l strandberg l lenardo mj 2008 the selectivity of autophagy and its role in cell death and survival autophagy 4 567 573
Expression dynamics of the hepatic mitochondrial proteome of the sod2+ mouse in response to troglitazone administration
... heteroplasmy During cell division of heteroplasmic cells, cytokinesis will lead to the distribution of mutant mtDNA to other daughter cells, and as a consequence may lead to an expansion of homoplasmic ... overwhelm any inherent biological defence, eventually triggering overt liver injury The notion of abnormal mitochondria playing the role of a susceptibility factor in DILI is relatively new, and ... absence of albumin, where albumin sequesters 95 to 99% of plasma troglitazone, thereby reducing the bioavailability (pharmacologically and toxicologically) 18 of the drug (Chojkier, 2005, Loi et al.,...
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Tài liệu Báo cáo khoa học: Altered inactivation pathway of factor Va by activated protein C in the presence of heparin doc
... reaction intermediate, FVaint This facilitated the determination of loss of FVa cofactor activity during the initial stage of inactivation and minimized the in uence of the k306 Ó FEBS 20 04 Heparin and ... heparin inhibits cleavage at Arg506 and stimulates initial cleavage at Arg306, inactivation of Fig Kinetic analysis of the inactivation of FVa by APC in the presence and absence of heparin Initial ... clotting factors Blood 78, 1637–1651 Esmon, C.T (1989) The roles of protein C and thrombomodulin in the regulation of blood coagulattion J Biol Chem 2 64, 47 43– 47 46 Kalafatis, M., Rand, M., D., Mann,...
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Báo cáo khoa học: The effect of replacing the axial methionine ligand with a lysine residue in cytochrome c-550 from Paracoccus versutus assessed by X-ray crystallography and unfolding ppt
... seems likely that the mechanism of release of the axial ligand under alkaline conditions and in the presence of GdmHCl is different Under alkaline conditions release of the axial ligand is postulated ... as the open form, albeit with the axial ligand still intact, with the main- and side-chain atoms of K99 flipped up and away from the heme resulting in an increased solvent exposure of the heme The ... the local unfolding of this region is not under sole control of the axial ligand If so then this suggests the region around the K100 ligand is less stable than in the wt protein This is also inferred...
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Báo cáo Y học: Cloning and expression of sterol D14-reductase from bovine liver potx
... cells over-expressing D 14- SR; no label was observed in control cells These results are consistent with the known subcellular localization of the enzymes involved in cholesterol biosynthesis and ... Cellular localization The cellular localization of myc-tagD 14- SR was examined in transiently transfected COS-7 cells Double immuno¯uorescence analysis of cells showed a similar labelling pattern with ... C27D8, 14 sterol C27D8 sterol was undetectable at the beginning of incubation both in COS-7 cells and bovine liver microsomes Endogenous D 14- SR activity of microsomes obtained from control COS-7 cells,...
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Báo cáo khoa học: Selective detection of superoxide anion radicals generated from macrophages by using a novel fluorescent probe pdf
... changes in O2–Æ concentration within living cells Overall results establish the potential value of the probe for facilitating investigations of the generation, metabolism, and mechanisms of superoxide-mediated ... Perkin–Elmer, Norwalk, CT) All pH measurements were made using a pH-3c digital A solution of 40 .0 mL of dimethylformamide in 40 .0 mL of methylene chloride was chilled in an ice bath A solution of ... radicals In order to further investigate the feasibility of the proposed method in biological systems, determination of O2–Æ in cell extracts was performed The fluorescence intensity of cell extracts...
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Báo cáo khoa học: Identification of a copper-repressible C-type heme protein of Methylococcus capsulatus (Bath) A member of a novel group of the bacterial di-heme cytochrome c peroxidase family of proteins docx
... Biotin is too large to penetrate the outer membrane and will only label polypeptides that have a lysine-containing sequence accessible at the cell surface The biotinylated cells Heme protein identification ... sample applied); lane 2, 20 mM Tris ⁄ HCl wash (20 lL sample applied); lane 3, 0.5 M NaCl extract (20 lL sample applied); lane 4, whole cells treated with 0.5 M NaCl (10 lL sample applied); lane ... PAGE displayed a complex crude cell- extract protein pattern in the untreated cells and in cells treated with 0.5 and m NaCl (Fig 5A, lanes 1, and 6) Importantly, the large 60 kDa subunit of the MeDH...
