liver regeneration and the atrophy hypertrophy complex

Báo cáo Y học: Changes in ultrastructure and the occurrence of permeability transition in mitochondria during rat liver regeneration ppt

Ngày tải lên : 24/03/2014, 04:21

... in the swelling medium and the absorbance of the mitochondrial suspension as a function of time was monitored either in the absence or in the presence of CsA (1 lM), the speciﬁc inhibitor of the ... cristae-rich, and with an electron-dense matrix Quantitation of normal and altered mitochondria in control liver and in liver at 24 and 96 h after PH was performed The majority of liver mitochondria ... decrease in the activity of the mitochondrial marker enzymes GDH and mAAT in the total liver homogenate at 24 h after PH (15% and 24% decrease for GDH and mAAT, respectively) Moreover, in the hepatocytes...

9
494
0

Báo cáo khoa học: "The combined effect of erythropoietin and granulocyte macrophage colony stimulating factor on liver regeneration after major hepatectomy in rats" pot

Ngày tải lên : 09/08/2014, 03:21

... of the study, and participated in its design and coordination and helped to draft the manuscript NC, TA and DN conducted the experiments TT and FG participated in the design of the study and ... the extent of regeneration [18] In addition, they are have already been widely used for the study of liver regeneration and in particular for the study of the effects of EPO on liver regeneration ... affect liver regeneration after partial hepatectomy in mice [23] During liver regeneration the expression and activity of proapoptotic pathways is inhibited and after massive liver resection the...

6
292
0

Báo cáo y học: "Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy"

Ngày tải lên : 31/10/2012, 15:37

... of gastric atrophy [18] Table shows the age-sex-adjusted ORs of the Gab1 and the combinations of PTPN11 and Gab1 genotypes for gastric atrophy among seropositive healthy controls The OR of G/A+A/A ... of cancer In summary, the Gab1 A/A was associated with the low risk of H pylori infection while the G/A and A/A genotypes together may increase the risk for gastric atrophy The biological mechanism ... with seropositive atrophy The ORs of the G/A and A/A for gastric cancer was 1.05 (95% CI 0.63-1.74) and 1.05 (95% CI 0.27-4.07), respectively Table The Gab1 genotype frequency and ORs for gastric...

6
541
0

Emergent Complexity, Teleology, and the Arrow of Time

Ngày tải lên : 01/11/2013, 07:20

... reducing the density and pressure of the gas adjacent to the piston The upshot is that the work done by the gas on the piston during the outstroke is somewhat less than the work done by the piston ... understand If the piston moves fast when it compresses the gas, there will be a tendency for the gas molecules to crowd up beneath the piston As a result, the pressure of the gas beneath the piston ... done by the piston on the gas during the instroke The overall effect is a net transfer of energy from the piston to the gas, and the temperature, hence the entropy, of the gas rises with each...

19
466
0

Tài liệu Báo cáo khoa học: The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase) pptx

Ngày tải lên : 19/02/2014, 16:20

... functional complex I (Fig 3B, right panel) The signal from the 18 kDa subunit of complex I (NDUFB6) served as another identiﬁcation of the complex at the position of the histochemical stain in the left ... supercomplexes and the effect of the absence of intact complex I, but the results are too preliminary in this regard Heterologous expression of the ESSS-HA subunit The localization of the ESSS subunit in the ... mitochondria from the transfected cells Left panel: the bands represent anti-MWFE Ig bound to complex I; the two lower bands represent complex II and its dimer, detected by antiserum against the SDHC...

9
622
0

Tài liệu Báo cáo khoa học: Long-distance interactions between enhancers and promoters The case of the Abd-B domain of the Drosophila bithorax complex pdf

Ngày tải lên : 20/02/2014, 01:20

... only the reporter gene situated on the same side, relative to the boundary, of the construct However, when the combination of the PTS and the boundary is placed 3¢ to one of the reporter genes, the ... outside the region deﬁned by the promoters of the two reporter genes (3¢ to one of them, Fig 4, bottom), the PTS is able to overcome the enhancer blocking effect of the boundary, and restricts the ... the Abd-B promoter and the iab regions [13] The unusual properties of the tmr led to the hypothesis that it may be involved in a process that normally targets the iab regions to the Abd-B promoter...

