microvascular dysfunction is the root cause of inflammatory organ dysfunction
Báo cáo y học: "Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis" pdf
... assisted with all measurements for arthritis GKH was the pathologist who analyzed the tissue sections HP supervised all the work and wrote the majority of the manuscript Acknowledgements This ... Expression of pro -inflammatory factors is similar in Wt and Bid-/- mice following serum transfer The cytokine and chemokine milieu of the joint is necessary for the initiation and the perpetuation of inflammatory ... development of inflammatory arthritis One potential factor that bridges the two apoptotic pathways is the BH3-only protein Bid To this end, we examined the impact of deleting Bid (Bid-/-) on the development...
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Tài liệu Research " The Dissertation Committee for Fang Yin Certifies that this is the approved version of the following dissertation: Business Value of Information Technology in the Internet Economy " doc
... where q is the output, xi is the level of input I, α i is the output elasticity of input I, A is a constant, and where N is the number of inputs The Cobb-Douglas production function is the most ... part of this chapter uses the estimates from regressions using the number of employees as the basis of discussion of the results When conducting cross-sectional analysis, heteroskedasticity is often ... increase the productivity of their operations through holistic digitization of their value chain processes The balance of this chapter is organized as follows: Section 1.2 discusses the sparse...
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Tài liệu Báo cáo khoa học: Rotary F1-ATPase Is the C-terminus of subunit c fixed or mobile? docx
... a major part of the coiled-coil region of c and the complete a-helical C-terminus as held within the top of (ab)3 The rotary axis z was aligned along the main axis of the shaft The ‘bearing’ ... with the torque of 56 pNÆnm The secondary structure of c is shown for the time of ns (the end of initial equilibration), 17 ns (half of turnover), 23 ns (one turnover) and 32 ns (the end of final ... during the last ns of the dynamics In both cases the applied torque caused a complete unfolding of the single-helical portion of c at the level of cR254–cV257 residues, a partial deformation of the...
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What Is the Cognitive Neuroscience of Art… and Why Should We Care? ppt
... be; scientists… provide a test of whether this criterion is fulfilled.”2 Or consider the case of neuroaesthetics This new branch of empirical aesthetics is often defined as the study of the neural ... neuroaesthetics (or aesthetic science in general), then perhaps there is cause for skepticism about the utility of empirical aesthetics to researchers in the humanities But is this all it has to offer? ... monthly honorarium from the Society The editor is responsible for the content of the journal The editor is a member of the Board of Trustees of the Society and serves on the Executive Committee...
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Báo cáo khoa học: "What is the Minimal Set of Fragments that Achieves Maximal Parse Accuracy?" potx
... seen, there may be several distinct derivations that generate the same parse tree The probability of a parse tree T is thus the sum of the probabilities of its distinct derivations Let tid be the ... corpussubtree t is converted into a context-free rule r where the lefthand side of r corresponds to the root label of t and the righthand side of r corresponds to the frontier labels of t Indices link the ... subtree in the derivation d that produces tree T, then the probability of T is given by P(T) = ΣdΠi P(tid) Thus the DOP1 model considers counts of subtrees of a wide range of sizes in computing the...
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Báo cáo hóa học: " The effects of hypertonic fluid administration on the gene expression of inflammatory mediators in circulating leucocytes in patients with septic shock: a preliminary study" pptx
... to make cDNA and then the ratio of the Housekeeper gene to the gene of interest was used Because the housekeeper gene is not affected by the treatment, the Ct and the efficiency of amplification ... population, and the expression of inflammatory mediators is highly variable and not only dependent on the source of sepsis but also on the genetic make up of the host, which defines the immune response ... binding effects [10,11] On the other hand, measuring expression of the inflammatory mediator genes may not reflect the functional activity of the end-protein, because this also depends on translation...
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the engine is the beating heart of the airplane 88 pptx
... encircle the piston and seal the combustion chamber Crankshaft: Attaches to the connecting rods and the propeller The motion of the pistons turns the crankshaft Connecting Rods: Attach the pistons ... with the ignition in the Off position, the mag is hot Can I take off if the oil temperature isn’t in the green? Yes, but check to make sure the engine picks up smoothly as the throttle is advanced ... Compression: The piston moves up, compressing the fuel-air mixture into a small space at the top of the cylinder Exhaust: After the rapidly expanding hot gasses finish moving the piston, the exhaust...
