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lessons from high throughput studies

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Báo cáo y học: "miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data" pptx

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... miRNAs from high- throughput sequence data In contrast to most current methods, miRTRAP utilizes a system of binary decisions based on known biochemical mechanisms of miRNA biogenesis Numerous studies ... of high- throughput sequencing technology Future small RNA sequencing studies will have far more extensive coverage than what is currently available miRTRAP should be a useful tool for such studies ... could arise from intronic regions of unannotated alternative splicing variants Discussion We have presented a new computational method for the systematic identification of miRs using high- throughput...
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Báo cáo y học: "Estimating enrichment of repetitive elements from high-throughput sequence data" ppt

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... used in the context of other types of high- throughput sequencing experiments, most notably for analysis of copy-number variation of repetitive sequences from comparative genomic sequencing data ... examined marks are known to show high genomewide levels of enrichment, and are therefore not expected to show a high magnitude of depletion To account for variation stemming from small read counts, each ... doi:10.1186/gb-2010-11-6-r69 Cite this article as: Day et al.: Estimating enrichment of repetitive elements from high- throughput sequence data Genome Biology 2010 11: R69 Submit your next manuscript to BioMed...
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Báo cáo khoa học: 15 N-Labelled proteins by cell-free protein synthesis Strategies for high-throughput NMR studies of proteins and protein–ligand complexes doc

Báo cáo khoa học: 15 N-Labelled proteins by cell-free protein synthesis Strategies for high-throughput NMR studies of proteins and protein–ligand complexes doc

Báo cáo khoa học

... purification: a high- throughput approach FEBS Lett 524, 159–162 22 Keppetipola S, Kudlicki W, Nguyen BD, Meng X, Donovan KJ & Shaka AJ (2006) From gene to HSQC in under five hours: high- throughput ... protein synthesis and combinatorial isotope labelling will become routine techniques in high- throughput NMR studies of proteins Acknowledgements GO and KO thank the Australian Research Council (ARC) ... cell-free protein synthesis particularly attractive for high- throughput production of proteins and selective isotope labelling starting from relatively expensive isotope labelled amino acids A...
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Connecting gender and economic competitiveness: lessons from Cambridge''''s high-tech regional economy potx

Connecting gender and economic competitiveness: lessons from Cambridge''''s high-tech regional economy potx

Cao đẳng - Đại học

... have historically dominated high- tech labour forces, and hence the corporate case studies on which many scholars have drawn However, female labourparticipation rates in high- tech firms have significantly ... high- tech regional economies including Oxford, London, and the M4 corridor Moreover, results from the wider research project of which this paper is part show that the gender inequalities we highlight ... European Planning Studies 25 ^ 41 Markusen A, 1999, ``Fuzzy concepts, scanty evidence, policy distance: the case for rigour and policy relevance in critical regional studies' ' Regional Studies 33 869...
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Báo cáo y học: "Lessons from dynamic cadaver and invasive bone pin studies: do we know how the foot really moves during gait" potx

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... joint in some feet, is perhaps one of the most important findings from the recent dynamic cadaver and invasive foot kinematic studies This is important because data demonstrate that the tarsal ... lateral arch of the foot There is an important observation from the slow running data reported by Arndt et al [27] and walking data from Lundgren et al [26], which is even more valuable since ... control foot movements One extrapolation from this observation is that foot orthoses for running need not be stiffer or have greater 'control' features (such as high levels of medial heel wedging)...
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báo cáo khoa học: " Moderate- to low-risk variant alleles of cutaneous malignancies and nevi: lessons from genome-wide association studies" pdf

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... individuals with CM and 36,723 non-CM controls from Iceland; 1,033 CM cases and 2,650 controls from Sweden and 278 CM cases and 1,297 controls from Spain) were tested for melanoma risk effects ... appear to be related to, but distinct from, CM development A meta-analysis of 46 different studies related to nevus formation and melanoma risk showed that a high mole count (101 to 120) increased ... over six times higher between the presence of five atypical moles and no moles at all (RR = 6.52; 95% CI) [33] These studies clearly http://genomemedicine.com/content/1/10/95 highlight that an...
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Báo cáo y học: "Genomics - from Neanderthals to high-throughput sequencing" ppsx

