... transient adenovirus infection As a result of both p53 and Rb inactivation, 33 of 34 mice succumbed to ovarian tumors at a median of 227 days However, administration of an adenovirus to achieve the desired ... successfully producing both male and female founders, many females either failed to reproduce or the offspring failed to develop tumors despite high levels of expression of TAg Two of the three female founders ... formation can inhibit reproduction and limit establishment of a reproductive line These models are limited by the lack of a specific promoter for the ovaries, as the MISIIR and keratin promoter are both...
... PLASTICITY AND DAMAGE MODELS – ADDRESSING THE LIMITATIONSOF CLASSICAL MODELS IN SOFTENING AND HARDENING POH LEONG HIEN B.Eng(Hons.), NUS, M.Eng, NUS A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... linear softening von Mises model One broad class of softening models is that of cohesive-frictional materials such as concrete The development and calibration of these models are complicated and ... E van der Giessen, Professor P Steinmann, Professor S Forest, Professor V.S Deshpande, Professor C M Wang and A/Professor W.A.M Brekelmans, for going through the thesis and providing pertinent...
... Instead of dividing datasets during 10-fold cross-validation into training and test subsets with the ratio of 9:1 we randomly split the data into training, validation and test sets with the ratio of ... The Handbook of Computational Linguistics, chapter Segmentation and morphology Blackwell M G Snover and M R Brent 2001 A Bayesian model for morpheme and paradigm identification Proceedings of the ... net increase of 0.0819 of correct boundaries which led to the increased recall Since the deduction of precision is less than the increase of recall, a better over-all performance of P ROMODES...
... on words and their edit status; the latter indicated by one of three possible flags: when the word is not part of a disfluency or E when it is part of the reparandum or I when it is part of the interregnum ... and Johnson (2001) and report the f-score of our disfluency detection system The f-score f is: f = 2c g+e (2) where g is the number of “edited” words in the gold test corpus, e is the number of ... the definitions of Shriberg (1994) regarding speech disfluencies She identifies and defines three distinct parts of a speech disfluency, referred to as the reparandum, the interregnum and the repair...
... as parts of the identification of need and concept definition Parts of the identification of need and concept definition include the development of a basic idea and the first embodiment of the idea; ... architecture and discusses the allocation of functions to components, the tracing and derivation of requirements, the analysis of activation and control structures, and the conduct of various analyses ... are often called invention and are usually not part of the engineering of a system Invention has a heavy technological and scientific focus The last portions of the identification of need and concept...
... ESTIMATION OF NONLINEAR MODELSAND COVARIANCE MATRIX JIANG QIAN (B.Sc and M.Sc Nanjing University) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF STATISTICS AND APPLIED ... when c → and attracts lots of applications in econometrics, finance and biology See, e.g., Chapter of Franses and van Dijk (2000) 1.1.3 Varying Coefficient Model As a hybrid of parametric and nonparametric ... vector of responses, X is an (n × d)-design matrix, β is a d-vector of parameters and ε is an n × vector of IID random errors The penalized least squares estimates are 1.1 Background of the Thesis...
... learning and skills building through observation andof specific techniques and practices Seminar and workshop - These could be in-plant or public offerings Both cost and overall effectiveness of these ... process and is the key issue in education and training development 3.5 Upgrading and expansion of the professional level of workers Vocational training for youth aged 15 and above should be expanded ... congresses of the Communists Party and those of the important meeting of the National Assembly, the Government and the Central Party Committee emphasized the importance of education and training and...
... determination of the basic long-term goals and objectives of an enterprises, and the adoption of courses of action and the allocation of resources necessary for carrying out these goals” (Chandler,1989) ... number of buyers and their relative sizes • The prevalence of backward and forward integration • Ease of entry and exit • The pace of technological change in both production processes and new ... Organisation structure and relationships Division of labor Coordination of divided responsibility Information systems Organisational process and behavior Standards and measurement Motivation and incentive...
... their invaluable suggestions, and comments and to all of my classmates for their various kinds of help and encouragement My warmest thanks are due to my loving parents and my siblings for their absolute ... other teachers of English After collecting the recording data, we, based on the characteristics of vowel and consonant sounds, checked and took notes of their errors, then classified and put them ... manner of articulation: Manner of articulation is how the airstream goes to the barrier and out of the mouth, i.e it describes the type of obstruction caused by the narrowing or closure of articulation...
