... the subunit of VnfA bind the single Fe -S cluster A possible scenario is that two of three cysteine residues (Cys15 and Cys8 or Cys10) bind the Fe -S cluster andthe remaining residue binds the ... inthe N-terminal GAF domain Because a single residue gap between Cys8 and Cys10 is unusual in ligands for a single Fe -S cluster, it is unlikely that all the N-terminal cysteine residues inthe ... activity assays for cysteine variants of Strep-VnfA indicate that the N-terminal cysteine residues are plausible candidates for the ligands of the Fe -S cluster Thus, the locus of the Fe -S cluster should...
... gender-neutral business and investment laws to investigate attitudes, procedures for opening and closing businesses, and laws outside business and commerce, assessing whether such factors have gendered ... entrepreneurs hig h low Easiest to business 2nd quintile 3rd quintile 4th quintile Hardest to business Source: Doing Business database and Enterprise Surveys Note: Relationships are significant at the ... to start new businesses and how many succeed, as are data on the impact of barriers to starting, operating, and closing a business It is thus impossible at present to say whether there are so...
... the proof All authors conceived of the study, and participated in its design and coordination All authors read and approved the final manuscript Competing interests The authors declare that they ... Hyers-Ulam stability of Jensen s equation In 1998, Jung [16] investigated the Hyers-Ulam stability for Jensen s equation on a restricted domainIn this section, we prove a local Hyers-Ulam stability ... MS: Fuzzy stability of the Jensen functional equation Fuzzy Sets Syst 159, 730–738 (2008) doi:10.1016/j.fss.2007.07.011 Mirmostafee, AK, Moslehian, MS: Fuzzy versions of Hyers-Ulam-Rassias theorem...
... Unlike the Wigner distribution, the oversampling intimedomain is not necessary since the aliasing components will be removed inthe same way as the cross-terms More details about the Smethod ... the first summation includes autoterms, while the second one includes cross terms Since the cross-terms contribute in watermark detection, they should be included in other existing detectors structures ... EURASIP Journal on Advances in Signal Processing The detector responses must satisfy the following: STFTxw (t, ω) · STFTwkey (t, ω) > T, coefficients, inthe presence of cross terms inthe timefrequency...
... y axes; that is, the field in free space is transverse This is exactly what is observed inthe Fresnel–Arago interference equations Thus, inMaxwells theory this result is an immediate consequence ... the highly successful Fresnel theory with Maxwells theory The only difference between the two theories was that in Fresnel s theory the wave equation was the starting point, whereas Maxwells ... conducting dielectric We can now solve MaxwellsequationsThe result is remarkable and was the primary reason for Maxwells belief inthe validity of his equationsIn order to this, we first use the...
... marked increase in those diseases, suggesting the presence of HIV, can first be observed inthe main hospital in Kinshasa during the later 197 0s Thus HIV had existed as a rare disease in western ... disease was first recognised there, in 1983, it had already spread so widely inthe general heterosexual population as to be almost impossible to stop The first careful surveys in Kinshasa inthe ... Africans by displaying modernity and internationalism, stressing individualism andthe nuclear family, condemning corruption, and offering enticing prospects of success Rural pentecostalism, likewise,...
... highest to the lowest as follows: Strategy Class-shifts Intra-system-shifts Structural-shifts Unit-shifts Inthe data, the strategy “Class-shifts” stays on the first rank by appearing 39 times with ... Vietnamese to English in Trinh Cong Son s songs - Investigate the linguistic and non-linguistic factors influencing the choice of using each strategy in translating the lexicon and phrases and sentences ... Strategy Structural-shifts Class-shifts Unit-shifts Intra-system-shifts In this part, each strategy with examples will be presented and discussed 4.3.1 Structural – shifts These are amongst the most...
... using standard splicing techniques (usually mass splicing) with splices stored in standard splice closures Key FDH Capabilities – and Innovations The FDH enclosure provides a crucial craft interface ... fibers As each subsequent splitter was installed, it was spliced to feeder fibers staged in splice trays Splicing consumes valuable time, and adds costs to service turn-up Earlier improvements included ... parking lots required for pigtail outputs In essence, splitter outputs time share” parking lots; as the outputs of the initial splitter modules are placed into service, the parking lots associated...
... however, this gap has been closing in recent years due to decreasing numbers of men smoking and increasing numbers of women smoking in certain countries In addition, smoking-associated deaths among ... circulatory system, 135.5 of malignant neoplasms, 35.5 from diseases of the respiratory system, 22.3 from external causes (injury and poisoning), 15.4 from diseases of the nervous system and sensory ... disease of the circulatory system is cerebrovascular disease (stroke) Stroke is defined by the WHO as the interruption of the blood supply to the brain, usually because a blood vessel bursts...
... Ne-carboxymethyl-lysines and Ne-carboxyethyl-lysines and pentosidine) being known to accumulate with age on tissue proteins, and at an increased rate in LDL and atherosclerotic lesions in people with diabetes ... lesions [30]), did not result in significant cellular sterol accumulation This is in contrast to the results of a previous study, in which a twofold increase in cholesteryl ester synthesis was observed ... for days is recognized by macrophage scavenger receptors, but results in decreased intracellular cholesteryl ester synthesis in comparison to controls [33] This is in contrast to the situation...
