... Chen B, et al Ex vivo expansion and in vivo infusion of bone marrow-derived Flk-1+CD31-CD34- mesenchymalstem cells: feasibility and safety from monkey to human StemCells Dev,2006,15(3):349-357 ... rhesus mesenchymalstemcells infusion and detection of chimerism J Sec Milit Med Univ 2005,26(3):263-266 Chamberlain G, Fox J, Ashton B, Middleton J Concise review: mesenchymalstem cells: their ... immunological features, and potential for homing StemCells 2007 Nov;25(11):2739-49 Yagi H, Soto-Gutierrez A, Parekkadan B, et al Mesenchymalstem cells: mechanisms of immunomodulation and homing Cell...
... engineering and regeneration [134] Mesenchymalstemcells versus embryonic stemcells Embryonic stem (ES) cells are derived from the inner cell mass of the embryonic blastocyst These cells can ... ‘bone marrow stem cell’, which is often used for either hematopoietic or mesenchymalstem cells, the central nervous system stem cell, the hepatic stem cell, etc.? If many stemcells are found ... supports the survival and differentiation of stemcells These complementary approaches have been used to compare different groups of stemcells in order to identify core stem genes and to examine...
... capacity of human bone marrow mesenchymalstem cells: comparison of chemokine and growth factor chemotactic activities StemCells 2007, 25:1737-1745 24 Segers VF, Van RI, Andries LJ, Lemmens K, Demolder ... transmigration and invasion of mesenchymalstemcells J Mol Cell Cardiol 2008, 44:1072-1084 30 Estrada R, Li N, Sarojini H, An J, Lee MJ, Wang E: Secretome from mesenchymalstemcells induces ... marrow stromal cellsStemCells 2001, 19:219-25 10 Burt RK, Loh Y, Pearce W, Beohar N, Barr WG, Craig R, et al.: Clinical applications of blood-derived and marrow-derived stemcells for nonmalignant...
... ESCs StemCells 25, 425–436 Liu, C.H., Hwang, S.M., 2005 Cytokine interactions in mesenchymalstemcells from cord blood Cytokine 32, 270–279 Minguell, J.J., Erices, A., 2006 Mesenchymalstemcells ... 2004 Mesenchymalstemcellsand their potential as cardiac therapeutics Circ Res 95, 9–20 Quesenberry, P.J., Aliotta, J.M., 2008 The paradoxical dynamism of marrow stem cells: considerations of stem ... Carcinoma 40 Nephrology Renal and Urological Disease Renal and Urological System Development and Function Hair and Skin Development and Function Dermatological Diseases and Conditions Cardiovascular...
... marrowderived mesenchymalstemcellsand mononuclear cellsStemCells 25, 1166–1177 Li L, Zhang S, Zhang Y, Yu B, Xu Y & Guan Z (2009) Paracrine action mediates the antifibrotic effect of transplanted mesenchymal ... human mesenchymalstemcells Science 284, 143–147 Porada CD, Zanjani ED & Almeida-Porad G (2006) Adult mesenchymalstem cells: a pluripotent population with multiple applications Curr Stem Cell ... X, Hu S & Chen X (2008) Lysophosphatidic acid protects mesenchymalstemcells against hypoxia and serum deprivation-induced apoptosis StemCells 26, 135–145 21 Li Z, Wei H, Liu X, Hu S, Cong X...
... Epithelial mesenchymal transitions: twist in development and metastasis Cell 118, 277–279 31 Zipori D (2004) Mesenchymalstem cells: harnessing cell plasticity to tissue and organ repair Blood Cells ... Huang CT, Tsai CC, Shen EY & Chiu WT (2005) Isolation and characterization of neurogenic mesenchymalstemcells in human scalp tissue StemCells 23, 1012–1020 In’t Anker PS, Scherjon SA, Kleijburg-van ... of mesenchymalstemcells of fetal or maternal origin from human placenta StemCells 22, 1338–1345 Bieback K, Kern S, Kluter H & Eichler H (2004) Critical parameters for the isolation of mesenchymal...