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THE ROOT SYSTEMS OF PLANTS pptx
... conducted about 1867, added the lengths of all the fine roots from each of various plants He found that the total length of roots, that is, the sum of the lengths of all the roots, of one wheat plant ... should the work be repeated now The relative weights of the roots and the stems and the leaves not alone show the large quantity of roots; the total lengths of the roots are even more striking The ... that the roots of a well-established field of clover weighed as much as the total weight of the stems and leaves of the year's crop, and that the weight of roots of an oat crop was 43 per cent of...
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Báo cáo lâm nghiệp: "Morphological and functional variability in the root system of Quercus ilex L. subject to confinement: consequences for afforestation" ppt
... length to the depth of the container and preventing the development of replacement taproots The confining of lateral roots in the container and their downward growth lead to the generation of an orthogeotropic ... (i.e the inverse of hydraulic resistance) is defined as the ratio that measures water movement through the roots relative to an external driving force controlling the water flow The adequacy of the ... morphology and root morphology and topology For the morphological characterisation of shoots and roots and the topological characterisation of roots, 22 seedlings were taken randomly per type of container...
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This is the first version of this article to be made available publicly. docx
... and p(α) is the proportion of genes judged significant Furthermore, the criterion C = FP + FN is minimised by choosing an optimal pair of values of the tuning parameter S0 in the SAM statistic Tusher ... evidence of change by pure chance The distribution of these p-values is a mixture of two components corresponding to the changed genes and the unchanged ones The basic question ‘What proportion of ... Methods Denote the pdf of p-values by f, the proportion unchanged by p0 and the distribution of the p-values corresponding the changed genes by f1 Then the distribution of pvalues may be written...
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báo cáo khoa học: " Is the basal area of maize internodes involved in borer resistance?" docx
... to the area at the base of the internode where the rind tissue is light green or white in contrast to the darker green color of the rest of the internode [23] For accuracy, we have renamed this ... EPS20_Short_LIBRC3 Page of 12 could result in higher resistance by decreasing the size of the larval entry area Nevertheless, the role of this mechanism in other genetic backgrounds, such as in the synthetic ... part of internode = LIBR; I2, upper part of the internode (2 cm up from the LIBR area) structural characteristics of stems as mechanisms of resistance to MBC [5,18] The rind-puncture resistance...
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báo cáo khoa học: " Harm reduction, methadone maintenance treatment and the root causes of health and social inequities: An intersectional lens in the Canadian context" ppt
... interpretation of the data and assisted with the drafting of the manuscript CV assisted in the interpretation of the data and the drafting of the manuscript VJ participated in data analysis and interpretation ... mean these drugs started to pop up all over not because they care for the people, [but because] there is money!” In our study, there was a general cynicism expressed regarding how MMT is being offered ... policies) “can inhibit the capacities of some people” at the same time as they expand the options of others (p.10) [68] Many of the participants in our study described the ways in which their lives have...
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Báo cáo khoa học: " Hospital-acquired sinusitis is a common cause of fever of unknown origin in orotracheally intubated critically ill patients" pptx
... Sinusitis is a frequent cause of FUO in the ICU (in this study it was the sole cause in 16% and a contributing factor in 13% of patients with FUO) • Bacterial colonisation of the sinuses often ... by ultrasound The CT scan remains the radiological gold standard in the diagnosis of sinusitis On the basis of the results of our study we recommend that hospital-acquired sinusitis be considered ... with more than one cause of fever had sinusitis and bronchitis/pneumonia; bother causes of fever included meningitis (not related to sinusitis), phlebitis and deep venous thrombosis abscesses and...