... musculoskeletal problems and central nervous system illnesses Illnesses such as osteoporosis,49 musculoskeletal problems and central nervous system illnesses like Alzheimer and/ or dementia50 are linked to ... consumption of alcohol and drugs increases drastically among women and girls, which poses serious threats to their physical and psychological health Research and statistics in Sweden as well as ... pornography and sexist advertising; violence in institutional settings like hospitals and care institutions, prisons or reception centres for asylum seekers; prostitution; trafficking in women; and male...
... A “Hands- Off” U .S Policy It has been U .S policy at least since 1951 to give the Saudis a pass on human rights issues inthe interest of maintaining strong ties on other matters perceived as more ... because it has retained Bush s policy of refusing to deal with Hamas Iraq The Saudis, having opposed the U .S invasion, distanced themselves from the results of it In their view, the Shia-dominated ... rather than as an enemy, which is the course the administration elected to follow The Saudis’ Resentment Lingers Still, the dissonance inthe relationship was not hard to discern The Saudis seethed...
... constructing it, has its origins inthe notions of granularization as used in a paper of I.Z Ruzsa andthe author [9] Inthe present context things look rather different however and, inthe absence ... Varnavides based on Roth s theorem tells us that a dense subset of ZN contains lots of 3APs We will adapt his argument in a trivial way to show that the same is true of set-like measures The arguments ... follows The almost-primes are eminently suited to applications of sieve techniques To keep the paper as self-contained as possible, we will follow Gowers [8] and use the arguably simplest sieve,...
... domains: an N -domain and two ATP-binding domains referred to as the D1 and D2 domains Interestingly, deletion of the N -domain from ClpA not only abolishes binding of the adaptor protein, ClpS, ... casein, binding to the tyrosine residues inthe hexameric pore of ClpA is sufficient for substrate translocation to occur; however, in other cases such as SsrA-tagged protein substrates, binding ... mechanistic understanding of the ClpAP machine is based largely on the use of model proteins such as casein and GFP–ssrA Previous studies have demonstrated that a ring of tyrosine residues located in...
... occur within isolated NBDs, suggesting that such domains are a useful model system for analysing nucleotide binding inthe intact transporter Structural investigations of bacterial NBDs have revealed ... chain to the nucleotide-binding pocket [3] We describe the engineering, expression and purification of single-cysteine-containing proteins comprising either the C-terminal NBD or the N-terminal ... alter the accessibility and reactivity of this cysteine Therefore, the purified singlecysteine-containing fusion proteins were examined for their ability to bind N-ethylmaleimide The single cysteine...
... bottom-line business these days Its popularity has soared to the point that it generates $9 billion in annual revenues and dominates the country s sports conversation 365 days a year Nothing tops it And ... notion and nuance and drive them into the backs of your eyeballs Interest was still driven by wins and losses, not by salaries, uniform colors, personalities, commodities, and advertising campaigns ... noise from those days still resonated inthe early ‘6 0s The SMU Mustangs, Pop s first love as a fan, had sold out the Cotton Bowl inthe ‘4 0s and early ‘5 0s, and continued to draw well Texas and...
... the specific bridging versus terminal cysteine residues is possible in this 113Cd-decoupled spectrum, and a nearly complete assignment of the cysteine residues inthe 2D spectrum has been FEBS ... by raising the pH inthe presence of stoichiometric amounts of Zn2+ The top spectrum of Fig shows that the Zn4a species is the sole species formed inthe reconstitution process In all the spectra, ... derivative-shaped CD signal and a distinct NMR spectrum Despite the highly conserved positioning of the cysteine residues inthe mammalian sequence of metallothionein andthe structural consistencies, the...
... PESTfind score [29] anddomain location NA indicates, for SOCS-2, -4 and -6, that no PEST motif was predicted for these proteins Protein SOCS1 SOCS2 SOCS3 SOCS4 SOCS5 SOCS6 SOCS7 CIS PESTfind score ... Domain characterization of SOCS3 N-terminal SH2 SOCS box P 45 185 socs1 socs2 socs4 socs5 socs6 socs7 P P socs3 225 P P P CIS Fig The suppressor of cytokine signalling (SOCS) family of proteins ... the SOCS proteins Expression of the SOCS proteins is induced directly by STAT binding to the appropriate promoters Rapid destruction of the SOCS protein is also necessary, once signalling has...
... readings of the book and excellent work in preparing figures and tables throughout the book I was also fortunate to have the able assistance of Melissa Hawkins inthe final stages of work on this ... versus 4.7%), and professional industries (17.1% versus 35.3%) and are less likely to work in manufacturing (23.1% versus 11.4%) and personal services (14.6% versus 5.3%).9 With these changes ... births in sampled states and 50% of births in all other states ††† Includes all persons of Hispanic origin of any race Source: Ventura SJ, Martin JA, Curtin SC, Matthews TJ, Park MM Births: final...
... especially the poor and those living in rural areas, and decrease disparities within countries ■ Improve quality of care by establishing standard protocols, setting up systems for monitoring and ... conservative social mores that discourage extramarital sex also discourage open discussion of sexuality, condoms, STIs, and HIV/AIDS But open, frank dialogue is key to addressing STIs and other ... deploying skilled health professionals, and securing essential equipment and drugs It is also important to improve managerial capacity at all levels ■ Develop sustainable financing mechanisms, possibly...