted away from the core to accommodate the overpacking (as indicated by the arrow) Interestingly, ... of those RNAs) By expressing green fluorescent protein from a ColE1 plasmid, cellular fluorescence reports the copy number of the plasmid and therefore rop functionality This screen has been applied ... stability has been derived from systematic studies of small model proteins like the T4 lysozyme, the B1 domain of protein G, lambda repressor, staphylococcal nuclease, barnase and rop, as well as the...
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Đề tài

Đề tài " Stability and instability of the Cauchy horizon for the spherically symmetric Einstein-Maxwell-scalar field equations " doc

Thạc sĩ - Cao học

... equations The reader can recover the full result of the proposition from the estimates for ν in Section For the slighter weaker result then, by virtue of the co-area formula, it suffices to bound the ... data such that for small enough U , the solution exists all the way up to the Cauchy horizon We are interested in determining the behavior of the mass parameter of the solutions as the Cauchy horizon ... small holds for the initial value problem with data S, and uniqueness in the large is thus a reasonable question to ask Yet as in the Kerr solution described in the introduction, the domain of...
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Báo cáo khoa học: Purine nucleoside phosphorylases from hyperthermophilic Archaea require a CXC motif for stability and folding pot

Báo cáo khoa học: Purine nucleoside phosphorylases from hyperthermophilic Archaea require a CXC motif for stability and folding pot

Báo cáo khoa học

... continuously for 210 at 30 °C The positive control was the reactivation of sRNaseA catalyzed by PDI (final concentration lm) The control for the non-enzymatic reactivation of sRNaseA was represented by the ... folding, the disulfide isomerase activity of these CXCcontaining peptides was assayed by monitoring the reactivation of scrambled RNaseA (sRNaseA) As shown in Fig 4, after 210 of incubation in the ... C-terminus of the yeast thiol oxidase Erv2p was found to be involved in the exchange of the de novo synthesized disulfide bridge with substrate protein [25] Moreover, it was demonstrated that a synthesized...
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Báo cáo khoa học: Effect of flanking bases on quadruplex stability and Watson–Crick duplex competition pptx

Báo cáo khoa học: Effect of flanking bases on quadruplex stability and Watson–Crick duplex competition pptx

Báo cáo khoa học

... using the nearest-neighbor method The DSITC for duplex formation decreased with the increase in the number of anking bases from to However, there was deviation from the decreasing DSITC values for ... 107 106 the binding enthalpy for duplex formation, which increased with the increase in the number of anking bases from to 6, and deviation from the increasing DHITC trend was observed for c-kitG8 ... sequences at both their ends The study shows that the presence of anking bases affects the thermodynamic stability of the G-quadruplex With an increase in the ank length, the increase in the more favorable...
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Báo cáo khoa học: Thermodynamic stability and folding of proteins from hyperthermophilic organisms doc

Báo cáo khoa học: Thermodynamic stability and folding of proteins from hyperthermophilic organisms doc

Báo cáo khoa học

... calculated The unfolding-rate constant for TkRNase HII is much lower than those for RNase HI from E coli and RNase HII from thermophilic Thermus thermophilus (Tt), whereas the refolding speeds for all ... temperatures The DCp for TkRNase HII is higher than that for TtRNase HII, explaining the more narrow range of temperatures where the hyperthermostable protein remains folded as compared to the thermostable ... protein from a hyperthermophile Biochemistry 43, 13859– 13866 Deutschman W & Dahlquist FW (2001) Thermodynamic basis for the increased thermostability of CheY from the hyperthermophile Thermotoga maritima...
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Báo cáo khoa học: The natural mutation by deletion of Lys9 in the thrombin A-chain affects the pKa value of catalytic residues, the overall enzyme’s stability and conformational transitions linked to Na+ binding pdf

Báo cáo khoa học: The natural mutation by deletion of Lys9 in the thrombin A-chain affects the pKa value of catalytic residues, the overall enzyme’s stability and conformational transitions linked to Na+ binding pdf

Báo cáo khoa học

... supports the role of the A-chain in affecting the conformation and catalytic properties of the B-chain, particularly in some insertion loops of the enzyme, such as the 60-loop, as well as in the geometry ... expresses the acylation rate By contrast, the decrease in the DK9 Km value is consistent with better accommodation of the substrate into the catalytic pocket of the unprotonated form of the mutant, as ... A-chain was released and the the native enzyme form disappeared for both WT and mutant thrombin (Fig 5) The kinetic rate constant of free A-chain release was 1.69 ± 0.03 · 10)2Æmin)1 in the WT form...
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Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx

Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx

Báo cáo khoa học

... multiexponential fit reflecting at least three resolved folding phases The fast phase, which accounts for % 87% of the amplitude of the fluorescence change, has an extrapolated folding rate in water ... representing the change in activation enthalpy, heat capacity and entropy of formation of the TSE for folding (U-à) Reported errors reflect the quality of the nonlinear least squares fit to the experimental ... are clearly evident in the NOESY data for WT*, P37A, P38A and A37A38 Further, Ile36 NH has the characteristic upfield shift that confirms that the C terminus of the helix and the C-capping motif are...
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Báo cáo Y học: Processing, stability, and kinetic parameters of C5a peptidase from Streptococcus pyogenes pptx

