mechanical alloying and mechanochemical activation
Báo cáo y học: "Mechanical complications and reconstruction strategies at the site of hip spacer implantation"
... techniques for management of extensive loss of femoral and/ or acetabular bone Mechanical complications and reconstruction strategies The exact rate of mechanical complications following hip spacer implantation ... lavage and debridement However, in some cases with a combined muscular insufficiency and large acetabular defects a spacer dislocation might still occur These cases should be also considered as candidates ... neck fracture and frequently associated with a subsequent spacer head dislocation In these cases treatment should consist of revision surgery and spacer exchange On the other hand, asymptomatic...
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Báo cáo khoa học: Modulation of glucocorticoid receptor-interacting protein 1 (GRIP1) transactivation and co-activation activities through its C-terminal repression and self-association domains pptx
... modulation of self-transactivation (AD1 and AD2) and co-activator (AR, ER and TR) functions in HeLa cells The outcome of the relationship between GRIP1 transactivation and co-activator functions ... might have resulted from inter- and intramolecular interactions within its C-terminal and other regions Hence, the modulation of GRIP1 transactivation and co -activation activities through its ... proteins, CoCoA and GAC63 [29,30] In this study, we investigated the regulation of GRIP1 transactivation and co -activation activities by its own C terminus through the repression and selfassociation...
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Báo cáo khoa học: "Mechanical Translation and Computational Linguistics" pptx
... allow our rough -and- ready everyday understanding of the term "stimulation" to carry us along as we discover the manner in which Quine understands the relation of prompting If, as I stand beside a ... letters and arrows each time they undertake to obey a command In another (game 38), after being trained to follow a written order, the inhabitants are shown the table of letters and arrows once and ... the very reaction described in 37) and 38), and in fact our usual reaction when for instance we hear and obey an order? For, the fact that the training in 38) and 39) preceded the carrying out...
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Báo cáo Y học: Identification of residues in the PXR ligand binding domain critical for species specific and constitutive activation docx
... drug-induced hepatomegaly and decreased bile acid excretion [16] The aim of this study was to explore the molecular mechanism of ligand binding and activation of PXR by modeling and site-directed mutation ... Pregnenolone-16a-carbonitrile (PCN) and SR12813 (Fig 2) All compounds are well characterized ligands for human and mouse PXR, where rifampicin and SR12813 are potent activators of the human receptor and PCN primarily ... omega-loop and beta-sheet of the protein and contained the following residues: 175–236, 302 and 308–320 Two short additional loop regions were poorly modeled: residues 385–387 between helices and 10 and...
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Báo cáo khoa học: cAMP inhibits CSF-1-stimulated tyrosine phosphorylation but augments CSF-1R-mediated macrophage differentiation and ERK activation potx
... HRPconjugated rabbit anti-goat and swine anti-rabbit IgGs (DAKO, Glostrup, Denmark); PD98059 (New England Biolabs, Inc., Ipswich, MA, USA); PGE1 and PGE2 (ICN); and the sodium salt of 8BrcAMP ... (2002) Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 ... kinase activity and the kinase insert region in ligand-induced internalization and degradation of the c-fms protein Embo J 10, 877–883 27 Li W & Stanley ER (1991) Role of dimerization and modification...
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Báo cáo khoa học: A biophysical view of the interplay between mechanical forces and signaling pathways during transendothelial cell migration doc
... as Rac1 and Cdc42 reach peak activation, leading to cell respreading, elongation, and alignment in the direction of flow Both Cdc42 and Rac1 are required for cell elongation, whereas Rho and Rac1 ... nuclear factor-jB (NF-jB) activation, a mitogen-activated protein kinase cascade, and proteolysis leading to apoptosis Activation of the NF-jB pathway leads to recruitment and activation of IjB kinase ... mechanotransduction and mechanotransmission effects Mechanical properties of ECs It is believed that the mechanical state of the endothelium is extremely important in maintaining vascular homeostasis, and for...
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Báo cáo khoa học: Characterization of testis-specific serine–threonine kinase 3 and its activation by phosphoinositide-dependent kinase-1-dependent signalling doc
... rapid and strong activation of PKB (also known as c-Akt) [28] and this is mediated by phosphatidylinositol kinase (PtdIns3K) and PDK1 Thus A14 cells were transfected with HA-tagged TSSK3 and treated ... adaptors ⁄ effector(s) may be necessary for maximum activation and ⁄ or activation by PDK1 of TSSK3, as suggested for PKCf phosphorylation and activation by PDK1 [35] Thus we hypothesize that in ... with substitution of Ser5 and Ser6 to Ala and peptide 4(S4,6A), KRRASAYHV with substitution of Ser4 and Ser6 to Cys Oligonucleotides contained EcoRI overhang on 5¢ site and NotI overhang on 3¢...
