... [1,2] Other adultstemcells include neural stemcells (NSCs) [3], and the mesenchymal stemcells (MSCs) that give rise to osteoblasts, chondrocytes, adipocytes, and skeletal and smooth muscle ... marrow stemcells (hBMSC), marrow-isolated adult multilineage inducible (MIAMI) cells, and pre-MSCs), umbilical cord blood (unrestricted somatic stemcells (USSCs)), placenta, muscle, and other ... neural stemcells Science 2000, 287:1433-1438 Prockop D: Marrow stromal cells as stemcells for nonhematopoietic tissues Science 1997, 276:71-74 Smith AG: Embryo-derived stem cells: of mice and...
... growth factor stimulated and not stimulated cells was calculated and compared for different periods before and after intervention Stem- Kine mobilizes CD34 and CD133 Cells Statistics Differences ... human stemcellsStemCells Dev 2006, 15(1):118-23 77 Shytle RD, Ehrhart J, Tan J, Vila J, Cole M, Sanberg CD, Sanberg PR, Bickford PC: Oxidative stress of neural, hematopoietic, andstem cells: ... infarction [59,60] and stroke [61], are associated with upregulated levels of these cells Given the possibility that both hematopoietic stemcellsand EPC may serve as endogenous “repair cells , we sought...
... Therefore, the exogenous stem/ progenitor cells, such as embryonic stemcells (ESCs), bone marrowor fat-derived mesenchymal stemcells (MSCs), and recently amniotic fluid stem/ progenitor cells, could be ... fluid stemcells can integrate and differentiate into epithelial lung lineages StemCells 2008, 26:2902-2911 Takahashi K, Yamanaka S: Induction of pluripotent stemcells from mouse embryonic andadult ... population of endothelial cells resistant to bronchiolar and alveolar damages and which is capable of giving rise, not only to Clara cells, but also to type I and type II alveolar cells in vitro was...
... include cloned cells, embryonic or fetal stem cells, or adultstemcells Although each of these sources of stemcells has potential biological advantages and disadvantages, ethical and legal concerns ... cloning (1–4) and the use of embryonic and fetal stemcells (5) Adultstemcells might provide medical solutions that avoid the ethical and legal problems of cloning and fetal stem cell approaches ... emerging on adultstemcells Much of the public attention and debate has been focused on the possibility that adultstemcells may be used as a substitute for human embryonic stemcells or as...
... human biopsies and post-mortem tissues [35] It is hypothesized that newborn neuronal cells in the adult brain originate from residual stemcells The existence of stemcells in the adult brain suggests ... self-repair and that newborn neuronal cells may contribute to the functioning, and physioand pathology of the CNS [36] However, adult NSCs remain elusive cellsand to be unequivocally identified and ... neural progenitor andstemcells [39] Self-renewing multipotent neural progenitor andstemcells have been isolated and characterized in vitro, from various regions of the adult mammalian CNS,...
... engineering and regeneration [134] Mesenchymal stemcells versus embryonic stemcells Embryonic stem (ES) cells are derived from the inner cell mass of the embryonic blastocyst These cells can ... ‘bone marrow stem cell’, which is often used for either hematopoietic or mesenchymal stem cells, the central nervous system stem cell, the hepatic stem cell, etc.? If many stemcells are found ... supports the survival and differentiation of stemcells These complementary approaches have been used to compare different groups of stemcells in order to identify core stem genes and to examine...
... Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy J Cell Mol Med 2004, 8:301-316 31 Tuan RS, Boland G, Tuli R: Adult mesenchymal stemcells ... markers and pulse–chase techniques can be used to label stemcells [79] In other systems, asymmetric division has been shown to be integral to stem cell self-renewal This unique property of stemcells ... multipotent adipose-derived stemcellsStemCells 2006, 24:2412-2419 Kleber M, Sommer L: Wnt signaling and the regulation of stem cell function Curr Opin Cell Biol 2004, 16:681-687 Boland GM, Perkins G,...
