nanochemical and nanostructural studies of the brittle failure of alloys
Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
... II The hood domain is mainly built up by residues from the C-terminus and consists of a two-stranded anti-parallel b-sheet composed of b2 and b9 and an a-helix from the C-terminus (Fig 1A) The ... Lys173 interacts with both O6 and N7 (Fig 1C) The 2¢OH of the ribose is hydrogen bonded to the main chain and the side chain of Asp142 (Fig 1C) Both hydroxyl groups of the ribose are involved in ... Asp142, 2¢ and 3¢OH of the ribose and three water molecules with ˚ coordination distances of approximately 2.4 A The phosphate of the GMP is hydrogen bonded to main chain and side chain atoms of amino...
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Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx
... of pantoate [9] Here, we report the results of the structural studies of the pantoate-bound form of the N-terminal domain of E coli PS (nPS) The structure and substrate-binding interactions of ... the A-chain and B-chain of nPS, and in the case of His37, the v1 torsion angle changes from 63.34° to )67.80° and )52.11° for the A-chain and B-chain of nPS, respectively The imidazole ring of ... back to the position of the Fig Superimposition of the A-chain of nPS (green), the B-chain of nPS (cyan), and the substrate-free protein (1IHO.pdb; magenta) The carbon and oxygen atoms of pantoate...
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Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx
... that the work of Lookene et al [27] has already established Of two possible dimeric structures of LPL, the head-tohead and the head-to-tail models, the studies of the chimeric proteins of hepatic ... the C-terminal domain of apoCII interacts with the interface of the N- and C-terminal domains of LPL and part of the lid surface [32] Because the functional importance of LPL’s C-terminal domain ... not the lipase activity and that the normal affinity of these mutants for heparin (Fig 3, Table 1) implies conservation of the overall structure of the WW and WWW mutants – indicate that these...
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Báo cáo khoa học: X-ray crystallography, CD and kinetic studies revealed the essence of the abnormal behaviors of the cytochrome b5 Phe35fiTyr mutant pdf
... [35,36,40,41] The apocyt b5 and apo-Mb have no absorption in the Soret band region because of the lack of the heme prosthetic group For the holo-cyt b5 and holo-Mb, the CD spectra of the Soret band are ... displays the conserved conformation in the structures of the Phe35fiTyr mutant and of the wild-type protein as well as other mutants However, the conformation of the latter is flexible CD spectra of thermal ... b5 and metMb The heme transfer reaction consists of two steps: the first step is the release of the heme from cyt b5, and the second step is the binding of apo-Mb with the heme b [30] Because the...
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Báo cáo khoa học: Antimicrobial and conformational studies of the active and inactive analogues of the protegrin-1 peptide docx
... at the two spatial tips of the molecule, at the N-terminus with Arg1 and in the turn in the presence of Arg7 and Arg9 (see Figs and 4) The shorter analogue, BM-2, was the most flexible of all the ... of the peptide Two hydrophilic regions were located at the two spatial tips of the molecule, at both termini with Arg1 and Arg17, and in the turn in the presence of Arg8 and Arg10 (see Figs and ... on the membrane This may also account for differences in the haemolytic activity of the peptides A better understanding of the mode of action of these peptides is crucial for the development of...
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Báo cáo Y học: Engineering and mechanistic studies of the Arabidopsis FAE1 b-ketoacyl-CoA synthase, FAE1 KCS pot
... substitution of basic histidine for the asparagine resulted in inactive enzyme Taken together, the analysis of the decarboxylation activity and characterization of the mutants of the putative ... mutational studies of chalcone synthase have demonstrated that decarboxylation of malonyl-CoA is independent of acylation of the active site cysteine [24] In these studies, substitution of the active-site ... resulting in the formation of the product The FAE1 KCS mechanism has not been characterized and is known to use malonyl-CoA instead of malonyl-ACP Nonetheless, the mechanism of the fatty acid...
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Báo cáo toán học: "Antioxidant, antimicrobial, and theoretical studies of the thiosemicarbazone derivative Schiff base 2-(2-imino-1-methylimidazolidin-4-ylidene)hydrazinecarbothioamide (IMHC)" potx
... Tautomerization of thione Scheme The synthesis of IMHC Figure Optimized 3D structure of the IMHC Figure The effect of test organism toward synthesized compound Figure The effect of tested fungi toward synthesized ... across the C=N bond The existence of the thione form predominantly in the solid state is demonstrated by the presence of two absorption bands at 1273.7 and 3421 cm−1 belonging to the C=S and NH ... FT-IR spectroscopy The FT-IR spectra provide valuable information regarding the nature of functional group of IMHC The appearance of a broad strong band in the IR spectra of IMHC in 3421 cm–1...
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Báo cáo khoa học: "Clinical review: The implications of experimental and clinical studies of recruitment maneuvers in acute lung injury" pptx
... Finally, large randomized studies not support the use of RMs in patients with ARDS In conclusion, the use of RMs cannot be recommended in the light of current knowledge, and if RMs are used they should ... in the prone than in the supine position, and importantly the benefit was sustained at lower PEEP In other studies other adjuncts to MV were necessary to keep the lung open after RMs [20] Lu and ... suggest that RMs have different effects depending on the type of lung insult and on the use of various combinations of tidal volume and PEEP Whether RMs are necessary to prevent alveolar collapse...
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Báo cáo y học: "Influence of enrollment sequence effect on observed outcomes in the ADDRESS and PROWESS studies of drotrecogin alfa (activated) in patients with severe sepsis" pptx
... report the results of these analyses and additional exploratory analyses of both the PROWESS and ADDRESS databases We discuss the results of these analyses in the context of their implication on the ... the conception and design of the study, in the development and conduct of analyses, and in the clinical trials and data collection WLM, JJ, and DRN participated in the conception and design of ... review of studies examining the independent relationship between hospital or physician volume and clinical outcomes They found that, overall, 71% of all studies of hospital volume and 69% of studies...
