integrins focal complex fc amp focal adhesion fa
Báo cáo khoa học: Cleavage of focal adhesion proteins and PKCd during lovastatin-induced apoptosis in spontaneously immortalized rat brain neuroblasts ppt
... Among the family members of the Rho GTPases, RhoA is one of the most studied and has been implicated in the formation of stress fibres and focal adhesion complexes [15] Focal adhesion complexes ... of both FAK (106 ± 12% of intact FAK) and p130Cas (91 ± 11% of intact p130Cas) proteins Mevalonate alone had no effect on the integrity of focal adhesion proteins (101 ± 11% of intact FAK and ... assembly of focal adhesions and actin stress fibres in response to growth factors Cell 70, 389–399 16 Meredith JE Jr, Fazeli B & Schwartz MA (1993) The extracellular matrix as cell survival factor...
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Báo cáo khoa học: Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells potx
... endothelial growth factor regulates focal adhesion assembly in human brain microvascular endothelial cells through activation of the focal adhesion kinase and releated adhesion focal tyrosine kinase ... tyrosine phosphorylation: just the FAKs Trends Cell Biol 8, 151–157 17 Gilmore, A.P & Romer, L.H (1996) Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreased cell motility ... cytoplasmic proteintyrosine kinase that localizes to focal adhesion [13] FAK can be phosphorylated by growth factors and during formation of focal adhesions and spreading [14] GPCR agonists including...
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Tài liệu Báo cáo khoa học: His374 of wheat endoxylanase inhibitor TAXI-I stabilizes complex formation with glycoside hydrolase family 11 endoxylanases pptx
... endoxylanase mobility A niger endoxylanase complex TAXI-I TAXI-I pH D pH pH E mobility T longibrachiatum M2 endoxylanase complex TAXI-I complex pH F pH G H mobility complex B subtilis endoxylanase pH ... changes in interface charges are less critical for stabilization of the enzyme– inhibitor complexes of wild-type TAXI-I and endoxylanases from B subtilis or T longibrachiatum M2 as such complexes were ... Three scans in the far-UV (260–180 nm) were recorded for each protein sample and averages are reported The obtained ellipticities were expressed as molar ellipticities Pure protein samples of TAXI-I,...
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Báo cáo khoa học: The potyviral virus genome-linked protein VPg forms a ternary complex with the eukaryotic initiation factors eIF4E and eIF4G and reduces eIF4E affinity for a mRNA cap analogue ppt
... eIF4E–GSTÆVPg complex comparable to that observed from uninfected plants (Fig 5B) GSTÆVPg may be strongly challenged by the presence of viral VPg forms involved in complexes with the initiation factors ... with eIF4E in complexes associated with membrane fractions [25] In infected cells, a substantial amount of eIF4G may be involved in complexes with endogenous forms of VPg If these complexes are ... could remain bound to eIF4E even at high cap analogue concentrations The fact that m7GDP could not displace VPg argued in favour of the presence of a VPg-binding site on eIF4E, which is distinct...
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Báo cáo khoa học: "Treatment of bipolar disorder: a complex treatment for a multi-faceted disorder" pdf
... http://www.annals-general-psychiatry.com/content/6/1/27 Another factor which may perplex the design of a clinical trial and the interpretation of its results is the fact that the patients' clinical condition and ... oxcarbazepine; OFC, Olanzapine-fluoxetine combination; Olz, olanzapine; Quet, quetiapine; Ris, risperidone; SSRIs, Selective Serotonine Reuptake Inhibitors; TCA, Tricyclic antidepressant; Venf, venlafaxine; ... psychoeduation, family-focused psychoeducation and cognitivebehavioral therapy seem to be the most efficacious interventions for relapse prevention Moreover, they can help both the patient and family...
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Báo cáo y học: "Complex cytokine effects in a complex autoimmune disease: tumor necrosis factor in systemic lupus erythematosus" potx
... can counteract Fas may also be important in another regard Given that in several mouse strains mutations of Fas (lpr) or FasL (gld) cause severe lupus-like disease by preventing FasL-induced apoptosis ... TNF-receptor associated factor, and FLICE-like inhibitory protein [52–57] Rheumatoid arthritis synovial cells are just one example where TNF appears to use such pathways to block Fas-mediated programmed ... produce high levels of TNF by immune complexes [75] Since murine lupus like human SLE constitutes an immune complex- mediated disease and since large amounts of immune complexes are deposited in the...
