lectins peptides and associated biological activities
Characterization of murine soluble CD137 and its biological activities
... receptor -associated factor (TRAF1) and TRAF2, leading to activation of nuclear factor κB (NF-κB) and the extracellular signal regulated kinase (ERK), c-Jun N-terminal kinase (JNK) and p38 mitogen -associated ... IL-1, CD40 ligand, LPS and double stranded RNA (Futagawa et al., 2002; Kim et al., 2002; Laderach et al., 2003; Lee et al., 2003) Besides APC, CD137L is also present on murine and human T cell ... of TRAF1 and TRAF2, CD137 activates NF-κB, ERK, JNK and p38 MAPK signaling cascades CD137 promotes T cell survival through upregulation of the anti-apoptotic genes bcl-XL and bfl-1 and the dwonregulation...
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Báo cáo khoa học: Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases pot
... cytomegalovirus replication [15] and HIV-1 RT -associated RDDP and integrase activities [18,19] Recently, we reported that some derivatives of the AQ emodine inhibit HIV-1 RT -associated RNase H activity ... synthesis of the minus () strand DNA that uses (+)-strand RNA as template [2,3] HIV-1 RNase H, similar to all the RNase Hs and together with transposases, retroviral integrases and RuvC resolvase, belongs ... family and catalyzes the phosphoryl transfer through nucleophilic substitution reactions on phosphate esters [4] Even though both RT -associated activities are essential for virus replication and, ...
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báo cáo hóa học: " Leader (L) and L* proteins of Theiler''''s murine encephalomyelitis virus (TMEV) and their regulation of the virus'''' biological activities" docx
... and L* that are located in the N end of the polyprotein (Fig 2) also play a role in TMEV biological activities [2,3,12] The present review focuses on the roles of L and L* in regulating the biological ... biological activities of TMEV TMEV: properties and biological activities The TMEV virion is an icosahedron approximately 28 nm in diameter with no lipid-bilayer envelope A singlestranded RNA is ... biological activities, i.e., virus persistence and demyelination Further studies clarifying the roles of L and L* will elucidate the pathomechanism(s) of TMEV-induced demyelinating disease, and...
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Study on chemical constituents and biological activities of some plants of boerhaavia genus (nyctaginaceae)
... C23H24O12 + Na, 515.1165 H and 13C and spectra (CD3OD) (Appendix 22 and 23): see Table 3.1 and Table 3.2 COSY, HSQC and HMBC spectra (CD3OD) (Appendix 24, 25, and 26) Discussion of chemical ... Boerhaavia diffusa and Boerhaavia erecta for chemical investigation The aim of this research is to isolate and structurally elucidate the compounds and to test biological activities of the compounds ... for C18H14O7 + Na, 365.0637 H and 13C-NMR spectra (Acetone–d6) (Appendix 28 and 29): see Table 3.3 and Table 3.4 HSQC and HMBC spectra (Acetone–d6) (Appendix 30 and 31) Discussion of chemical...
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Phosphinegold(I) thiolates synthesis and biological activities
... Thiolates: Synthesis and Biological Activities XV Chapter Introduction Phosphinegold(I) Thiolates: Synthesis and Biological Activities Chapter Introduction 1.1 The physical and chemical properties ... Phosphinegold(I) Thiolates: Synthesis and Biological Activities VII List of Figures Figure 89 The correlation of descriptors and the biological activity of Thiocarbamate ligands on HT29 cancer cell at ... Synthesis and Biological Activities IV List of Figures Figure 17 Labeling scheme for the thiolcarbamate ligands 52 Figure 18 Labeling scheme for the thiolates and phosphine ligands 55...
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Study on chemical constituents and biological activities of the lichen parmotrema Praesorediosum(NYL ) hale(parmeliaceaf)
... on the lichen genus Parmotrema 1.3 BIOLOGICAL ACTIVITIES 14 1.3.1 The biological significance of lichen metabolites 14 1.3.2 The biological significance of the lichen Parmotrema ... of PRAES-E11, PRAES-T4 and PRAES-E2 52 Figure 3.9 HMBC and NOESY correlations of PRAES-C22 54 Figure 3.10 HMBC and NOESY correlations of PRAES-C23 56 Figure 3.11 HMBC and NOESY correlations of ... 3.20 HMBC and ROESY correlations of PRAES-C16 80 Figure 3.21 HMBC and ROESY correlations of PRAES-C20 85 Figure 3.22 1H NMR data of PRAES-C18 and diphenyl ether 87 Figure 3.23 HMBC and ROESY...
