... obsessed about
scoring in games, and inthe backseat of a car. At the point when
boys and girls begin deciding the trajectories of their careers, girls
start to lose interest in pursuits that ... Brizendine,
And in loving memory of
Louise Ann Brizendine
T he F emale B rain
machinery she needs to live outside her mother’s body. But the major-
ity ofthe brain development that determines ... response. The girls will think that if they do
it just right, they’ll get the reaction they expect. It’s the same kind of
instinct that keeps a grown woman going after a narcissistic or other
-
wise...
... protein
domain (E3int) representing the interface domain (resi-
dues 343–470) of B. stearothermophilus E3. The use of
the engineered E3int domain (27 kDa as the dimer)
was introduced because the high ... investigate the basis ofthe interaction of E2p with E3 inthe assem-
bly ofthe pyruvate dehydrogenase multienzyme complex of Bacillus stearo-
thermophilus. Thirteen ofthe 55 amino acids inthe PSBD ... determined here (see
above) are probably due to the use of uniformly
15
N-labelled PSBD and the inclusion of additional resi-
dues inthe construct at the N-terminus ofthe domain.
In particular, the...
... Vietnamese. At the beginning of each
interview, the students were explained clearly, explicitly and unambiguously about the nature of
the study. During the interview, the researcher modified the questions ... ofthe teachers often used the same six steps in
organizing group work as these might be the basic steps needed for it. Inthe interview, almost
all ofthe teachers thought that providing the ... Additionally, the current body of research
mainly focuses on the product of group work implementation. Therefore, the researcher wants to
investigate the use of group work in teaching speaking of English...
... exceed the lesser of 10% ofthe value of
the gift and $75, then the value ofthe advantage is considered to be zero. For
example, if the price to attend the benefit dinner is $200 and the value of ... to
plan.
Dinner, gala or social - Coordinate an evening of dinner and dancing in support
of HSFM. Benefit dinners are great for rewarding employees and for promoting
their work inthe community. ... services received in exchange for a gift as
the Advantage. Inthe above example the advantage is the value ofthe dinner,
i.e. $40.
In situations where the cost or portion ofthe cost is covered...
... oxygen of
the main chain at Asp266 was bound to amino groups of
main chain of Tyr269 and Ala270 by hydrogen bonds. The
interactions should maintain the structure ofthe C-terminal
region. Inthe ... region on the opposite side of
the N-terminal region on the molecular surface. Inthe wild-
type enzyme, the side chain of Asp266 interacted with the
amino group ofthe main chain at Glu268. The oxygen ... autolysis in the
N-terminal region and/or the C-terminal region [12,13].
We hypothesized that the divergence ofthe properties of
ALP I from the alkaline subtilisins might depend on the
structure of the...
... CaM-binding
domains, and contains at least one conserved potential
CaM-binding motif [46]. Additionally, the binding of
CaM at the C-terminus and the binding of NADPH at
the extreme N-terminus ... including the dehydrogenase domain. Spe-
cific binding ofthe FNR is mediated by a unique series
of proline/serine-rich repeat motifs located in the
C-terminus. For the integration into the Tic ... N-terminus, anchoring it inthe IEM, whereas the
C-terminus ofthe protein projects into the stroma
(Fig. 1) [34]. Two motifs can be located inthe C-termi-
nal half ofthe stromal domain: (a) the...
... indicating that interaction with Smac is not
required with respect to the role of HSP70 inthe inhi-
bition ofthe release of Smac and apoptosis.
The role ofthe ATP-binding domain of HSP70
in ... showing
immunoreactive bands ofthe expected sizes (Fig. 4B).
Next, whether the protective potency of HSP70 would
be annulled by deletion ofthe ATP-binding domain or
the peptide-binding domain ... transfected
C2C12 cells. Furthermore, there was no direct interac-
tion between HSP70 and Smac proteins, and the
ATP-binding domain of HSP70, rather than the pep-
tide-binding domain, was essential for...
... with the biosyn-
thetic pathway of neral in Car. lactis (Fig. 1). A previ-
ous study has also shown that the oxidation of
geraniol is one ofthe key steps inthe production of
neral [12]. The ... that of other ADHs [22,30–32].
