lab of pierluigi gambetti md

Báo cáo khoa học: Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3) docx

... threshold of accurate detection and reproducibility of our current assay; and would represent < 1% of the activity of the wild-type enzyme We then determined, by photoaffinity labeling, whether any of ... and visibly only in the presence of drugs (± Vi) These results are reminiscent of previous studies of double-mutants of the IC in human and Fig Photolabeling of Abcb1a NBD mutants by vanadate ... sequence of the entire 402 bp BglII–XmaI fragment was determined Purification of Abcb1a For expression and purification of the six single and three double mutants, pHIL–mdr3–His6 or pHIL–mdr3.5–His6...

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Acetic Acid Bacteria - screening of LAB strains

Danh mục: Sinh học

... classification of LAB as Gram-positive, catalase negative and oxidase negative [21] Classification of the isolates led to identification of species The frequency of occurrence of lactic acid ... highest number of LAB isolated from fermented plant materials The involvement of various types of LAB in fermented vegetables and plant materials had earlier been reported [23-25] Thus LAB were present ... be due to the fact that majority of the substrate used in the preparation of the fermented foods are of plant origin The identification of different types of LAB species in the present study...

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Lab 1: Game of Life

Danh mục: Công nghệ thông tin

... output to the Lab Assistant Check off: Part B: The World in a File In the first part of this lab, the initial state of the world was hard-coded into lifegame.c and the final state of the world was ... for compiling this code: athena%1 gcc -g -O0 -Wall lab1 a.c lifegame.c -o lab1 a.o athena% Start by examining the contents of lifegame.h and lab1 a.c You need to fill in a few lines in main() and ... located at (i,j) in the world (c) Fill in the contents of lab1 b.c using the code from Part A (lab1 a.c) and modifying to call these functions The name of the file to load will be specified in the first...

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Lab 6.2.9 Firmware Upgrade of a Catalyst 2900 Series Switch

Danh mục: Quản trị mạng

... are completed, logoff, by typing exit, and turn all the devices off Then remove and store the cables and adapter 3-4 CCNA 3: Switching Basics and Intermediate Routing v 3.0 - Lab 6.2.9 Copyright ... b If, as shown there is no software image defined in the boot path enter dir flash: or show flash to display the contents as follows: ALSwitch#dir flash: Directory of flash:/ -rwx 1674921 Mar ... Directory of flash:/ -rwx 1674921 Mar 01 1993 01:28:10 c2950-c3h2s-mz.120-5.3.WC.1.old -rwx 269 Jan 01 1970 00:00:57 env_vars 2-4 CCNA 3: Switching Basics and Intermediate Routing v 3.0 - Lab 6.2.9...

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Tài liệu Lab 1.2.3 Review of Basic Router Configuration with RIP doc

Danh mục: Quản trị mạng

... steps are completed, logoff by typing exit, and turn the router off Then remove and store the cables and adapter - 10 CCNA 3: Switching Basics and Intermediate Routing v 3.0 - Lab 1.2.3 Copyright ... is no way to effectively list all of the combinations of configurations for each router class What is provided are the identifiers for the possible combinations of interfaces in the device This ... started! Press Enter Now the router is ready for the assigned lab to be performed - 10 CCNA 3: Switching Basics and Intermediate Routing v 3.0 - Lab 1.2.3 Copyright  2003, Cisco Systems, Inc Router...

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Tài liệu Lab 3.1.1 Safe Handling and Use of a Multimeter docx

Danh mục: Quản trị mạng

... for this? _ Step Put the tip of the red, positive lead on the positive side of a battery Put the tip of the black, negative, lead on the other end of a battery a Is any number showing ... important function of a multimeter _ If a voltage is negative when measuring a battery, what is wrong? 2-2 CCNA 1: Networking Basics v 3.0 - Lab 3.1.1 Copyright ... Is any number showing up on the multimeter? _If not, make sure to switch to the correct type of measurement For example Vol, voltage, or V If the voltage is negative, reverse the leads Reflection:...

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Tài liệu Lab 3.1.1 Safe Handling and Use of a Multimeter doc

Danh mục: Quản trị mạng

... for this? _ Step Put the tip of the red, positive lead on the positive side of a battery Put the tip of the black, negative, lead on the other end of a battery a Is any number showing ... important function of a multimeter _ If a voltage is negative when measuring a battery, what is wrong? 2-2 CCNA 1: Networking Basics v 3.0 - Lab 3.1.1 Copyright ... Is any number showing up on the multimeter? _If not, make sure to switch to the correct type of measurement For example Vol, voltage, or V If the voltage is negative, reverse the leads Reflection:...

