nmr approaches to understanding protein specificity
Báo cáo y học: " Global approaches to understanding ubiquitination" pps
Ngày tải lên :
14/08/2014, 14:22
... conditions have been widely used to demonstrate covalent attachment of ubiquitin to specific proteins [40], as well as in proteome-wide approaches to identifying ubiquitinated proteins, as discussed below ... were divided into small pools and incubated with interphase and mitotic oocyte extracts Proteins that disappeared specifically from mitotic extracts were isolated, and this led to the identification ... F-box protein family and they also include the Ring-H2 protein Hrt1 (also known as Roc1 or Rbx1) [23] The substrate specificity of SCFs depends on the different F-box proteins that are tethered to...
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Molecular and computational approaches to understanding keloid scarring
Ngày tải lên :
10/09/2015, 15:48
... receptor 137B GPR153 G -protein- coupled receptor 153 GPSM2 G -protein signaling modulator GRB10 Growth factor receptor-bound protein 10 HATH Homologous to amino terminus of HDGF HDGF Hepatoma-derived ... resistance to apoptosis Keloid fibroblasts was found to be more resistant to Fas mediated apoptosis (Chodon et al 2000) and the overexpression of insulin-like growth factor-1 (IGF-1) receptor inhibited ... Tumor necrosis factor alpha-induced protein TNFAIP6 Tumor necrosis factor alpha-induced protein TNFSF10 Tumor necrosis factor superfamily member 10 TGF-β Transforming growth factor beta VEGF Vascular...
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Tài liệu Báo cáo khoa học: Combinatorial approaches to protein stability and structure pdf
Ngày tải lên :
19/02/2014, 12:20
... to understand what makes proteins ÔtickÕ and to engineer proteins with native-like properties In this review we discuss combinatorial approaches toward understanding protein structure and stability ... vivo activity of proteins (barnase, chorismate mutase, triosephosphate isomerase), usually linked to cellular survival Selecting for native-like proteins Combinatorial approaches to protein biophysics ... fluorescent protein to the C-terminus of analyte proteins [46,47] Cellular fluorescence was found to correspond to the solubility of the analyte protein (implying correct folding), presumably due to aggregation...
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Báo cáo khoa học: The use of recombinant protein and RNA interference approaches to study the reproductive functions of a gonad-stimulating hormone from the shrimp Metapenaeus ensis ppt
Ngày tải lên :
16/03/2014, 05:20
... rMeMIH-B into females to further confirm its gonadstimulatory effect To demonstrate the specificity of rMeMIH-B in gonad maturation, a control group injected with rMeMIH-A was included As compared to the ... rMeMIH-B Fig Histogram showing the relative expression levels of MeVg1 in (A) hepatopancreas and (B) ovary explants after exposure to different concentrations (i.e from 0.3 pM to 0.3 lM) of rMeMIH-B ... the hepatopancreas serves as an extraovarian source for the final synthesis of vitellin The newly made vitellogenin is expected to be secreted rapidly into the hemolymph and transported to the...
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Understanding Tuberculosis – New Approaches to Fighting Against Drug Resistance Edited by Pere-Joan Cardona potx
Ngày tải lên :
23/03/2014, 17:20
... Drugs near the top of the list are more effective and less toxic while drugs placed near the bottom of the list are less effective or more toxic, or more difficult to obtain Resistance to one drug ... 38kDa protein Universidad Nacional Autónoma de Mexico Prime Streptomyces live Recombinant streptomyces vector expressing multiple T and B epitopes from M.tb ID93 in GLASE Recombi- adjuvant nant Protein ... more akin to that for cancer than to that for infection It has a mortality rate of up to 80%, which depends on a number of factors, including: (1) How many drugs the organism is resistant to (the...
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Understanding Tuberculosis – Global Experiences and Innovative Approaches to the Diagnosis Edited by Pere-Joan Cardona potx
Ngày tải lên :
31/03/2014, 00:20
... 2001; Tortoli et al., 2001) The LiPa assay is able to detect up to 14 different species of mycobacteria (Table 3) and results are interpreted according to a flowchart decision scheme (Tortoli ... respiratory specimens (D'Amato et al., 1995) Other studies showed sensitivity and specificity for the assay ranging from 70.4% to 79.5% with specificity greater than 98% when compared to culture ... sensitivity and specificity of the acridinium ester labeled probes was comparable to that of the radioisotope labeled probes (Goto et al., 1991; Lebrun et al., 1992) Similar to the SNAP probes,...
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Báo cáo sinh học: "An automated stochastic approach to the identification of the protein specificity determinants and functional subfamilies" pot
Ngày tải lên :
12/08/2014, 17:20
... species They bind DNA operator sequences responding to the effector molecule We considered a subset of proteins, differing in their specificity to the effector and the operator sequence, that included ... alignment Then, for a protein of unknown specificity, it is possible to assign it to one of the specificity groups by the highest PWM score This allows us to augment the initial specificity groups ... proteins with the same specificity (specificity groups), and a set of positions that account for differences in specificity among the proteins (SDPs) We compared the performance of SDPclust to...
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Evaluation of different approaches to protein engineering and modulation
Ngày tải lên :
05/10/2015, 22:04
... displayed protein to be free Display on the T7 phage allows the C-terminus of the displayed protein to be free For display onto the M13 phage, SrtA was fused to the N-terminus of gene III To display proteins ... adding on tags like biotin to a protein allows it to be specifically immobilized onto an avidincoated surface [10, 11, 22] 1.1.3 The three different approaches to protein engineering and modulation ... report, three different approaches to protein engineering and modulation were evaluated As one of the approaches to protein engineering, a strategy for the immobilization of proteins site-specifically...
