nonreceptor tyrosine kinases and their roles in cancer
báo cáo hóa học:" RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation" pptx
Ngày tải lên :
18/06/2014, 15:20
... propagates inflammatory responses and is a significant RAGE ligand in the setting of sepsis and acute inflammation HMGB1 is an apparent autocrine/paracrine regulator of monocyte invasion, involving ... to consider their role in cancer and inflammation S100 proteins are a family of over 20 proteins expressed in vertebrates exclusively and characterized by two calcium binding EF-hand motifs connected ... family differ from each other mainly in the length and sequence of their hinge regions and the C-terminal extension region after the binding loops Ca++ binding induces a large conformational change...
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The chemical components of detergents and their roles in the washing process
Ngày tải lên :
11/07/2014, 16:10
... present in hard water and in soils, thus allowing surfactants to function correctly Phosphates prevent these ions combining with surfactants and rendering these inactive They also condense to increase ... and magnesium incrustations on fabrics and on the washing machine’s heating elements - stabilise alkalinity at the correct level throughout the washing process thus giving good soil removal and ... redissolve calcium and magnesium compounds present in the washing machine from previous washes, thus reactivating any remaining detergents and improving detergent performance No other single chemical...
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Cloning and characterization of diamine oxidase and glutamate decarboxylase genes of mustard (brassica juncea) and their roles in shoot morphogenesis in vitro
Ngày tải lên :
12/09/2015, 10:19
... Lai Lai and Dr Yu Hao, for their help and encouragement during my staying in Singapore Their presence has created an enjoyable and productive working environment and made my staying in Singapore ... lines of AtGAD-AS, AtGAD-S and AttGAD plants 214 xvii Summary There is accumulating evidence showing that polyamines (PAs), including putrescine (Put), spermidine (Spd) and spermine (Spm), and ... in siliques and rosette leaves, lower in flower and cauline leaves and lowest in stem and root (Soyka and Heyer, 1999) Unlike ADC1, ADC2 transcript was accumulated predominantly in siliques and...
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The ancient origin of NF kb ikb and thioredoxin and their roles in immune response
Ngày tải lên :
14/09/2015, 22:25
... dual and opposing roles in the regulation of NF-κB in the nucleus and cytoplasm In the cytoplasm, TRX interferes with the signals to IκB kinases, and blocks the degradation of IκB, thus maintaining ... is involved in the dimerization, DNA-binding and interaction with the inhibitory IκB (inhibitor of NF-κB) proteins The difference is that RelA, RelB and c-Rel have an activation domain in their ... kinase; IL-1β, interleukin-1β; iNOS, inducible nitric oxide synthase; LT, lymphotoxin; MCP-1, monocyte chemotactic protein-1; MIP-1α, macrophage inflammatory protein-1α; NIK, NF−κB-inducing kinase;...
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báo cáo khoa học: " Expression of Ets-1, Ang-2 and maspin in ovarian cancer and their role in tumor angiogenesis" pps
Ngày tải lên :
10/08/2014, 10:21
... been fully investigated in ovarian cancer In the present study, we examined the relationship between the expression of Ets-1 and its targets Ang-2 and maspin in ovarian cancer and their clinical ... different roles in angiogenesis: Ang-1 and Ang-4 are agonist ligands for Tie2 and induce tyrosin phosphorylation of Tie2, while Ang-2 and Ang-3 are antagonist ligands They bind to Tie2 without inducing ... of maspin in ovarian carcinoma Clin Cancer Res 2002, 8:2924-2932 doi:10.1186/1756-9966-30-31 Cite this article as: Lin et al.: Expression of Ets-1, Ang-2 and maspin in ovarian cancer and their...
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Characteristics of Leachate from Citrus Groves and their Changes in the Collecting Reservoirs in Matsuyama, Japan
Ngày tải lên :
05/09/2013, 10:17
... grove from points Sampling points St.1 and St.2 are in the same stream, and sampling point St.3 is in the other stream The two streams flow together to be one stream and the sampling point St.4 is ... and periphery of the Seto Inland Sea The location of the research area and the distribution of the citrus groves in Matsuyama region are shown in Fig Matsuyama is situated in Shikoku Island in ... grove were investigated and their behaviors in the collecting reservoirs were discussed The main results obtained from the investigation are as follows: 1) Nitrogen concentration in grove soil...
