methods and approaches generally used for preclinical immunotoxicology assessment in rodents
Tài liệu Báo cáo Y học: Importance of the amino-acid composition of the shutter region of plasminogen activator inhibitor-1 for its transitions to latent and substrate forms pdf
... of the amino acids in positions 53 and 56 in a helix B, 186 in b strand 3A, and position 334 in b strand 5A (Fig 1; the numbering of amino acids in PAI-1 is according to the a1-antitrypsin template ... Lys335 in a1-antitrypsin, a1-antichymotrypsin, and antithrombin III resulted in an increased conformational stability and a decreased specific inhibitory activity [23,24] Lys335, localized in b strand ... strand 5A, points outward from the hydrophobic core and is conserved in 66% of serpins, the remaining serpins having Gln (10%), Ala (5%), and Arg (5%) in this position [3] In order to investigate...
- 10
- 431
- 0
Báo cáo khoa học: Subunit composition of the glycyl radical enzyme p-hydroxyphenylacetate decarboxylase doc
... were introduced into the existing clone of hpdB in pET11a The resulting plasmid contained the vector-derived RBS and 5¢-UTR in front of the hpdB gene but the clostridial RBS and 5¢-UTR in front ... hpdC gene was used to replace a StuI/BamHI fragment in pET-D3 Production of HpdB and HpdC in E coli The expression plasmids were used to transform several E coli host strains including DH5a [8] ... resulting proteins (MSQS to MASS in HpdB, MRKH to MGKH in HpdC and MSSQ to MASQ in HpdA) In contrast with the hpdC gene product, which was produced in a variety of host cells as a soluble protein,...
- 6
- 260
- 0
Báo cáo " Chemical composition of the leaf oil of Litsea glutinosa (Lour.) C. B. Rob. from Ha Tinh province " pptx
... new aporphine alkaloids, namely litseglutine A and B, along with two known aporphine alkaloids, boldine and laurolitsine [10] In the course of the systematic study of Litsea in Indochina, monoterpenes, ... cytotoxic activity against human Hela cell lines in vitro Chemical examination of the BuOH extract of the leaves and twigs of Litsea glutinosa collected from Xishuangbanna resulted in the isolation ... Tr n Huy Thái3 Khoa Sinh h c, Đ i h c Vinh, 182 Lê Du n, Vinh, Ngh An, Vi t Nam Khoa Hóa h c, Đ i h c Vinh, 182 Lê Du n, Vinh, Ngh An, Vi t Nam Vi n Sinh thái Tài nguyên Sinh v t, Vi n Khoa h...
- 4
- 411
- 2
Báo cáo khoa học: Suppression of nuclear factor-jB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles pot
... genes important for regulating in ammatory events in macrophages, including the expression of proinflammatory cytokines and chemokines [e.g tumour necrosis factor a (TNFa), interleukin (IL)-1b, IL-6, ... THP-1 macrophages were incubated with or without CRLPs containing n-6 PUFA (trilinolein) (0.29 lmol triacylglycerolÆmL)1) for or 24 h and NF-jB binding was measured using an ELISA based kit (TransAM) ... formation In summary, the studies examining NF-jB binding to DNA and expression of p65–NF-jB and pIjBa reported herein indicate that CRLPs inhibit NF-jB activation in THP-1 macrophages This conclusion...
- 14
- 328
- 0
Cancer of the Testis ppt
... cancers are staged within the SEER data using the categories in situ, localized, regional, distant, and unstaged Staging information on the cancer is also contained within the 10-digit Extent ... years Improvements in treatment, the most dramatic resulting from the introduction of cisplatincontaining combination chemotherapy in the 1970’s, have Tumor size National Cancer Institute 167 SEER ... on clinical, operative, and pathologic diagnoses of the cancer The EOD code encodes tumor size, extension of the tumor into surrounding tissues, and lymph node involvement We used EOD coding to...
- 6
- 236
- 0
báo cáo hóa học:" Research Article Global Estimates for Singular Integrals of the Composition of the Maximal Operator and the Green’s Operator" doc
... mathematics and physics In recent paper 10 , Ding and Liu investigated singular integrals for the composition of the homotopy operator T and the projection operator H and established some inequalities for ... studying deformations of elastic bodies, the related extrema for variational integrals, and certain geometric invariance Differential forms have become invaluable tools for many fields of sciences and ... Ms u and M# u are Ls -integrable 0-form s Differential forms, the Green’s operator, and maximal operators are widely used not only in analysis and partial differential equations, but also in physics;...
