its relevance to physics

Báo cáo y học: "The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis" pot

Ngày tải lên : 09/08/2014, 01:24

... transfected either with vector alone or together with CMV.hPARN.flag; vector DNA (BS+) was added to each transfection to make the total amount of co-transfected DNA µg per plate Cytosolic extracts were ... protein behavior except to say that the absence of this phosphorylation site did not seem to affect TTP’s ability to translocate from the nucleus to the cytosol in response to stimuli such as serum ... several interesting insights into regulatory molecules and pathways In addition to these crosses into specific knockout mice, we are crossing the TTP deficiency genotype into other genetic backgrounds...

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Báo cáo y học: "The organisation of the stress response, and its relevance to chiropractors: a commentary" pdf

Ngày tải lên : 13/08/2014, 14:20

... is to inhibit the production of proinflammatory cytokines such as tumor necrosis factor (TNF)-A, interferon (IFN)-Y and interleukin-12 (IL-12), and to stimulate the production of anti-inflammatory ... cycles and manifestations of autoimmune/allergic and inflammatory diseases that follow estradiol fluctuations Metabolic function Stress is understood to contribute to the pathogenesis of disease, ... and somato-sensory neurons have been associated as carriers of autonomic signals to the hypothalamus Signals may directly project to the hypothalamus, or indirectly through secondary autonomic...

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Báo cáo sinh học: "The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery" pptx

Ngày tải lên : 14/08/2014, 19:22

... active 3) The PHSC is notoriously difficult to transduce with oncogenic retroviral vectors and the protocol used was designed to enhance transduction by using multiple cytokines to stimulate division ... (86) to transduce PHSC with shorter exposure to less cytokines needs to be fully explored 6) In general the limitations of vectors should be taken into account when designing gene therapy protocols ... vectors to be repaired during virus production these vectors need to be further developed, especially for vectors derived from strongly oncogenic viruses In addition, inadvertent transfer to, ...

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Protein s nitrosylation and its relevance to redox control of cell signaling

Ngày tải lên : 09/09/2015, 17:56

... respiratory burst in response to microorganisms or inflammatory mediators (Babio BM et al, 2002) The enzyme complex consists of six subunits- two membrane-bound components, p91phox, p22phox which together ... whereas regulatory subunits scatter in the cytosol Upon activation, cytosolic components are recruited to the membrane and form a mutually stabilizing complex with membrane catalytic subunits The sequence ... heart-felt thanks to my lab members for listening to both of my happy and frustrating stories Spending time together with them has made my life in the lab most enjoyable I want to thank Luo Le...

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Characterization of the secretion of mesenchymal stem cells and its relevance to cardioprotection

Ngày tải lên : 10/09/2015, 08:42

... myocardial cell loss Ironically, reperfusion itself is an important contributor to irreversible myocardial cell loss due to a phenomenon referred to as reperfusion injury7 Based 13 on studies ... physical size of cardioprotective factor to 100-220 ηm, which is much larger than the typical paracrine mediators that usually consist of growth factors, cytokines and chemokines77 Under the transmission ... allosteric activator of phosphofructokinase, which catalyzes the commitment to glycolysis79, was shown to be present in the phosphorylated form This predicted that exposure of cells to exosome could...

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Geometric algebra and its application to mathematical physics c doran

Ngày tải lên : 17/03/2014, 14:29

... individual rotors are used to represent rotations, we must look at their composition law Let the rotor R transform the unit vector a into a vector b, ~ b = RaR: (1:86) Now rotate b into another vector ... plane by 90 , but forms trivectors (volumes) with vectors perpendicular to it The trivector 1^ 2^ commutes with all vectors, and hence with all multivectors The trivector (pseudoscalar) also has ... the commutator product of two bivector blades results in a third bivector It follows that the space of bivectors is closed under the commutator product, and hence that the bivectors (together with...

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Geometric Algebra and its Application to Mathematical Physics potx

Ngày tải lên : 29/06/2014, 06:20

... individual rotors are used to represent rotations, we must look at their composition law Let the rotor R transform the unit vector a into a vector b, ~ b = RaR: (1:86) Now rotate b into another vector ... plane by 90 , but forms trivectors (volumes) with vectors perpendicular to it The trivector 1^ 2^ commutes with all vectors, and hence with all multivectors The trivector (pseudoscalar) also has ... the commutator product of two bivector blades results in a third bivector It follows that the space of bivectors is closed under the commutator product, and hence that the bivectors (together with...