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Báo cáo y học: "The integrins are a superfamily of cell adhesion receptors that bind to extracellular matrix ligands, cell-surface ligands, and soluble ligands. They are transmembrane α" ppsx
... example, the focal adhesion kinase/cSrc, and the small GTPases Ras and Rho) and adaptors (for example, Cas/Crk and paxillin) that assemble within dynamic adhesion structures, including focal adhesions ... mammalian integrins can be broadly grouped into laminin-binding integrins (α1β1, α2β1, α3β1, α6β1, α7β1, and α6β4), collagen-binding integrins (α1β1, α2β1, α3β1, α10β1, and α11β1), leukocyte integrins ... motifs in vivo However, integrins also recognize many non-RGD sequences in their ligands, such as the tripeptide LDV in the immunoglobulin superfamily member vascular cell adhesion molecule (VCAM-1),...
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Báo cáo khoa học: "Screening for bovine leukocyte adhesion deficiency, deficiency of uridine monophosphate synthase, complex vertebral malformation, bovine citrullinaemia, and factor XI deficiency in Holstein cows reared in Turkey" pptx
... Anatolia and Şanlıurfa (n = 125) located in South East Anatolia in Turkey were sampled at random Random sampling was done on the Holstein cows that were brought to Ankara and Şanlıurfa slaughterhouses ... e.g bovine leukocyte adhesion deficiency (BLAD), deficiency of uridine monophosphate synthase (DUMPS), complex vertebral malformation (CVM), bovine citrullinaemia (BC), and factor XI deficiency ... of bovine leukocyte adhesion deficiency (BLAD), deficiency of uridine monophosphate synthase (DUMPS), complex vertebral malformation (CVM), bovine citrullinaemia (BC) and factor XI deficiency...
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Tài liệu Báo cáo khóa học: A multi-protein complex containing cold shock domain (Y-box) and polypyrimidine tract binding proteins forms on the vascular endothelial growth factor mRNA Potential role in mRNA stabilization pptx
... major complex (CCV1) formed on the V1 probe and migrated in a similar position to the CC44a complex on the 44 RNA probe (Fig 2B) To verify that the CC44a and CCV1 complexes were the same, complexes ... affect the ability of transcription factors to bind to DNA [23] Broader role for CSD/PTB complexes in growth factor gene regulation We found that the CSD/PTB complexes binding to the VEGF 5¢-UTR ... Ladomery, M (1996) Masking of mRNA by Y-box proteins FASEB J 10, 435–443 29 Wolffe, A.P., Tafuri, S., Ranjan, M & Familari, M (1992) The Y-box factors: a family of nucleic acid binding proteins conserved...
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Tài liệu BREWERY AND WINERY ASTEWATER TREATMENT: SOME FOCAL POINTS OF DESIGN AND OPERATION pptx
... positive factor resulting from the applied high hydraulic upflow velocities is the selective washout of brewery solids, like kieselguhr, trub and yeast In order to meet stringent requirement of surface ... and Pujol, R., 1996, Activated sludge plant facing grape harvest period – a case study, Water Sci Technol 34(11):25 Coetzee, G., Malandra, L., Wolfaardt, G.M., Viljoen-Bloom, M., 2004, Dynamics ... treating brewery wastewater, Water Res 34(16):3943 Jay, A J., Parker, M L., Faulks, R., Smith, A C., Wilde, P J., Faulds, C B., and Waldron, K W, 2004, A systematic micro-dissection of brewer’s...
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Báo cáo khoa học: Covalent activation of heart AMP-activated protein kinase in response to physiological concentrations of long-chain fatty acids docx
... omitted from these assays Activation of a-2 AMPK by these fasting concentrations of NEFA was also seen in assays with AMP By contrast, with AMP present, a-1 AMPK appeared to be insensitive to palmitate ... parentheses AMPK activity (pmolÆmin)1 per mg of 13 000 g supernatant protein) a-1 Complexes a-2 Complexes Initial NEFA concentration in the perfusate Assayed without 200 lm AMP Assayed with AMP Zero ... hepatocytes [37] that AMPK could be activated following increased AMP generation by increased flux of fatty acid through fatty acyl-CoA synthetase However our measurements of AMP and AMP/ ATP not support...
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Báo cáo khoa học: Characterization of a cathepsin L-associated protein in Artemia and its relationship to the FAS-I family of cell adhesion proteins pot
... Dros-fasI (Drosophila fasciclin I, NP_732166), Ory-big-H3 (Oryctolagus, rabbit, transforming growth factor-b induced protein precursor, Q95215), Homo-osf2 (Homo sapiens, osteoblast specific factor ... could occur through the Fas I domains or putative GPI unit, if one exists in CLAP as it does in Drosophila fasciclin I and many other fasciclin-containing proteins [36,46] Fas I domains in proteins ... degree of homology with fasciclin I, an extracellular protein found in numerous organisms The first Fas I domain in clone spans 128 amino acids (45–173), while the second Fas domain spans 132 amino...