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Tài liệu Lab 9.1.2 Gateway of Last Resort ppt

Danh mục: Quản trị mạng

... Upon completion of the previous steps, log off by typing exit and turn the router off 3-5 CCNA 2: Routers and Routing Basics v 3.0 - Lab 9.1.2 Copyright  2003, Cisco Systems, ... interfaces This will identify the type of router as well as how many interfaces the router has There is no way to effectively list all of the combinations of configurations for each router class ... possible combinations of interfaces in the device This interface chart does not include any other type of interface even though a specific router may contain one An example of this might be an...

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Tài liệu Lab 9.1.2 Gateway of Last Resort (Default Gateway) pdf

Danh mục: Quản trị mạng

... Upon completion of the previous steps, log,off by typing exit and turn the router off 3-5 CCNA 2: Routers and Routing Basics v 3.0 - Lab 9.1.2 Copyright  2003, Cisco Systems, ... interfaces This will identify the type of router as well as how many interfaces the router has There is no way to effectively list all of the combinations of configurations for each router class ... possible combinations of interfaces in the device This interface chart does not include any other type of interface even though a specific router may contain one An example of this might be an...

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Tài liệu Lab 3.2.5 Configuring Message-of-the-Day (MOTD) pptx

Danh mục: Quản trị mạng

... privileged EXEC command mode Upon completion of the previous steps, logoff by typing exit Turn the router off 2-4 CCNA 2: Routers and Routing Basics v 3.0 - Lab 3.2.5 Copyright  2003, Cisco Systems, ... interfaces This will identify the type of router as well as how many interfaces the router has There is no way to effectively list all of the combinations of configurations for each router class ... possible combinations of interfaces in the device This interface chart does not include any other type of interface even though a specific router may contain one An example of this might be an...

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Tài liệu Lab 3.2.5 Configuring Message of the Day pdf

Danh mục: Quản trị mạng

... privileged exec command mode Upon completion of the previous steps, logoff by typing exit Turn the router off 2-4 CCNA 2: Routers and Routing Basics v 3.0 - Lab 3.2.5 Copyright  2003, Cisco Systems, ... interfaces This will identify the type of router as well as how many interfaces the router has There is no way to effectively list all of the combinations of configurations for each router class ... possible combinations of interfaces in the device This interface chart does not include any other type of interface even though a specific router may contain one An example of this might be an...

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Tài liệu Lab 6.2.9 Firmware Upgrade of a Catalyst 2900 Series Switch doc

Danh mục: Quản trị mạng

... are completed, logoff by typing exit, and turn all the devices off Then remove and store the cables and adapter 3-5 CCNA 3: Switching Basics and Intermediate Routing v 3.0 - Lab 6.2.9 Copyright ... Inc Erasing and Reloading the Switch For the majority of the labs in CCNA and CCNA it is necessary to start with an unconfigured switch Use of a switch with an existing configuration may produce ... ALSwitch#dir flash: Directory of flash:/ -rwx 1674921 Mar 01 1993 01:28:10 c2950-c3h2s-mz.120-5.3.WC.1.old 2-5 CCNA 3: Switching Basics and Intermediate Routing v 3.0 - Lab 6.2.9 Copyright  2003,...

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Tài liệu Freshwater sponges as indicators of water pollution: an investigative undergraduate lab pdf

Danh mục: Điện - Điện tử

... funding the development of this laboratory through a Laboratory Teaching Initiative Grant C Stabile conducted many of the preliminary experiments Table Selected compounds of interested, their sources, ... several other reasons why sponges are a model laboratory organism to explore the biological consequences of environmental pollution For the purposes of ease of set-up, freshwater sponges represent ... examine 1) the effects of chemicals on sponge growth, and 2) the effects of pollutant concentration on sponge growth The choice of chemicals will be at the discretion of the instructor and research...

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Tài liệu Báo cáo khoa học: Switching of the homooligomeric ATP-binding cassette transport complex MDL1 from post-translational mitochondrial import to endoplasmic reticulum insertion pptx

Danh mục: Báo cáo khoa học

... 1% of the total mitochondrial protein This correlates with an over-expression compared to native MDL1 of up to 100-fold To determine the localization of MDL1 in S cerevisiae, mitochondria of Dmdl1 ... kinetics with a Km ATP of 120 ± lM and 200 ± lM and a kcat of 74 ± ATPÆmin)1 and 77 ± ATPÆmin)1 (per MDL1 monomer), respectively Inhibition of ATPase activity of MDL1 (C) and MDL1(60-695) (D) by ... downstream of the primer [28] Cassette I includes the N-terminal part of the TMD (M1 to A220), cassette II the C-terminal part of the TMD (S221 to K422), and cassette III the NBD of MDL1 (D423...