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A study on english food related idioms and proversbs and their equivalents in vietnamese
Ngày tải lên :
11/12/2013, 23:48
... confusing in defining, memorizing and using them To overcome these, some solutions are introduced in chapter III such as learning by heart, reading books, magazine, stories pictures and studying ... an insight into the similarities and differences in the use of language and images in English and Vietnamese idioms and proverbs II Some popular English idioms and proverbs relating to food and ... difference and similarities between English and Vietnamese idioms and proverbs Chapter 2: An investigation into English idioms and proverbs relating to food and their equivalence in Vietnamese...
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A study on possessive determiners in english and their equivalents in vietnamese
Ngày tải lên :
11/12/2013, 23:53
... commit errors when learning and using possessive determiners in English Errors in using “a” and “the” in possessive determiners In process of studying “possessive determiners”, Vietnamese learners ... determiners use for feelings and thoughts to the person [81] Too many people blame their failings and their unhappiness on luck Scientists have taken a great interest in his ideas (Collin Cobuild, ... when using “possessive determiners” and suggested solutions Errors in word order of possessive determiners and the head noun Errors in using “a” and “the” in possessive determiners ...
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Tài liệu Báo cáo khoa học: Direct identification of hydrophobins and their processing in Trichoderma using intact-cell MALDI-TOF MS docx
Ngày tải lên :
19/02/2014, 02:20
... hydrophobins HFBIII of H jecorina and T longibrachiatum, and SRH1 and HFB1 of T atroviride, involving signal peptides, Kex2type processing, and C-terminal amino acid cleavage (Table 2) In addition, the recorded ... terminal amino acid residues of all six hydrophobins providing this single match A rapid means of identifying peaks corresponding to hydrophobins in MALDI-TOF mass spectra was elaborated, making ... mass peak was missing (Fig 3B) Deviating post-translational processing of hydrophobins in H jecorina strains To investigate strain diversity with respect to metabolite production and low-mass proteomics...
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Tài liệu Báo cáo khoa học: The small heat shock proteins and their role in human disease pptx
Ngày tải lên :
19/02/2014, 18:20
... formation of huntingtin-containing inclusion bodies in Huntington’s disease encourages cell survival, whereas monomers and small inclusion bodies of huntingtin, a protein possessing abnormal polyQ ... aB-Crystallin R120 corresponds to aA-crystallin R116 and both are conserved a-crystallin domain arginines R120G aB-crystallin permits intermediate filament self association in vitro, although binding ... aAcrystallin requires this domain [66] Attachment of R116C aA-crystallin to Hsp27 and aB-crystallin increases in comparison to wild type, while binding to cC-crystallin and bB2-crystallin decreases...
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Báo cáo khoa học: Comprehensive sequence analysis of horseshoe crab cuticular proteins and their involvement in transglutaminase-dependent cross-linking potx
Ngày tải lên :
07/03/2014, 21:20
... other known cysteine-containing chitin-binding domains [14], such as plant chitin-binding proteins and horseshoe crab antimicrobial peptides with chitin-binding affinity [15–17] Rebers and Willis reported ... chitin-binding proteins in T tridentatus Amino acid compositions of high molecular mass (HMM) chitin-binding proteins HMM chitin-binding proteins resolved by 2D SDS ⁄ PAGE were categorized into ... with asterisks Numbers on the right indicate amino acid residue numbers and DE29 is involved in chitin binding In insects, cuticular proteins containing cysteine residues have not been reported,...
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Báo cáo khoa học: "Towards Finding and Fixing Fragments: Using ML to Identify Non-Sentential Utterances and their Antecedents in Multi-Party Dialogue" ppt
Ngày tải lên :
08/03/2014, 04:22
... start with training a model using a baseline set of features, and then add each remaining feature individually, recording the gain (w.r.t the fmeasure (f (0.5), to be precise)), and choosing the best-performing ... said in the introduction, the main task we want to tackle is to align (certain kinds of) NSUs and their antecedents Now, what characterises this kind of NSU, and what are their antecedents? In ... Computing Meaning, volume Kluwer Raquel Fern´ ndez, Jonathan Ginzburg, and Shalom Lappin a 2004b Classifying ellipsis in dialogue: A machine learning approach In Proceedings of COLING 2004, Geneva,...