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Báo cáo khoa học: "Factorizing Complex Models: A Case Study in Mention Detection" pdf
... training data cannot be incorporated directly; this is an inherent deficiency of the AIO model To facilitate a fair comparison, we will incorporate it in an indirect way: we train a classifier C on the ... set is complex But 477 = Language Arabic Chinese English 2003 English 2004 p (x, y) log qλ (y|x) ˆ (x,y)∈T + p (x, y) log qλ (y|x) ˆ (2) (x,y)∈T The only technical problem that we are faced with ... boost in performance, while the all-in-one model’s performance barely changes This fact can be explained by the fact that the entity type-only model is in itself errorful; measuring the performance...
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Báo cáo Y học: In vivo activation of plasma membrane H+-ATPase hydrolytic activity by complex lipid-bound unsaturated fatty acids in Ustilago maydis docx
... these two factors remain largely unchanged in the same conditions used in this study [18,21] This regulation by CLB-unsaturated fatty acids in U maydis differs from others described For example, ... plasma membrane H+-ATPase hydrolytic activity was mediated through changes in the fatty acid unsaturation of complex lipids Ó FEBS 2002 ´ 1008 A Hernandez et al (Eur J Biochem 269) Fig H+-ATPase ... altered the fatty acid profile, but that abnormal sterols per se were probably not directly responsible for the changes observed in H+-ATPase activity We tested the hypothesis that CLB-fatty acids...
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Báo cáo khoa học: Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1⁄TSC2 in C2C12 myotubes pptx
... influences mTOR signaling by regulation of the protein complex of tuberous sclerosis complex (TSC)1 ⁄ TSC2 [9–12] The TSC1 ⁄ TSC2 protein complex is a heterodimer composed of the TSC1 and TSC2 ... phosphorylated TSC2 protein (Fig 1C) The failure to detect a change in the stability of the TSC1 ⁄ TSC2 complex was not specific to muscle cells because complex formation between TSC1 and TSC2 ... observations suggest that the stability of the complex between TSC1 and TSC2 is not a critical factor in determining the function of the TSC1 ⁄ TSC2 protein complex in response to IGF-1 treatment To...
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Structural investigation of silicon nanowires using GIXD and GISAXS evidence of complex saw tooth faceting
... the six usual faces, all saw-tooth faceted Half of them (LF) present the large upward-facing facets and the other half (SF) present the small upward-facing facets The six additional faces truncating ... section The twelve faces are all sawtooth faceted and distributed in three families The (LF) family corresponds to large upward-oriented facets as indicated in Fig 6b and the (SF) family corresponds ... different types of facets oriented upwards (SF) type faces have small upward-facing facets while (LF) type faces have large upward-facing facets The edges of the hexagonal prism are truncated...
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Báo cáo khoa học: Probing the interface between factor Xa and tissue factor in the quaternary complex tissue factor–factor VIIa–factor Xa–tissue factor pathway inhibitor pptx
... recombinant tissue factor pathway inhibitor (TFPI) Evidence that the third Kunitz-type domain of TFPI is not essential for the inhibition of factor VIIa- tissue factor complexes on cell surfaces J Biol ... Morrissey, J.H & Johnson, A.E (1997) Tissue factor positions and maintains the factor VIIa active site far above the membrane surface even in the absence of the factor VIIa Gla domain A fluorescence ... recognition by the tissue factor–factor VIIa protease complex J Biol Chem 267, 6375–6381 Dittmar, S., Ruf, W & Edgington, T.S (1997) Influence of mutations in tissue factor on the fine specificity...
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focal press - building websites with html5 to work with mobile phones (2011)
... in your computer I will use a sample location to produce the map instead.”); fakeLatitude = 49.273677; fakeLongitude = -123.114420; mapServiceProvider(fakeLatitude,fakeLongitude); } } The next ... instance, a HEADER for Focal Press would look like the following ... Mobile€Phones The font-family definition allows you to select a font for your design Here is how you write the definition: font-family: Arial; The challenge you have in using the font-family definition...
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focal press html5, designing rich internet applications (2010)
... instance, a HEADER for Focal Press would look like the following ... thank my beloved family who put up with me disappearing for hours at a time to write my next great book I love you guys I could not have completed this project without you vii Preface Incredibly, ... into a new medium However, the Web has evolved Today, computers are blinding fast with many of us running SmartPhones faster than esktop d behemoths of just years ago Connection to the Web is...
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focal press rendering html5 illustration (2010)
... that allow you to complete complex, interactive SVG presentations Leveraging SVG Drawing Tools If you have gotten this far then you have realized that drawing with SVG is complex There are, unfortunately, ... Chrome and Safari rapidly adopting the standard through upport of the WebKit Web Browser project SVG as an s a lternative vector graphics technology is being widely adopted As an xample, Wikipedia.org ... square is drawn Figure 3.9 shows the final drawing You can create more complex shapes with the POLYLINE element In this example a set of stairs is created All you have to remember is that the...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu