ion channel link in cancer an alternative opportunity for diagnosis and therapy
Tài liệu Biomarkers in Cancer: An Introductory Guide for Advocates pdf
... transcription and translation Major Steps in Making a Protein From DNA Transcription: copying the DNA sequence Translation: changing the DNA sequence into a protein Image credit: National Institute ... genes can increase the chance of developing breast and other cancers in both men and women Individuals with these mutations can obtain more frequent screenings that may detect cancer in its early ... of invasive tumor cells show uniform, intense membrane staining IHC (Herceptest®) Scoring Breast Cancer Cell Staining pattern Score Interpretation No staining Negative Faint incomplete staining...
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Báo cáo y học: " Emergency medicine in Scandinavia - an outstanding opportunity for research" pdf
... Brabrand and Ekelund: Emergency medicine in Scandinavia - an outstanding opportunity for research Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2010 18:5 Submit your next manuscript ... specialties for financial support, and in both Denmark and Sweden many researchers have difficulties financing their projects Traditional grants are difficult to get, and EM is not an area of ... funding for EM research In the mean time we have to make with what we have, and perhaps also collect our own money A Scandinavian research fund for EM could be a solution, and small steps in this...
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Báo cáo y học: "Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer''''s disease" pot
... activation and subsequent increases in intracellular calcium, oxidative stress, and neurodegeneration [12] Other ion channels, including glutamate receptors, nicotinic cholinergic receptors, and ... Alternative splicing of ion channels in AD AD also revealed extensive alternative ion channel splicing No information has been reported to date regarding alternative splicing of ion channel genes associated ... relevant splicing changes to be pursued in further functional and mechanistic studies Disease-associated alternative ion channel splicing Alternative splicing of ion channels in mTLE The splice...
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Báo cáo Y học: An alternative model for photosystem II/light harvesting complex II in grana membranes based on cryo-electron microscopy studies pptx
... Rosenberg for his assistance with software and Dr S Prince, Dr S V Rue and Prof G Garab for useful suggestions and debate T D Flint is thanked for plant growth and specimen preparation as well ... composition of the sucrose density gradient fractions from Tris/urea-treated membranes as determined by SDS/PAGE and Coomassie staining The left lane shows band a and the right lane band c Molecular ... separation of grana membranes into fractions differing in density is possible No detergent is involved in this separation process, and the density gradient fractions can be recovered (after dilution)...
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Báo cáo khoa học: Cytoskeleton-modulating effectors of enteropathogenic and enterohemorrhagicEscherichia coli: role of EspL2 in adherence and an alternative pathway for modulating cytoskeleton through Annexin A2 function pot
... interaction may result in the aggregation of actin pedestals and the induction of membrane protrusions (Fig 1) An in vitro assay for the actin bundling activity of Annexin A2 clearly indicated enhancement ... signaling, cell adhesion, membrane trafficking, membrane–actin interactions and membrane-domain formation [19,20] At EPEC-adherent loci, cholesterol and glycosyl phosphatydilinositol-anchored proteins ... endocytosis and ion fluxes across the membrane [14] Annexin A2 binds directly and specifically to phophatidylinositol (4,5)-bisphosphate, and this binding is responsible for recruiting the Annexin A2–p11...
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báo cáo hóa học:" Pain in cancer. An outcome research project to evaluate the epidemiology, the quality and the effects of pain treatment in cancer patients" pptx
... pain in advanced cancer is about 70% with ample variations according to the cancer type and disease stage [2] Despite the existence of published and well-known guidelines for cancer pain management ... strategies, and called for a prospective program of research aimed at making available to treating physicians, patients and families valid information about pain management in cancer Two main lines ... (internet) resources for people interested and/ or involved in issues related to cancer pain [13]; b) drug utilization and appropriateness: an evaluation of the volume and quality of prescriptions...
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Báo cáo y học: "An improved method for detecting and delineating genomic regions with altered gene expression in cancer" ppsx
... uniquely defined for any partitioning, meaning that finding u* is reduced to finding an optimal partitioning of I which can be performed efficiently The limitation is that we pendently and identically ... expression maps and derive efficient algorithms for its computation In systematic evaluations, we show that segmentation by TV minimization combines enhanced detection performance with an enhanced ... on TV minimization The value of this method lies in that it combines significantly improved detection performance with an enhanced ability to delineate relevant regions The explanation for these...