... Currently, several candidates of stem cells, including embryonic stem cell, neuron stem cells, bone marrow-derived mesenchymalstem cell, and peripheral blood-derived stemcells have been frequently ... adipose-derived mesenchymalstemcells (ADMSCs) for the treatment of stroke has seldom been discussed [19] Compared with embryonic stems cellsand bone marrow-derived mesenchymalstem cells, ADMSCs ... marrow-derived mesenchymalstemcells [15-17], embryonic stemcells [14] and endothelial progenitor cells [18], have been extensively investigated in the treatment of stroke in experimental studies and, ...
... cellsand the host tissue As compared with embryonic stems cellsand bone marrow-derived mesenchymalstem cells, adiposederived mesenchymalstemcells (ADMSCs) have the distinct advantages of being ... J, Ratajczak MZ: Trafficking of normal stemcellsand metastasis of cancer stemcells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis StemCells 2005, 23:879-894 Kee HJ, Sohn IS, ... Page of 16 andand between groups and (Figure 4A) However, this protein expression was substantially lower in group than in other groups and notably lower in groups and than in groups and (Figure...
... regulatory properties [1,8] Adult stemcells are known to have a limited differentiation potential while embryonic stemcells are totipotent Multipotent stemcells were first isolated from adult ... bottom of the tube (Fig 3D), and positive to toluidine blue staining (Figs 4E and F) Discussion Isolation and characterization of stemcells derived from various tissues and sources have been one ... increasing the passage number of adult stemcells often leads to a decline in the multipotent abilities [36] Human mesenchymalstemcells could be proliferated and have differentiation abilities...
... phenotype and direct the cells to form a new and appropriate matrix Materials and methods Mesenchymalstem cell source and extraction Bone marrow samples were received from two patients (aged 66 and ... Hoyland JA: Intervertebral disc cell-mediated mesenchymalstem cell differentiation StemCells 2006, 24:707-716 27 Richardson SM, Hughes N, Hunt JA, Freemont AJ, Hoyland JA: Human mesenchymalstem ... disc-like cells from adult mesenchymalstemcellsStemCells 2005, 23:403-411 44 Risbud MV, Albert TJ, Guttapalli A, Vresilovic EJ, Hillibrand AS, Vaccaro AR, Shapiro IM: Differentiation of mesenchymal...
... I and class II expression by IFN in adherent cells (a) One example of basal and IFN-γ-induced expression of HLA-A, HLA-B, cells HLA-C (left) and HLA-DR (right) molecules on mesenchymalstemcells ... standard error of the mean One representative experiment out of six different samples of bone marrow mesenchymalstemcells (three normal, two osteoarthritis and one rheumatoid arthritis) and ... embryonic stemcells [40] The maintenance of pluripotency of embryonic stemcells could involve Wnt signaling and could occur through a crosstalk between the transforming growth factor beta/activin and...
... mesenchymalstem cells: characterization, differentiation, and application in cell and gene therapy J Cell Mol Med 2004, 8:301-316 31 Tuan RS, Boland G, Tuli R: Adult mesenchymalstemcellsand ... marrow and cord blood mesenchymalstemcells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases StemCells 2006, ... markers and pulse–chase techniques can be used to label stemcells [79] In other systems, asymmetric division has been shown to be integral to stem cell self-renewal This unique property of stem cells...
... concentration and annulus cells adiposederived mesenchymalstem of AD-MSCfor 3D co cultured alone Increase in separate culture cells (AD-MSC) and annulus cells comderived mesenchymalstemcells (AD-MSC) and ... interactions of adult mesenchymalstemcellsand disc cells by Le Visage et al [20] showed that annulus, but not nucleus, cells co-cultured in chondrogenic pellets with mesenchymalstemcells had approximately ... formed by sand rat adipose-derived mesenchymal extracellular 3D factor in the Immunohistochemical documentation ofstem cellsgrowthculture beta sand rat adipose-derived mesenchymalstemcells in...
