... withasthma within the context of other predictors With this study a first step is made in investigating predictors of HRQoL while taking other predictors in account Since most studies investigate ... aim of the present study was to further explore predictors of HRQoL ofchildrenwithasthma This study is, to our knowledge, the first study that investigated predictors of HRQoL inchildrenwith ... study is to further explore predictors of HRQoL with the stress-coping model resulting towards a better understanding of HRQoL ofchildrenwithasthmain a general context Method Participants...
... The findings of the current study underline the importance of combining self- and proxy rating, not only in Germany Page of 10 (page number not for citation purposes) Health and Quality of Life ... D: Influence of gender and interleukin-10 deficiency on the inflammatory response during lung infection with Pseudomonas aeruginosa in mice Immunology 2002, 107:297-305 Landgraf JM: Measuring ... centres participating in the Benchmarking Project, which has been described in detail by Stern et al [2] The number ofchildrenof this age who participated in the Benchmarking Project in 2005 was...
... now reaching about 80% With increased survival rates, issues concerning the Quality of Life (QoL) of these children become increasingly relevant This is reflected in the steady rise in studies ... certain items during the second, less intensive year of treatment, might be related to an increasing cumulative dose of corticosteroids This underscores the importance of continuing close monitoring ... counselling of both child and family during the whole of treatment In HR children, reported scores on cognitive functioning were considerable lower than in NHR children, regardless of the use of dexamethasone...
... of individuals at risk of aspiration so in a "silent" manner [7], with no overt physiological signs (e.g coughing, face turning red, uncoordinated breathing) and care-givers may have no warning ... processing and artificial intelligence as discrimination tools, rather than the trained clinical ear In clinical studies, accelerometry has demonstrated moderate agreement with videofluoroscopy in ... time index of the digital recording of the vibration signal Methods Representation of swallowing activity Based on the clinical appeal of cervical auscultation and the recent success of swallowing...
... better quality of life with regard to cognitive and emotional domains Interestingly, treatment-related variables, such as intensity of therapy and presence of medical complications mainly influenced ... be used for Swiss children Finally, there may be some concerns regarding our correlational findings, since the chance of falsely significant results increases with the number of comparisons performed ... association of maternal maladjustment with the emotional domains of HRQOL in the acute phase of treatment Discussion This prospective one year follow-up study inchildren and adolescents with newly...
... measurement of HRQoL, encompassing all three components ofchildren s well-being, is still in its infancy inchildrenwith SCD [11] For example, compared to over 400 studies on HRQoL inchildrenwith ... HRQoL inchildrenwith SCD using a self-report measure and a control group of healthy siblings In general, the HRQoL ofchildrenwith SCD appeared similar to the HRQoL of healthy siblings, with ... and need specific care in the hospital Therefore, we argue for routine monitoring of HRQoL inchildrenwith SCD Incorporating patient reported outcomes of HRQoL in daily clinical practice will...
... Measuring health-related quality of life inchildrenwith cancer living in mainland China: feasibility, reliability and validity of the Chinese mandarin version of PedsQL 4.0 Generic ... The findings support the feasibility, reliability and validity of the Chinese Mandarin version of PedsQL 4.0 Generic Core Scales and 3.0 Cancer Module inchildrenwith cancer living in mainland ... limited information is available to understand the HRQOL ofchildrenwith cancer living in mainland China The objective of this study was to investigate the feasibility, reliability, and validity of...
... now reaching about 80% With increased survival rates, issues concerning the Quality of Life (QoL) of these children become increasingly relevant This is reflected in the steady rise in studies ... certain items during the second, less intensive year of treatment, might be related to an increasing cumulative dose of corticosteroids This underscores the importance of continuing close monitoring ... counselling of both child and family during the whole of treatment In HR children, reported scores on cognitive functioning were considerable lower than in NHR children, regardless of the use of dexamethasone...
... and asthma and allergy-related phenotypes in families ofchildrenwithasthmain an ongoing study of the Genetics ofAsthmain Costa Rica We then attempted to replicate positive findings in Costa ... measured in CAMP) Among Costa Rican childrenwith asthma, homozygosity for the minor allele of each of two Table 1: Baseline Characteristics ofChildrenwithAsthmain Costa Rica and White Childrenwith ... Pairwise1(r2) Linkage DisequilibriumRica and B) CAMP ParFigure ents of Index Childrenin A) Costa Plots for IL12A in Pairwise (r2) Linkage Disequilibrium Plots for IL12A in Parents of Index Childrenin A)...
... SNP in TSLP was associated with reduced odds for AR in boys across the three cohorts ofchildrenwithasthma The Genetics ofAsthmain Costa Rica study includes 616 children ages 6-14 years with ... effects of inhaled anti-inflammatory medications inchildrenwith mild to moderate asthma [26] Participating children had asthma defined by symptoms greater than times per week, use of an inhaled ... heterodimeric complex composed of TSLPR and IL7Ra chains [20] The TSLPR chain binds to TSLP at low affinity but its combination with the IL7Ra chain results in high-affinity binding and STAT5 activation...