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MOLECULAR AND PHYSIOLOGICAL STUDIES OF SALT TOLERANCE IN THE SALT SECRETOR MANGROVE AVICENNIA OFFICINALIS
... acknowledge the support of my entire family for believing in my potential and special thanks to my parents, my brother and my husband for their continuous support and understanding, without them this ... physiological and molecular aspects of salt tolerance in A officinalis The notable contributions of this study include confirmation of the role of AoDHN1 in stress remediation and identification of a ... initiation of erosion along much of the coastline due to the construction of the Kranji Dam, immediately east of the study area, with the mangrove fringe having removed by up to 50m in 2001 These...
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A genealogy of japanese solidarity discourse on philippine history war with america and area studies in the cold war
... impressions of the place: I have met your great ruler Mutsu Hito2 and others of your statesmen, and have been impressed with their progressive spirit, the thoroughness of their knowledge, and the saneness ... discourse in the writing of Philippine and Southeast Asian history Specifically, the second part of the thesis asks: Given the dismissal and even exclusion of Japanese wartime writing in the postwar ... my four and a half years of study at the NUS I want to dedicate this thesis to “Prof Rey” as a part of my “utang,” which I permanently owe him The academic staff of the Department of Southeast...
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Theoretical and experimental studies on the promoting effect of boron on cobalt catalyst used for fischer tropsch synthesis
... characterization, and FTS reactor studies to confirm and understand the effect of boron promotion on the stability of Co catalyst under realistic FTS conditions Figure 1.1 TGA profile showing the evolution of ... combination of Density Functional Theory (DFT) and thermodynamic calculations, careful catalyst characterization, and by realistic reactor studies Using the detailed understanding of the dominant ... al., 2010) The objective of this thesis is therefore to first understand the mechanism responsible for the deactivation of Co catalyst under realistic FTS conditions The deactivation of Co catalysts...
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Experimental and numerical studies on the viscoelastic behavior of living cells
... least 1) the viscoelasticity of the cortex, cytoplasm and the nucleus, and 2) static surface tension and the active forces of the cytoskeleton Determination of the relative contribution of these ... methodology and theoretical model put forward in this thesis will contribute to a more accurate evaluation of the viscoelastic properties of cells and better understanding of the biological response of ... aspects of the mechanical behaviors of the cells Because of the heterogeneity and viscoelasticity of cells, the measured mechanical properties are very dependent on the techniques For example, the...
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Structural, electrical and optical studies on the effects of rapid thermal processing on silicon germanium carbon films
... strain The band offset is shown and it is known as type I straddling alignment (Fig.2.3 (a)) The entire band offset occurs in the valence band while the band offset in the conduction band is small ... electrical, and optical) of as-prepared and rapid thermal processed (oxidation and annealed) Si1−xGex and Si1−x−yGexCy alloys grown by RTCVD The structural properties of the as-prepared and rapid thermal ... presence of strain resulted in the lifting of the degeneracy of the bands of interest (i.e the valence band in compressively strained SiGe on Si and the conduction band in tensile strained Si on...
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Equilibrium and kinetic studies on the liquid liquid extraction and stripping of l phenylalanine via reversed micelles
... amino acid and that the partitioning of the amino acid between the aqueous phase and the micellar phase depends on both the ionic strength and the type of salt used The influence of the total ... into the water pool of the reversed micelles through the channel of the bud Fusion of the interfacial surfactant layer in the neck of the bud occurs, followed by the diffusion of the amino acid-containing ... present in the aqueous phase, the type of surfactant, cosurfactant and organic solvent used, temperature and the properties of the amino acids on the kinetics of extraction and reextraction of amino...
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Báo cáo khoa học: Human telomeric G-quadruplex: thermodynamic and kinetic studies of telomeric quadruplex stability potx
... be determined The thermodynamics and kinetics of the transition of the human telomere quadruplex between the Na+ basket form and the K+ hybrid form was recently described [73] CD and DSC were ... practical problems There are worrisome reports documenting that the lengths of the pre- and posttransition baselines selected and used in data analysis directly affect the values of the thermodynamic ... Additional thermodynamic studies are needed to resolve the discrepancies and to obtain a coherent picture of the thermodynamic profile for quadruplex formation Thermodynamic studies of quadruplex...
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Báo cáo khoa học: Fluorescence quenching and kinetic studies of conformational changes induced by DNA and cAMP binding to cAMP receptor protein from Escherichia coli ppt
... curve The plots of the inverse time constant (kobs) are linear (Fig 9) and the values of koff and the association-rate parameter, kon, listed in Table 3, were determined as the intercept and the ... fractional contributions of the uorescence of the red and blue components from the solute quenching experiments by using the fractional contributions of the short and long lifetimes of the Trp13 residue ... whereas the maximum of the less quenchable component remains unchanged at 338 nm The maxima of the resolved spectra and their relative intensities, measured as the areas under each of the resolved...
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Báo cáo khoa học: Comparative biochemical and functional studies of family I soluble inorganic pyrophosphatases from photosynthetic bacteria potx
... (Table 1) They display, however, greater heterogeneity in the molecular mass of the detected protein band, as is also the case for metal cation dependence, as the sPPase activity of many of these ... regulated by the same factors Analysis of the promoter regions of 3954 Sequence and phylogenetic analysis Knowledge of the N-terminal sequences of the three cyanobacterial sPPases purified and characterized ... salt (MgCl2) and mm Na4PPi (standard assay conditions) The reaction was started by the addition of enzyme, and the PPi released after 10 was determined When the efficiencies of other divalent...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008