molecular mechanisms biological effects and therapeutic strategies of protection
Báo cáo y học: " A review of bronchiolitis obliterans syndrome and therapeutic strategies." doc
... of baseline & FEF25-75% > 75% of baseline 0-p* FEV1 81-90% of baseline &/or FEF25-75% ≤ 75% of baseline FEV1 66-80% of baseline FEV1 51-65% of baseline FEV1 ≤ 50% of baseline *0-p = potential ... article as: Hayes: A review of bronchiolitis obliterans syndrome and therapeutic strategies Journal of Cardiothoracic Surgery 2011 6:92 • Inclusion in PubMed, CAS, Scopus and Google Scholar • Research ... Figure Representative histopathology of obliterative bronchiolitis with inflammation and fibrosis of the airway with sparing of the surrounding alveoli (Hematoxylin and Eosin stain) Acute rejection...
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MECHANISMS OF HEXOSAMINE-INDUCED CHOLESTEROL ACCUMULATION AND THERAPEUTIC ACTIONS OF CHROMIUM
... rise above 140 mg/dL The focus of this thesis is to understand the molecular mechanisms of insulin-mediated glucose transport into adipose tissue and skeletal muscle and how this process becomes ... the Food and Nutrition Board of the Institute of Medicine of the National Academy of Sciences, 34 the adequate intake of chromium is set to 30 µg/d (243) Given the known absorption of chromium ... caloric intake and/ or obesity currently remain the largest predisposing risk factors for the development of type diabetes Discerning the cellular and molecular mechanisms responsible and amendable...
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Development of a crosslinkable biomimetic collagen for mimicry of molecular architecture, biological activity and applications
... template-assembly approach requires a complex and carefully planned protocol of orthogonal protection and deprotection strategies to ensure proper coupling and parallel growth of several peptide chains onto ... inhibition of Hep3B and L929 cell adhesion to collagen Cell adhesion to native and denatured collagen and PT-assembled collagen-mimetic peptides Cytoskeletal organization and focal adhesion immunofluorescence ... ε-amino group of a protein-bound lysine (K donor group) results in the formation of intermolecular isopeptide ε-(γ-glutamyl)lysine crosslink (Lorand and Graham, 2003; Esposito and Caputo, 2004)...
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Báo cáo y học: "Lifetime health effects and medical costs of integrated stroke services - a non-randomized controlled cluster-trial based life table approach"
... Reimer W: Costs of stroke and stroke services: Determinants of patient costs and a comparison of costs of regular care and care organised in stroke services Cost Effectiveness and Resource Allocation ... Selection of outcome measures The economic evaluation compares lifetime health effects and costs of the stroke service as compared to usual stroke care Health effects Lifetime health effects were ... patient and each place of Page of 10 residence (hospital, nursing home, revalidation centre and home) at which the patient stayed during this period, weighted by the length of stay Costs of care...
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Evaluation of the Effects and the Programming of ‘Water Conservation Plan’ (WCP) for Total Water Resources Management in Tokyo
... (rooftop of Sumida-ku Ward Office as catchment area) and communal RWH called ‘rojison’ - 190 - Journal of Water and Environment Technology, Vol 9, No.2, 2011 From the interviews with Sumida-ku officers, ... promote sales of SWT devices □ Coincidence of TMG's request for the development of SWT devices to the makers with strategies of makers out of Tokyo Metropolis □ Cost consciousness of industrial ... policy makers and end-users) Journal of Water and Environment Technology, Vol 9, No.2, 2011 Mandatory Scheme The introduction of WWR and cumulative charging system are considered as mandatory schemes,...
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Diagnostic and Therapeutic Problems of Pulmonary Tuberculosis in Elderly Patients doc
... frequency of liver disease, suggesting the influence of alcoholism These results correspond to those of Alvarez et al (6) and Van den Brande (15) but contrast with those of Katz et al (17) and Umeki ... the importance of sputum AFB smear/ culture for the diagnosis of TB in the elderly A positive sputum AFB smear was obtained in 57.1% of elderly and in 57.5 % of young TB patients, and a positive ... as well as the young, and experienced higher frequencies of adverse reactions The most frequent side effects were drug-induced hepatitis and skin side effects The incidence of reported anti-TB...