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Approaches to Establish a Modeling WWTP with a Case Study in Qinghe WWTP
Ngày tải lên :
05/09/2013, 09:08
... the final step is to join them into the object WWTP With mathematic models brought into WWTP software, and software combined into the monitoring and control system, the monitoring and control ... still many things to to before it works in the real WWTP The mathematic models should be adjusted to real plant behavior, which means to adjust the parameters and calibrate the model to adapt the ... correspond to the sensors It also needs to some programme to achieve the data transfer from sensors or apparatus to the control system After the whole network is established, we still need to test...
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Tài liệu A Guide to Understanding Color Communication pdf
Ngày tải lên :
19/01/2014, 13:20
... be used to create those boundaries Additional tolerancing formulas, known as CMC and CIE94, produce ellipsoidal tolerances Figure 14: CIELAB tolerance box b* CIELAB Tolerancing When tolerancing ... Commercial factor (cf) of tolerances 17 Color Differences, Notation and Tolerancing continued CIE94 Tolerancing In 1994 the CIE released a new tolerance method called CIE94 Like CMC, the CIE94 tolerancing ... difference in hue Figure 13: Tolerance ellipsoid ∆E* = total color difference value Refer to Figure 11 on page 10 a* Visual Color and Tolerancing b* Standard As a result, our tolerance for an acceptable...
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Slide an investigation into some approaches to vocabulary teaching and learning and the application of games in teaching and learning vocabulary at pre – intermediate level at foreign language center – haiphong university
Ngày tải lên :
29/01/2014, 14:36
... allow students to practice language skills (Lee, 1995) Games encourage learners to interact and communicate with one another When taking part in the games learners have to talk to express or ... your classmates help you to learn vocabulary through games? a b c d Help you to guess unknown words Help you to recall the words you have learnt but forgotten Help you to remember words from the ... bringing fun to classes Games can provide language practice Games encourage learners to interact and communicate with one another Games can motivate learners by bringing fun to classes Games...
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Tài liệu Community Approaches to Child Health in Malawi: Applying the Community Integrated Management of Childhood Illness (C-IMCI) Framework docx
Ngày tải lên :
12/02/2014, 12:20
... growth monitoring Multi-sectoral platform: Linking health efforts to those of other sectors in order to address determinants of ill health and sustain improvements in health The multi-sectoral platform ... women come together in a Care Group every two weeks to learn life-saving health messages from a health educator Each woman is then responsible to teach the health lessons they learn to 10–15 of ... Participatory research methods and community-based monitoring and evaluation efforts are important tools for communities to learn about and assume responsibility for these behaviors Ibid Community Approaches...
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Tài liệu Báo cáo khoa học: Chemical approaches to mapping the function of post-translational modifications ppt
Ngày tải lên :
18/02/2014, 17:20
... application to modified protein (glycoprotein) synthesis Chemical strategies in glycoprotein synthesis The chemical attachment of glycans offers an alternative, pragmatic route to homogeneous glycoproteins ... using glycoSeS to proteins in a one-pot protein glycosylation method [55] Thus, natural sugars can be stripped from a natural protein and reinstalled siteselectively into an alternative protein scaffold ... moieties to protein scaffolds is required for the correct function of the modified protein [58], either as a mediator of membrane association or as a determinant for specific protein protein interactions...
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Tài liệu Your guide to understanding car hire pptx
Ngày tải lên :
19/02/2014, 04:20
... few ways to reduce your excess to zero Super CDW A top up policy from the car rental company itself, usually payable when you arrive at the counter to collect the car which can cost up to £15 per ... chains to get to your destination The other key is snow tyres Find out if they are extra or if it is a legal requirement for cars to have them In Austria for example it is a legal requirement to ... the first few hours and then per day If you want to extend your car booking then call up the agent to notify them Mileage Unlimited mileage tends to be the norm However, if you are leaving car...
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Tài liệu A Comparison of Approaches to Large-Scale Data Analysis pdf
Ngày tải lên :
19/02/2014, 12:20
... required DBMS-X to be running in order to adjust them, it was unfortunately easy to lock ourselves out with no failsafe mode to restore to a previous state Vertica was relatively easy to install as ... required us to (1) write to a custom tuple object using Hadoop’s API, (2) modify our data loader program to transform records to compressed and serialized custom tuples, and (3) refactor each benchmark ... are two ways to load data into Hadoop’s distributed file system: (1) use Hadoop’s command-line file utility to upload files stored on the local filesystem into HDFS or (2) create a custom data loader...
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Tài liệu Báo cáo khoa học: Computational approaches to understand a-conotoxin interactions at neuronal nicotinic receptors doc
Ngày tải lên :
19/02/2014, 12:20
... subtype, thanks to the large amount of the receptor obtained from the electric organ of the Torpedo marmorata ray and availability of selective pharmacological tools like the snake a-neurotoxins The ... determinants have been mapped and a-conotoxins appear to bind mainly to loop C, but also clearly extend to microsites above this loop and on the b9b10 hairpin Indeed, a-conotoxins act at the competitive ... Anglister, J (2002) The mechanism for acetylcholine receptor inhibition by a-neurotoxins and species-specific resistance to a-bungarotoxin revealed by NMR Neuron 35, 319–332 25 Yassin, L., Samson, A.O.,...
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