intrahepatic liver progenitor cells
Báo cáo y học: "Translational control plays a prominent role in the hepatocytic differentiation of HepaRG liver progenitor cells" docx
... often impaired and liver progenitor cells, also called oval cells, significantly increase both in number and their capability to proliferate [2,3] In recent years, liver progenitor cells have drawn ... 1997, 151:1273-1280 Sell S, Ilic Z: Liver stem cells In Stem cells Edited by: Potten CS San Diego, CA: Academic Press; 1997:233-282 Matthews VB, Yeoh GC: Liver stem cells IUBMB Life 2005, 57:549-553 ... carcinoma (HCC) [14,15] These bipotent progenitor cells have been found to repopulate uPA/SCID mouse damaged livers [16] Throughout differentiation, HepaRG cells evolve from a homogeneous dedifferentiated,...
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Báo cáo sinh học: "Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation–a phase I study (MISOT-I)" doc
... involving treatment of liver transplant recipients with multipotent adult progenitor cells (MAPCs) with the goal of reducing the dose of immunosuppressive drugs and of supporting liver regeneration ... mesenchymal stem cells derived from adult marrow Nature 2002, 418:41-49 Reyes M, Verfaillie CM: Characterization of multipotent adult progenitor cells, a subpopulation of mesenchymal stem cells Ann ... survival of patients and liver grafts [1,2,12] This success of interdisciplinary transplant medicine has made liver transplantation a standard-of-care clinical therapy for end-stage liver disease Long-term...
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báo cáo hóa học:" Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation–a phase I study (MISOT-I)" pptx
... involving treatment of liver transplant recipients with multipotent adult progenitor cells (MAPCs) with the goal of reducing the dose of immunosuppressive drugs and of supporting liver regeneration ... mesenchymal stem cells derived from adult marrow Nature 2002, 418:41-49 Reyes M, Verfaillie CM: Characterization of multipotent adult progenitor cells, a subpopulation of mesenchymal stem cells Ann ... survival of patients and liver grafts [1,2,12] This success of interdisciplinary transplant medicine has made liver transplantation a standard-of-care clinical therapy for end-stage liver disease Long-term...
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Báo cáo khoa học: Hypoxia-driven proliferation of embryonic neural stem ⁄ progenitor cells – role of hypoxia-inducible transcription factor-1a ppt
... regulate the proliferation and differentiation of stem cells, and that, especially, mild hypoxia has salutary effects on stem ⁄ progenitor cells [12–14] Cytotrophoblasts proliferate at low O2 tensions ... neural stem cells derived from the embryonic mesencephalon (E13.5) were used in the present study Generally, neural stem cells were grown to form as neurospheres in vitro The ability of stem cells ... for proliferation of neural stem cells in vitro The passaged neurospheres were dissociated into single cells and planted in four-well plates at a density of · 104 cells per well, and then cultured...
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liver stem cells methods and protocols
... mammalian liver development, it is essential to separate hepatoblasts (fetal liver progenitor cells) from nonparenchymal cells, including stellate cells, endothelial cells, and hemopoietic cells ... the potential of these cells are discussed Key words: Liver stem cells, Liver progenitor cells, Hepatocyte transplantation, Bioarticial liver- assisted device Introduction Liver disease constitutes ... hepatic progenitor cells; (2) Hepatic differentiation from stem cells; (3) Bile ductal cell formation from stem cells; (4) Liver stem cells and hepatocarcinogenesis; and (5) Application of liver...
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báo cáo hóa học:" Circulating endothelial progenitor cells: a new approach to anti-aging medicine?" docx
... Schober A, Weber C: Adult progenitor cells in vascular remodeling during atherosclerosis Biol Chem 2008, 389:837-844 Zhao Q, Ren H, Zhu D, Han Z: Stem /progenitor cells in liver injury repair and ... mononuclear cells [127-129] Original thoughts regarding the use of bone marrow stem cells in infarcts revolved around studies showing "transdifferentiation" of various bone marrow derived cells into cells ... Cong X, Fei R, Chen HS, Wei L: Transplanted endothelial progenitor cells ameliorate carbon tetrachloride-induced liver cirrhosis in rats Liver Transpl 2009, 15:1092-1100 Nakamura T, Torimura T,...
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Báo cáo hóa học: " Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects" potx
... Additional file 1: Progenitor Cell Numbers Expressed as a Percentage of Peripheral Blood Mononuclear Cells The data provided represent number of progenitor cells (CD133, CD34, and cells with EPC ... mobilization of cells expressing hematopoietic stem cell markers Data is presented as percentage of mononuclear cells in Additional File Analysis of the number of the progenitor cells in circulation ... these cells Given the possibility that both hematopoietic stem cells and EPC may serve as endogenous “repair cells , we sought to assess a relatively non-invasive means of modulating these cells...
