... Hematopoietic growthfactors Therapeutic use Hematopoietic growthfactors Mechanism of action Cancer-Chemotherapy [DNLM: Hematopoietic Cell GrowthFactors therapeutic use Hematopoietic Cell GrowthFactors ... on growthfactors In cultures, these growthfactors were provided by serum, conditioned medium, or cell underlayers The growthfactors present in these sources were called colony-stimulating factors ... Hematopoietic GrowthFactors 375 Roy E Smith and Barbara C Good 20 Long-Term Safety of Filgrastim in Chronic Neutropenias 395 Karl Welte 21 Economics of Hematopoietic GrowthFactors ...
... function L J Reigstad et al endothelial growthfactors (VEGF) and the family is therefore often referred to as the PDGF ⁄ VEGF family The PDGF family of growthfactors The PDGF family consists of ... Mapstone T, McMichael M & Goldthwait D (1991) Expression of platelet-derived growth factors, transforming growth factors, and the ros gene in a variety PDGF-C and -D, structure and function 105 ... underlying mechanisms are still to be understood In the aortic ring outgrowth assay, PDGFC mediated significant increased outgrowth of fibroblasts and smooth muscle cells, to a degree comparable...
... homodimer growth factor remain associated after proteolytic cleavage [2–4] The prodomain ⁄ growth factor complexes confer latency on the growthfactors and the active homodimeric growthfactors ... physiological relevance Growth factor binding proteins may control the action of growthfactors not only by inhibiting their action, but also, by serving as a reservoir for growth factors, may localize ... of the binding of these growthfactors to their cognate receptors To answer these questions, we studied the ability of WFIKKN proteins to block the binding of growthfactors to their receptors...
... Candidate Growth Factor Peptide Ligand Signals 792 Examples of Peptide Growth Factor Signaling Pathways 792 GrowthFactors and Lung Development 792 Candidate GrowthFactors in Lung Development 792 Growth ... Transforming Growth Factors- a, Neuregulins and Epidermal GrowthFactors 246 Ligands, Receptors and Expression during Neurogenesis 247 Function during Neurogenesis 247 Transforming Growth Factors- b ... Development 722 Fibroblast GrowthFactors 722 TGFb Family 725 Sonic Hedgehog 729 Wnt Family 730 Tumor Necrosis Factors 732 Other GrowthFactors 733 Integrations between Growth Factor Signal Pathways...
... bone matrix apposition in vitro by local growth factors: a comparison between Insulin-like growth factor I, platelet-derived growth factor and transforming growth factor beta Endocrinology 1990, ... cultured for three days The test were conducted in triplicate and repeated two times Growthfactors The growthfactors were applied to the cell culture from a local drug delivery system The drug ... collagen-1 and osteocalcin synthesis was observed after treatment with growthfactors (data not shown) C2C12 cell line All three growth factors, PDGFbb, IGF-I and BMP-2, stimulated significantly the...
... anticatabolic [13] actions of TGF-β, any maneuver that modifies responses to TGF-β and other anabolic growthfactors could have critical consequences for maintenance and repair of cartilage These studies ... was added Proteoglycan synthesis or proliferation was determined 24 hours after addition of growthfactors Phosphorylated p38 MAPK was determined as an index of activation using a commercially ... p38 mitogen-activated protein kinase inhibition blunts transforming growth factor beta (TGF-β)-stimulated, but not insulin-like growth factor (IGF-1)-stimulated, proteoglycan synthesis Rabbit chondrocytes...
... Respiratory Research Vol No Allen and Spiteri Growth factors: multiple profibrogenic functions Individual growthfactors involved in the development of pulmonary fibrosis invariably ... of growthfactors with these epithelial and fibroblast cell types that are most critical in determining whether the ultimate outcome of wound-healing responses to lung injury is IPF Growthfactors ... angiogenesis Much less is known about how growthfactors regulate AEC function to modulate fibrogenesis but, in AECs obtained from IPF patients, growthfactors are potentially responsible for secretion...
... vascular endothelial growth factor architecture of the airspaces (see Fig 1) An analysis of their role in development and disease follows Growthfactors in development Growthfactors are involved ... EGF, epidermal growth factor; FGF, fibroblast growth factor; GM-CSF, granulocyte macrophage-colony stimulating factor; PDGF, platelet-derived growth factor; TGF, transforming growth factor; VEGF, ... Respiratory Research Vol No Desai and Cardoso Figure Growthfactors in development and disease Major roles of selected growthfactors in embryonic and postnatal lung development (left)...
... factors that could influence secondary metabolite in plant cell cultures have been found [2,7] Optimization of the hormone concentration and combination are often effective For ginseng cell growth, ... suspended cells of ginseng in shake flask, the effect of plant growth regulators (2,4-D or IBA or NAA combination with BA or kinetin) on cell growth, ginsenoside production by cultured cells were focused ... optimal for the cell growth (10.1 g/L DW) and ginsenoside (7.29 mg/g DW total ginsenoside) of ginseng suspension culture Addition of cytokinins (BA and kinetin) did not affect cell growth but ginsenoside...
... Economic growth -> expressed on a per capita basis -> growth rate of GDP per capita -> output per person • GDP per capita = GDP / Population • Growth Rate of GDP per capita = Growth Rate of GDP – Growth ... (Vietnam Government Web Portal News) Two main factors Contribution of Capital stock, Labor and TFP to the GDP Growth (%) (calculated from data in GSO) Two main factors Vietnam’s economy † development ... Table of contents Background information Two main factors 2.1 Capital stock 2.2 Labor force Background information • Economic growth • increase in the amount of the goods and services...