7
719
0

Tài liệu Báo cáo khoa học: Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase Structure of the reduced enzyme-progesterone complex and the roles of residues Tyr186, His181 and His184 pdf

Ngày tải lên : 20/02/2014, 02:21

... Properties of the H181A and H184A enzymes The structure of PETN reductase solved in complex with prednisone, progesterone, 1,4-androstadiene (Fig 1A) and 2-cyclohexen-1-one indicate that these ligands ... and are bound between the progesterone and the protein (Fig 7A) In comparison to the oxidized structures, the FMN isoalloxazine ring is less planar, with both the N5 atom and the C8-C7 methyl groups ... s, and indicate re-oxidation of the ﬂavin and the formation of the hydride-Meisenheimer complex of TNT (C) As for panel B except the spectral changes are recorded over an extended time period and...

12
603
0

Báo cáo khoa học: NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B–NS3 protease ppt

Ngày tải lên : 07/03/2014, 02:20

... resonances of the complex with were assigned using NS2B–NS3pro, whereas the 3D NMR experiments of the complexes with and employed the WNV NS2B–NS3pro(K96A) mutant The resonance assignments of the complexes ... sites Because the NMR spectra of the protease complexes with and were very similar, both compounds must bind in the same way Therefore, we only studied the binding of the nonsymmetric and more soluble ... that binds to the substrate-binding site of the protease In the ﬁrst experiment, we compared the 15N-HSQC spectra of WNV NS2B–NS3pro(K96A) in the presence of and in the presence of the Bz-nKRR-H...

12
451
0

Báo cáo khoa học: Functional association of the AAA complex and the peroxisomal importomer potx

Ngày tải lên : 07/03/2014, 12:20

... supports the idea that Pex1p and Pex6p form a complex with Pex15p at the peroxisomal membrane The core complex of Pex1p, Pex6p and Pex15p is associated with the importomer The recent discovery of the ... of the membrane-bound AAA complex and the importomer Therefore, the protein complexes isolated with protein A fusions of Pex1p, Pex6p and Pex15p were tested for the presence of peroxins of the ... association of the membrane-bound AAA complex and the importomer The ﬁndings that Pex1p, Pex6p and Pex15p copuriﬁed with several peroxins raised the question whether they all assemble into a common complex...

12
458
0

Báo cáo khóa học: Disruption of the interaction between the Rieske iron–sulfur protein and cytochrome b in the yeast bc1 complex owing to a human disease-associated mutation within cytochrome b potx

Ngày tải lên : 07/03/2014, 15:20

... ISP and the extramembranous cd2 helix of cytochrome b are important for maintaining the structure of the hinge region and, by consequence, the movement of the headgroup and the integrity of the ... enzyme with their ISP in different conformations The mutation G167E could distort the hinge region of the ISP and hinder the movement of the headgroup Mutations in the hinge region of the ISP, which ... the loss of the ISP, which suggested that the mutation weakened the binding of the subunit to the complex [14] The replacement of residues ADV with PLP was less deleterious The bc1 complex showed...

7
498
0

Báo cáo khoa học: DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond pptx

Ngày tải lên : 14/03/2014, 22:20

... functions and ⁄ or protein complexes (Fig 3A) In the following paragraphs we select a few examples from these clusters and describe their functions and the possible roles of LC8 in the complexes ... determinants of the motif are the most conserved Gln0, the ﬂanking Thr+1 and Thr)1 residues and Asp)4 (Fig 1C) We depict 11 residues both on the logo and in Tables and since the binding site ... homodimeric LC8–target complexes interact via their ligands (E) Such an interaction between two ligandbound LC8 complexes via antiparallel b-strands of the ligands has been observed hitherto only as...

17
573
0

Báo cáo khoa học: "Smart Paradigms and the Predictability and Complexity of Inﬂectional Morphology" docx

Ngày tải lên : 24/03/2014, 03:20

... to learn the repetitive details of a finite automaton We define the code complexity as the size of the abstract syntax tree of the source code This size is given as the number of nodes in the syntax ... 2541 6885 ers Following the definitions of Section 3, we have counted the the complexity of the smart paradigm definitions for nouns and verbs in the different languages in the GF Resource Grammar ... (“car–cars”) and nyckel–nycklar (“key–keys”) are traditionally both treated as instances of the second declension, with the plural ending ar and the contraction of the unstressed e in the case of...

9
467
0

PERIPHERAL NEUROPATHY - A NEW INSIGHT INTO THE MECHANISM, EVALUATION AND MANAGEMENT OF A COMPLEX DISORDER doc

Ngày tải lên : 30/03/2014, 23:20

... Kanbayashi and Toyoshi Hosokawa Preface Understanding the rapid changes in the evaluation and management of peripheral neuropa‐ thies, as well as the complexity of their mechanism, is a mandatory ... rodents and humans [16] Whatever the cause, the translational gap necessitates a bridge between clinicians and basic researchers in order to move from the clinic to the laboratory and back into the ... 169] As postulated by the authors and others, this may explain the perturbed nerve regeneration in diabetes Considering the highly dynamic nerve degeneration /regeneration in the initial stage 37...

