ion concentrations and light induced ion movements in the insect retina
Báo cáo hóa học: "Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat" doc
... our group indicating the secretagogue properties of the tachykinins substance P, neurokinin A, and neurokinin B in the same model Nevertheless and unlike our previous results, neurokinin B exerted ... P, neurokinin A, and neurokinin B also significantly increased tracheal mucus secretion In contrast to the inhibition of PAF induced secretion, montelukast did not modulate tachykinin stimulated ... influence the neurokinin A induced increase of tracheal secretion (neurokinin A + montelukast: 127 ± 9%) The effect of montelukast on neurokinin B induced tracheal mucus secretion is presented in figure...
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báo cáo khoa học: " Cold- and light-induced changes in the transcriptome of wheat leading to phase transition from vegetative to reproductive growth" pot
... of TaAGL42 increased, principally in leaf tissue, in the winter varieties and showed no response in Paragon If these two MADS-box genes are involved in cold induced phase transition, their profiles ... occur during the winter in a northern climate – a gradual decline in temperature, day-length and light intensity In most previous studies, unnaturally high light intensities have been maintained ... length and light quality) and internal (gibberellin and autonomous pathways) cues The different pathways, each responding to their own cues and each promoting or repressing flowering depending on the...
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Báo cáo y học: "A pilot study of rizatriptan and visually-induced motion sickness in migraineu"
... created the randomization scheme by drawing treatment assignments from a blinded container The investigator administering the drug, the technicians performing testing, and the subject were blinded ... Every minutes during the N trial, subjects were asked to rate their motion sickness and anxiety During the H condition, minutes after beginning stripe viewing, the subject’s non-dominant hand was ... visually -induced motion sickness We were especially interested in replicating and extending research by Drummond and Granston that showed that visually -induced motion sickness in migraineurs can...
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Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf
... cloned into pBluescript SK+, resulting in plasmid pIM3980 Double stranded sequence was determined for a region of this construct containing galA and some of the flanking regions, resulting in the ... by introducing an NsiI site at the translation start point of galA and by then cloning a fragment, starting at this NsiI site and containing the galA gene and approximately 700 bp 3¢-flanking ... detected in the presence of D-galacturonic acid and L-arabinose The expression of galA is very low on the inducing compounds Using approximately 50 ng of the PCR product for labelling, the radiation...
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Báo cáo khoa học: The association of heavy and light chain variable domains in antibodies: implications for antigen specificity pot
... specific for the type of interface The remaining five positions (L41–L44 and L36) are instead located at the interface between the two chains, and the difference in the amino acids occupying them is ... L55 and H57 and of residues L24 and H25 (which are the furthest structurally conserved residues in the antigen-binding site) and between the Ca of residue 36 of the light chain and of the last insertion ... by the Gini index analysis in the structure dataset The height of the letters is proportional to the frequency of the corresponding amino acid in the position indicated on the x axis The letters...
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Báo cáo sinh học: " Motavizumab, A Neutralizing Anti-Respiratory Syncytial Virus (Rsv) Monoclonal Antibody Significantly Modifies The Local And Systemic Cytokine Responses Induced By Rsv In The Mouse Model" pdf
... either at a very low level or were below the level of detection of the assay in the non-infected control group, and the objective of the study was to evaluate the effect of motavizumab in the inflammatory ... of the administration of the anti-RSV antibody had no effect on the cytokine profile or other clinical and inflammatory parameters evaluated, therefore those controls were not included in the ... role in RSV infection, others have related the RSV -induced lung damage to the overproduction of TNF-α [10,11] In our previous studies, palivizumab administration did not modify BAL concentrations...
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Báo cáo hóa học: " Motavizumab, A Neutralizing Anti-Respiratory Syncytial Virus (Rsv) Monoclonal Antibody Significantly Modifies The Local And Systemic Cytokine Responses Induced By Rsv In The Mouse Model" potx
... either at a very low level or were below the level of detection of the assay in the non-infected control group, and the objective of the study was to evaluate the effect of motavizumab in the inflammatory ... of the administration of the anti-RSV antibody had no effect on the cytokine profile or other clinical and inflammatory parameters evaluated, therefore those controls were not included in the ... role in RSV infection, others have related the RSV -induced lung damage to the overproduction of TNF-α [10,11] In our previous studies, palivizumab administration did not modify BAL concentrations...