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báo cáo hóa học: " Inhibition of gap junctional Intercellular communication in WB-F344 rat liver epithelial cells by triphenyltin chloride through MAPK and PI3-kinase pathways" pdf
... inhibited significantly GJIC in WB-F344 liver cells The migration of Lucifer yellow dye in scraped WB F344 liver cells treated with TPTC was less than that in untreated cells, when the concentration was ... Cytotoxicity of TPTC in WB-F344 liver cell (A) Cell viability of WB-F344 liver cells after exposure to TPTC of different concentrations for 30 and 60 LC50 of TPTC in WB-F344 liver cells amounted to ± 0.9 ... various cells [23,58-62] To explore the potential role of PI3K signaling in the signaling processes involved in TPTC-induced disruption of GJIC in liver cells, we measured GJIC in rat liver cells...
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Transcoronary Transplantation of Progenitor Cells after Myocardial Infarction ppt
... (Transplantation of Progenitor Cells and Recovery of LV [Left Ventricular] Function in Patients with Chronic Ischemic Heart Disease) trial, we investigated whether intracoronary infusion of progenitor cells ... phases: a pilot trial comprising 17 patients (7 receiving progenitor cells derived from bone marrow [BMC] and 10 receiving progenitor cells derived from circulating blood [CPC]); a second phase, ... endothelial progenitor cells via the PI 3-kinase/Akt pathway J Clin Invest 2001;108:391-7 11 Vasa M, Fichtlscherer S, Adler K, et al Increase in circulating endothelial progenitor cells by statin...
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Báo cáo sinh học: " CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo" pdf
... cells in the SVZ and DG are doublecortin+ (DCX+) neuronal progenitors [44], and that other TUNEL+ cells include GFAP + cells (which may be stem cells or astrocytes [45]) and NG2+ progenitor cells ... neural cells (rat) 100 120 Primary neural cells (human) 20 40 60 80 Percent survival 100 120 Cancer cells Figure Primary CNS cells are more vulnerable to BCNU and cisplatin than are cancer cells Cells ... stem cells (NSC) give rise to glial-restricted precursor (GRP) cells and neuron-restricted precursor (NRP) cells NRP cells can give rise to multiple populations of neurons, whereas GRP cells...
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Báo cáo y học: "Identification of subpopulations with characteristics of mesenchymal progenitor cells from human osteoarthritic cartilage using triple staining for cell surface markers" docx
... cytometry analysis of cells Either isolated cells from OC were directly used for flow cytometric analysis or cells were used after adherence and cultivation, as described above Cells were washed ... differentiation by progenitor marker sorted and culture-derived OC cells (data not shown) Differentiation of OC derived cells into osteoblasts was induced in vitro by treating the cells with ascorbic ... human mesenchymal stem cells J Biomed Sci 2003, 10:228-241 Reyes M, Verfaillie CM: Characterization of multipotent adult progenitor cells, a subpopulation of mesenchymal stem cells Ann N Y Acad Sci...
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Báo cáo y học: "It’s all in the blood: circulating endothelial progenitor cells link synovial vascularity with cardiovascular mortality in rheumatoid arthritis" docx
... number and impaired function of endothelial progenitor cells Ann Rheum Dis 2005 [Epub ahead of print] Asahara T, Kawamoto A: Endothelial progenitor cells for postnatal vasculogenesis Am J Physiol ... following injection of bone marrow-derived mononuclear cells Indeed, the first description of EPC showed that peripheral bloodderived CD34-positive cells integrated into newly formed vessels in an ... ischaemia [2] Pluripotent stem cells (PSC) in the bone marrow give rise to haemangioblasts (HA), with the potential to differentiate into either haematopoietic stem cells (HSC) or endothelial cell...
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Báo cáo y học: "Reduced number and impaired function of circulating progenitor cells in patients with systemic lupus erythematosus" pot
... hematopoietic stem cells of bone-marrow origin, but is also expressed on mature vascular endothelial cells The second marker, CD133, is also expressed on hematopoietic progenitor cells, but not on ... definitions, and novel paradigms for defining endothelial progenitor cells Blood 2005, 106:1525-1531 Urbich C, Dimmeler S: Endothelial progenitor cells: characterization and role in vascular biology ... endothelial progenitor cells Ann Rheum Dis 2006, 65:157-163 30 Westerweel PE, Luijten RK, Hoefer IE, Koomans HA, Derksen RH, Verhaar MC: Haematopoietic and endothelial progenitor cells are deficient...
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Báo cáo y học: "Human palatine tonsil: a new potential tissue source of multipotent mesenchymal progenitor cells" pdf
... of tonsil-derived mesenchymal progenitor cells (T-MPCs) tonsil-derived mesenchymal progenitor cells (T-MPCs) (a) Histology Induced bone marrow-derived mesenchymal progenitor cell (BM-MPC) cultures ... mononuclear cells (PBMCs) (105 cells) were incubated for days with either μg/mL PHA or allogeneic stimulating PBMCs (1 × 105 cells) with or without bone marrow-derived mesenchymal progenitor cells ... mesenchymal progenitor cells (T-MPCs) of T cells neic as well as phytohemaglutinin (PHA)-induced proliferative response in a dose-dependent manner regardless of the species of T cells Responding...