The highly conserved sequences of zinc-binding and
NAD
+
-binding sites as compared to other ADHs
suggest that Car. lactis GeDH belongs to the med-
ium-chain dehydrogenase ... structural maintenance. The glycine-rich region
(position 204–209, GLGGIG) is also conserved in
Car. lactis GeDH (Fig. 5), and has been found in the
NAD
+
-binding site in ADHs [34]. The absence of the
probable...
... The Cleveland Era: A Chronicle ofthe New Order in Politics
5
enlisted in their support. But those interests are inthe main the
interests of getting or keeping the patronage ofthe government. ... question ofthe fishery rights ofthe two governments and
The Cleveland Era: A Chronicle ofthe New Order in Politics
33
On the 2nd of March, a minority report was submitted, making the
point of ... message opened with the statement that “ever since the
beginning ofthe present session ofthe Senate, the different heads of
the departments attached to the executive branch ofthe government
have...
... reducing
the NADPH concentration by half, or increasing it
twofold, had no in uence on the yield of GDP-Fuc.
Furthermore, reduced conversion ofthe intermediate
was observed inthe absence of dithiothreitol. ... Amsterdam, the Netherlands), which were
grown overnight in 10 mL Luria–Bertani medium containing
kanamycin and chloramphenicol (also containing ampicillin
in the case of double transformation). Inthe ... (alternatively spliced form of GMD-1), gmd-2 and
ger-1. The amounts of cDNA used inthe PCRs were normalized on
the basis ofthe intensity of actin transcripts.
GDP-fucose biosynthesis in invertebrates S....
... Yap1
to the GSH1 promoter could be repressed by Cbf1, a
DNA-binding protein that binds to elements in the
vicinity of Yap1 binding site [52]. Alternatively, the
increased reducing power of tsa1 ... that Yap1 is
retained inthe nucleus inthe presence of H
2
O
2
and
thereby it interacts with the target genes [11,46,47].
This retention is dependent ofthe oxidation of Yap1
cysteine residues by ... accumulation in
the nucleus of cells shifted from glucose to glycerol,
otherwise observed, inthe presence of glutathione
externally added.
Another striking point inthe adaptation of cells
to...
... result-
ing in a chimeric protein designated gp130c.Inorderto
investigate the role ofthe membrane-proximal domains of
gp130 in receptor activation, the FNIII-domain deletions
were introduced into the ... domain inthe membrane-proximal part of gp130
leads to a shift ofthe receptor areas involved in ligand
binding closer to the membrane, resulting inthe inability of
the receptor chains to form ... membrane-proximal
domains of gp130 is limited to ensure the correct spacing
between the CBM and the membrane, each ofthe domains
was replaced by the corresponding domain ofthe GCSFR.
The replacement...
... taurine uptake in NIH3T3 mouse
fibroblasts is linear within the initial 20 min following the
addition of
14
C-labelled taurine. Using taurine uptake
within the initial 20 min in NaCl medium containing
extracellular ... and the protein content. The taurine inux (nmolặ
gprotein
)1
ặmin
)1
) w as estimated as the slop e o f the cellular
taurine uptake plotted vs. time.
Estimation ofthe taurine efflux
Taurine efflux ... b-alanine) are
potential inhibitors ofthe active uptake [7]. The data shown
in Fig. 1 and summarized in Table 1 indicate that the i nitial
taurine uptake is reduced inthe presence of b-alanine
(Fig....
... located at the
C-terminal end ofthe linker region between the LD and the
PSBD, just before the beginning of helix 1 inthe PSBD [6].
Preceding Met131 inthe linker sequence, there is a series of
hydrophobic ... higher than that ofthe wild-type PSBD. In
fact, the side-chains of lysine and arginine are significantly
different, both in length and inthe point (lysine) and
delocalized (arginine) positive charge. ... hydrogen bonds. These properties account for the
favoured occurrence of arginine residues at binding inter-
faces. Indeed, in a database analysis ofthe contributions of
individual amino acid residues...
... genes to test the importance of the
conserved Glu residues inthe EX
7
E motif of these proteins
by the stringent criterion of their ability to support cell
growth. Our results indicate that ... importance
in vivo
of conserved glutamate residues
in the EX
7
E motif retaining glycosyltransferase Gpi3p,
the UDP-GlcNAc-binding subunit ofthe first enzyme
in glycosylphosphatidylinositol assembly
Zlatka ... data
showing retention of function of various key mutants in vivo
render a demonstration of misfolding, instability, or mislo-
calization ofthe protein, or of impaired complex formation
by the protein,...