... Biosciences), or anti-b actin (Sigma) antibodies; or rabbit polyclonal anti-MMP2, anti-Akt, anti-phosphoAkt (ser473/thr308), anti-phosphoGSK3b (ser9), anti-b-catenin, anti-phosphobcatenin (ser 33,37/thr ... elucidate further its important cell regulatory function(s) as well as its potential as a therapeutic agent Abbreviations APF: antiproliferative factor; as-APF: asialo-APF; CKAP4: cytoskeletonassociated ... tyr: tyrosine; thr: threonine; siRNA: small interfering RNA Acknowledgements The authors thank Eunice Katz for her assistance with the preparation of this manuscript This material is based upon...
... in breast cancer, with homozygote patients being afflicted with more aggressive cancers [6] , rheumatoid arthritis where a large panel of SNPs contribute to specific point or loci mutations related ... study and detect protein biomarkers For example, the human chrionic gonadotropin and activated leukocyte cell adhesion molecule are biomarkers for trophoblastic, breast, and epithelial tumours, ... alleviated metastatic risks through the down regulation of the C-C cytokine receptor type [36] The HER2/neu protein, being over-expressed in 10-34% of the invasive breast cancer cases, has been a prime...
... a ribose SUGAR with a “missing oxygen” (that’s the de-oxy part) And it’s found in the nucleus of eukaryotic organisms How does DNA code for protein synthesis? First-what is “protein synthesis”? ... letters are put together) produce messenger RNA sequence codes The messenger RNA leaves the nucleus and attaches to a ribosome in the cytoplasm Transfer RNA brings amino acids to the ribosome...
... Annual Meeting of the Association for Computational Linguistics and the 10th Conference of the European Chapter of the Association for Computational Linguistics, pages 188–195 Toulouse, France,...
... releases/2003/pr27/en/ Ferlay J, Autier P, Boniol M, et al Estimates of the cancer incidence and mortality in Europe in 2006 Ann Oncol 2007;18:581-92 Davila RE, Rajan E, Baron TH, et al ASGE guideline: colorectal ... Paradigm models of colorectal cancer, breast cancer, and chronic myelogenous and acute lymphoblastic leukaemia J Exp Clin Cancer Res.2005; 24(4):505-14 O'Connell JB, Maggard MA, Ko CY Colon cancer survival ... Slack GW, Wizniak J, Dabbagh L, et al Flow cytometric detection of ZAP-70 in chronic lymphocytic leukemia: correlation with immunocytochemistry and Western blot analysis Arch Pathol Lab Med.2007;...
... Denny CT (1997) Biology of EWS ⁄ FLI and related fusion genes in Ewing’s sarcoma and primitive neuroectodermal tumor Curr Top Microbiol Immunol 220, 143–150 Rauscher FJ III (1997) Chromosome translocationmediated ... pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR ⁄ ABL-mediated leukemogenesis EMBO J 15, 4442–4455 Bertolotti A, Lutz Y, Heard DJ, Chambon P & Tora L (1996) hTAFII68, ... & Darnell RB (2001) Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function Cell 107, 489–499 Zanotti KJ, Lackey PE, Evans GL & Mihailescu MR (2006) Thermodynamics...
... Sky RTK [18] Also, a novel neuroprotective effect was revealed for protein S in a mouse study of stroke, in which administration of protein S protected ischaemic neurons both in vivo and in vitro ... Myeloid and erythro-megakaryocytic leukaemias Oesophagus Gastric Experimental – cell transformation Experimental – haematopoietic cell expansion Acute myeloid leukaemia Myeloma cells Experimental ... JP, Frye RA, Cogswell PC, Neubauer A, Kitch B, Prokop C, Espinosa R, Le Beau MM, Earp HS & Liu ET (1991) axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel...
... the classifier of Cui et al (2007) is based on soft patterns but also on a bag-of-word relevance heuristic However, the relative influence of the two methods on the final performance is not discussed ... semantic relations from a basque monolingual dictionary using constraint grammar In Proceedings of Euralex Claudia Borg, Mike Rosner, and Gordon Pace 2009 Evolutionary algorithms for definition extraction ... and quasi-cycles to disambiguate dictionary glosses In Proceedings of the 12th Conference of the European Chapter of the Association for Computational Linguistics (EACL 2009), pages 594–602, Athens,...
... (3): 154165 Alejandro Figueroa and G¨ nter Neumann 2006 Lanu guage Independent Answer Prediction from the Web In proceedings of the 5th FinTAL, Finland Eugenie Giesbrecht and Stefan Evert 2009 Part-ofspeech ... by choosing the queries from a set of ten themes The queries covered definition questions like EEUU and NLF, questions about persons like Justin Bieber, David Beckham, Pete Best, Clark Kent, and ... supported by grants from the German Federal Ministry of Economics and Technology (BMWi) to the DFKI Theseus projects (FKZ: 01MQ07016) TechWatch–Ordo and Alexandria4Media #Question v.good good avg poor...
... and several other languages, which have no explicit word boundaries, than for Engllsh and many European languages (Miyazald, 1983) (Ohyama, 1986) (Abe, 1986) English text reading has the advantage...