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Báo cáo khoa học: "PCR-based detection of genes encoding virulence determinants in Staphylococcus aureus from bovine subclinical mastitis cases" doc
... swoc 43 1 morf selpmas )%67.09( 105 ,smraf no swoc 041 morf detcelloc selpmas klim 255 fo tuO selpmas klim evitisop TMC morf detpmetta saw succocolyhpatS fo noitalosI stluseR elba T noitanimulli ... laccocolyhpatS eht fo noitacifilpma rof sremirP noiger gnidnib-GgI :11-9 enaL ;noiger -X :8-6 enaL :5 enaL ;A :4 enaL ; :3-1 enaL ;)aidnI ,ieneG erolagnaB( 31 DBM rekram thgiew ralucelom AND :M enaL ... muidos dna lonaporposi htiw detatipicerp saw AND )1 : 42 ( lohocla lymaosi :mroforolhc dna )1 : 1( mroforolhc :lonehp htiw noitcartxe yb deifirup saw AND Co56 ta nim 03 rof detabucni dna )lCaN M 7.0...
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Tài liệu Int’l High Performance Network Infrastructure of Korea doc
... Between EU and Asia After the Cold War, the int l society became tri-polar with US, Europe and Asia >> In 1996, resulted in the establishment of the Asia-Europe Meeting (ASEM) Political Idealism ... Singapore, Indonesia, Philippine, Thailand, ASEM ASEAN Int l ICT, IR, 27 Europe-Asia Link to SEA Korea France TEIN II Link (34Mbps) Malaysia Int l ICT, IR, 28 Considering Points ICT hub in NEA ... China Greece, Netherlands, Denmark, Germany, Luxemburg, Belgium, Sweden, Spain, Ireland, UK, Austria, Italy, Portugal, France, Finland, EC Laos, Cambodia, Myanmar, Malaysia, Brunei, Vietnam, Singapore,...
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Báo cáo khoa học: Injection of poly(b-L-malate) into the plasmodium of Physarum polycephalum shortens the cell cycle and increases the growth rate pot
... tolerate artificially increased levels of PMLA The data in Table allow calculation and comparison of the PMLA contents of nuclei in a variety of strains These nuclear contents vary relatively little, ... comparable levels in the nuclei We found that increased cytoplasmic and nuclear levels of PMLA induced a strain specific enhancement of cell growth and an equal (between strains) shortening of the cell ... high and low producers of PMLA (Table 1) In order to study changes in the levels of PMLA in cytoplasm and nuclei, we injected 40 0 lg of the polymer into M3CVII and LU887 plasmodia (weights of 150...
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Child Health And The Quality Of Medical Care by Sarah L. Barber University of California, Berkeley ppt
... cellular level (Pelletier, 19 94) Qj is the quality of prenatal and child 10 medical care available in community j We assume that technical quality changes slowly and the values of quality and other ... including maternal health status and the timing of the insult itself (Hall and Peckham, 1997) Persistent untreated illness early and throughout the pregnancy can result in a reduction of placental ... growth in low-income settings is largely the result of factors amenable to intervention Sound child health policies promote investments in improving the content and quality of prenatal and child...
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Báo cáo khoa học: Novel L-amino acid oxidase with antibacterial activity against methicillin-resistant Staphylococcus aureus isolated from epidermal mucus of the flounder Platichthys stellatus pptx
... surrounding the vacuolated mucus-secreting cells of the gill (Fig 7B), principally within the epithelium of the primary lamellae and secondary lamellae The mucus-secreting cells stained positively ... BM4 147 (VanA+, clinical isolate), E faecalis V583 (VanB+, clinical isolate) and Entero- A flounder LAAO-like antibacterial protein coccus gallinarum BM41 74 (VanC1+, clinical isolate); and the gram-negative ... showed that psLAAO-positive cells were present in the gill These results suggest that psLAAO has tissuespecific expression and is localized in gill Interestingly, using cloning analysis, we identified...