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... shared haplotypes in case-control studies was presented by Ingileif Hallgrímsdóttir (University of Oxford, UK) This involves inferring co-inheritance alleles from a parent using haplotype data ... researchers promise to make this a valuable resource as it grows to cover more of the genome Lessons from comparative genomics The main contribution of comparative genomics has been to identify ... has contributed genomic information from mammoths, cave bears and Neanderthals The small amount of data available so far indicate that Neanderthals diverged from modern humans (Homo sapiens) 400,000...
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On interaction motif inference from biomolecular interactions riding the growth of the high throughput sequential and structural data

On interaction motif inference from biomolecular interactions riding the growth of the high throughput sequential and structural data

Cao đẳng - Đại học

... 2004 From then on, the number increases until it reaches ∼ 150000 known interactions today [101] More interactions are identified in high throughput experiments (59.8%) as opposed to low throughput ... programs in this line would be of high importance for mining more SLiMs from the PPI data We designed another method, SLiMDiet, which collects all possible de-novo SLiMs from the structural data in ... characterized 452 distinct SLiMs from the Protein Data Bank (PDB), of which 155 are validated by either literature validations or over-representation in high throughput PPI data We further observed...
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Lessons from East Asia''''a Recent Experience

Lessons from East Asia''''a Recent Experience

Cao đẳng - Đại học

... more than two percentage points in 1995 from under 6.3 percent to 8.5 percent of GDP, while Thailand’ which had been high throughout the 1990s— increased s— from 5.6 percent of GDP in 1994 to percent ... widened several times from percent in January 1994 up to percent in September 1996 22 requirements from percent of deposit liabilities to percent, which was made effective as from February 1996, ... asset booms and rising exposure to risky sectors; (iii) high leverage; and (iv) currency and maturity mismatches that left some economies highly vulnerable to reversals in capital flows There were,...
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24 LESSONS FROM THE WORLD’S GREATEST CEO

24 LESSONS FROM THE WORLD’S GREATEST CEO

Quản trị kinh doanh

... take anyone from Roosevelt to Churchill to Reagan—inspire people with clear versions of how things can be done better.” 38 Learn good ideas from inside the company Get good ideas from everywhere ... terrified by speed and hates simplicity.” This page intentionally left blank The Welch Way 24 Lessons from the World’s Greatest CEO J E F F R E Y A K R A M E S M C G RAW -H ILL New York Chicago ... trust them to their jobs Involve everyone and welcome great ideas from everywhere: Since business is all about getting the best ideas from everyone, be sure to leave no one out It just might be the...
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Lessons from NAFTA_chap7

Lessons from NAFTA_chap7

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... Spain and Portugal benefited from the creation of additional FDI resulting from strong economic growth in the EU rather than from an investment diversion effect away from non-EU countries EU Eastern ... both from within and outside the FTA, who export back from their host to the FTA, since now it will be cheaper to so from member countries than from nonmember countries While foreign investment into ... which each host deviates from its average behavior, and from the average behavior of the sample as a whole, in a given year Thus, to see if Mexico behaves differently from the rest of the sample...
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5 twitter lessons from the obama and romney campaigns

5 twitter lessons from the obama and romney campaigns

Internet Marketing

... a "sponsored tweet" that turned up high on the list when people clicked on "Big Bird." Build and engage your communit y Find out what people expect and want from your brand As an example, Steele...
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Tài liệu Lessons From the Public Speaking ppt