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Development of the Quantitative PCR Method for Candidatus ‘Accumulibacter phosphatis’ and Its Application to Activated Sludge

Ngày tải lên : 05/09/2013, 09:38

... from activated sludge was diluted to 0.5 ng µL-1 using sterilized distilled water The higher DNA concentration tended to cause difficulty to determine Ct value due to high and unstable baseline of ... highly sensitive and rapid tool for its quantification in activated sludge It would be suitable for routine monitoring or measurement of a large number of samples, and lead to better understanding ... samples were from 1.2×104 to 2.4×106 copies per reaction and from 0.9 to 31.5 % of PAOMIX positive cells, respectively These results revealed that quantitative PCR method is able to quantify most of...

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A guide to physics problems

Ngày tải lên : 19/01/2014, 11:52

... Bowl (Stony Brook) Fast Particle in Bowl (Boston) Mass Orbiting on Table (Stony Brook, Princeton, Maryland, Michigan) Falling Chimney (Boston, Chicago) Sliding Ladder (Princeton, Rutgers, Boston) ... Attenuation (Stony Brook) Electrons and Circularly Polarized Waves (Boston) Classical Atomic Spectral Line (Princeton, Wisconsin-Madison) Lifetime of Classical Atom (MIT, Princeton, Stony Brook) ... Bowl (Stony Brook) Fast Particle in Bowl (Boston) Mass Orbiting on Table (Stony Brook, Princeton, Maryland, Michigan) Falling Chimney (Boston, Chicago) Sliding Ladder (Princeton, Rutgers, Boston)...

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A guide to physics problems part 2

Ngày tải lên : 19/01/2014, 11:54

... of Toronto, and Yale Most of the schools that give such an exam were vii viii Preface happy to trust us with their problems We wish to thank the Physics Departments of Boston University (Boston), ... required to describe the motion of a diatomic rotor confined to a plane 4.44 Diatomic Molecules in Three Dimensions (Stony Brook, Michigan State) Consider the free rotation of a diatomic molecule ... State) 5.41 Rotator in Field (Stony Brook) 5.42 Finite Size of Nucleus (Maryland, Michigan State, Princeton, Stony Brook) Perturbation (Princeton) 5.43 U and 5.44 Relativistic Oscillator (MIT, Moscow...

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Tài liệu Báo cáo khoa học: "Organizing Encyclopedic Knowledge based on the Web and its Application to Question Answering" ppt

Ngày tải lên : 20/02/2014, 18:20

... related to technical terms collected from the Class II examination in the autumn of 1999 The objective here is not only to evaluate the performance of our QA system itself, but also to evaluate ... related to how and why, so as to enhance Webbased natural language understanding Acknowledgments The authors would like to thank NOVA, Inc for their support with the Nova dictionary and Katunobu Itou ... dictionary entries to estimate P (t|c) and P (t), which are relative frequencies of t in c and all the domains, respectively We used the ChaSen morphological analyzer (Matsumoto et al., 1997) to extract...

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Tài liệu Báo cáo khoa học: "AUTOMATIC SPEECH RECOGNITION AND ITS APPLICATION TO INFORMATION EXTRACTION" pdf

Ngày tải lên : 20/02/2014, 18:20

... and trigrams, has been a very powerful tool, so it would be very effective to extend its utility by incorporating semantic knowledge It would also be useful to integrate unification grammars and ... language models that use news manuscripts written prior to broadcasting To cope with this problem, we introduced filled-pause modeling into the language model is the reading-dependent language ... broadcast news has leveraged its value into areas of research well beyond speech recognition In the DARPA project, the Spoken Document Retrieval (SDR) of TREC and the Topic Detection and Tracking...

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Tài liệu Báo cáo Y học: Importance of the amino-acid composition of the shutter region of plasminogen activator inhibitor-1 for its transitions to latent and substrate forms pdf

Ngày tải lên : 22/02/2014, 07:20

... low-molecular-weight inhibitor of plasminogen activator inhibitor type by site-directed mutagenesis Biochemistry 37, 1227–1234 50 Friederich, P.W., Levi, M., Biemond, B.J., Charlton, P., Templeton, D., van ... The amount of active PAI-1, and thus the speciﬁc inhibitory activity, was calculated from the total amount of PAI-1 that had to be present to inhibit half of the uPA activity in the assays PAI-1 ... is identical to that of CP-9, A/G/H is identical to that of heparin cofactor II, while the S/A/S composition is present in angiotensinogen [1,3] The investigated residues according to the PAI-1...

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Geometric Algebra and Applications to Physics doc

Ngày tải lên : 05/03/2014, 11:21

... r = s Factorization: In geometric algebra there is a type of factorizing an r -graded multivector into an outer product of vectors We see how a nonzero bivector B can be factorized into an outer ... restriction to the shape of the plane It is to be noted that the bivector a ∧ b is different from the usual vector product a × b, which is an axial vector in Gibbs’ vector algebra P1: Binaya Dash October ... factorization of the bivector B into an outer product of orthogonal vectors with the condition (2.12) that the unit vector a be a factor of B Equation 2.13 tells us that b is a unique factor...