... overview of the research approach employed; Section describes the case report and study findings; and, finally, Understanding the Limitationsof KMS Section provides a discussion of the findings and offers ... this are offered by Butler (2000) and Broendsted and Elkjaer (2001) who, following Boland et al (1994) and Pentland (1995), recognize the narrow focus of extant perspectives on knowledge and recommend ... Proceedings of IFIP TC8/WG8.3 Conference, Department of Computer and Systems Sciences University of Stockholm and Royal Institute of Technology Checkland P, Holwell S 1998 Information, Systems and Information...
... that the recent financial and economic crisis—the Great Panic and Recession of 2008 and 2009—will both rearrange the economic landscape and affect the focus of economic and financial research going ... includes Ang, Bekaert, and Wei (2008), Chernov and Mueller (2008), H¨rdahl and Tristani o (2008), D’Amico, Kim, and Wei (2008), Haubrich, Pennacchi, and Ritchken (2008), and Adrian and Wu (2008) 20 ... set of 8standard parameters, this benchmark model can be solved and responses given Quarters of the term premium and the other variables of the model to economic shocks can be computed Figures and...
... Roles of proximal ligand in heme proteins: replacement of proximal histidine of human myoglobin with cysteine and tyrosine by sitedirected mutagenesis as models for P-450, chloroperoxidase, and ... analysis of P450 function Studies on the oxidative transformation of 1-methyl-2phenylcyclopropane and its mono-, di-, and trideuteriomethyl congeners by microsomal CYP2B1 and CYP2E1 suggested ... lifetimes of carbon-centred radicals derived from a diverse set of substrates are on the order of about 10)10 s [98] Moreover, the randomness of the apparent intramolecular KIEs for unrearranged and...
... activity of RP mRNA for adjustment of the biosynthesis of ribosomes to the requirements of cell growth and differentiation In addition, a relevant contribution of protein turnover to the regulation of ... sclerosis complex (TSC)1– TSC2, and the mammalian target of rapamycin (mTOR) C1 complex (composed of raptor, mLst8, and mTOR) The role of TSC1–TSC2 in the translation of TOP mRNAs has been recently ... mechanism of DBA in cultured cells showed that alteration of any of the involved RPs can affect the maturation of rRNA [72] Moreover, investigations on the effect of mutations on the synthesis of RPS19...
... the focus of presentations and discussions: l l l l Online andof ine coupling of meteorological and air quality models Implementation of feedback mechanisms, direct and indirect effects of aerosols ... practice, and gives recommendations for on-line and off-line coupling of NWP and ACT models, implementation strategy for different feedback mechanisms, direct and indirect effects of aerosols and advanced ... Systems of Meso-Meteorological and Chemical Transport Models Alexander Baklanov Alexander Mahura Ranjeet S Sokhi l l Integrated Systems of Meso-Meteorological and Chemical Transport Models Editors...
... span? For T RIE and L IST, an active state cor- n Figure 12: Grammar sizes: active state counts responds to a prefix of a rule and is a mix of POS tags and phrasal categories, each of which must ... using the bottoms of chains increases the frequency of tags relative to categories 16 This is also false; tags occur slightly more often at the beginnings of rules and less often at the ends ... number of tags andof categories in Call this pair the signature of For a given signature , let be the number of active states in the grammar which have that signature Now, take a state of signature...
... that of the Western and Midland regions of the United States, while the phonological system of western Canadian English is identical to that of the Pacific Northwest of the United States, and ... rough unit of distance derived from the length of the same ―Office‖ - BE- a government department ("Colonial Office", "Foreign and CommonwealthOffice") the outbuildings and dependencies of a dwelling ... linguists And vocabulary, which is considered a very important branch of English language, is investigated and studied by many of lexicologists However, most of us often care for vocabulary and grammar...
... hates football (Hanh, 2006:90) Lexemes like on and off, good and bad, love and hate are pairs of antonyms They indicate the words of the same part of speech, which have contrasting or opposite ... the age of wisdom, it was the age of foolishness, it was the epoch of belief, it was the epoch of incredulity, it was the season of light, it was the season of darkness, it was the spring of hope, ... chapter II, antonyms of adjectives, antonyms of verbs, antonyms of nouns, and antonyms of adverbs are studied carefully Antonyms of polysemantic nouns In the part, we study the cases of polysemantic...
... - 10%, and on handicraft - 4.4% In 2005, the rate of labor of town made up 49.6% of the total population, but the number of labor having professional technical education is only 34.1%; of which ... 2.81% of natural land area, however, aquaculture production is still potential and its capability can be expanded further based on the potential of exploitation and utilization of tidal peak and ... accounted for 6.2% of GDP in 2004 The marine economic consists of the branches of catching and exploiting organism sources and seafood processing 3.2.1 The catching and exploiting sources of the marine...