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Báo cáo khoa học: "Comparative study of PM2.5 - and PM10 - induced oxidative stress in rat lung epithelial cells" pptx
... containing PM10 and the other filter containing PM2.5 Preparation and extraction of filters Teflon filters were baked for h at 100oC and transferred into 50 ml conical tube with the particles facing ... change in PM10-treated group As shown in Fig and 10, no distinct changes were detected in the expression of Mn-SOD mRNA and Cu/Zn-SOD mRNA In the cells treated with µg/cm2 of PM2.5 and PM10, the ... Jun-B, and Jun-D) proteins that bind with antioxidant response element (ARE) and regulate expression and induction of NADPH:quinone oxidoreductase and glutathione-S-transferase gene, encoding antioxidant...
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Báo cáo y học: "Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration" docx
... funding, participated in the design of the study and the interpretation of data, and assisted in the preparation of the final manuscript JAH conceived the study, secured funding, contributed to the ... to the design and coordination of the study, and participated in the interpretation of data and extensive preparation of the final manuscript All authors read and approved the final manuscript ... caveolin-1 and p16INK4a gene expression p16INK4a is a cyclin-dependent kinase inhibitor that prevents retinoblastoma phosphorylation and arrests the cell cycle in the G0/G1 phase prior to entry into...
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Báo cáo y học: "The origin and early evolution of eukaryotes in the light of phylogenomics" doc
... [28,69], the spliceosome [29], the RNA interference machinery [70], the proteasome and the ubiquitin signaling system [71], and the endomembrane apparatus [10] The outcomes of these reconstructions ... Transcription and translation are coupled in Archaea Mol Biol Evol 2007, 24:893-895 109 Koonin EV: The origin of introns and their role in eukaryogenesis: a compromise solution to the introns-early ... the same time (as shown in Figure 1) selective force behind the evolution of the nucleus, and in particular the elaborate nuclear pore complex The nucleus disrupts the transcription-translation...
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Curcumin modulates dopaminergic receptor, CREB and phospholipase c gene expression in the cerebral cortex and cerebellum of streptozotocin induced diabetic rats potx
... expression which is crucial in maintaining the normal neuronal function and survival in diabetes The dopamine D1 signal transduction pathway, activation of the transcription factor CREB, and dopamine-mediated ... supplementation influenced the functional regulation of these receptors to maintain normal dopaminergic function and this might also be involved as a mechanism of preventing cerebellar dysfunctions The interest ... hrs after the administration of morning dose of insulin and curcumin The results were expressed in terms of milligram per decilitre of blood Total Dopamine receptor binding studies in the cerebellum...
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Báo cáo y học: "Presence of the CYP2B6 516G T polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patients" pptx
... despite the close linear relationship between plasma EFV concentrations at these time points and trough concentrations [27] Evidence for the use of this therapeutic range in assessing the relation ... resulted in lowering of EFV concentrations towards the therapeutic range and an improvement in CNS related symptoms in the majority of these patients In our study, the median EFV concentration for the ... correlations between the presence of the TT genotype and higher intra and extracellular EFV concentrations and between the presence of the single nucleotide polymorphism (SNP) and increased incidence...
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Báo cáo y học: "Silencing CD36 gene expression results in the inhibition of latent-TGF-β1 activation and suppression of silica-induced lung fibrosis in the rat" pdf
... instillation and in the histological and immunohistochemical experiments JC initiated the project, participated in the design of the study and in the interpretation of data, and revised the manuscript ... those of the silica and silica+Lv-shCD36-NC groups [see Additional file and Additional file 3] At the three time points after the instillation, the IOD average of collagen I in the silica and the ... Lv-shCD36-NC in physiological saline, was instilled into the lungs using a 14-gauge needle inserted into the trachea through the epiglottis of the larynx The site of surgery was sutured and the rats...
