n staging of gastric cancer by eus
báo cáo hóa học:" Serum high mobility group box-1 (HMGB1) is closely associated with the clinical and pathologic features of gastric cancer" pptx
... mRNA in human gastrointestinal adenocarcinoma and corresponding non-cancerous mucosa Int J Cancer 1997, 74:1-6 Terry MB, Gaudet MM, Gammon MD: The epidemiology of gastric cancer Semin Radiat Oncol ... on the theory of gastric carcinogenesis and HMGB1 levels were significantly different between normal and high-risk lesions of GC as well as between cancer and noncancer These results are consistent ... activity of gastric cancer J Pathol 2002, 196:163-170 Oue N, Aung PP, Mitani Y, Kuniyasu H, Nakayama H, Yasui W: Genes involved in invasion and metastasis of gastric cancer identified by array-based...
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Báo cáo hóa học: " Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory evidence and clinical significance" pptx
... Co-evolution of tumor cells and their microenvironment in cancer invasions Both of tumor cells and their microenvironment are involved in cancer invasions Invasion is the first observable step of cancer ... front may cooperate in invasion by constantly changing the local microenvironment In linear pattern, a few coordinated “pioneering cancer cells” form deep penetrating invasion tunnels along a ... interactions between cancer cells and their microenvironment In the Washing pattern, successive waves of cancer cells may induce progressive conditioning of the microenvironment to facilitate cancer...
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Báo cáo sinh học: " Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival of gastric cancer with peritoneal carcinomatosis: evidence from an " pdf
... evaluation of HIPEC In recent years, increasing number of animal models of PC have been intensively studied, including nude mouse model of gastric cancer PC constructed by implanting human gastric cancer ... murine xenograft PC model of appendiceal mucinous adenocarcinoma constructed by implanting human appendiceal neoplasms into the peritoneal cavity of homozygous nude mice [36]; mouse ovarian cancer ... colon cancer PC model constructed by injecting colon cancer cells into the abdominal cavity of Balb/C mice [29]; rat colon carcinoma PC models constructed through injecting CC531 colon carcinoma...
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Báo cáo sinh học: "Combination immunotherapy and active-specific tumor cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer" pdf
... expansion of antigen-specific T cells in a lymphopenic van den Engel et al Journal of Translational Medicine 2011, 9:140 http://www.translational-medicine.com/content/9/1/140 environment and (ii) ... vaccination augments anti -cancer immunity in a mouse model of gastric cancer Journal of Translational Medicine 2011 9:140 Submit your next manuscript to BioMed Central and take full advantage of: ... Translational Medicine 2011, 9:140 http://www.translational-medicine.com/content/9/1/140 A Tumor Reconstitution, Vaccination injection vaccination Day - -1 Page of 14 Vaccination 14 Vaccination...
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báo cáo hóa học:" Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival of gastric cancer with peritoneal carcinomatosis: evidence from an experimental study" doc
... evaluation of HIPEC In recent years, increasing number of animal models of PC have been intensively studied, including nude mouse model of gastric cancer PC constructed by implanting human gastric cancer ... murine xenograft PC model of appendiceal mucinous adenocarcinoma constructed by implanting human appendiceal neoplasms into the peritoneal cavity of homozygous nude mice [36]; mouse ovarian cancer ... colon cancer PC model constructed by injecting colon cancer cells into the abdominal cavity of Balb/C mice [29]; rat colon carcinoma PC models constructed through injecting CC531 colon carcinoma...
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MANAGEMENT OF GASTRIC CANCER potx
... and can appear as circumscribed wall thickening with intense focal enhancement or intense enhancement only, without wall thickening or circumscribed wall thickening with intense enhancement of ... could be shown not only MR findings of gastric wall invasion but also perigastric lymph node involvement in the gastric carcinoma MRI is useful for staging of T staging of gastric cancer, whereas ... multiplanar reconstruction) in the evaluation of gastric cancer: a comparison with conventional endoscopy, EUS and histopathology Gastrointest Endosc 59: 619-626 16 Management of Gastric Cancer...
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Báo cáo khoa học: "Effects of propranolol in combination with radiation on apoptosis and survival of gastric cancer cells in vitro" ppsx
... irradiation sensitizer in gastric cancer therapy Guidelines of the NCCN on gastric cancer Figure Quantification of mRNA expression of different genes Analysis of mRNA expression of COX-2, VEGF and EGFR ... Zerumbone abolishes NF-κB and InBa kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion Oncogene 2005, ... Role of cyclooxygenase inhibitors in combination with radiation therapy in lung cancer Clin Lung Cancer 2003, 4:356-365 17 Terakado N, Shintani S, Yano J, Chunnan L, Mihara M, Nakashiro K, Hamakawa...