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Báo cáo Y học: Requirement of caspase and p38MAPK activation in zinc-induced apoptosis in human leukemia HL-60 cells potx
... prior to the caspase activation (6 h) and induction of apoptosis (6 h) (Figs 3A,B and 4A) Moreover, SB203580, a specific inhibitor of p38MAPK, inhibited the activation of p38MAPK and the induction ... and p38 mitogen-activated protein kinases (p38MAPK) ERK1/2 are activated mainly by growth factors and are critically involved in the regulation of mitogenesis [28,29] On the other hand, JNK and ... inhibited the activation of caspases (Fig 4D) Z-Asp-CH2-DCB did not inhibit the activation of p38MAPK (Fig 4E) These data indicate that activation of p38MAPK is required for the caspases activation...
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Báo cáo khoa học: "Mechanical Translation and the Problem of Multiple Meaning" pdf
... [The two exceptions which occurred, по делу and цель в, were easily handled by separately listing дел in the form делу , and цел in the form цель ] and for over 90% of the three-word sequences ... (Ornshtein, the Kroutkov, and others, see also ) that the uncorrelated random function is not the velocity, and the acceleration, i.e., the force More precisely, it was assumed that the random force, remaining ... дел, сут, цел, по, в, о, and теори From these eight words it is possible to form 56 two-word sequences and 336 three-word sequences However, of these only 29 two-word and 106 three-word sequences...
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MECHANICAL DESIGN AND CONTROL OF THE PENDUBOT potx
... position and velocity data of the actual Pendubot and ysi is the output position and velocity data found by simulation runs θ is the vector of inertial parameters to be found and θlb and θub are ... System for Control Research and Education, "34th IEEE Conf on Decision and Control", New Orleans, Dec., 1995, submitted [11] Block, D J., and Spong, M W., "Mechanical Design and Control of the Pendubot, ... Appendix F for the mechanical drawings of the links and couplings To test our intuition on the length and weights of the links, we first performed simulation studies of the Pendubot and its controller...
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Rheological heterogeneity, mechanical anisotropy and deformation of the continental lithosphere pdf
... of these domains and the time interval between its development and reactivation are, however, crucial to its mechanical effect during subsequent deformation episodes Morgan and Ramberg (1987) ... temperatures, beneath cratonic domains (Grand, 1994; Polet and Anderson, 1995; Van der Lee and Nolet, 1997) This suggests that cratonic blocks have cold geotherms and, therefore, a high stiffness (Fig ... Babuska, 1981; Nicolas and Christensen, 1987; Mainprice and Silver, 1993) and is regarded as the main source of teleseismic shear wave splitting (e.g., Silver and Chan, 1988; Vauchez and Nicolas, 1991;...
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mechanical, thermal and environmental testing and performance of ceramic composites and components
... R., Ojard, G C., and Cairo, R R "Relationships of Test Methods and Standards Development to Emerging and Retrofit CFCC Markets," Mechanical, Thermal and Environmental Testing and Performance of ... Cataloging-in-Publication Data Mechanical, thermal, and environmental testing and performance of ceramic composites and components / Michael G Jenkins, Edgar Lara-Curzio, and Stephen T Gonczy, editors ... dedication and contribution of time and effort on behalf of ASTM Printed in Philadelphia, PA September 2000 Foreword This publication, Mechanical, Thermal and Environmental Testing and Performance...
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practical guide to the packaging of electronics thermal and mechanical design and analysis
... 34 Chapter where At and Aj are the areas of surfaces i and j, respectively, and /? ,and Pj axe the angles between the position-dependent normal vectors to surfaces i and j and a line of length ... shock and vibration Thermomechanical management is concerned with the impact of thermal loads on the mechanical behavior of the system In this work, we will set the foundation for thermal and mechanical ... are four topics that I categorize under packaging and enclosure design and analysis These are electromagnetic, thermal, mechanical, and thermomechanical analyses We will not cover electromagnetics...
