nature s crystal engineers how proteins manipulate the microstructure and properties of minerals
Báo cáo khoa học: What’s in a covalent bond? On the role and formation of covalently bound flavin cofactors doc
Ngày tải lên :
16/03/2014, 01:20
... Fig Surface representations of several covalent flavoenzyme structures and the corresponding substrates, illustrating the open active sites of bicovalent flavoproteins The protein structure images ... activity and other biochemical properties is fundamentally different from assigning the role of covalent flavinylation on the basis of these effects Investigations aimed at assigning the importance of ... noncovalent flavoproteins, flavin analogs have been used to explore mechanisms and effects of flavin binding, and some examples are presented and discussed below A study of covalent flavinylation of the flavoprotein...
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Báo cáo khoa học: Structure analysis of the flavoredoxin from Desulfovibrio vulgaris Miyazaki F reveals key residues that discriminate the functions and properties of the flavin reductase family pdf
Ngày tải lên :
07/03/2014, 02:20
... Which structures determine the unique functions of these avin proteins? In this study, we present the crystal structure of DvMF avoredoxin and discuss the key residues for ligand binding and metal ... peaks at each of these sites These densities were assigned as zinc ions derived from the crystallization solution as an additive The zinc ion closest to FMN, Zn201, is coordinated by the Sc atom ... domains of BenC, which is the reductase component of benzoate dioxygenase reductase The crystal structure of BenC [27] shows that Cys307, which corresponds to Cys412 of the entry, is only A from the...
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Báo cáo khoa học: Effect of mutations in the b5–b7 loop on the structure and properties of human small heat shock protein HSP22 (HspB8, H11) pptx
Ngày tải lên :
23/03/2014, 07:20
... to the b8 strand of the other sHsp The primary structure of the a-crystallin domain of human sHsp is very conservative and the loop connecting the b5 and b7 strands is shorter than the corresponding ... aB-crystallin, the b7 strand is only four residues long [16] whereas, in the model of HSP27, the same strand is ten residues long [18] However, the overall structures of aB-crystallin and HSP27 ... predicted by these two models are very similar, and the positions of the b-strands correlate well with the corresponding positions of the b-strands in M jannaschii Hsp16.5 and T aestivum Hsp16.9 (Fig...
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Mafiaboy How I Cracked the Internet and Why It's Still Broken
Ngày tải lên :
22/02/2013, 17:05
... alias was being reported in the press They had moved surprisingly fast "The FBI sought to question several hackers Tuesday in its investigation into last week 's attacks against major Web sites, ... of harming anyone He was pissed off about business and let off some steam over the phone For that, the police had arrested him Their pressure tactics made him only more resolved to see me stand ... c-commerce sites and had compromised hundreds of servers to get the job done, but I couldn't see how this translated into hundreds of millions of dollars in damage My attacks shut the sites down;...
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Tài liệu Cleaner Water in China? The Implications of the Amendments to China’s Law on the Prevention and Control of Water Pollution pptx
Ngày tải lên :
18/02/2014, 04:20
... items covered by federal WEQ standards or establish local standards for items not covered.84 The development of these standards is similar to the standards in the United States The EPA sets treatment ... governments may create local standards for items not covered by the WEQ standards and must report their standards to the State Council.80 Using the WEQ standards and the country s economic and technological ... Discharge Standard, http:// english.mep.gov.cn/standards_reports/standards/water_environment/Discharge_standard/ (last visited May 5, 2009) Only abstracts of the standards are available on the...
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Tài liệu Báo cáo khoa học: Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae docx
Ngày tải lên :
19/02/2014, 07:20
... membrane proteins from the column was monitored by SDS ⁄ PAGE of every second fraction and subsequent Coomassie staining of the gels To raise mono-specific antisera, samples of the outer membrane proteins ... proteins exists, however, the Coomassie-stained profile of membrane proteins suggests Om45 and Om14 are present at similar levels in the outer membrane, and their steady-state levels are tightly ... within the intermembrane space, and the proteolysis must therefore represent a loss of 2 kDa from the N-terminus Given there are seven arginine and lysine residues spread through the N-terminal stretch...
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf
Ngày tải lên :
19/02/2014, 16:20
... residues Asn29fiGly41) Letters denote the five residues of one of the three sides of sbwAFP or six residues of one of two sides of TmAFP The strands that make up the three, parallel b-sheets of the ... motif Otherwise, there is very little isoform substitution of TXT residues, due to the tight coil structure The conservation of Gly and Asn residues is seen on the right side of each structure ... Ó FEBS 2004 3286 S P Graether and B D Sykes (Eur J Biochem 271) Fig Fish AFP structures and model The structures of the fish AFPs are shown as ribbon diagrams with coil structure shown as yellow,...
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Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot
Ngày tải lên :
21/02/2014, 15:20
... oligomeric state of the samples was not assessed at the high concentrations used for the ROA experiments and the possible effects of potential associations were not taken into account in the discussion ... DSC, of caseins, synucleins and tau, together with several mutants of a-synuclein and tau that cause neurodegenerative diseases The ROA spectra of all these proteins are very similar to those ... Parkinson 's disease Unfortunately the quality of some of these synuclein ROA spectra is generally not as good as that of the caseins due in part to the high concentrations of buffer salts Figure shows...
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Báo cáo khoa học: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris pdf
Ngày tải lên :
06/03/2014, 09:22
... YbaS The C-a locations and side-chain orientations of the seven conserved residues are similar among these glutaminases, suggesting that these residues have similar functions On the basis of the ... not shown) Figure shows the active sites of Mglu and Bacillus glutaminase in the presence and absence of the ligands The l-glutamate of Mglu is located near the seven conserved amino acid residues ... be the catalytic nucleophile [5] On the basis of their crystal structures and the conserved amino acid residues (aa) of their active sites, these glutaminases are classified into a large group of...