Tài liệu Lessons From the Public Speaking ppt

Kỹ năng nói tiếng Anh

... Lessons From the Public Speaking Gold Mine Lessons From the Public Speaking Gold Mine “A Revolutionary, Step-By-Step Roadmap ... to carry the talk from there but the point being, if you’re a non-fee paid speaker, you don’t necessarily get the co-operation and the interest from the organizer or possibly from your audience ... www.1publicspeakinggoldmine.com/offer.html Lessons From the Public Speaking Gold Mine play it back with a partner and have the partner critique you – when you read it, put major emphasis on the highlighted word or...
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Global perspectives on governance: lessons from east and west

Global perspectives on governance: lessons from east and west

Quản trị kinh doanh

... perspectives on governance: lessons from east and west | In practice, many multinationals from the east and west have approached finding a balance by mixing employees from the home office with ... than those in the west The most significant impact they have felt came not from risky lending, but from declining demand from consumers in North America and Europe There was no Asian Lehman Brothers ... generally’ he says Global perspectives on governance: lessons from east and west | John Kay has observed competitive advantages derived from structures of implicit contracts with suppliers, employees...
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Sustainability in emerging markets: Lessons from South Africa

Sustainability in emerging markets: Lessons from South Africa

Quản trị kinh doanh

... one of the Jaycees’ ‘Four Outstanding Young South Africans.’ With an MA from Cambridge in England, Chris also holds an MBA from Henley Business School Tanya Barman is CIMA’s ethics manager and ... drivers and to create the related metrics, is an increasing priority The focus from the outside world will shift from observing whether a company reports externally on sustainability information ... project (A4S) with input from the main accounting bodies and other key stakeholders (see box 3, p18) At the same time emerging markets were rapidly changing their profile, from being centres for...
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Tài liệu Women’s Health and Postsocialist Healthcare Reforms: Lessons from Poland and Eastern Europe ppt

Tài liệu Women’s Health and Postsocialist Healthcare Reforms: Lessons from Poland and Eastern Europe ppt

Sức khỏe phụ nữ

... services, gynecological care is not always included Yet, Poland has one of the highest rates of cervical cancer and the highest mortality rate due to this illness in the EU, mainly because less than ... abstinence, or no method at all (Mishtal 2010) The state also privatized prenatal tests by removing them from the “health benefits basket,” thus patients who are well qualified for the service by virtue ... argued in an open letter to the Minister of Health, to no avail, that this excludes many women from otherwise available advances in maternity healthcare and constitutes a patient’s rights and...
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Tài liệu FIRMS AND THEIR DISTRESSED BANKS: LESSONS FROM THE NORWEGIAN BANKING CRISIS (1988-1991) docx

Tài liệu FIRMS AND THEIR DISTRESSED BANKS: LESSONS FROM THE NORWEGIAN BANKING CRISIS (1988-1991) docx

Ngân hàng - Tín dụng

... method, and various other empirical robustness tests Our findings differ markedly from studies that use similar data from Japan or other East Asian countries For instance, using data sampled during ... Japanese banks are forbidden from directly owning more than 5% of a non-financial company 26 See From Bad to Worse,” The Economist, 9/23/00 27 Norwegian law forbids a bank from directly owning a stake ... supplying Norwegian data, and Andy Naranjo for providing us with data from Datastream Ongena thanks the Center for Financial Studies in Frankfurt for their hospitality and the Fund for Economic...
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Tài liệu The German Banking System: Lessons from the Financial Crisis pptx

Tài liệu The German Banking System: Lessons from the Financial Crisis pptx

Ngân hàng - Tín dụng

... William Tompson and Laura Vartia 757 Advancing structural reforms in OECD countries: Lessons from twenty case studies (April 2010) by William Tompson and Thai-Thanh Dang 756 Labour markets and ... available on OLIS in its original format ECO/WKP(2010)44 SUMMARY/RESUME The German banking system: lessons from the financial crisis The German banking system came under pressure during the financial ... the activities of the Landesbanken which benefitted from government guarantees without a proper business model; ii) weak capitalization and high fragmentation of the whole banking system, possibly...
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