... and AR50249 from to National Institute of Arthritis and Musculoskeletal and Skin Diseases to SCG and CHE, by grant STE 1051/2-1 from the Deutsche Forschungsgemeinschaft (DFG) to AFS and UN, and ... D-23 to AFS and AR from the Interdisciplinary Center for Clinical Research (IZKF) Würzburg References Kolf CM, Cho E, Tuan RS: Mesenchymal stromal cells Biology of adult mesenchymalstem cells: regulation ... cultured human mesenchymalstemcells from marrow Tissue Eng 1998, 4:415-428 35 Mueller MB, Tuan RS: Functional characterization of hypertrophy in chondrogenesis of human mesenchymalstemcells Arthritis...
... Akt and ERK for stage III cells There was a baseline of Akt and ERK phosphorylation without adding ECM FN and LAM increased phosphorylation of Akt and ERK, and LAM had greater effects on Akt and ... size-sieved stemcells into electrically active neural cellsStemCells 2002, 20(6):522-529 Tzeng SF, Tsai MJ, Hung SC, Cheng H: Neuronal morphological change of size-sieved stemcells induced ... human mesenchymalstemcells into insulin producing cells J Biomed Mater Res A 2008, 86(4):1097-1105 Chao KC, Chao KF, Fu YS, Liu SH: Islet-like clusters derived from mesenchymalstemcells in...
... 20:94-101 Chen L, Tredget EE, Wu PY, Wu Y: Paracrine factors of mesenchymalstemcells recruit macrophages and endothelial lineage cellsand enhance wound healing PLoS One 2008, 3:e1886 Gnecchi M, ... the enhanced stemcells survival and greater differentiation rate of MSCs into vascular cells when administrated with simvastatin simultaneously In vitro, a higher cell proliferation and decreased ... expression and enchance cells survival Kortesidis and colleagues also demonstrated[31] that bone marrow derived-MSCs express factors that support cell survival and avoid apoptosis thereby preserving cells...
... inhibited apoptosis and improved heart function StemCells 2007, 25:2118-2127 Wang D, Shen W, Zhang F, Chen M, Chen H, Cao k: Connexin43 promotes survival of mesenchymalstemcells in ischaemic ... homologous recombination and propagated in 293 cells At stipulated time, the supernatant from 293 cells was collected and purified on cesium chloride (CsCl) gradient centrifugation and stored in 10 mmol/L ... mononuclear andmesenchymal bone marrow cells in acute and chronic rat myocardial infarction J Mol Cell Cardiol 2006, 41:876-884 Tang YL, Tang Y, Zhang YC, Qian K, Shen L, Phillips MI: Improved graft mesenchymal...
... potential of adult human mesenchymalstemcells Science 1999, 284:143-147 Pittenger MF, Mosca JD, McIntosh KR: Human mesenchymalstem cells: progenitor cells for cartilage, bone, fat and stroma Curr Top ... engineering by providing abundant seeding cells with high quality List of abbreviations ADSCs: adipose-derived mesenchymalstem cells; MSCs: mesenchymalstem cells; ALP: alkaline phosphatase; DT: ... by lipolytic hormones and insulin J Biol Chem 1966, 241:3909-3917 Lange C, Schroeder J, Stute N, Lioznov MV, Zander AR: High-potential human mesenchymalstemcellsStemCells Dev 2005, 14:70-80...
... Figure Mesenchymalstemcells (MSCs) inhibit the proliferation of CD4 + T cells in vitro by induction of nitric oxide and prostaglandin E2 (PGE2) (a) CD4+ T cells, in the presence of accessory cells, ... mesenchymalstemcells Blood 2007, 109:228-234 11 English K, Barry FP, Field-Corbett CP, Mahon BP: IFN-gamma and TNFalpha differentially regulate immunomodulation by murine mesenchymalstemcells ... regulatory T cells inhibit osteoclastogenesis and collagen-induced arthritis Ann Rheum Dis 2009, 68:744-750 Kolf CM, Cho E, Tuan RS: Mesenchymal stromal cells Biology of adult mesenchymalstem cells: ...