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The Benefits and Costs of the Clean Air Act from 1990 to 2020: U.S. Environmental Protection Agency Office of Air and Radiation potx
Ngày tải lên :
15/03/2014, 16:20
... The primary purpose of emissions analysis in this study is to estimate how emissions change over time and across our scenarios, so we can estimate costs of reducing emissions and the benefits ... by the results of our analysis of CAAA-related emissions reductions, and in some cases, costs and emissions reductions are measured concurrently As with the emissions analysis presented in the ... these emissions estimates: For emissions from area sources, we projected emissions from the two sectors responsible for the majority of emissions – construction and wood stoves – using source-specific...
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Báo cáo khóa học: S-(2,3-Dichlorotriazinyl)glutathione A new affinity label for probing the structure and function of glutathione transferases potx
Ngày tải lên :
16/03/2014, 16:20
... between 250 and 190 nm Molecular modelling Structure manipulations and analysis were performed using the PYMOL software [41] Results and Discussion Synthesis of SDTG SDTG was synthesized by nucleophile ... reaction of SDTG at the binding site of one subunit changes the conformation of the other subunit, thereby completely abolishing reaction of SDTG with the second subunit Analysis of the crystal structure ... experiments The results showed that the first-order rate constant for SDTG hydrolysis was 1.2 · 10)5 min)1 This corresponds to 0.07% and 0.03% of the rate observed for the slow and fast phase, respectively...
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how phreaks anarchist the kkk and swp compare to big broth
Ngày tải lên :
21/03/2014, 22:04
... groups are the Ku Klux Klan, theNeo-Nazis, and the Skinheads The reason why the Ku Klux Klan isseparate from the Neo-Nazis and the Skinheads is because the Ku KluxKlan 's hatred and violence is aimed ... a lot of their computers and systems Many of the popularPhreaks have connections into agencies like the Secret Service, NSA, etc and can get all sorts of information The Secret Service has beenmaking ... includes fatigues, flight jackets, suspenders that hang down, and steel-toed boots or Doc Martens Themost obvious thing about one is their shaved head These people standout purposely Unlike the Brotherhood,...
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The Value and Impacts of Alternative Fuel Distribution Concepts- Assessing the Army’s Future Needs for Temporary Fuel Pipelines pptx
Ngày tải lên :
23/03/2014, 02:20
... Hoseline Units There is, too, the capability of the other two tactical systems described in Chapter Three, the Assault Hoseline and the TWDS, to consider Each of the associated units is sized and ... capable of moving large quantities of liquid products, though not doctrinally considered wholesale systems, are included in this discussion The first of these is the Army s Assault Hoseline system The ... development), the Assault Hoseline, and the Tactical Water Delivery System The chapter then moves on to an analysis of the ability of these various systems to meet the set of future requirements Inland...
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How Teens Use Media - A Nielsen report on the myths and realities of teen media trends pdf
Ngày tải lên :
23/03/2014, 03:20
... shows up in the constant and frenetic quest to understand how teens use media, made murky by assumptions that teens somehow behave radically differently than their parents and other consumers ... many of the markets Nielsen tracks Consider mobile Web: as of Q1 2009, 37% of U .S mobile subscribers 13–17 accessed the Internet on their phone—this ranks U .S teens second, behind 50% of China s ... process Understanding the reality of how teens use media is critical—not just for business, but for civic, cultural and social pursuits This paper examines teens in the U .S and in many of the international...
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Báo cáo khoa học: Comparative proteomic analysis identifies proteins associated with the development and progression of colorectal carcinoma pot
Ngày tải lên :
23/03/2014, 03:20
... over-expression of the three proteins was significantly associated with the genesis and progression of CRC The functional implications of the alterations in the levels of these proteins are discussed ... development and progression of CRC Further functional and clinical analysis of the proteins is necessary to elucidate their precise role in the process of CRC and the formation of metastases Experimental ... mucosa and CRC tissues A representative immunohistochemistry staining is shown in Fig The rates of RhoGDI, S1 00A9 and LASP-1 over-expression in normal mucosa, nmCRC and mCRC tissue are shown...
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Báo cáo khoa học: Purification and properties of the glutathione S-transferases from the anoxia-tolerant turtle, Trachemys scripta elegans pdf
Ngày tải lên :
23/03/2014, 15:20
... membranes such as reactive alkenes, epoxides, hydroperoxides and aldehydes These may be the primary substrates of the microsomal or membrane-bound GST in the same way as they are the substrates for Se-dependent ... suggestive of l class which typically shows only minor activity towards cumene hydroperoxide The classification of GSTs also depends on their responses to substrates and inhibitors Like all GSTs, ... turtle, T s elegans Analysis of kinetic and inhibitory properties characterized these as alpha class GSTs but the two forms showed a variety of distinctive differences The specific activities of both...
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The Rise and Fall of the U.S. Mortgage and Credit Markets: A Comprehensive Analysis of the Meltdown pot
Ngày tải lên :
29/03/2014, 07:20
... matter) is issuing covered bonds These bonds would be issued by banks and collateralized by specific pools of assets, such as mortgages If the bank issuing the covered bonds should default, the holders ... types of loans, offer uninsured deposits, issue different types of securities, invest in different types of securities, and engage in different types of off-balance-sheet activities Banks not ... regime must be designed to address the broad issues of systemic risks Do differences in the size or composition of financial sectors in countries necessitate different regulatory regimes? The recent...
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