Báo cáo Y học: Processing, stability, and kinetic parameters of C5a peptidase from Streptococcus pyogenes pptx

Báo cáo khoa học

... des-Arg1bradykinin (synthetic) The mass accuracy was in the range of 0.1% Hydrolysis of protein and peptide substrates Treatment of the S512A C5a peptidase precursor with C5a peptidase was performed at 25 ... peptides in the supernatant fractions was measured spectrophotometrically at 574 nm The C5a peptidase-catalyzed hydrolysis of the 19-mer synthetic peptide VVASQLRANISHKDMQLGR was performed at 25 ... mutation was then subcloned into a pTrc99a expression vector where a kanamycin resistance cassette had been inserted into the ampicillin gene The plasmid pTrc99a (S512A C5a peptidase) was transformed...
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FINANCIAL LIBERALIZATION, MACROECONOMIC (IN)-STABILITY, AND PATTERNS OF DISTRIBUTION pptx

FINANCIAL LIBERALIZATION, MACROECONOMIC (IN)-STABILITY, AND PATTERNS OF DISTRIBUTION pptx

Tài chính doanh nghiệp

... and the monetary base was to be totally dependent on the purchases of foreign exchange by the CB Together with lower limits for the net international reserves and upper limits for PSBR as performance ... rates for the two indices at the end of 2000 Furthermore it programmed a 20% increase in the nominal TL price of a basket of 1US$+0.77 Euro Upper limits for the net domestic assets of the Central ... target either the nominal exchange rate or the interest rate, leaving the determination of the other to the interplay of the market forces The overwhelming evidence accumulated from the developing...
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Báo cáo khoa học: Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein potx

Báo cáo khoa học: Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein potx

Báo cáo khoa học

... distinguishes them from their mesophilic and thermophilic counterparts is their lower thermal stability [66] This could therefore be one explanation for the reduced stability that we observed for sbTTR as ... Pi was used as a control for these experiments Acknowledgements The authors wish to thank Uwe H Sauer and Tobias Hainzl for valuable discussions, and Terese Bergfors for critical reading of the ... however, was the low thermostability of the ecTRP protein, with a Tm value approximately 26 °C below the values for both sbTTR and hTTR (Fig 7) The inability of ecTRP to form fibrils at low pH can therefore...
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Báo cáo khoa học: Crystal and solution structure, stability and post-translational modifications of collapsin response mediator protein 2 pdf

Báo cáo khoa học: Crystal and solution structure, stability and post-translational modifications of collapsin response mediator protein 2 pdf

Báo cáo khoa học

... Thermofluor assays In both cases, the Tm was taken as the point of steepest ascent of the measured curve The number of replicates for each condition in the Thermofluor assays is given in parentheses ... sites The reasons for the concentration of the modifications to these areas in 3D space are currently not known, but they could include the accessibility of these areas towards modifications, their ... mgÆmL)1, and the crystal structure values for Rg, excluded volume and Dmax are as given by CRYSOL The theoretical I(0) was calculated for the crystal structure based on the I(0) of BSA The SAXS excluded...
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power system stability and control chuong (1)

power system stability and control chuong (1)

Điện - Điện tử

... determine the source of the sag If the current doubles when the voltage sags 10%, then the cause of the sag is on the load side of the current monitor point If the current increases or decreases 10–20% ... voltage waveforms Some machines compare portions of successive waveforms, and capture the waveform if there is a significant deviation in any portion of the waveform Others capture waveforms if there ... waveform when the current changes from zero to nearly 100 amps peak The shape of the waveform, and the phase shift with respect to the voltage waveform, confirm that this current increase was due to...
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power system stability and control chuong (2)

power system stability and control chuong (2)

Điện - Điện tử

... publish reliable data and information, but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequences of their use No part of this book ... together the core of knowledge from all of the many topics encompassed by the field The chapters are written primarily for the electric power engineering professional who is seeking factual information, ... accomplished the goals that were set Their contributions are, of course, most key to the success of the work I gratefully acknowledge their outstanding efforts Likewise, the expertise and dedication of the...
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power system stability and control chuong (3)

power system stability and control chuong (3)

Điện - Điện tử

... minimum In the Great Plains, the prevailing winds are from the south (Kansas, Oklahoma, and Texas) or north (the Dakotas) The energy in the winds from east and west may not be more than 10% of the total ... provide considerably more hassle to the landowner The original owner got the lease payment, and 20 years later the new owner gets the nuisance There is no incentive for the new landowner to be cooperative ... that the supply would be less If we assume the law of supply and demand to apply, the price of gasoline and natural gas would increase The possible increase is shear speculation, but could easily...
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power system stability and control chuong (4)

power system stability and control chuong (4)

Điện - Điện tử

... cathode through the outer circuit At the cathode the oxygen molecule interacts with the hydrogen ion and the electron from the outside circuit to form water The performance of the PEM fuel cell ... Only then can each H atom release an electron to form a hydrogen ion (Hþ) which travels to the cathode through the electrolyte At the same time, the free electron travels from the anode to the ... expansion and, as a result, the compressor and the expander must operate at the same time and must have the same air mass flow rate In the case of a CAES plant, the compressor and the expander can be...
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