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báo cáo khoa học: " The function and mechanism of COX-2 in angiogenesis of gastric cancer cells" pdf
... down-regulation of COX-2 might inhibit the malignant growth of SGC7901 cells in vivo Down-regulation of COX-2 inhibited angiogenesis of gastric cancer cells As shown in Figure 3, the number of ... Hong L, Zhao Y, Han Y, Guo W, Jin H, Qiao T, Che Z, Fan D: Mechanisms of growth arrest by zinc ribbon domain-containing in gastric cancer cells Carcinogenesis 2007, 28(8):1622-8 Hong L, Wang ... antiproliferative and antiangiogenic activity in several types of human cancer However, the mechanism of COX-2 in angiogenesis remains unclear In this study, the data showed that down-regulation of COX-2...
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báo cáo khoa học: " Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells" docx
... Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells Journal of Experimental & Clinical Cancer Research 2011 30:55 Conclusions In conclusion, down-regulation ... colon formation was assessed As shown in Figure 1C, down-regulation of miR-27a significantly inhibited the number of colonies formed by gastric cancer cells Tumorigenesis was found profoundly ... http://www.jeccr.com/content/30/1/55 Page of Figure Effect of miR-27a on ADR intracellular accumulation and releasing of MKN45 cells A, Fluorescence intensity analysis of intracellular ADR in cells; B, ADR releasing...
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báo cáo khoa học: "Recombinant immunotoxin anti-c-Met/PE38KDEL inhibits proliferation and promotes apoptosis of gastric cancer cells" docx
... XJ, Feng ZQ, Zhu J, Tang qi, Liu zheng: Construction, expression and purification of an immunotoxin containing a human anti-c-Met singlechain antibody fused to PE38KDEL Acta Univ Med Nanjing 2009, ... Nanjing Medical University, Nanjing, 210029, PR China 2Department of Pathology, Nanjing Medical University, Nanjing, 210029, PR China Wei et al Journal of Experimental & Clinical Cancer Research ... Acknowledgements and Funding This study was funded by nature science founation of jiangsu province (BK2008483) Author details Department of Gastroenterology, The Second Affiliated Hospital of Nanjing Medical...
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báo cáo khoa học: "BRCAA1 monoclonal antibody conjugated fluorescent magnetic nanoparticles for in vivo targeted magnetofluorescent imaging of gastric cancer" ppsx
... al Journal of Nanobiotechnology 2011, 9:23 http://www.jnanobiotechnology.com/content/9/1/23 Author details Department of Bio-nano Science and Engineering, National Key Laboratory of Nano/Micro ... in vivo targeted magnetofluorescent imaging of gastric cancer Journal of Nanobiotechnology 2011 9:23 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online ... measurement of FMNPs-anti-BRCAA1 antibody Total concentration of the anti-BRCAA1 antibody (ng/μL) The concentration of anti-BRCAA1 antibody in residual reaction mixture (ng/μL) Coupling rate (%)...
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Molecular signatures of gastric cancer an integrated approach to molecular cytogenetics, whole genome copy number and transcriptome profiles
... expression profiling 13.2 Expression of breakpoint genes by immunohistochemical staining v Table of contents 14 Precise determination of translocation breakpoints by 295 arraypainting 14.1 Chromosome ... demonstrated by recent discoveries of recurrent translocations in human prostate adenocarcinomas4 and non-small cell lung cancer5 These signature translocations impute shared oncogenic mechanisms ... Wellcome Trust Sanger Institute at Hinxton, Cambridge: Dr Nigel Carter, Ng Bee Ling, Fu Beiyuan, Yang Fengtang, Susan Gribble and Elena Elenor The month-long training had been an eye-opener I treasure...
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Genomic and transcriptomic analysis of gastric cancer systematic studies on transcriptional bias in aneuploidy and gene coexpression meta network
... Distinctive Patterns of Gene Expression in Premalignant Gastric Mucosa and Gastric Cancer, Cancer Res 63;2003:2569-2577 39 Chen X, et al Variation in Gene Expression Patterns in Human Gastric Cancers, ... definition of dominance in the current implementation of WAVES results in an underestimation of the regions deemed significant 20 Figure 2.2: Definition of dominance causes underestimation of ... profiles of cancers First, the existence of transcriptional bias in the regions of aneuploidy is addressed by showing pervasive imprinting of aneuploidy on the cancer transcriptome by reconstructing...