172
396
0

Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx

Ngày tải lên : 31/03/2014, 09:20

... reorganized core complex can efficiently shuttle quinones between the RC and the bc1 complex The PMC3/4 isolated complex stimulates our interest, and further studies are in progress to understand the nature ... band very close to the LH1 a band, indicated by the arrow, is apparent in the PufX54* mutant (lane 6) This band was excised from the gel after SDS/PAGE and the protein was identified by using the ... mutant PufXD2)7 neither affects the photosynthetic capability of the bacteria nor the efficiency of exchange of the ubiquinol molecules between the RC and the bc1, as judged from the reduction kinetics...

9
547
0

Báo cáo sinh học: " The association of complex liver disorders with HBV genotypes prevalent in Pakistan" doc

Ngày tải lên : 18/06/2014, 18:20

... from HBV infection) and the rest of the two, one male and other female were in the age range 35 yrs and 45 yrs Thakur et al [39] also concluded that genotype D may predict the occurrence of hepatocellular ... hemogram, liver function tests, coagulation profile, and findings at abdominal ultrasonography, upper gastrointestinal endoscopy and liver biopsy Liver cirrhosis and HCC were diagnosed either on the ... work SB and AAS wrote the manuscript WA, HQ and AA clinically assessed the patients prior to selection and also helped in the clinical data retrieval from the medical records (all were their registered...

7
296
0

báo cáo hóa học:" Function of anterior talofibular and calcaneofibular ligaments during in-vivo motion of the ankle joint complex" docx

Ngày tải lên : 20/06/2014, 01:20

... why their values were larger Burks and Morgan also showed that the ATFL and the CFL have adjacent attachment sites on the anterior edge of the fibula 8–10 mm from the distal tip and that with the ... calcaneus and fibula Once the position of the AJC was reproduced in the modeling software, the length of the ATFL and CFL was measured for Figure dual-orthogonal the in-vivo AJC position using the ... no data has been reported on the elongation of the ATFL and CFL in-vivo The objective of the current study was to measure the change in apparent length of the ATFL and CFL, in-vivo, in uninjured...

6
369
0

Báo cáo hóa học: " The association of complex liver disorders with HBV genotypes prevalent in Pakistan" pdf

Ngày tải lên : 20/06/2014, 01:20

... from HBV infection) and the rest of the two, one male and other female were in the age range 35 yrs and 45 yrs Thakur et al [39] also concluded that genotype D may predict the occurrence of hepatocellular ... hemogram, liver function tests, coagulation profile, and findings at abdominal ultrasonography, upper gastrointestinal endoscopy and liver biopsy Liver cirrhosis and HCC were diagnosed either on the ... work SB and AAS wrote the manuscript WA, HQ and AA clinically assessed the patients prior to selection and also helped in the clinical data retrieval from the medical records (all were their registered...

7
366
0

Báo cáo hóa học: " Non coding extremities of the seven influenza virus type C vRNA segments: effect on transcription and replication by the type C and type A polymerase complexes" ppt

Ngày tải lên : 20/06/2014, 01:20

... analysis of the results and in the writing of the manuscript SW supervised all phases of the project: conception and design of the experiments, analysis of the results and writing of the manuscript ... each other and have the ability to form partially doublestranded structures involved in the transcription and the http://www.virologyj.com/content/5/1/132 replication, in the shape of a panhandle ... polymerase complex and the 3' and 5' ends of the vRNA and its consequences on transcription and replication, we extended our study to reporter vRNA templates harboring the complete 3' and 5' NC...

11
427
0

Báo cáo lâm nghiệp: "Regeneration and game damage in the Krušné hory Mts. assessed on the basis of National Forest Inventory of the Czech Republic" pps

Ngày tải lên : 07/08/2014, 03:22

... birch and other deciduous tree species (rowan accounts for more than 90% of this group) in the open space, below the stand the other deciduous tree species, maple and beech, are behind the spruce ... selected one stand for the measuring of the regeneration and one stand for peeling on 100 710 temporary sample plots are located in sample stands (Verwaltungsvorschrift 2000) The result is then taken ... to the terminal shoot for all species: IFER 19%, NFI 25% But the damage is 19.5% when only the individuals of regeneration in the open space are taken from the database The regeneration in the...

14
438
0