... in Parkinson’s disease NeuroReport 10, 2273–2276 10 Head MW & Goldman JE (2000) Small heat shock proteins, the cytoskeleton, and inclusion body formation Neuropath Appl Neurol 26, 304–312 11 Martin ... Medical Research Council of Australia and the Australian Research Council References de Jong WW, Leunissen JAM & Voorter CEM (1993) Evolution of the a-crystallin ⁄ small heat-shock protein family ... Heat-shock proteins and molecular chaperones: implications for pathogenesis, diagnostics and therapeutics Int J Clin Lab Res 25, 59–70 Bose S, Ehrnsperger M & Buchner J (1999) Mechanisms of ATP-independent...
... design is shown in Fig 1A [4] As shown, the pri-miRNAs based on miR155 are processed in the nucleus by Drosha to set up transport of pre-miRNAs to the cytoplasm, where they are further processed...
... acids are equally unproblematic because the amino protons of amino acids exchange too rapidly at neutral pH to yield a signal observable in [15N]-HSQC spectra It is thus possible to obtain clean ... cell-free synthesis of selectively 15 N-labelled proteins for rapid analysis by NMR spectroscopy Eur J Biochem 271, 4084–4093 19 Klammt C, Lohr F, Schafer B, Haase W, Dotsch V, ¨ ¨ ¨ Ruterjans ... Bernhard F (2004) High¨ level cell-free expression and specific labeling of integral membrane proteins Eur J Biochem 271, 568–580 20 Morita EH, Shimizu M, Ogasawara T, Endo Y, Tanaka R & Kohno T (2004)...
... the unexpected discovery by genome sequence analysis of a complete urea cycle in the diatom T pseudonana appeared to imply that a more complex regulatory network may control nitrogen metabolism ... diatoms Only recently the first two sequences of diatom NR genes have become available from T pseudonana [6] and P tricornutum [18], yet in neither organism has NR gene expression been analyzed ... which exhibited 69% and 77% sequence identity with the corresponding NR sequence regions from T pseudonana and P tricornutum, respectively Screening of the C fusiformis genomic DNA library, using...
... R., Rentrop, M & Maelicke, A (1997) Neuronal cell nuclear factor: a nuclear receptor possibly involved in the control of neurogenesis and neural differentiation Eur J Biochem 249, 826–837 Henikoff, ... during neural development in vitro Eur J Cell Biol 77, 323–337 59 Marusich, M.F., Furneaux, H.M., Henion, P & Weston, J.A (1994) Hu neuronal proteins are expressed in proliferating neurogenic ... protein kinase C (PKC) substrate GAP-43 is already expressed in neural precursor cells, colocalizes with PKCg and binds calmodulin Eur J Neurosci 11, 503–516 46 Harlow, E & Lane, D (1988) Antibodies...
... Ministry of Education, Science, Sports, and Culture, Japan PKR interacts with ASK1 (Eur J Biochem 269) 6131 REFERENCES Meurs, E., Chong, K., Galabru, J., Thomas, N.S.B., Kerr, I.M., Williams, B.R.G ... endogenous PKR in these cells were confirmed by Western blotting (Fig 1C, 6128 T Takizawa et al (Eur J Biochem 269) Ó FEBS 2002 Fig PKR interacts with ASK1 (A) Cytoplasmic localization of ASK1 ... of ASK1 (lane in Fig 3) (an average of 3.4fold increase) Ó FEBS 2002 PKR interacts with ASK1 (Eur J Biochem 269) 6129 Fig Effect of dominant negative mutant of PKR (PKR-KR) on ASK1-induced apoptosis...
... and we discuss some quantitative results The NERD application is accessible online at http://nerd eurecom.fr It requires to input a URI of a web document that will be analyzed and optionally an ... one or more evaluations to see the metrics that are computed for each service in 13 http://nerd.eurecom.fr real time Finally, the application contains a help page that provides guidance and details ... dbpedia org / r e s o u r c e / Tim berners lee ” , ” n e r d T y p e ” : ” h t t p : / / n e r d eurecom f r / ontology # Person ” , ” s t a r t C h a r ” : 30 , ” endChar ” : 45 , ” confidence...
... interactions) were directly between residues of the protein C Gla domain (Phe4, Gla7, Leu8, Gla25 and Gla29) and EPCR (Leu82, FEBS Journal 272 (2005) 97–108 ª 2004 FEBS R J S Preston et al Arg87, Gln150, ... were also detected between lysophosphatidylserine and residues of the x-loop, including Phe5, Leu6 and Gla7 Furthermore, the glycerophosphate backbone was shown to interact with a basic region ... has been shown to mediate signal transduction pathways and contribute to APC antiapoptotic and neuroprotective activities [16,52] This nonanticoagulant activity is entirely reliant on the APC–EPCR...
... (ii) string similarity in terms of Levenshtein distance between term candidates For evaluation, Eurovoc (Steinberger et al., 2002) was used Tables and show the performance figures of the mapper ... The research within the project ACCURAT leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013), grant agreement no 248347 Sadaf Abdul-Rauf ... comparable corpora to improve SMT performance EACL 2009: Proceedings of the 12th conference of the European Chapter of the Association for Computational Linguistics, Athens, Greece, 16-23 F-measure...