... vitamin D levels and colorectal, breastand prostate cancerand colorectal adenoma 100 14 Randomised trials on vitamin D, cancerand mortality 113 15 Vitamin D, cancer prognostic ... 2.4 pmol/L d stands for deci; m stands for milli; stands for micro; n stands for nano; p stands for pico; and f stands for femto Abbreviations for measure of risk in epidemiological and clinical ... 25-hydroxyvitamin D, cancerand all-cause mortality 92 12.1 Prospective studies of serum 25-hydroxyvitamin D andcancerrisk 92 12.2 Studies of predicted serum 25-hydroxyvitamin D andcancer risk...
... Lacto-vegetarians (vegetarian diet which includes dairy products, but excludes eggs) are at greater risk of osteomalacia than ovolacto-vegetarians (vegetarian diet which includes dairy products and eggs) [6] ... belong to high risk groups A correct diagnosis can help avoid prolonged and needless investigations for these patients, as the condition is reversible and easily treated with vitamin D and calcium ... Hospital, Dublin, Ireland 2Department of Rheumatology, Connolly Memorial Hospital, Dublin, Ireland 3Department of Endocrinology and Diabetes Mellitus, Connolly Hospital, Dublin, Ireland Authors’ contributions...
... [7], osteoarthritis [8,9], and prostate cancer [10] The ESR1 gene has been linked with osteoarthritis [11], osteoporosis [12-16], breastcancer [17], and testicular cancer [18] Both genes are ... restriction fragment-length polymorphism and exon structure of the estrogen receptor gene in breastcancerand peripheral blood Cancer Res 1992, 52:77-83 Heimdal K, Andersen TI, Skrede M, FossA SD, Borresen ... Pera G, Haile RW, Coetzee GA: Association of prostate cancerrisk with genetic polymorphisms in vitamin D receptor and androgen receptor J Natl Cancer Inst 1997, 89:166-170 Ushiyama T, Ueyama H,...
... Adjusted for age, total energy intake and dietary intake of vegetables, vitamin B12, alcohol, salmon-type fish and shellfish e Adjusted for age, total energy intake and dietary intake of vegetables, ... acid and α-linolenic acid hAdjusted for age, total energy intake and dietary intake of vitamin B12, alcohol and dietary intake of other than omega-3 fatty acids ever, the mechanisms of action and ... phytoestrogens and testicular cancerrisk Nutr Cancer 2002, 44(1):44-51 Stattin P, Bylund A, Biessy C, Kaaks R, Hallmans G, Adlercreutz H: Prospective study of plasma enterolactone and prostate cancer risk...
... differentiation and cell cycle arrest in a number of malignant melanoma cells, including those in myeloid leukemia, and breast, prostate, colon, skin and brain cancer [4– 8] Phosphatase and tensin ... Krishnan AV (2000) Vitamin D and prostate cancer Endocrinology 141, 5–9 Holick MF (2004) Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease ... used for standardizing PTEN and Egr-1 mRNA Amplification primers were 5¢-ACCAGTGGCACTGTTGTTTCAC-3¢ and 5¢-TTCCTCTGGTCCTGGTATGAAG-3¢ for the PTEN gene [43], and 5¢-AGCCCTACGAGCACCTG-3¢ and 5¢-CGGTGGGTTGGTCATG-3¢...
... gene andrisk of lung cancer Med Sci Monit 2009, 15:BR232-BR242 111 Kilkkinen A, Knekt P, Heliovaara M, Rissanen H, Marniemi J, Hakulinen T, et al: Vitamin D status and the risk of lung cancer: ... correlated with the risk of colon cancer [109] For lung cancer, the picture is not clear at the present time While TaqI polymorphism of the VDR gene appears to be a risk factor for lung cancer Page of ... and mature osteoclasts, and it inhibits OPG expression, which binds RANKL and prevents RANK mediated osteoclastogenesis [37] VitD deficiency causes the development of an imbalanced calcium- and...
... ― Sources and types of vitamin D (pages & 3) ― What vitamin D does (page 3) ― Vitamin D and calcium (page 3) ― Cancerand vitamin D deficiency (pages & 5) Why are cancer patients at risk for vitamin ... supplement Cancerand Vitamin D Deficiency Vitamin D deficiency is extremely common in patients with all types of cancer Why are Cancer Patients at Risk for Vitamin D Deficiency? Cancer patients ... information to cancer patients and family member on the causes and current treatment of cancer that involves the bone • Provide information and serve as a resource for physicians, nurses, and other...
... contributed to study design and concept and writing and editing of the manuscript VT: contributed to the study design and concept, writing and editing of the manuscript and provided financial support ... K23AR054334 and #5T32DK007298 The authors responsibilities were as followed LJ, LVY and SEJ: contributed to the study design and concept, statistical analysis, and writing of the manuscript HMB, GM and ... (groups and 2) were characterized by sex, race, Acute Physiology and Chronic Health Evaluation II (APACHEII) and sequential organ failure assessment (SOFA) scores (for ICU patients) and whether...
... vehicle (A, D, G and J), calcipotriol (B, E, H and K) and Daivobet® (C, F, I and L) in Figure the psoriasis plaque assay Biomarker endpoints after treatment with vehicle (A, D, G and J), calcipotriol ... before (A, B and C) transplantation and after (D, E and F) transplantation and treatment in the psoriasis xenograft SCID mouse Before transplantation the expression of CD3 (A), CD4 (B) and CD8 (C) ... calcipotriol and BDP was well tolerated and no significant weight loss was observed Two hours after the last application, the animals were bled and sacrificed The serum levels of calcipotriol and BDP...