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The Savings and Loan Crisis and Its Relationship to Banking pptx

Ngày tải lên : 06/03/2014, 10:20

... does not have too much influence over its regulators and if the regulators have the ability to hire, train, and retain qualified staff In this regard, the bank regulatory agencies need to remain ... year-end 1982 to year-end 1985 was characterized by extremely rapid growth, as the industry responded to the new regulatory and legislative climate Total S&L assets increased from $686 billion to $1,068 ... were able to buy political favor in order to keep regulators from interfering in their operations 180 History of the EightiesLessons for the Future Chapter The Savings and Loan Crisis and Its Relationship...

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Báo cáo khoa học: N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding pptx

Ngày tải lên : 06/03/2014, 22:21

... not completely understood The HFE primary sequence exhibits signiﬁcant homology to major histocompatability complex (MHC) class I molecules and the protein is organized into a1, a2 and a3 structural ... binding and presentation to CD8 + cytolytic T cells In HFE, the proximity of the two a helices and the presence of amino acid side chains that project into the groove appear to prevent peptide binding ... discovered it was reported to co-localize and interact with the type transferrin receptor (TfR1) [5,18] TfR1 mediates the endocytosis of iron-loaded transferrin into acidic endosomes where the...

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Báo cáo khoa học: Activator-binding domains of the SWI ⁄ SNF chromatin remodeling complex characterized in vitro are required for its recruitment to promoters in vivo pot

Ngày tải lên : 07/03/2014, 00:20

... similarly to its recruitment to GAL1-10 and GAL2 The activator-binding domains of Swi1 and Snf5 are required for galactose-induced expression of SWI ⁄ SNF-dependent genes It was next necessary to determine ... by the same activator We chose to study the GAL regulon, which is known to be regulated by the Gal4 activator protein We ﬁrst tested a group of known Gal4 target genes [38] to identify a group ... recruitment to promoters M E Ferreira et al tional activators and general transcription factors to target genes [1,16–18] However, the abundance of the SWI ⁄ SNF complex was found to be low [1],...

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Báo cáo khoa học:The principle of flux minimization and its application to estimate stationary fluxes in metabolic networks docx

Ngày tải lên : 07/03/2014, 15:20

... oxidative pentose phosphate pathway had to be reversed to maintain the target fluxes Then, the NADPH needed to drive the reactions of the oxidative pathway into a backwards direction and to form hexose ... pathway 46 acetyl-CoA fi acetoac-CoA + CoA 47 Acetoac-CoA + NADPH fi 3HB-CoA + NADP 48 3HB-CoA fi PHB + CoA 49 PHB fi 3HB 50 Acetoac + NADH fi 3HB + NAD 51 Acetoac-CoA + Succ fi acetoac + Succ-CoA 52 Crot-CoA ... depolymerase b-hydroxybutyrate dehydrogenase Acetoacetate-succinyl-CoA transferase D-crotonase L-crotonase Acetoacetyl-CoA reductase (NADH) Crotonyl-CoA reductase Unknown pathway Propionyl-CoA...

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Báo cáo khoa học: Characterization of a cathepsin L-associated protein in Artemia and its relationship to the FAS-I family of cell adhesion proteins pot

Ngày tải lên : 07/03/2014, 16:20

... KCl, mM dithiothreitol and 10 mM MgCl2) using a motorized mortar and pestle (Torsion Balance Co, Clinton, NJ, USA) Following centrifugation to remove nuclei, yolk platelets, mitochondria (10 000 ... thought to represent destabilizing elements leading to rapid deadenylation and messenger breakdown [47,48] Thus, while CLAP appears to be somewhat refractory to protease degradation, its mRNAs ... high state of purity However, dissociation of CLP to its subunits (CL and CLAP) required incubation of CLP at pH for at least h at °C prior to chromatography on Mono S Dissociation of CLP could be...

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Báo cáo khoa học: "Bayesian Synchronous Tree-Substitution Grammar Induction and its Application to Sentence Compression" pdf

Ngày tải lên : 07/03/2014, 22:20

... rule c → e, and K is the total number of ways to rewrite c, we now take into account our DP(αc , P0 (· | c)) prior in (1), which, when truncated to a ﬁnite grammar, reduces to a K-dimensional Dirichlet ... from nodes in es to nodes in et or We therefore sample in the direction from source to target In particular, we visit every tree pair and each of its source nodes i, and update its alignment by ... sampling procedure is prone to local modes In order to counteract this and to improve mixing we used simulated annealing The probability mass function (5-7) was raised to the power 1/T with T dropping...

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