... searchers have transplanted the bone marrow stemcells into the necrotic femoral heads, and results show bone marrow stemcells can remove vascular lesions and promote angiogenesis in necrotic femoral ... [19-21] Recently, in order to improve the efficacy of stem cell transplantation, committed stemcells are isolated and purified, and single lineage stem cell transplantation is then performed Deng ... expressed in injured tissues play important roles (2) Stemcells circulate among tissues, andstemcells migrate to the injured tissues once injury occurs Stem cell homing is a complicated process in...
... adult human mesenchymal stemcells Science 284, 143–147 Porada CD, Zanjani ED & Almeida-Porad G (2006) Adult mesenchymal stem cells: a pluripotent population with multiple applications Curr Stem ... mesenchymal stemcellsand mononuclear cellsStemCells 25, 1166–1177 Li L, Zhang S, Zhang Y, Yu B, Xu Y & Guan Z (2009) Paracrine action mediates the antifibrotic effect of transplanted mesenchymal stem ... presence and absence of IL-10 *P < 0.05 and **P < 0.01 versus Cont group (D) Representative western blots for collagen I and III in the presence and absence of 0.1 lM angiotensin II and IL-10...
... ES cellsand in human hematopoietic progenitor cells Discussion B Fig Transcription of LCR hypersensitive site in undifferentiated murine embryonic stemcellsand in human CD 133+ bone marrow cells ... Levings et al density of 105 cells well)1 The cells were passaged again and reseeded on day On days 0, 5, 8, 10 and 12, cells were collected and subjected to RT-PCR and ⁄ or ChIP analysis Globin ... structure modifications and factor recruitment at the murine b-globin locus in uninduced embryonic stemcells (day 0), as well as that of primitive and definitive erythroid cells (days and 12, respectively)...
... PROJECT OVERVIEW AND DEFINITIONS ADULTSTEMCELLS 19 EMBRYONIC STEMCELLS 31 OPPORTUNITIES FOR AND BARRIERS TO PROGRESS IN STEM CELL RESEARCH FOR REGENERATIVE MEDICINE 41 FINDINGS AND RECOMMENDATIONS ... between adultand embryonic stemcellsand among adultstemcells found in different types of tissue The implications of these biological differences for therapeutic uses are not yet clear, and additional ... embryonic andadult human stemcells will be required to most efficiently advance the scientific and therapeutic potential of regenerative medicine Research on both adultand embryonic human stem cells...
... Properties and Potential Benefits of Human Embryonic StemCellsand Wharton’s Jelly StemCells 136 Chui-Yee Fong, Kalamegam Gauthaman, and Ariff Bongso 14 Amniotic Fluid and Placenta StemCells 150 ... Atala 15 AdultStemCells in the Human Endometrium 160 ´, ´n Caroline E Gargett, Irene Cervello Sonya Hubbard, and Carlos Simo 16 Stem Cell Populations in Adult Bone Marrow: Phenotypes and Biological ... human male germ cells from bone marrow stemcells Soc Reprod Fertil Suppl 2007; 63:69–76 36 Takahashi K, Yamanaka S Induction of pluripotent stemcells from mouse embryonic andadult fibroblast...
... mesenchymal stemcells (AT-MSCs) differentiate into hepatocyte-like cells upon treatment with hepatocyte growth factor (HGF), oncostatin M and dimethyl sulfoxide [13] These cells expressed albumin and ... mesenchymal stemcells of fetal or maternal origin from human placenta StemCells 22, 1338–1345 Bieback K, Kern S, Kluter H & Eichler H (2004) Critical parameters for the isolation of mesenchymal stemcells ... Huang CT, Tsai CC, Shen EY & Chiu WT (2005) Isolation and characterization of neurogenic mesenchymal stemcells in human scalp tissue StemCells 23, 1012–1020 In’t Anker PS, Scherjon SA, Kleijburg-van...