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Báo cáo y học: " Antenatal and postnatal corticosteroid and resuscitation induced lung injury in preterm sheep" pot
... bronchial epithelium with ventilation and induced in the smooth muscle surrounding the larger airways The Betamethasone group also lost the bronchial epithelium mRNA but there was no induction in the ... birth initiates an inflammatory cascade characterized by inflammatory cell influx into the lungs, increased alveolar protein, inflammatory cytokine mRNA induction, and systemic acute phase inflammatory ... different effects In our model, both betamethasone and dexamethasone decreased the induction of the pro-inflammatory cytokines MCP-1 and IL-1β In preterm sheep, the initiation of ventilation leads to...
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Báo cáo y học: "Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice" pps
... ing the extent of the initial toxicity and vascular injury induced by MCTp We first investigated whether lung cell colonization could account for the protective effects of BMDCs To minimize the ... determined from these studies In our study, BMDCs injection did not improve hypoxia -induced PH, suggesting a limited role as compared to MCTp -induced PH PCR : polymerase chain reaction In conclusion, ... described [16] After fixation and paraffin embedding, µm-thick lung sections were cut and stained with hematoxylin-phloxine-saffron In each mouse, 30 intraacinar vessels accompanying alveolar ducts...
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Báo cáo khoa học: "Diet-induced bacterial immunogens in the gastrointestinal tract of dairy cows: Impacts on immunity and metabolism" ppsx
... translocation occurs mainly in the intestines Epithelium in the intestines is of a monolayer structure with tight junctions at the apical pole of the cells In the study of Chin et al [25] using intestinal ... grain, the E coli count was further increased Grain feeding (90% grain in the diet) increased the numbers of anaerobic bacteria in the colon by 1000-fold It is also worth mentioning that other ... Interestingly, the corresponding DM intake in their study was 13.33, 15.28, 14.68 and 16.04 kg/d, respectively, and increasing the amount of barley grain in the diet significantly increased DM intake...
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Báo cáo y học: "A novel model of common Toll-like receptor 4- and injury-induced transcriptional themes in human leukocytes" pot
... TLR4 -induced inflammation resulting from endotoxin infusion, and those differentially expressed in PBL in the early posttrauma time period Differential gene expression in PBL during prolonged injury ... opiates and other therapeutics since these agents were not utilized in the endotoxin challenged subjects While we cannot completely exclude interacting effects from interventions and therapies, the ... expression in PBL first noted during systemic inflammation induced by TLR4 activation [16] persists for an extended period in patients with injury induced systemic inflammation Conclusions Gene-expression...
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Sailfish habitat utilization and vertical movements in the southern gulf of mexico and florida straits
... concurrent increase in our understanding of fishing gear behavior, including movements and effective fishing depths The combined use of these technologies to describe both vertical short-duration movements ... as the minimum straight-line distance (MSLD) traveled between the initial tagging location and the location of the first reliable satellite contact with the detached tag (inferred as the location ... and short-duration movements, interpolated temperatures and depth tracks were then superimposed using the archived depth and temperature data recorded during the vertical movements of these individual...
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High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 1
... polishing along the [010]pc direction and (b) after repolishing in the [110]pc direction Arrows indicate the direction of polishing Note the realignment from (a) to (b) (c) The domain patterns in the ... transformations during cooling of the crystal to room conditions The resultant RSM pattern is given in (b)-(d) In the actual mapping, the detected diffractions are restricted to within the region of ... result of the constructive interference effect of the nanotwin diffractions One such peak lies along the line joining the two parent nanotwin diffractions, of which the exact position is determined...
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High resolution x ray diffraction study of phase and domain structures and thermally induced phase transformations in PZN (4 5 9)%PT 2
... saddle point in the mapping except that the said saddle point remains not well-defined in the mapping in Figure 5.3(b) Lastly, should it represent a new phase, then (4) there is a wide spread in its ... typically decreasing continuously with decreasing 2θ value in the mapping; (2) in addition to the extended spreading in the ω = 0° plane, the “shoulder” also spreads out onto the ω ≠ 0° plane ... peak in the range of 2θ ≈ 43.0-44.0º The major peak relates to the (002) R phase, and will be represented by (002)R in our further discussion The origin of the minor broad peak lying at the lower...
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