... King J, Soldin SJ: IMMULITE 2000 age and sex-specific reference intervals for alpha fetoprotein, homocysteine, insulin, insulin-like growth factor-1, insulin-like growth factor binding protein-3, ... that, in critically ill childrenwith impaired glucose tolerance, b-cells can be dysfunctional, resulting in an inadequate compensatory increase in insulin release to the decreased insulin sensitivity ... seen in 33% of critically ill childrenwith meningococcal disease • Pathophysiologically, both a hyperinsulinemic and a hypoinsulinemic response play a role in the occurrence of hyperglycemia in...
... as part of the process of remodelling inasthma Other changes such as adventitial thickening [21] or increase in smooth muscle [22], which have not yet been quantified inchildrenwithasthma ... thickness in EB and BWT on HRCT inchildrenwith difficult asthma Also, no relationship was found between FEV1 (% predicted) and BWT on HRCT or RBM thickness in EB In keeping with our previous findings ... aims of the present study were therefore to investigate i) whether BWT, as shown on HRCT, can be used as a noninvasive indicator of RBM thickness in EB, in a group ofchildrenwith difficult asthma, ...
... multi-item index including subjective reporting of abdominal pain, general well-being, and diarrhea and physical findings, including linear growth and laboratory parameters (hematocrit, serum albumin, ... activity inchildrenwith mildly to moderately active, stable Crohn’s disease A dose of 1010 CFU twice a day resulted in intestinal colonization in all the patients, including those taking metronidazole ... baseline, mainly as a result of increased cellobiose absorption, reflecting increased intestinal paracellular permeability This parameter improved significantly on treatment with LGG, mainly...
... selecting a pain measurement tool in clinical settings 33 Assessment of other parameters inchildrenwith persisting pain 34 Overcoming the challenges of assessing persisting pain inchildren ... antidepressants of the class of serotonin and norepinephrine reuptake inhibitors for persisting neuropathic pain inchildren > 10 • Gabapentin for persisting neuropathic pain inchildren • Ketamine as ... clinical utility for children and adolescents with SCD in clinics, day hospitals and inpatient settings (51) 2.4Defining criteria and selecting a pain measurement tool in clinical settings In...
... of the EPA, the National Academy of Sciences Institute of Medicine issued a report on the role of indoor air quality in the growing asthma epidemic The report, “Clearing the Air: Asthma and Indoor ... increase in the number of students with asthma, but also an increase in the severity of the asthma Between 1980 and 1996, the prevalence ofasthma increased 45 percent among children ages 5-14 (Weiss, ... (see page 12) In spite of the common practice of maintaining zero-tolerance drug policies in schools, limiting student access to life-saving asthma medications is a dangerous decision In Houston...
... better with "depression" than the SF-36 domains assessing physical impairment In the subgroup of subjects defined as having an exacerbation ofasthma at the interview in 2002 (n = 143), the Page of ... of the questionnaires by calculating the extent of missing items within each HRQL instrument The analysis of measurement properties requiring a longitudinal assessment were beyond the scope of ... We identified a total of 615 individuals withasthmain the SAPALDIA cohort who participated in the second survey Out of 615 subjects, we included 258 individuals (42%) in the analyses, who had...
... organization of motor speech inchildrenwith mild forms of CP Conclusion Childrenwith mild spastic CP showed greater STIs in PS tasks, but not in MS tasks, than childrenwith TD These findings suggest ... period of a speech task was determined from the instance of peak closing velocity right before the initial opening of the lower lip to the instance when the lower lip was at the peak velocity of ... peak opening displacement, and peak opening velocity) obtained by dividing the standard deviation of kinematic data by the mean kinematic data Larger CV indicates higher variability of kinematic...
... active inflammation, including HMGB1 and pro-inflammatory cytokines, occurs inchildrenwith febrile seizures and pediatric epilepsy, we analyzed cytokine profiles in the serum of child patients with ... causative role of cytokines in epileptogenesis remains to be elucidated Cytokines may contribute initially to incite seizures in the developing brain after being induced by seizure or tissue injury, ... cytokine levels, including IL-1b, IL-8, IL-12p70, and macrophage inflammatory protein (MIP)1b, were significantly high in the epileptogenic cortex of intractable epilepsy children [17] In addition,...
... protein antibodies in some autistic children may be a mere association with the increased serum levels of neurokinin A in autism A more detailed understanding of the interactions between tachykinins ... correlations to eosinophil counts in both blood and sputum of asthmatic children during exacerbation [34] Thus, the reason behind the increase of serum neurokinin A levels in autistic children may ... first to investigate serum neurokinin A levels in autistic childrenIn a recent study some neuropeptides were investigated in autistic children It reported increased serum levels of neurotensin, while...
... Assistant Professor at the Institute of Genomic Medicine, UMDNJ-NJMS He has been involved in clinical studies of CGH, transcription profiling, and microRNA profiling in patients with various ... finding of impaired IL-6 production in ASD/SPAD children might be associated with development of SPAD in the ASD/SPAD children Decreased production of IL-10 may also indicate a possibility of ... its anti-inflammatory properties of TGF-ß [38] In addition, TGF-ß pathways closely interact with NOTCH and EGFR signaling pathways [31] Thus the findings from the transcription profiling of PB monocytes...