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Báo cáo y học: " Lentiviral transduction of Tar Decoy and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macrophages" pdf
... transduced cells B thymocytes from Tar-CCR5Rz transduced cells Percent positive cells are indicated Representative samples from one mouse each are shown single positive CD4 and CD8 cells [24] ... animal Tar aptamer, could be achieved in CD34+ hematopoietic progenitor cells by using lentiviral vectors The transduced progenitor cells differentiated normally into mature thymocytes in vivo ... vector transduction Human fetal liver CD34+ hematopoietic progenitor cells (HPC) were purified by positive selection on a magnetic column using the Direct CD34 Progenitor Cell Isolation Kit from...
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Báo cáo y học: "Prenatal exposure of ethanol induces increased glutamatergic neuronal differentiation of neural progenitor cells" pot
... http://www.jbiomedsci.com/content/17/1/85 brain cells which may cause structural deformities or deficits within the brain Neural stem /progenitor cells (NPCs) are selfrenewable cells in the CNS NPC is able to ... induced by an abnormal development of the secondary progenitor population of the subventricular zone (SVZ), also known as basal progenitor cells (BP cells) [61-64] In a study using Xenopus embryo, ... increased by ethanol treatment (Figure 3D) Positive cells against vGluT1 were also positive against BrdU staining, suggesting that neural progenitor cells are differentiated into glutamatergic neuron...
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Báo cáo y học: " Enhanced self-renewal of hematopoietic stem/progenitor cells mediated by the stem cell gene Sall4" doc
... these Ly5.2+ cells were able to reconstitute granulocyte, T cells, and B cells, as well as immature blood cells, as indicated by expression of GR-1, CD4/8, B220 and Sca-1 in BM cells respectively ... GFP control cells was not detected When the number of infused cells was raised to × 105 cells, both Sall4A and Sall4B transduced cells repopulated of recipients, whereas GFP transduced cells did ... Sall4B expanded cells, × 10 15 WT-like B6.SJL Sall4B expanded cells, × 106 11 WT-like B6.SJL GFP-infected cells, × 106 15 WT-like 11 WT-like B6.SJL Number of injected cells GFP-infected cells, × 10...
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báo cáo khoa học: "Optical characterization of colloidal CdSe quantum dots in endothelial progenitor cells" pptx
... Technical notes on endothelial progenitor cells: ways to escape from the knowledge plateau Atherosclerosis 2008, 197:496-503 Kawamoto A, Losordo DW: Endothelial progenitor cells for cardiovascular ... Dot Conjugates for siRNA Delivery Bioconjugate Chem 2007, 18:1391-1396 Hirschi KK, Ingram DA, Yoder MC: Assessing identity, phenotype, and fate of endothelial progenitor cells Arterioscler Thromb ... cluster inside cell, (b) QD cluster inside cell, see Fig 2; (c) QD cluster outside cells; (d) QD cluster outside cells Molnár et al Journal of Nanobiotechnology 2010, 8:2 http://www.jnanobiotechnology.com/content/8/1/2...
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Báo cáo y học: " Profibrotic potential of Prominin-1+ epithelial progenitor cells in pulmonary fibrosis" docx
... therapeutically administered stem and progenitor cells Prominin-1 (CD133) is a membrane-associated glycoprotein present on hematopoietic stem and progenitor cells [19,20] Recently, we have described ... we addressed whether prominin-1+ cells represent a common progenitor for alveolar type II epithelial cells, fibroblasts and macrophages We expanded prominin-1+ cells from lung explants of C57Bl/6-EGFP ... of prominin-1+ cells Bleomycin promotes the accumulation of prominin-1+ progenitors in the injured lung Inflammation mobilizes and activates local or exogenous stem and progenitor cells We therefore...
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Báo cáo y học: " Peripheral infusion of rat bone marrow derived endothelial progenitor cells leads to homing in acute lung injury" pps
... repair cells stemming from the bone marrow [14] Indeed, bone marrow has become a recognized source for progenitor cells of several cell types [15], including EC [13,16,17], epithelial cells [13,18-23], ... Circulating progenitor cells regenerate endothelium of vein graft atherosclerosis, which is diminished in ApoE-deficient mice Circ Res 2003, 93:e76-e86 Sata M: Circulating vascular progenitor cells ... contributed by circulating progenitor cells Circulation 2003, 108:3122-3127 Peinado VI, Ramirez J, Roca J, Rodriguez-Roisin R, Barbera JA: Identification of Vascular Progenitor Cells in Pulmonary Arteries...
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