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STUDY ON CHEMICAL COMPOSITIONS AND BIOLOGICAL ACTIVITIES OF annona glabra l
... compositions and biological activities of Annona glabra L So, the thesis’s title was proposed to be "Study on chemical compositions and biological activities of Annona glabra L." Subject and contents ... acetogenins, entkauranes, peptides, and alkaloids In addition, a lot of isolated compounds exhibited potent anticancer, anti HIV-reserve transcriptase, and anti-malarial activities This research ... 5.53) and C17 (δC 175.3); H-1″ (δC 5.43) and C-19 (δC 178.4) confirmed the positions of two glucopyranosyl moieties at C-17 and C-19 The observation of NOESY correlation between H-18 (δH 1.24) and...
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Community of soft coral alcyonium digitatum associated bacteria and their antimicrobial activities
... both chemical and biological analyses in order to identify the biological activity and identify the antimicrobial substances 14 Material and Methods MATERIAL AND METHODS Sampling and cultivation ... compared to bacteria associated with two soft corals Rhytisma fulvum and Xenia sp (Shnit-Orland and Kushmaro, 2009) 10 Introduction Biotechnological potential of soft corals and coral associated bacteria ... and Vibrio vulnificus (ATCC29307) (Nithyanand and Pandian, 2009) Roseobacter sp isolated from mucus of the Mediterranean coral Oculina patagonica displayed a broad spectrum of antimicrobial activities...
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Effect of secondary structure on biological activities of antimicrobial peptides
... gram-negative and gram-positive bacteria and, more importantly, negligible hemolytic activity Materials and methods Peptide synthesis and purification Synthesis of the peptides were carried out by standard ... Structure has effect on biological activities of antimicrobial peptides, we designed an antimicrobial peptide 45 HPRP-A1, HPRP-A2 (W12K/K15W), a β-sheet peptide and a random coiled peptide without ... β-sheet and α-helical peptides as a determinant for locating the peptides at the interface region of prokaryotic membranes and decreasing transmembrane penetration into eukaryotic membranes and (iii)...
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An investigation into english learning styles of the 11th grade students and some suggested activities = nghiên cứu phong cách học tiếng anh của học sinh lớp 11 và một vài hoạt động gợi ý
... Background 1.1 First and Second Language Learning: 3 1.1.1 First and Second Language: 1.1.2 Learning and Acquisition: 1.1.3 First and Second Language Learning: ... students and Some Suggested Activities Aims of the Study The study aims at - Investigating into learning styles and its benefits in second language learning - Providing teachers, students with activities ... presented with some comments and anlysis The author describes the aims, informant and settings, survey questionnaires, results and findings to make the clear understanding about students' learning...
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An investigation into learning and teaching english vocabulary at cua lo hihg school and some suggested activities to help students learn better
... methods are not various and interesting enough to motivate students attitude English is a foreign language and needs the creation and activity of both teachers and students And here the author wants ... like substandard, ungrateful, and untranslatable New combinations using prefixes are not unusual, and the reader or hearer would be expected to gather their meaning from an understanding of their ... sounds, especially where such distinction change meaning (live /i/ and leave /i:/ for example), and we will also help them to understand and use certain sound rules - for example the different pronunciations...
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Tài liệu Báo cáo khoa học: An allosteric DNAzyme with dual RNA-cleaving and DNA-cleaving activities doc
... that DNA-cleaving and RNA-cleaving activities could not coexist within a DNA motif, and the double activities competed with each other Because DRc DNAzyme has comparatively high activities, we focused ... (30 mM Hepes) and 23 °C with 0.3 M NaCl and 10 lM L-ascorbate In (B), the reactions were conducted under different pH conditions with 0.3 M NaCl, 10 lM L-ascorbate, and 10 lM CuCl2, and were incubated ... 25.8 and 53.7 °C When evaluating the optimal design for a DNAzyme with respect to DNA-cleaving and RNA-cleaving activities, we found that a number of nucleotides within the catalytic core and...