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The Project Gutenberg EBook of Creating Capital, by Frederick L. Lipman pot
... to the practice of certain virtues Thus we contrast profits and patriotism; enriching one's self and philanthropy; getting all the law allows and justice; taking advantage of the other fellow and ... could well be replied that consideration of patriotism, philanthropy, love of family, etc., must in themselves impel one to earn and to save "The love of money is the root of all evil" implies ... on the other hand, the ordinary man will make to himself every excuse He will contemn money-making as a sordid aim, readily exaggerating itself into a vice; he will dwell upon the obligations and...
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The Project Gutenberg E Book of Domestic Animals, by Richard L. Allen ppt
... Cleveland bay, Belfounder Eclipse, American points of habits breeding management of colts breaking longevity, feeding Diseases glanders 140 142 143 143 144 145 141 146 147 148 149 150 151 1 54 ... 1 54 lampas, heaves, &c catarrh or distemper, spasmodic colic flatulent colic inflammation of bowels physicking worms bots wind-galls the fetlock cutting sprain of the coffin-joint— ringbone enlargement ... perpetuate in the offspring 2d These qualities, technically called points, should be inbred in the animals as far as practicable, by a long line of descent from parents similarly constituted The necessity...
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Báo cáo lâm nghiệp: "Soil environment and nutrient status of Norway spruce (Picea abies [L.] Karst.) underplantings in conditions of the 8th FAZ in the Hrubý Jeseník Mts" potx
... content in needles of healthy trees is in the range of 4 6 g·kg–1 (Fig 1) and it decreases below the limit value of g·kg–1 in 50% of the plots K content in needles of damaged trees is statistically ... (1993): Effects of drought on the yellowing status and the dynamics of mineral elements in the xylem sap of declining spruce (Picea abies [L. ] Karsten) Plant and Soil, 150: 303–306 D L. , KŪ ... the limit of the lower optimum of 130 mg·kg–1 In the subsequent organomineral horizon (Ae/Ep) the values of Ca indicate the lower optimum reserves in the range of 80–160 mg·kg–1, and in 15% of...
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Báo cáo lâm nghiệp: "Influence of exogenous L-proline on embryogenic cultures of larch (Larix leptoeuropaea Dengler), sitka spruce (Picea sitchensis (Bong.) Carr.) and oak (Quercus robur L.) subjected to cold and salt stress" pdf
... addition, intracellular proline levels are correspondingly low When proline is added, intracellular proline levels recorded correspond approximately to the amount of proline added to each culture ... cold and salt stresses, cultures were maintained for 14 days Every days, the flasks were briefly removed from the orbital shaker, the cells allowed to settle for 10 and the volume of settled cells ... Effect of NaCl salinity on growth and mineral partitioning in Quercus robur L. , a rhythmically growing species, Trees 12 (1998) 42 4 43 0 [2] Aspinall D., Paleg L. G., Proline accumulation: physiological...
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Báo cáo lâm nghiệp: " Influence of repeated defoliations by insects on wood increment in common oak (Quercus robur L)" pps
... iv) the relationship between radial increment and a single defoliation was much closer in the upland and floodplain stands (correlation coefficients around 0 .48 and 0.62, respectively) than in the ... lowest in the floodplain and riverbank stands Since the crowns are more frequently damaged by insects in floodplain stands, these latter have probably developed a defence mechanism, in principle ... Bohin and E Dreyer for help in organizing his participation in the meeting in Nancy, France the floodplain stand presenting the highest ratios and most severe decreases, and the solonetz, the lowest...
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Báo cáo khoa học: "A comparison of photosynthetic responses to water stress in seedlings from 3 oak species: Quercus petraea (Matt) Liebl, Q rubra L and Q cerris L" doc
... all PFD, water stress resulted in lower values of ΔF/F in Q petraea and Q rubra m’ Lower ΔF/F in stressed individuals was m’ probably induced by low CO availability at the chloroplast ... chlorophyll contents, leaf-specific weight and leaf optical properties could partly explain these differences in A Lin and Ehleringer (1982) reported that changes in spectral properties of leaves of ... visible light Annu Rev Plant Physiol 35, 15 -44 Schulze ED, Hall AE (1982) Stomatal responses, water loss and CO assimilation rates of plants in contrasting environments In: Physiological Plant...
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