... matching of protein spots first to reference gels ofthe same condition and thereafter to reference gels common to both conditions The stepwise annotation of protein spots to two independent levels of ... (Fig 1) The four level match-sets are the reference gels ofthe respective quadrants from the 2D gel sections of each condition and the four higher-level match-sets are the reference gels ofthe ... the major role ofthe MMP family is the control of cellular responses critical to homeostatic regulation ofthe extracellular environment and the immune response [19,20] We decided to apply protease...
... R5 to 2.5 V on the input ofthe ADC (the maximum input voltage of ADC4 ofthe MSP430) 5.2 Environment Emulator: Software We already know that the capacitance (stated in terms ofthe amount of ... emulator We measure the current consumed by the DUT, and we set the output voltage The characteristics ofthe energy harvester and the storage element are implemented in software Figure is the ... part ofthe EE On the EE we connected VDD (voltage drain drain) tothe USB power ofthe board The ADC (analog -to- digital converter) and DAC (digital -to- analog converter) lines are connected to...
... sensitivity to Ca2+ [29, 30] The initial release occurs in the vicinity ofthe plasma membrane It spreads into the cell through the regenerative release of Ca2+ by the RyR and /or the IP3R in the form of ... RyR to produce sparks, but provides the necessary amount of Ca2+ to charge up the ER and sensitize the RyR [52] Another way of internal store reloading is achieved by the various isoforms ofthe ... representing the position ofthe particle, were also taken to represent the position ofthe myosin head The position ofthe myosin head, determined by the above method, was compared between the two...
... further evidence ofthe potential beneficial effects of these type of compounds in the treatment of inflammatory diseases ofthe airways Anticholinergics In two poster presentations Dr A Anzueto ... extracellular proteolysis These effects also support the use ofthe compound in the treatment of COPD Kinase inhibitors A new addition tothe PDE4 inhibitor field is Roflumilast, a potent and ... characterisation of a model of elastase-induced emphysema in the mouse This model may be of great use tothe many groups now seeking to study and develop drugs for the treatment of COPD Dr DC Underwood...
... Section 2.2.2 NATIONAL UNIVERSITY OF SINGAPORE SINGAPORE 1.5 Organization ofthe Thesis 24 1.5 Organization ofthe Thesis The following highlights the contents of each ofthe remaining chapters Chapter ... by (1.6) has to be reformulated to take into account: (i) the effect of w(t) and (ii) the interpretations of constraints (1.6d) and (1.6e) in the presence of w(t) For the control of system (1.10), ... priori in the parametrization, one method of designing this feedback gain is introduced to control the asymptotic behavior ofthe closed-loop system The underlying idea ofthe method is that the support...
... and the condition ofthe accuracy ofthe approximation is given 1.3 Objectives and Scope ofthe Thesis This thesis attempts to improve and characterize several issues of MPC control law: the ... chosen to provide a large XN via the use of a short N The size of X f depends on the choice of K Similarly, K affects the size of F∞ from (2.32) for a fixed W Hence, the choice of K is a trade-off ... be computed off-line, the on-line work at time t is simplified tothe identification ofthe polytope CR j which x(t) belongs to and then the computation of c∗ (t) from (3.21) Note that the on-line...
... mechanism may exist to facilitate the viral replication These findings would stimulate further investigation to unveil the regulatory mechanisms that honey bees use to control the pattern of replication ... to RT-PCR to assess the sensitivity ofthe assay A) Amplification plots were generated by using seven serial dilutions ofthe RNA, ranging from 103 pg to fg per reaction as the template for the ... transmission of DWV and suggested that the lining ofthe digestive tract was likely the primary site ofthe DWV infection via food-borne transmission, with the virus spreading to secondary sites from the...
... provider’s topology from the customer’s perspective The customer is aware ofthe core due tothe information he received regarding the VCs, but has no other knowledge The same ideals apply to customer ... with the CE routers there are mechanisms in place to limit the impact of DoS attacks tothe VPN where they originated Which equates tothe way these attacks are handled in Frame-Relay and ATM based ... able to handle this by some ofthe methods already addressed in previous sections As the provider only tells the customer about VCs there is a lack of places to attack Also due tothe fact they...
... with the nt sequence ofthe open reading frame (ORF) of their cDNAs and the corresponding aa sequences, in Table Summary ofthe purification of DNases I from the pancreases of three species of snake ... corresponding tothe nt sequences ofthe cDNA from positions 28–48 and 867–885, respectively The amplified fragment was ligated into the pcDNA3.1 (+) vector (Invitrogen) to construct the expression vector ... cloned the cDNA of each A single amino acid (aa) substitution was confirmed to affect the thermal stabilities of vertebrate DNases I and, furthermore, one ofthe postulated mechanisms whereby thermal...