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Báo cáo khoa học: Differing molecular mechanisms appear to underlie early toxicity of prefibrillar HypF-N aggregates to different cell types potx
... aggregates and cells, and the response of cells to the presence of aggregates [14,31] According to our previous data, the differing extent of alterations in ROS and free Ca2+ in IMR90 and Hend ... lack of LDH release from both Hend and IMR90 cells exposed to aggregates Mechanisms of apoptotic death in exposed cells Fig Time course of ATP levels in exposed cells and determination of MTP ... by later activation of caspase In IMR90 cells only moderate activation of caspase was found as a consequence of the modest activation of caspase and the lack of activation of caspase (Fig 7A)...
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Báo cáo hóa học: "Future research and therapeutic applications of human stem cells: general, regulatory, and bioethical aspects" ppt
... safety and efficacy of cell therapy products The greater the understanding of the biology of stem cell self-renewal and differentiation, the more precise the evaluation and prediction of potential ... Advances in identification of the optimal characteristics of the matrix and an increased understanding of interactions between cells and biomaterials will condition development of future cell therapy ... wide range of development of new drugs and new procedures for the treatment of a great number of human diseases At least 5-10 years will elapse until these products, not therapeutic yet and under...
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Báo cáo sinh học: "The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer’s disease" pdf
... Care and Use Committee of UCI and were in accordance with the guidelines of the National Institutes of Health Page of 15 viruses was confirmed by RT-PCR and restriction/ sequence analysis of the ... surface of VLP in a repetitive and ordered array Such organization of the epitope may induce T cell-independent B cell activation and production of anti-Ab antibodies of IgM isotype On the other hand, ... analyses and interpretation of data and statistical analysis She helped to draft the manuscript RC participated in preparation of chimeric viruses, purification of viral proteins and performing of...
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Báo cáo hóa học: " Cytotoxic effects and the mechanism of three types of magnetic nanoparticles on human hepatoma BEL-7402 cells" ppt
... model specimen for cytotoxicity assessment, and the aims were to evaluate the cytotoxicity of Fe3O4, OA-Fe3O4, and C-Fe and to elucidate the mechanisms of their cytotoxicities MNPs internalization ... trend Results and discussion MNPs influence on the cell cycle MNPs uptake by human hepatoma BEL-7402 cells The effects of various concentrations (0.05, 0.1, and mg/mL) of the three kinds of MNPs on ... trends shown in WST-1 assay The mechanisms of cytotoxic effects of MNPs on BEL-7402 cells may be implemented through cell cycle arrest and inducing apoptosis Assay of mitochondria-dependent apoptosis...
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Báo cáo toán học: "Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells" ppsx
... in a broad range of neurological diseases and disorders (fig 1) The contribution and significance of this modulation to the etiology and pathogenesis of neurological diseases and disorders remain ... degenerating regions of the CNS [65] Some of the data observed by mean of immunohistochemistry for cell cycle proteins and BrdU labeling in the brains of AD patients and in animal models of the disease, ... strokes and drugs treatments affect the permeability of the BBB and cerebral flow [66-68] Some of the data observed by mean of BrdU labeling in animal models of neurological diseases and after...
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Báo cáo khoa học: "Clinical features and therapeutic management of patients admitted to Italian acute hospital psychiatric units: the PERSEO (psychiatric emergency study and epidemiology) survey" pot
... schizophrenics) and 67–75% among outpatients, with 45 and 28% of combination therapies in in- and outpatients being reported, respectively [28-30] The rates of prescription of conventional and atypical ... observed: benzodiazepines (69% of FPA patients; 69% of non-FPA patients), atypical (in 51 and 53% of patients respectively) and conventional antipsychotics (in 38 and 46% of patients respectively) ... the risk of adverse effects, drug interactions, non-compliance, and medication errors [36] http://www.annals-general-psychiatry.com/content/6/1/29 data and to the writing and review of this paper...
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báo cáo khoa học: " Brain metastases from solid tumors: disease outcome according to type of treatment and therapeutic resources of the treating center" pptx
... sex, primary tumor, date of initial diagnosis of primary cancer, date of radiographic diagnosis of BMs, number and location of BMs, neurologic symptoms, presence/absence of extracranial disease, ... patients, the lack of technical resources may influence the therapeutic decision of the treating physician In fact, in clinical practice, the treatment of BMs is often planned on the basis of the resources ... according to type of treatment and therapeutic resources of the treating center Journal of Experimental & Clinical Cancer Research 2011 30:10 Submit your next manuscript to BioMed Central and take full...
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Báo cáo y học: "Anti-inflammatory effects and possible mechanism of action of lupeol acetate isolated from Himatanthus drasticus (Mart.) Plumel." ppt
... pre-treatment of mice with LA (12.5 and 25 mg/kg, i.p) significantly reduced the volume (μL) of the edema in the 2nd (31 and 41%), rd (30 and 50%) and 4th (23 and 27%) hours after administration of dextran, ... light/dark cycle and food and water supplied ad libitum The experiments were carried out according to the Guide for the Care and Use of Laboratory Animals of the U.S Department of Health and Human Services ... edema and substantial leukocyte migration, mediated by histamine and serotonin in the initial phase of the inflammatory process, and by prostaglandin and bradykinin in later stages On the other hand,...
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employee turnover and retention strategies of small and midium enterprise service businesses in hanoi
... perception of the existence of fair treatment in the workplace This typically consists of such factors as fairness in the selection of employees, evaluation of performance and distribution of rewards and ... between inputs and outputs are learned during the process of socialization and through the comparison with inputs and outcomes of others” To further establish the causes of perceived and actual inequity ... employees of SMEs service businesses Table 4.4 Age of employees of SMEs service businesses 61 Chart 4.4 Age of employees of SMEs service businesses Table 4.5 Qualification of employees of SMEs...
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Buildng business and development strategies of Song Da 5 joint stock company - period 2012 - 2017 strategic vision to 2020
... revenue targets, profit Song Da 2008, 2009, 2010, 2011 and the first six months of 2012 Looking at the chart of revenue and profit targets of the Song Da 5, we see that in 2010 and 2011 the company ... staffs of the group Product No brand name Brand name is Brand name is No brand name quality, brand within the still weak still weak within name of the market the market company Capacity of Weak ... high prices of raw materials to share the profits of the industry The determinants of supplier power is expressed through: - 13 The level of concentration of suppliers The power of suppliers...
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tóm tắt luận án study on the biological characteristics and induced spawning of spotted scat
... Quantity of red blood cell and leukocyte, volume of red blood cell and ratio of leukocyte/red blood cellin different stages of gonad development Quantity of Ratio of Quantity of red Volume of Stage of ... weight 3.12) of fish and length/height of fish 3.2.2.2 The relationship between stage of gonad development to weight of liver/weight of fish and weight of gonad/weight of liver of male spotted ... different stages of gonad development of the male spotted cat, the significant differences of the ratio of weight of liver/weight of fish, and ratio of weight of gonad/weight of liver were not...
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Host viral interactions host factors in coronavirus replication and coronaviral strategies of immune evasion
... the 5’- and 3’ UTR, and TRS of leader (TRS-L) and each ORF (TRS-B), and this is mediated by protein-RNA and protein-protein interactions comprising of both viral and cellular proteins Many of the ... INTERACTION (II): CHARACTERISATION OF HOST ANTIVIRAL MECHANISMS AGAINST CORONAVIRUS INFECTION AND CORONAVIRAL STRATEGIES OF IMMUNE EVASION 4.1 CHARACTERIZATION OF HOST ANTIVIRAL MECHANISMS AGAINST CORONAVIRUS ... in the presence of poly (I:C) stimulation Figure 4-7: The effects of transient expression of RIG-I, MDA5, MAVS and IRF35D on IBV replication Figure 4-8: Over-expression of RIG-I and MDA5 reduced...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008