... the transcription of a number of target genes S6K Growth control by FOXO factors elF4E rpS6 Cell growth and division Figure The dFOXO protein mediates a transcriptional response to insulin signaling ... multiple layers of insulin-mediated growth regulation Control of gene expression by FOXO factors in response to insulin allows integration of transcriptional activities with other growthrelated processes ... http://jbiol.com/content/2/3/18 (a) Cell growth Cell division (b) Cell growth Cell division (c) dFOXO overexpression Cell growth Cell division (d) Wild-type chico−/− Cell growth Cell division dS6K−/− Figure...
... increment is directly predicted by species specific functions of site factors, tree size factors and distance independent competition factors ing in large trees never dying Therefore the results of ... potential for ingrowth as well as (ii) the number of ingrowth trees for a 5-year period on the certain plot and (iii) the species, (iv) the dbh and (v) the height of every ingrowth tree The coefficients ... expected U-shaped mortality rate over dbh Mortality model Ingrowth in terms of ANFI means that trees exceed the cm dbh threshold The ingrowth model according to Ledermann (2002) consists of species...
... Thus the vegetation structure, composition and rate of growth were a function of the site conditions (as determined by climatic, physiographic and site management factors) To eliminate competition, ... occurred between the growth of trees in the weedy and weedfree treatment was determined by plotting tree growth curves for height, crown or groundline diameter Divergence of the growth curves was ... variables across sites, in conjunction with site management factors (such as burning) had an influence on the time taken for competitioninduced tree growth suppression to occur MATERIALS AND METHODS 2.1...
... relationships between streamwater chemistry and some complex environmental factors, such as altitude Factors determining the streamwater composition in the Vosges Mountains and relief [24, 32], catchment ... colluvial deposits originating from intermediate sandstone occur [7] Soils developed from conglomerate are especially shallow and rich in boulders On Intermediate and Senones sandstones, clay release ... –0.47 0.20 –0.26 –0.06 –0.48 0.09 –0.44 0.10 –0.10 IS 372 T Nedeltcheva et al Factors determining the streamwater composition in the Vosges Mountains 373 Table IV Catchments characteristics and...
... and Gelrite® (Kelco) on the growth of in vitro walnut explants, their mineral content and the typical naphthoquinone content associated with the abovementioned factors al, 1989) As result of ... capillaries of the gels (Debergh, 1983), it is expected that the gelling agents alter the composition of the media in proportion to the quantities (0.6% agar and 0.2% Gelrite, w:v) required for medium ... significant accumulation of these elements does not occur before growth inhibition takes place cause It has been shown that reduced growth is accompanied by decreasing amounts of the hydrojuglone...
... the root becomes dormant (Wilcox, 1954; John- growth son-Flanagan and Owens, 1985), yet the growth can remain unaltered over repeated cycles of growth and dor- direction of mancy Furthermore, ... tip and blocking its growth by coating it with plaster, showed that the progressive development of a rather stable plagiotropism by the lateral roots was related to the growth rate of the taproot, ... redistribution of growth regulators, including indole-3-acetic acid and abscisic acid (ABA), which become unevenly distributed in the upper and lower parts of the root Unequal growth rates then...
... effects of both climatic and nonclimatic factors on the radial growth of trees It is possible to evaluate the effects of nonclimatic factors on the radial growth of trees in the past by comparing ... might reduce the radial growth of Yezo spruce trees in the 1970s are not shown in the climatic data These results indicate that nonclimatic stress factors reduced the radial growth of Yezo spruce ... the radial growth by applying the statistical techniques that are used in dendrochronology This method might be useful to assess the effects of nonclimatic stress factors on tree growth in the...
... arthritis, angiogenic growthfactors are induced and outweigh the inhibitors, resulting in the initiation of angiogenesis [4] Among the angiogenesis inducers, vascular endothelial growth factor (VEGF) ... inappropriate synthesis of angiogenic factors or an inhibition by angiostatic factors The aim of the present study was to analyze whether a decrease of the angiogenic factors VEGF and bFGF and an increase ... human VEGF165 with crossreactivity to VEGF121, but not to factors related to VEGF such as human placental growth factor and plateletderived growth factor Interassay and intra-assay variances were...
... litter weight at weaning with IVGP were significant DISCUSSION 4.1 Growth and carcass composition traits For most growth and carcass composition traits, the heritability values found here are in agreement ... sélection de la carcasse / caractères de reproduction / composition INTRODUCTION In past French pig breeding programmes, selection for higher growth rate, better feed efficiency and lower backfat ... Hal&dquo; and RN- alleles In both selected and control lines of this experiment, a number of growth, carcass composition and reproductive traits was measured over the six generations of selection in...
... gene / RN gene / meat quality / carcass composition R´sum´ – Comparaison des trois g´notypes RN chez le porc pour les caract`res e e e e de croissance, de composition de la carcasse et de qualit´ ... condition (RTN, GP and ultimate pH), as well as on growth performance and carcass quality Results concerning the effects of the three RN genotypes on chemical composition, enzyme activities and myofiber ... genotype RN− /RN− RN− /rn+ rn+ /rn+ Postweaning growth performance (1) 103 (11) 92 (11) 69 (9) In vivo muscle glycolytic potential 98 88 66 Carcass composition, Napole yield and physico-chemical...