... In the absence of a clinical evaluation, a simulator was developed to simulate 70 days of data and test the ability ofthe system to store large amounts of data and to manipulate these data to ... including the requirement to identify the monitored subject from others in the home (Biometrics signature), IR conflicts and the inability to monitor the subject outside ofthe home environment Monitoring ... have the ability to identify the monitored subject, and distinguish between their location and the location of others if the monitored person is living with others or regularly receives visitors...
... various steps in the cytotoxic activity ofthe drug, from a decrease ofdrug accumulation in the cell to abrogation of apoptosis induced by the chemical substance Often several different mechanisms ... release of these drugs (ADR and VCR) [5] PrPC-mediated multidrug resistance (MDR) was thought to be related to upregulation of P-glycoprotein (P-gp) [6] and inhibition of apoptosis [6–9]; these ... 25% ofthe tumor cells exhibiting IR; 2, 25–50% ofthe tumor cells exhibiting IR; 3, 50–75% ofthe tumor cells exhibiting IR; 4, > 75% ofthe tumor cells exhibiting IR The overall score was the...
... boundaries, off tothe syntactic parser The f'n'st task is to find the prosodic constituents, i.e to find where the syllables are, where the feet ~ are, and where the prosodic words are The particular ... number of clitics which are suffixes as far as the phonology is concerned (i.e., they undergo Vowel Harmony with the word to which they attach) are separate words from the point of view ofthe syntax ... suffixation of an affix to a prescribed prosodic subconstitucnt of a word rather than tothe whole word 2.2 The Non.Isomorphism of Morphophonology and Morphosyntax Another fundamental property of morphology...
... 3, cf Luhn (1958)) Then, the weight of each cluster is calculated by dividing the square ofthe number of significant words in the cluster by the total number of words in the cluster Sentences ... a Satellite (Marcu (2000)) The Nucleus is the equivalent ofthe arc destination, and the Satellite is the equivalent ofthe arc origin in the non-treebased approach The symmetrical or undirected ... other sentences relate to them (Sparck-Jones (1993)) The first method consists of simply determining the in-degree of each node in the graph A node represents a sentence, and the in-degree of...
... as DFMO retards the growth ofthe pancreas [101], but does not inhibit the secretory function ofthe exocrine part ofthe organ [102] The cellular functions ofthe polyamines in the pancreas were ... protocol A plausible explanation for the failure to inhibit tumorigenesis is the competition ofthe mutant ODC for the binding ofthe antizyme and releasing the wild-type enzyme [52] The mechanisms ... SSAT The apparent synergism between the polymorphism ofthe ODC gene and the use of aspirin was proposed to be a combined result of an inhibition of polyamine biosynthesis and an activation of their...
... whereas in the sentence “They arrived tothe town” the preposition to is a confusion error (cf arrived in the town) Most work on automated correction of preposition errors, with the exception of Gamon ... sentences and removed them 510 N Mw = i N FPw = i In the above equations, N is the total number of instances, ci is the class (1 or 0) , and pi sys crowd indicates the proportion ofthe crowd that classified ... English speakers They were asked to annotate the preposition usage instance as one ofthe following: extraneous (Error), not extraneous (OK) or too hard to decide (Unknown); the last category...
... not easy to conceive of Ireland, Denmark, and Russia without potatoes However, both tomatoes and potatoes are of New World origin (figure 1.1) At the time of their introduction into the Old World, ... lineages to be placed sister tothe wild progenitor populations Evolutionary History ofthe Domesticated Sunflower 37 from which they were derived, and this is not the case On the other hand, given the ... accept these crops because they were similar to local poisonous plants (deadly nightshades), they were thought to cause disease (under the Doctrine of Signatures the swollen tubers of potato were...
... shown to be the reason for up to 75% ofdrug switches for toxicity within the first three years of first-line HAART [21] In South Africa, there is an ongoing debate about whether or not the side-effect ... shown to impact negatively on both physical and mental HRQoL [10,31] However, the nature ofthe symptoms and whether they were attributed tothe disease process or to HAART was not clear In the ... Limitations tothe study included possible selection bias and information bias related tothe use ofthe MOS-SF36 instrument The loss of up to 50% of patients, who had incomplete HRQoL data, from the...
... and the warm familiarity of history -of the Jazz Age, ofthe Great Depression, of Reaganomics, and so on Third, I would like to extend the good luck of past generations to those ofthe present The ... nobles, and tithes, a strict tenth ofthe gross produce ofthe peasants down tothe potherbs in their gardens and two shillings in the pound from the personal earnings ofthe expanding class of shopkeepers ... unable to know the place of economics within the broader community of INTRODUCTION ideas, much less be able to explain it tothe uninitiated We will be unable to engage in the rhetoric ofthe intellect...