- 12
- 318
- 0
Báo cáo lâm nghiệp: "Chemical composition of the periderm in relation to in situ water absorption rates of oak, beech and spruce fine roots" doc
... below the rooting horizon Periods of low rainfall in summer irregularly lead to substantial water shortage in the sandy mineral soil and in the forest floor Gravimetric monitoring of soil water ... lignin contents in the periderm Scheffé’s test was also applied for comparing root diameter classes for their suberin and lignin contents in the periderm RESULTS 3.1 Root anatomy All oak, beech and ... absorption rates of terminal branch roots (diameter: 3–4 mm) of co-existing oak, beech and spruce trees measured in situ and relate them to the contents of suberin and lignin in the root periderm...
- 10
- 331
- 0
Báo cáo y học: " Mesothelioma of the testis and nephrotic syndrome: a case report" potx
... 150 mmHg and diastolic at 95 mmHg), and serum creatinine levels increased to 125 umol/l This was attributed to cisplatin renal toxicity, and then prednisolone decrease was continued In October ... hepatitis B and C viruses and against HIV, antinuclear antibodies and antineutrophil cytoplasmic antibodies were negative Serum levels of C3, C4 and CH50 were normal Oral prednisolone administration ... vaginalis testis (Figures and 2) Resection margins were invaded, thus a second surgical procedure was performed, with both a scrotectomy and an orchiectomy A staging work-up, with thoraco-abdominal...
- 4
- 295
- 0
Evaluation of the Characteristics of Microorganisms that Contribute to Denitrification in the Paddy Drainage Treatment Apparatus by Quinone Composition Measurement
... Akita-Komachi Rice, and the planting rate was 0.30 m (ridge pitch) and 0.15 m (planting pitch) The paddling and transplanting were conducted on June and June 8, and the inundation began on June in 2007 A ... analysis and does not require any biological and biochemical knowledge or skills Thus, the quinone profiling has high affinity with analysts Moreover, quinone composition used in quinone profiling ... contribution ratio for PC1 and PC2 was 62.3% Table shows the factor loading of PC1 and PC2 As for PC1, Q-8, Q-9, MK-9(H2) and MK-11(H2) indicated higher factor loading values Content of these quinones were...
- 7
- 570
- 0
Tài liệu Báo cáo Y học: CK2btes gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster potx
... phosphorylation by casein kinase in modulating Antennapedia activity in Drosophila Genes Dev 11, 1327–1340 Boldyreff, B & Issinger, O.-G (1997) A-Raf kinase is a new interacting partner of protein kinase CK2 ... Glover for providing us with the pEV55Dmß plasmid and the anti-DmCK2a antiserum, and to Dr H.D Hoyle for providing the testis vector We would like to thank Prof N.B Gusev for providing calmodulin and ... multiple substrates and a puzzling regulation FASEB J 9, 313–323 Pinna, L.A & Meggio, F (1997) Protein kinase CK2 (Ôcasein kinase-2Õ) and its implication in cell division and proliferation Prog...
- 10
- 464
- 0
Báo cáo khoa học: Protein transport in organelles: The composition, function and regulation of the Tic complex in chloroplast protein import pptx
... structure characteristic for CaM-binding domains, and contains at least one conserved potential CaM-binding motif [46] Additionally, the binding of CaM at the C-terminus and the binding of NADPH at the ... rate-limiting step for protein import in the mutant chloroplasts is not precursor unfolding [33,44] and could be interpreted as an indication for separate unfolding forces (and thus motor activities) in ... domains are degenerate 34-amino acid repeats forming anti-parallel a-helices known to be involved in an array of protein–protein interactions (generally with non-TPR proteins) [41] Both domains...
- 11
- 491
- 0
Báo cáo khoa học: Lysosomal localization of GLUT8 in the testis – the EXXXLL motif of GLUT8 is sufficient for its intracellular sorting via AP1- and AP2-mediated interaction docx
... bovine serum and 1% penicillin ⁄ streptomycin Transfection of fibroblasts with GLUT8 or GLUT8LL ⁄ AA plasmids was performed using Lipofectamine 2000 (Invitrogen) Adaptor protein and clathrin chain ... contains a transplantable internalization signal To determine the significance of the N-terminal dileucine signal in GLUT8 for its intracellular sorting, we constructed chimeric proteins comprising ... endosomal ⁄ lysosomal marker protein LAMP1, a finding that is in agreement with our in vitro binding data Targeting of GLUT8 in the absence of AP1 and AP2 In order to investigate the contribution of...
- 15
- 508
- 0
Comparison of composition (nutrients and other substances) of organically and conventionally produced foodstuffs: a systematic review of the available literature doc
... Glutathione, isoleucine, glycine, proline, glutamic acid, serine, threonine, alanine, cystine, methionine, leucine, tyrosine, phenylalanine, lysine, histidine, arginine, valine, aspartic acid ... baicalein, delfinidin 3-O-glucose, delfinidin 3O-rutinoside, cyanidin 3-O-glucose, cyanidin 3-Orutinoside, myricetin glucoside, myricetin rutinoside, myricetin malonylglucoside, aureusidin glucoside, ... glucosinolates, sulforaphane, indole glucosinolates, alphatic glucosinolates, glucoraphanin, glucoberin, progoitrin, sinigrin, gluconapin, 4-OHglucobrassicin, glucoerucin, glucobrassicin, 4-OCH3glucobrassicin,...