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Tài liệu Báo cáo khoa học: Treatment of neutral glycosphingolipid lysosomal storage diseases via inhibition of the ABC drug transporter, MDR1 Cyclosporin A can lower serum and liver globotriaosyl ceramide levels in the Fabry mouse model doc

Danh mục: Báo cáo khoa học

... function of MDR1, the GSLs of some other tissues are complicated by the redundancy in this function (studies in progress) and the tissue differences in MDR1 expression Thus, an effect of MDR1 inhibition ... indicate the feasibility of using inhibition of MDR1 as an approach to the treatment of Fabry disease Although the efﬁcacy may not, as yet, be as dramatic as ERT, inhibition of MDR1 may prove most ... and have shown that the inhibition of MDR1 is a viable potential approach to the reduction of Gb3 in both the serum and certain tissues of this model Results MDR1 inhibition in LSD cell lines...

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Tài liệu C++ Lab 6 Review of Variables, Formatting & Loops docx

Danh mục: Kỹ thuật lập trình

... the program from Lab (the grades program) to add a while loop First step is to decide which of the variables can be selected as loop control variable If no variables are available to select, ... initialize the LCV; (4) setup the while loop condition; (5) write the body of the loop; and (6) change the value of LCV within the body of the loop Program 6-4 /****************************************** ... provides several input and output format manipulators Here is a summary of the most commonly used ones An explanation of numeric formatting also is given This section is obtained from the Visual...

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Complications of Pediatric Sinusitis - Naana Afua Jumah, HMS III Gillian Lieberman, MD doc

Danh mục: Mỹ thuật

... Lieberman, MD Patient BE: Cerebral Edema on MRI Axial MR T1 Pre-contrast Midline shift Compression of the anterior horn of the lateral ventricle Compression of the left posterior horn of the lateral ... HMS III Gillian Lieberman, MD Summary of Patient BE • 11 year old girl with symptoms of sinusitis suspected of having complications • Coronal CT showed opacification of the paranasal sinuses • ... American College of Radiology, 2006 and Boyle, 2006 Naana Afua Jumah, HMS III Gillian Lieberman, MD Abnormal Sinuses in Children Incidence of abnormal sinus CT in children with no history of sinusitis...

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Báo cáo khoa học: "Eﬃcient Optimization of an MDL-Inspired Objective Function for Unsupervised Part-of-Speech Tagging" docx

Danh mục: Báo cáo khoa học

... minimize the size of the model simultaneously We define the size of a model as the number of non-zero probabilities in its parameter vector Let θ1 , , θn be the components of θ We would like ... control over the sparsity of the tag-bigram and channel probability distributions by using a different α for each: We can think of the approximate model size as a kind of prior: log P(θ) = α · ... L0 norm of θ, simply counts the number of non-zero parameters in θ The hyperparameter α controls the tradeoff between likelihood maximization and model minimization Note the similarity of this...

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C++ Lab 15 Review of Arrays, Array of Objects and Vector Dr. John Abraham, Professor doc

Danh mục: Kỹ thuật lập trình

... sum of' x bar means 'the mean' Program 15-2 /************************************************* Read scores from a file into an array Keep track of number of scores entered Find difference of ... store the data, the second one to find the difference of each score from the mean and the third one to find store the square of deviation of each score The mean is calculated by adding all valid ... card shuffling program Here we have an array with names of a deck of card We not actually shuffle this array, instead we create an array of integers (shuffled[]) and place random numbers from...

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The Future of Medical Education in Canada (FMEC): A Collective Vision for MD Education ppt

Danh mục: Sức khỏe giới tính

... part of interand intra-professional teams Rationale The nature of medical practice is not static Changes in the scope of practice of many health care providers and the emergence of new professions ... Angela Towle Associate Dean MD Undergraduate Education Faculty of Medicine University of British Columbia W Todd Watkins Director Office of Professional Affairs Professional Affairs Directorate ... Faculties of Medicine of Canada (AFMC) Project Staff Catherine Moffatt Project Manager The Association of Faculties of Medicine of Canada (AFMC) Claire de Lucovich Project Assistant The Association of...

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