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Báo cáo y học: "Dynamic models of immune responses: what is the ideal level of detail" pptx
... pathogenesis and pathogen time-courses The number of components [7,36] that can be modeled is smaller than in discrete models because of the increase in the number of parameters The state of the variables ... effectively to study the progression of the infections Acknowledgements This opinion is an outcome of the discussions at the workshop organized in June 2008 at the Center for Infectious Disease Dynamics ... compatible with the existing experimental knowledge on the pathogenesis The distribution of the parameter values for each immune component in the model tells us about its role in the pathogenesis Recent...
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Báo cáo y học: "bEstrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly" docx
... have had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis Additional data files The following additional data ... model organisms, is present in our enriched data set In light of the considerable overrepresentation of estrogenregulated genes identified in this study, we next asked whether there was statistically ... deliberately excluded the much larger list of GenAge genes shown to modulate lifespan in animal models, because of obvious orthologue issues Including the full GenAge list gave a figure of 3.6 genes expected...
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Báo cáo y học: "A hidden reservoir of integrative elements is the major source of recently acquired foreign genes and ORFans in archaeal and bacterial genomes" pdf
... unlike the e-value, which changes depending on the size of the database We therefore defined the homology cut-off between two sequences when the bit-score of the BLAST hit was above 30% of the bit-score ... calculated the expected number of ORFans inside CAGs given the total number of ORFs in the genome, the total number of ORFs in CAGs, and the total number of ORFans Because the data had a normal distribution, ... advantage of the availability of a large number of genomes from closely related organisms The general strategy is the following (Figure 1): for different groups of closely related genomes, a dataset of...
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An investigation on the root system of mangroves and its influence on current flow
... aerial roots which arise from the main trunk or lower branches of the Rhizophora genus It is believed that the number of prop roots and the complexity of their structure are response to the intensity ... and Thesis Structure In this study, five research questions can be formulated to reach the objective stated in the previous section These questions form the basis for the structure of this thesis ... currents and the 20° isotherm of seawater in winter (Alongi, 2008) The common C characteristic which they all possess is their tolerance to salt and brackish waters The highest concentrations of mangrove...
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Claudin 1 is the direct target of RUNX3 in gastric epithelial cells
... CLAUDIN-1 IS THE DIRECT TARGET OF RUNX3 IN GASTRIC EPITHELIAL CELLS CHANG TI LING (M.Sc., National University of Malaysia) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF MEDICINE ... carcinogenesis (166) Claudin-23 on the other hand, was found to be down-regulated in the intestinal type of gastric cancer (167) All these reports pointed to the link of the diminished level of claudins ... 1999, the Nomenclature Committee of the Human Genome Organization (HUGO) adopted the use of the term ‘RUNX’ to refer to the genes encoding the runt-related proteins, also an abbreviation for the...
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Virut gamma-herpes gây ung thư (Gamma – Herpes is the cause of cancer) potx
... 1980 có tăng đột ngột khối u KS đàn ông trẻ tuổi kèm theo bắt đầu dịch bệnh AIDS Các nghiên cứu dịch tể cẩn thận chứng minh tăng cao bệnh KS theo bệnh lây truyền đờng tình dục (STD) yếu tố khác ... ngời bệnh Bệnh tăng sinh limphô liên kết nhiễm sắc thể giới tính (XLP-X link lymphoproliferative disease) lần đợc Barr cs (đôi bệnh đợc gọi hội chứng Duncan) phát gia đình sau đợc Purtilo nghiên ... phân tử hoàn toàn kỹ thuật phân tích khác biệt đại diện (RDArepresentational differrence analysis), hoàn toàn khác với phơng pháp chuẩn để phát virut Kỹ thuật RDA cho phép mẫu bệnh phẩm bệnh...
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Báo cáo y học: "Is there a dysfunction in the visual system of depressed patients" pptx
... process visual information [9] A neglected area concerns the contribution of the visual system to the genesis of the circadian rhythms of the organism Especially the direct assessment of retinal ... postulates that there is a disturbance in the homeostatic S procedure of sleep (reflecting the need of the organisation for sleep) c The adrenergic-cholinergic imbalance hypothesis of depression of Janowsky ... there is a specific dysfunction at the level of the pigmentum epithelium or the retina responsible for these findings The present study aimed to investigate the outer part of the visual system of...
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