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Báo cáo Y học: Fluorescent analogs of UDP-glucose and their use in characterizing substrate binding by toxin A from Clostridium difficile pdf
Ngày tải lên :
08/03/2014, 22:20
... as the metal binding event would be totally independent of the interactions involved in the enzyme–substrate complex The binding of MUG and Mg2+ are not independent, however, but instead are highly ... donor involved in the transferase Fig Diagram showing the thermodynamic equilibria and their dissociation constants involved in the binding of UDP-Glc, MUG and Mg2+ to TcdA Values shown in parentheses ... containing varying concentrations of UDP-Glc (0–145 mM) were studied The variable concentrations of UDP-Glc were obtained by starting with a stock solution containing all of the components including...
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Bioavailability and toxicity of cd to microorganisms and their activities in soil
Ngày tải lên :
15/03/2014, 23:21
... being an enzyme inhibitor, can have deleterious effects on membrane structure and function by binding to the ligands such as phosphate and the cysteinyl and histidyl groups of proteins (Collins ... 0.87% C different soils: River sand, Gley, Gray lowland, Andosol and Humic Andosol (pH 5.7–8.5) different soils—River sand, Gley, Gray lowland, Andosol and Humic Andosol (pH 5.7–8.5)q2% sludge ... ecophysiological indicator of heavy metal stress in soil (Anderson and Domsch, 1990; Brookes, 1995) qCO2 decreased in the heavily Cd contaminated soil over that in control during the first 2-d incubation (Landi...
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Cadmium and zinc interactions and their transfer in
Ngày tải lên :
15/03/2014, 23:22
... YA and MA in spring wheat lands, respectively, and 46 and 20 times in corn lands, respectively Soil Zn concentration at WA was and 1.5 times higher than the contents found at YA and MA in spring ... Ž1994., who, in their pot experiment, concluded that the contents of Cd and Zn in spring wheat parts Žstraw and grain increased with increasing the two metal concentrations in sandy soils The ... patterns of cadmium and zinc contents in different parts of the two crops grown in the field in uenced by non-ferrous metal mining and smelting operation; Ž2 transfer ratios and relationship models...
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Báo cáo khoa học: A study of microRNAs in silico and in vivo: diagnostic and therapeutic applications in cancer pot
Ngày tải lên :
16/03/2014, 01:20
... lymphomagenesis in mice [44] The miRNA miR-21 is overexpressed in many solid tumors, including breast, colon, lung, prostate and stomach, and in endocrine pancreas tumors, glioblastomas and uterine leiomyomas ... [48] miRNAs as biomarkers in cancer Their fundamental role in development and differentiation, and their pervasive corruption in lineagedependent mechanisms underlying tumorigenesis, suggest ... examined to date [8,52], a feature that could be particularly useful in diagnosing incident cancers in otherwise normal tissues Indeed, this approach discriminates normal and neoplastic tissues in...
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TALENT AGENTS, PERSONAL MANAGERS, AND THEIR CONFLICTS IN THE NEW HOLLYWOOD docx
Ngày tải lên :
16/03/2014, 17:20
... have a strong stake in maintain ing extended agreements in order to protect their ability to receive returns on the time and money they have invested in their clients during earlier, less profitable ... entered into an oral contract with one another stating that, in exchange for Waisbren’s assistance in developing Peppercorn’s projects, managing its business affairs, supervising its publicity, and ... (“The Wachs court intended to distinguish between the personal manager who, while operating in good faith, inadvertently steps over the line in a particular situation and engages in conduct which...
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Determinants and their applications in mathematical physics vein r , dale p
Ngày tải lên :
17/03/2014, 14:29
... respectively Determinants, their elements, their rejecter and retainer minors, their simple and scaled cofactors, their row and column vectors, and their derivatives have all been expressed in a notation ... (2) and (3) can be obtained formally from (B) and (D), respectively, by interchanging the symbols a and A and either raising or lowering all their parameters 3.5 3.5.1 The Adjoint Determinant ... or uninterested in the outstanding contributions to the theory and application of determinants made in the course of research into problems in mathematical physics These usually appear in Section...
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facile synthesis of porous a - fe2o3 nanorods and their application in ethanol sensors
Ngày tải lên :
19/03/2014, 16:48
... working temperature of 250 °C and 40% relative humidity (RH) An appropriate amount of ethanol vapor was injected into the closed chamber by a microinjector, and the sensor was exposed to air again ... diameter of about 10-15 nm and a length of about 200 nm After being calcined at 300 °C for h, the sample still maintains the rodlike 1-D morphology, as is shown in Figure 3c and d Compared with the ... carried out, and the resultant products were investigated by TEM (see Figure S1 in the Supporting Information) At a shorter reaction time of only min, there are almost no nanorods formed, and the...
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