... (slowly dividing astroglial cellsand the bona fide adult neural stem cells) , type C cells (transit-amplifying cells derived from asymmetric division of Type B cells) , type A cells (immature neuroblasts ... history and the most advanced discoveries in neural stemcells This book provides the strategies and challenges of utilizing neural stemcells for therapy of neurological disorders and brain and ... Bian and Tao Sun Part Neural StemCellsand Therapy 257 Chapter 13 Neural Stem/ Progenitor Cell Clones as Models for Neural Development and Transplantation 259 Hedong Li, He Zhao, Xiaoqiong Shu and...
... novel circulating human embryonic blood stemcells Blood 96, 1740 - 1747 IItskovitz - Eldor, J and et al (2000).; Differentiation of human embryonic stemcells into embryoid bodies comprising the ... human pancreatic cell line in vitro and in vivo Mol Endocrinol 15, 476 - 483 Dzierzak, E et al (1998); Embryonic beginnings of definitive hematopoietic stemcells Ann N Y Acad Sci 872, 256 - 262 ... 814 - 822 Jones, G M., et al (2000); Human embryonic stemcells technology Semin Reprod Med 18, 219 - 223 Orlic D et al (2001); Bone marrow cells regenerate infarcted myocardium nature 410, 701...
... Studying StemCellsand Progenitors Jane E Aubin, Fina Liu, and G Antonio Candeliere 403 30 Nonradioactive Labeling and Detection of mRNAs Hybridized onto Nucleic Acid cDNA Arrays Thorsten Hoevel and ... (ES cells to inject andcells to pellet for DNA) into the microfuge and spin for at 110g To make sure trypsin is removed, aspirate the supernatant and add mL M2 to the cells for injection and ... something for both experts and novices alike, that it will serve as a launching point for further developments in stem cells, and that we will all-too-soon wish to expand and update it with other...
... Alvarez-Buylla, A and Lois, C (1995) Neuronal stemcells in the brain of adult vertebrates StemCells 13, 263–272 Production and Analysis of Neurospheres 27 Gage, F., Ray, J and Fisher, L (1995) ... “Isolation and Culture of Neural StemCells introduces the reader to different sources of stem/ progenitor cellsand provides a wide range of conditions for their selection, nourishment, growth and ... “Utilization/Characterization of Neural StemCells in vivo,” is a collection of techniques to identify and characterize endogenous stemcells as well as exogenous stemcells after transplantation into...
... of stemcells in repair of liver injuries Several types of stem cells, such as embryonic stem (ES) cells, induced pluripotent stem (iPS) cells, haematopoietic stem cells, and mesenchymal stem cells, ... liver stem/ progenitor cells exist in normal adult liver Recently, we and others have successfully identied oval cellsandadult liver stem/ progenitor cells Here, we describe the identication and ... formation from stem cells; (4) Liver stemcellsand hepatocarcinogenesis; and (5) Application of liver stemcells for cell therapy All these current topics shed light on stem cell technology...
... latency, threshold and amplitude of electromyogram and number, thickness, circumference and area of myelinated nerve fibers derived from rabbits with and without facial nerve injury and repair using ... neural stemcells can migrate, differentiate, and integrate after intravenous transplantation in adult rats with transient forebrain ischemia Neurosci Lett 2003, 343:129-133 Evans GR, Brandt K, ... made use of HA-collagen composite scaffold, NSCs and NT-3 as a nerve guide, effecter cellsand neurotrophic/neuroprotective factor, respectively, and implanted the conduit of NSCsimplanted NT-3-supplemetned...
... stemcells transdifferentiated in muscle cells in vitro CD34+ stemcells transdifferentiated in muscle cells in vitro CD34+ stemcells that transdifferentiated in dystrophin producer muscle cells ... syncytium CD34+ stemcellsand muscle cells division was also observed (data not shown) Dystrophin IF IF assay was performed after 15 days in culture Co-cultures of CD34+ stemcellsand DMD myoblasts ... (figure 4) This result suggests that the fusion of stemcellsand muscle cells was sufficient to induce the stemcells nuclei to express muscle cells proteins, restoring the absent dystrophin expression...