- 209
- 726
- 0
Báo cáo khoa học: Nuclear factor kappa B and tumor necrosis factor-alpha modulation of transcription of the mouse testis- and pre-implantation development-specific Rnf33⁄Trim60 gene pot
... embryo and in the testis, as reported in this work In the Rnf35 promoter, an Inr element, two binding sites for nuclear factor Y (NF-Y) and one binding site for the CCAAT-displacement protein (CDP) ... untranslated 5¢ exons and the acquired associated introns in activating expression of intronless protein-encoding genes, as for retrogenes [24–26] Interestingly, mutating both the Inr element and the aTATA ... PCR program was: pre-incubation at 50 °C for min; initial denaturation at 95 °C for min; and 45 cycles at 95 °C for 10 s, 63 °C for 15 s and 72 °C for 30 s The program was terminated by a final extension...
- 14
- 381
- 0
Báo cáo toán học: "Chemical composition and antibacterial activity of the essential oils from Launaea resedifolia L." docx
... used in folk medicine such as in bitter stomachic, skin diseases, and reported to have antitumor, insecticide, and cytotoxic activities The antimicrobial activities of coumarin constituents and ... are used in folk medicine in bitter stomachic, skin diseases, and reported to have antitumor, insecticide and cytotoxic activities [3] The antimicrobial activities of coumarin constituents [4] and ... kept at 4°C for h, and incubated at 37°C for 24 h The antibacterial activity was assessed by measuring the zone of growth inhibition surrounding the disks Each experiment was carried out in triplicate...
- 13
- 455
- 0
báo cáo hóa học:" Chemical composition and antibacterial activity of the essential oils from Launaea resedifolia L." potx
... used in folk medicine such as in bitter stomachic, skin diseases, and reported to have antitumor, insecticide, and cytotoxic activities The antimicrobial activities of coumarin constituents and ... are used in folk medicine in bitter stomachic, skin diseases, and reported to have antitumor, insecticide and cytotoxic activities [3] The antimicrobial activities of coumarin constituents [4] and ... kept at 4°C for h, and incubated at 37°C for 24 h The antibacterial activity was assessed by measuring the zone of growth inhibition surrounding the disks Each experiment was carried out in triplicate...
- 13
- 388
- 0
Báo cáo hóa học: " Chemical composition and antibacterial activity of the essential oils from Launaea resedifolia L" pdf
... at 37°C for 24 h The antibacterial activity was assessed by measuring the zone of growth inhibition surrounding the disks Each experiment was carried out in triplicate [16] The minimal inhibitory ... activities were observed against E coli and Pseudomonas aerugenosa with inhibition zones of 15 and 12 mm Against S intermedius, K pneumoniae, S pyogenes, P mirabilis, E coli and, P aerugenosa, the ... the diameter of the inhibition zone in millimeter Results obtained in the antibacterial study are shown in Table The results indicated that S aureus was the most sensitive strain to the oil of L...
- 4
- 478
- 0
Báo cáo hóa học: "NORM EQUIVALENCE AND COMPOSITION OPERATORS BETWEEN BLOCH/LIPSCHITZ SPACES OF THE BALL" potx
... S Stevi´ c In (1.4) and (1.6), Bn and Bn are interchangeable, since functions in ᏸ p (Bn ) extend continuously to Bn The supremum above is called the Lipschitz constant for f As in [8, page ... is standard and left to the reader Since functions in ᏸ p (Bn ) extend continuously to Bn , they are automatically in L1 (σ) [8, Remark, page 107] and since the quotients of these functions and ... (1.9) and we denote ∇U by ∇ when U is the typically ordered standard basis for Cn Let x and y be two positive variable quantities We write x y (and say that x and y are comparable) if and only...
- 11
- 300
- 0
THE COMPOSITION OF DRY-FARM CROPS ppsx
... students For instance, Mayer, working in Holland, found that, in a soil containing throughout the season 10 per cent of water, oats was produced containing 10.6 per cent of protein; in soil containing ... striking and convincing The original seed grown in Kansas in 1905 contained 16.22 per cent of protein The 1906 crop grown from this seed in Kansas contained 19.13 per cent protein; in California, ... grown in Maine and in the Middle West 11.69 and 11.51 per cent of protein respectively The moist and dry gluten, the gliadin and the glutenin, all of which make possible the best and most nourishing...
- 14
- 303
- 0
Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008