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Tài liệu Báo cáo khoa học: Delineation of exoenzyme S residues that mediate the interaction with 14-3-3 and its biological activity ppt
... GST-ExoS(L428A) and GST-ExoS(LD426–427AA) (Table 1) All GST-ExoS derivatives were expressed and purified, and were then employed in protein pulldown experiments (Fig 1) HeLa cells were harvested and the ... lanes 1–3 and 7–9) In contrast, diluted GST-ExoS(L426A) and GST-ExoS(L428A) precipitated fewer 14-3-3 proteins (Fig 2, lanes 4–6 and 10–12) Thus, the two leucine amino acids at positions 426 and 428 ... e.g., cells rounded up and became semidetached from the Petri dish Both loose and semidetached cytotoxic cells were washed free from bacteria and transferred to a new Petri dish and incubated overnight...
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Tài liệu Photoreceptor Sensory Cilium and Associated Disorders pptx
... diseases, and photoreceptor degeneration and blindness [6-7, 16-18] Photoreceptor sensory cilium and its components In photoreceptors (rods and cones), cilia are highly specialized and modified ... links and to further delineate the roles of TZ proteins in regulating protein trafficking and photoreceptor OS development and function Author details Linjing Li, Ozge Yildiz, Manisha Anand and ... A and Leroux, M R Intraflagellar transport and the generation of dynamic, structurally and functionally diverse cilia Trends Cell Biol 2009; 19(7) 306-316 Photoreceptor Sensory Cilium and Associated...
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Tài liệu Photoreceptor Sensory Cilium and Associated Disorders docx
... diseases, and photoreceptor degeneration and blindness [6-7, 16-18] Photoreceptor sensory cilium and its components In photoreceptors (rods and cones), cilia are highly specialized and modified ... links and to further delineate the roles of TZ proteins in regulating protein trafficking and photoreceptor OS development and function Author details Linjing Li, Ozge Yildiz, Manisha Anand and ... A and Leroux, M R Intraflagellar transport and the generation of dynamic, structurally and functionally diverse cilia Trends Cell Biol 2009; 19(7) 306-316 Photoreceptor Sensory Cilium and Associated...
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Tài liệu Báo cáo Y học: Characterization of an omega-class glutathione S-transferase from Schistosoma mansoni with glutaredoxin-like dehydroascorbate reductase and thiol transferase activities pptx
... hydroquinone and p-chloranil In contrast, SmGSTO showed DHA and HEDS-measured TTase activities Kinetic parameters were obtained for DHA and TTase activities SmGSTO showed a Km ¼ 0.23 mM for HEDS and a ... known GSTs classes and S mansoni GSTs, allowed us to place the new parasite product among the newly identified GSTO class, and the previously characterized Sm28GST and Sm26GST as mu- and sigma-class, ... towards the classical GST substrate 1-chloro-2,4dinitrobenzene (CDNB); and (c) showed significant GSHdependent TTase and DHA activities The data presented here provide the first evidence for a potential...
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Nutritional Status and Associated Factors in Institutionalized Elderly docx
... ability to perform activities of daily living and greater dependence on care, including meals and purchase of food [19] The results of the Health, Welfare and Aging in Latin America and the Caribbean ... prevalence of overweight and high risk of diseases associated with obesity and cardiovascular disease according to BMI, WC and WHR BMI is highly correlated with body weight and has proximity to the ... vitamins and minerals, was not associated with nutritional status, or with socioeconomic data On the other hand, the mobility of the elderly, their financial contribution to the ILPI and frequency...
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Báo cáo khoa học: Role of different moieties from the lipooligosaccharide molecule in biological activities of the Moraxella catarrhalis outer membrane pot
... membrane biological activities have become apparent over years of extensive research and there is indication today that the outer membrane of gramnegative bacteria has some other biological activities, ... killing, and reduced adherence to human epithelial cells in vitro and in vivo, while showing hypersensitivity to hydrophobic compounds, indicating that LOS contributes to most biological activities ... dissected into three OS chains and a linker composed of a central Glc and two 3-deoxy-d-manno-2-octulosonic acids (Kdo) How the three moieties play their roles in biological activities of the outer...
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