... significant association between weekly vitamin D dietary intakesand global cognitive function, and found that inadequate weekly vitamin D dietary intakes were associated with cognitive impairment ... in the study and takes responsibility for the integrity of the data and the accuracy of the data analyses Study concept and design: CA and OB Acquisition of data: CA and OB Analysis and interpretation ... supplementation andrisk of fractures N Engl J Med 2006, 354:669-683 Law M, Withers H, Morris J, Anderson F: Vitamin D supplementation and the prevention of fractures and falls: results of a randomized...
... VDR polymorphisms and susceptibility and outcome have been indicated in prostate, lung, and colon cancers [19-21] Zou et al [20] suggested that VDR polymorphisms of Cdx2, FokI, and BsmI were associated ... collected and classified using the LightTyper genotyping software, and genotypes were determined The absence or presence of the ApaI, BsmI, and FokI sites were designated as A, B, and F alleles and ... Bsm I, and Fok I VDR polymorphisms VDR, vitamin D receptor; SD, standard deviation Table Genotype and allele frequencies of Apa I, Bsm I, and Fok I VDR polymorphisms in subjects with and without...
... England, Holland, and France [10] Industrialized cod liver oil production (as the sole source of vitamin D food supply at that time) did not start before 1853 in Norway, Greenland, and Iceland ... influenza and vitamin D Epidemiology and Infection 2006, 134:1129-1140 Palm T: The geographical distribution and aetiology of rickets Practitioner 1890, 45:270-279 Stephen JM: Epidemiological and dietary ... In Norway and Denmark it has a subordinate place in the statistics of sickness relating to the earliest year of life Its principal seats are Germany, England, Holland, Belgium, France and Northern...
... metabolism, OA, the immune response, andcancer [12] The VDR gene acts as an important regulator of calcium metabolism and bone cell function [13], and it was the first candidate gene to be studied in ... elderly Dutch men and women It can be expected that the same polymorphisms could be important for both knee OA and hand OA, although no association between the VDR genotypes and hand OA was found ... with the risk of hand OA in Finnish middleaged women In addition, we evaluated whether the calcium intake modifies the relationship between the VDR gene polymorphisms and hand OA Materials and methods...
... the gel spots and western blotting experiment; MLL and JYL assisted with preparation for the serum samples and judgment for fibrotic stages; SCL and WMW were projective leaders and assisted with ... electrophoresis for proteomic expression analysis of a model breastcancer cell system Mol Cell Proteomics 2002, 1:91-98 36 Van den Bergh G, Clerens S, Vandesande F, Arckens L: Reversed-phase high-performance ... in F0-F2 stage (Fig 3A and Fig 3D) We used Bio-Plex Suspension Array System to measure the absolute protein concentration of A2M, VDBP and ApoAI according to protein standard curve We found that...
... was unaffected, and all four grandparents were of French-Canadian origin Family members were considered asthmatics if both a selfreported history of asthma and a history of physiciandiagnosed asthma ... the activation and inactivation vitamin D (CYP27A1, CYP27B1, CYP2R1 and CYP24A1) [31,32]; the vitamin D binding protein (GC) that binds to vitamin D and its plasma metabolites and transports ... associated with atopy (rs912505 and rs927650) were in modest LD (r2 = 0.36) and the two SNPs associated with asthma (rs2248359 and rs8124792) located in the promoter and the 3' region of the gene...
... 25-OH-D3 (Figure 3) Data handling and statistical analysis Clinical data and genotypes were all transferred to a SQL 2000 database and checked for completeness, paternity, and Hardy-Weinberg equilibrium ... the tested candidate genes are associated with both allergy and vitamin D metabolites Statistical significance, however, was weak, and varied even with different analysis strategies and software ... analysis and wrote the report J.A did the clinical survey, C.B did the SNP analysis, M.B built serum and DNA bank and did the vitamin D assays together with E.A who supervised also laboratory work and...
... RM: Vitamin D in overweight/obese women and its relationship with dietetic and anthropometric variables Obesity 2009, 17:778-782 McGill A-T, Stewart JM, Lithander FE, Strik CM, Poppitt SD: Relationships ... Poppitt SD: Relationships of low serum vitamin D3 with anthropometry and markers of the metabolic syndrome and diabetes in overweight and obesity Nutr J 2008, 7:4 Louie JK, Acosta M, Winter K, Jean ... viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice J Clin Invest 2008, 118:2771-2784 doi:10.1186/cc8894 Cite this article as: Krstić G: Th17 mediators and vitamin...
... Prostate – Breast – Colon – Heart – Gonads – Brain Bikle et al ASBMR Primer 2009 Vitamin D Deficiency and Adverse Health Outcomes • Epidemiological studies and RCT’s Hip fractures andrisk of falls ... PTH and FGF23? Hypocalcaemia ↑Calcium Calcium sensing receptor Parathyroid gland (PTH) PTH/PTHrP receptor (Kidney) 24,25(OH)2D3 CYP24 25OHD CYP27B1 1,25(OH)2D3 Bone and Gut FGF23 Calcium and ... Africa/M.East Algeria Denmark Finland France Netherlands Norway Spain Sweden U.K Australia Bangladesh China India Israel Japan Kuwait Lebanon Mongolia New Zealand Vietnam Ethiopia Kenya Nigeria...