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Báo cáo y học: "Anti-tumorigenic and Pro-apoptotic effects of CKBM on gastric cancer growth in n" potx
... herbs and yeast) on the growth of human gastric cancer using a unique subcutaneous implantation model of gastric cancer tissue In this connection, CKBM was given at different doses to investigate ... Schisandra chinensis has been shown to reduce prostate cancer cell growth and induce apoptosis by inhibiting androgen receptor expression [1] Besides, soybeans contain various anti-carcinogenic ... prior joining the company He had been the founding Editor and Editor-in-Chief of Biological Signals and Biological Signals and Receptors, Adjunct Professor of University of Toronto and is Honorary...
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Báo cáo khoa học: "A case of virilization induced by a Krukenberg tumor from gastric cancer" docx
... consistent with the diagnosis of gastric adenocarcinoma The neuroendocrine markers CD56, chromogranin and synaptophysin were negative ruling out a neuroendocrine subpopulation of the tumor In addition, ... Mansi J, Nicolson M, Hickish T, Nicolson V, Nash A, Sacks N, Ford H, : A phase II study in advanced gastro-esophageal cancer using epirubicin and cisplatin in combination with continuous infusion ... Levin HS, Migeon CJ, Martin LG: Gonadotropin-dependent Krukenberg tumor causing virilization during pregnancy J Clin Endocrinol Metab 1968, 28:198-214 SPADONI LR, LINDBERG MC, MOTTET NK, HERRMANN...
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Tài liệu Báo cáo khoa học: Different modes of dipeptidyl peptidase IV (CD26) inhibition by oligopeptides derived from the N-terminus of HIV-1 Tat indicate at least two inhibitor binding sites doc
... mechanisms of Tat–DP IV interactions and thereby contributing to the understanding of the functional effects mediated by signal transduction processes induced by Tat, kinetic investigations mainly of ... application of simulated annealing techniques without applying a huge water box surrounding the whole enzyme– ligand complex and periodic boundary conditions Two independent simulated annealing runs ... single amino acid substitutions at certain positions of the parent structure alter the mode of inhibition indicating binding of the peptide to another binding site In addition to differences in...
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Overview of Trastuzumab’s Utility for Gastric Cancer pdf
... advanced GC as monotherapy, maintenance treatment after doublet or triplet regimens, in continuation beyond progression, and in combination with second line therapy; as well, in curative treatment ... National Cancer Research Institute of the United Kingdom Capecitabine and oxaliplatin for advanced esophagogastric cancer N Engl J Med 2008; 358:36-46 Van Cutsen E, Moiseyenko VM, Tjulandin S, ... dimerization followed by transactivation of the TK portion of the dimer Phosphorylation allows recruitment and activation of downstream proteins, and the signaling cascade is initiated Given HER2 functions...
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Báo cáo khoa học: Inhibition of PI3K/Akt partially leads to the inhibition of PrPC-induced drug resistance in gastric cancer cells pdf
... Overexpression and significance of prion protein in gastric cancer and multidrug-resistant gastric carcinoma cell line SGC7901/ADR Int J Cancer 113, 213–220 Liang J, Pan YL, Ning XX, Sun LJ, Lan M, Hong ... construction Gene PrP C PrPC RNAi1 PrPC RNAi2 Akt RNAi MDR-1 MDR-1 promoter Direction Sequence (5¢- to 3¢) Sense Antisense Sense Antisense Sense Antisense Sense Antisense Sense Antisense Sense ... determined using flow cytometry with an excitation wavelength of 488 nm and an emission wavelength of 575 nm (A) Fluorescence intensity analysis of intracellular adriamycin in gastric cancer cells...
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Báo cáo khoa học: Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris ppt
... removed by the yeast KEX2 protease (Pichia pastoris Expression Kit manual, Invitrogen, Groningen, the Netherlands) Cloning of elan and trappin-2 cDNA into pPIC9 Using the trappin-2 cDNA cloned into ... Thespecicactivityofrecombinantelanandtrappin-2(ratio of active inhibitor vs protein content) was found to be about 95% as inferred from active site titration experiments and determinationoftheproteincontentbytheBradfordmethod ... given in Table Measurement of kass and kdiss for the interaction of rec-elan or rec-trappin-2 with HNE and PR3 Linear inhibition curves were obtained when reacting increasing amounts of each inhibitor...
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