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báo cáo hóa học: " The effects of powered ankle-foot orthoses on joint kinematics and muscle activation during walking in individuals with incomplete spinal cord injury" pptx
... compared to stepping with manual assistance A more thorough understanding of how mechanical assistance alters muscle activation patterns and kinematics in neurologically impaired subjects is important ... joint angles and footground contact, lower limb surface electromyography, pushbutton control signal, artificial muscle force and elastic band force We recorded bilateral ankle, knee and hip Page ... speed, trial condition and fidelity of the data We calculated the average standard deviation over the stride cycle (reported in Figures and 5) for each average profile and for each condition...
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báo cáo hóa học: " Differential regulation of Aβ42-induced neuronal C1q synthesis and microglial activation" pptx
... synthesis of other complement components Interestingly, C1q and, upon complement activation, C3 also can bind to apoptotic cells and blebs and promote ingestion of those dying cells [24-26] Elevated ... inhibits Aβ42 uptake and Aβ42-induced microglial activation and neuronal C1q production We have previously reported that C1q was detected in cells positive for neuronal markers and that microglial ... hippocampal section and averaged Image analysis further substantiated the reduction in Aβ uptake, C1q synthesis and microglial activation (Figure 1j) C1q gene expression at mRNA and protein levels...
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báo cáo hóa học: " Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment" ppt
... WMF, and WES conceived and designed the studies JAF conducted behavioral testing, and HY and JPW performed hippocampus dissections HDV, GVB, RMB executed and analyzed the experiments HDV and WMF ... Fcgr2b) and internalization of the protein, processing, and subsequent presentation by MHC II (for review see [30] and [31]) The MHC II complex consists of alpha and beta chains (Hla-Dra and Hla-Drb), ... moderate activation regardless of cognitive status, representing a 2.5-fold increase in activation compared to adults In DG of both aged intact and aged impaired rats, mild and moderate microglial activation...
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Báo cáo hóa học: "Alloying and Strain Relaxation in SiGe Islands Grown on Pit-Patterned Si(001) Substrates Probed by Nanotomography" doc
... areas on planar and patterned surface are marked in blue and red, respectively b Height distribution of islands grown on pit-pattern (red bars) and flat surface (blue) c, d Island aspect ratio ... properties of the islands, i.e., island size and shape, and their average composition The latter was evaluated by averaging the Ge content over all the matrix voxels of a given island From Fig 1c ... 1b, the mean height of coherent islands is similar, being (49 ± 6) nm and (54 ± 3) nm on the flat and patterned surfaces, respectively However, for a fixed island volume, V, the aspect ratio, r...
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Báo cáo hóa học: " Molecular Dynamics Simulation of Nanoindentation-induced Mechanical Deformation and Phase Transformation in Monocrystalline Silicon" potx
... 72 and nanoindentation-induced phase transformations during loading and unloading Both spherical and Berkovich indenters were considered Molecular ... effect of bond angle and covalent bonds has been shown to be particularly feasible in dealing with IV elements and those with a diamond lattice structure such as carbon, silicon, and germanium The ... metastable Si-III and Si-XII phases is strongly stress-dependent, different stress distributions induced by spherical and Berkovich indenters would result in different Si-III and Si-XII distributions...
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Báo cáo hóa học: " Influence of Surface Modified MWCNTs on the Mechanical, Electrical and Thermal Properties of Polyimide Nanocomposites" ppt
... duration and prolonged use between 200 and 350 °C without much deterioration in mechanical and other properties Polyimides are produced by the condensation reaction of an aromatic dianhydride and ... subsequently added and stirred at 70 °C for h After the reaction, the whole reaction mixture was filtered and the solid residue (MWCNTs-COCl) was washed several times with anhydrous THF and dried at ... The test was performed between 50 and 900 °C at a heating rate of 10 °C/min in air with a flow rate of 50 cc/min Mechanical Properties The tensile strength (TS) and Young’s modulus (YM) of the nanocomposites...
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Aircraft Systems Mechanical, electrical, and avionics subsystems integration, potx
... interactions and their inputs and outputs have propelled the exploitation of systems engineering by those in Aerospace and Defence The approach is not confined to those mechanical and electrical ... 1.7.2 Cable and Pulley System 1.8 High Lift Control Systems 1.9 Trim and Feel 1.9.1 Trim 1.9.2 Feel 1.10 Flight Control Actuation 1.10.1 Simple Mechanical/ Hydraulic Actuation 1.10.2 Mechanical ... Systems: Mechanical, electrical, and avionics subsystems integration, Third Edition Ian Moir and Allan Seabridge © 2008 John Wiley & Sons, Ltd ISBN: 978-0-470-05996-8 Aircraft Systems Mechanical, ...
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