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The phenomenon of evaporative cooling from a humid surface as an alternative method for air-conditioning
... combined with another system such as a direct expansion coil (DX), resulting into a more economic solution than installing an only system In 1986, Anderson tested an air conditioning system using a direct ... wife [5] The first rigorous analysis of the direct and indirect evaporative systems, considering both the advantages and disadvantages and indicating and establishing some basis about their design, ... generated in contaminated plants nearby Uncontrolled conditions in plants are consequence of a default in the maintenance The bacteria feed from organic waste in water, and take refuge in incrustations...
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Pseudo vector control – an alternative approach for brushless DC motor drives
... the direct transformation and the invert one, the rotor position will be needed The instantaneous rotor position and speed can be obtained from the Hall-sensors information using an observer + ... on Hall-sensor signal showing the communication instants The torque ripple is therefore inevitable If we can incorporate other information of the drive into calculation of the reference currents ... transformation As previously mentioned, the zero-sequence current i0 is forced to be zero in our system, so only ed and eq need to be calculated using simplified Park’s transformation SIMULATION...
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Tài liệu Báo cáo khóa học: Suppression of b1,3galactosyltransferase b3Gal-T5 in cancer cells reduces sialyl-Lewis a and enhances poly N-acetyllactosamines and sialyl-Lewis x on O-glycans Lydia Mare and Marco Trinchera pdf
... expression and secretion Moreover, only cell lines expressing b3Gal-T5 express the antigen, and cells not expressing are forced to by cDNA transfection On the other hand, sLea synthesis and secretion ... b3Gal-T5 repression in a similar manner as those carried by membranebound molecules b1,3Gal-T activity, b3Gal-T5 transcript levels, and sLea expression in cancer cell lines and recombinant clones ... according to published procedures [9,16,22], with some modifications Total lysates were obtained by boiling 10 in phosphate-buffered saline containing 0.5% SDS and 1.0% 2-mercaptoethanol, and spinning...
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When Someone You Know Has Cancer: AN ACTIVITY BOOKLET FOR FAMILIES pot
... org/dvd/html National Cancer Institute www .cancer. gov Information on many topics and concerns For tips on talking to children, go to www .cancer. gov/cancertopics/ when-someone-you-love-is-treated and click ... disease head-on American Cancer Society www cancer. org Learn about Relay for Life, Daffodil Days, and Making Strides Against Breast Cancer, and find dates for upcoming events in your area Massachusetts ... and click “Talking with Family and Friends.” CureSearch curesearch.org Information on childhood cancer for parents and families Dana Farber Cancer Institute: Family Connections www.dana-farber.org/pat/support/...
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RUBBER PRODUCTION IN LIBERIA: An Exploratory Assessment of Living and Working Conditions, with Special Attention to Forced Labor docx
... Assessment of Living and Working Conditions, with Special Attention to Forced Labor 11 Tapping rubber trees The clearing of land, breeding in the nursery, and the weeding and pruning of fields and young ... rebuilding strategy focuses on reintegration and rehabilitation Efforts include national and community infrastructure projects, training and education, promoting business development, health care, and ... changes, but that problems persisted, including inadequate schools and housing and sanitation, high quotas and very low wages, long hours, health and safety violations, and the continued reliance...
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SUPERVISORY, INSTRUCTIONAL SKILLS AND PROFESSIONAL PERFORMANCE OF TEACHERS IN VOCATIONAL COLLEGES IN NGHE AN PROVINCE: BASIS FOR DEVELOPING AN ENHANCEMENT PROGRAM
... by, for example, encouraging discussion, listening and responding to group interaction, and eliciting samples of student thinking orally and in writing Standard No 3: The teacher understands ... programs and activities and there is necessity for proper adjustment, and having punctuality and attendance as to top reference in measuring the performance of teachers, and human relation and personality ... training under the direction of standardization, modernization, socialization, democratization and international integration Improving the quality and developing the size of vocational training...
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báo cáo hóa học: "The use of body weight support on ground level: an alternative strategy for gait training of individuals with stroke" pptx
... second MANOVA; ankle, knee, and hip joint range of motion for the third MANOVA; and foot, shank, thigh, and trunk segmental range of motion for the fourth MANOVA When applicable, univariate analyses ... results for walking spatial-temporal parameters and for joint and segmental pattern and range of motion follow Temporal-spatial gait parameters Table depicts mean and standard deviation (± SD) ... 3.451,2 Mean (± SD) values for range of motion of ankle, knee, and hip joints, and foot, thigh, shank, and trunk segments during stride cycle in the three conditions (no harness, 0% of BWS, and 30%...
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báo cáo hóa học:" Mucins in ovarian cancer diagnosis and therapy" ppt
... mucins in ovarian tumors and their potential role in ovarian cancer diagnosis and treatment Mucins Being that 90% of ovarian cancers are of epithelial origin, mucins may be attractive candidates for ... repetitive domains of peptides rich in serine, threonine, and proline in their backbone Serine and threonine are sites for O- and N-glycosylation Presence of the tandem repeat domain which varies in number, ... ovarian cancer and ovarian cancer prognosis Use of Mucins in Radioimmunodiagnosis (RID) and Radioimmunotherapy (RIT) Monoclonal antibodies against mucins may have potential applications in improving...
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Báo cáo hóa học: " An alternative route for the synthesis of silicon nanowires via porous anodic alumina masks" potx
... removed and the pore diameter was widened by dipping the membrane in a wt.% H PO4 solution at 35°C for 20 The thickness of the freestanding porous alumina membrane was measured by field emission scanning ... spectra of Si 2p (a) and O 1s (b), and the corresponding deconvolution analysis The results obtained by XPS and EDX indicate that the Si NWs are constituted by Si 0, SiO2 , and substoichiometric ... were maintained in these conditions for 30 Finally, the flow of argon was readjusted to 1,000 mL min-1 and hydrogen was stopped After that, the cooling ramp was set at 20°C min-1 under flowing argon...
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Báo cáo khoa học: "Clostridium difficile-associated diarrhea in radiooncology: an underestimated problem for the feasibility of the radiooncological treatment" doc
... toxin A and B by enzyme immunoassay Since 2008 for all patients with any diarrhea longer than 24 hours were screened for CD toxin A and B In case of clinical suspicion of CDAD and negative findings ... data and drafted the manuscript MH was participating in identification of patients data OK participated in planning of the study and its coordination All authors read and approved the final manuscript ... in combination with weekly cisplatin for locally advanced head and neck cancer Head Neck 2005, 27:36-43 36 Chopra T, Alangaden GJ, Chandrasekar P: Clostridium difficile infection in cancer patients...
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Báo cáo y học: "An alternative methodology for the prediction of adherence to anti HIV treatment" ppt
... accurate and reliable information on the effectiveness and efficacy of the prescribed treatment regime To meet the need for having objective information on adherence, a method is proposed using VL and ... co-infection, nonadherence, drug use) The validity and reliability of selfreported information are questionable As yet there is no 'gold standard' for adherence measurement in HIV patients and ... benefit than the continued search for a single defining adherence measure Current methods can be divided into two forms: i) subjective, such as various self-report and interview based methods and ii)...
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báo cáo khoa học: " Government use licenses in Thailand: an assessment of the health and economic impacts" pptx
... Board of Investment of Thailand Figure Value of foreign direct investment interested in investing in Thailand between 2002 and 2008, by country (in million USD) Yamabhai et al Globalization and Health ... purchasing power of the buyer) [26] Instead, this study sought to investigate the changes in national exports and in the short- and long-term foreign investment flows into Thailand following the grant ... Finally, four licenses were granted in January 2008 for cancer drugs, letrozole, docetaxel, erlotinib, and imatinib (which are used in the treatment of breast and lung cancers, gastrointestinal...
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Báo cáo y học: " An integrated approach to diagnosis and management of severe haemoptysis in patients admitted to the intensive care unit: a case series from a referral centre" ppsx
... bleeding, bleeding of gastrointestinal and oropharyngeal origin, heart failure, intra alveolar haemorrhage and incomplete data For each patient, the following information were recorded: baseline ... Figure Initial management and short-term outcome Initial management and short-term outcome †Life sustaining therapy was withheld/withdrawn in 2/46 patients managed conservatively and in 10/147 ... conditions, initial clinical presentation and vital signs, laboratory tests results, chest radiography, fiberoptic bronchoscopy and CT scan findings when performed, severity of haemoptysis, and...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng 9 tr 25