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injury to the spinal cord

TARGETING ACUTE PHOSPHATASE PTEN INHIBITION AND INVESTIGATION OF A NOVEL COMBINATION TREATMENT WITH SCHWANN CELL TRANSPLANTATION TO PROMOTE SPINAL CORD INJURY REPAIR IN RATS

TARGETING ACUTE PHOSPHATASE PTEN INHIBITION AND INVESTIGATION OF A NOVEL COMBINATION TREATMENT WITH SCHWANN CELL TRANSPLANTATION TO PROMOTE SPINAL CORD INJURY REPAIR IN RATS

Y khoa - Dược

... contribute to the inflammatory response in the injury area Furthermore, extensive release and cellular reactivity to a variety of inflammatory-related cytokines and chemokines contribute to progressive ... transplantation This therapy has been investigated extensively due to the benefits these cells promote once engrafted into the injured spinal cord Named after German anatomist, Theodore Schwann (1810-1882), ... implantation of the cells avoids not only the cytotoxic environment of the acute injury epicenter, but also allows for the development of cystic cavities in which to inject the cells into Even still,...
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Báo cáo y học:

Báo cáo y học: "Foramen Magnum Arachnoid Cyst Induces Compression of the Spinal Cord and Syringomyelia: Case Report and Literature Review"

Y học thưởng thức

... cervical spinal cord appeared notch-like due to the compression of the cyst The spinal cord was thickened from the pons to the thoracic spinal cord T10, and a syrinx was seen in the spinal cord with ... herniates into the foramen magnum and spinal canal to compress the spinal cord, consequently causing blockage of the spinal canal and the stoppage of cerebral spinal flow, leading to syringomyelia ... tightly adhered to the cerebrum, pons and cervical spinal cord The compartments were then separated and the posterior wall of the cyst was excised to break down the cystic structure The tissue was...
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báo cáo hóa học:

báo cáo hóa học:" Subacromial impingement in patients with whiplash injury to the cervical spine" docx

Hóa học - Dầu khí

... secondary to a hyper flexion/extension injury caused by their recent accident Those with neck or shoulder symptoms prior to the index injury were excluded from the study 202/220 of the patients ... pain following the injury, of these 11/220 (5%) had signs and symptoms consistent with subacromial impingement (Table 1) In the other 45 patients the symptoms were radiation from the neck and no ... primary care sector, by a physiotherapist who was delivering the 'neck' therapy The remainder had their diagnosis made at the time of our report and subsequently advised to seek further medial assessment...
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báo cáo hóa học:

báo cáo hóa học:" The value of SPECT in the detection of stress injury to the pars interarticularis in patients with low back pain" doc

Hóa học - Dầu khí

... sequence) through the area of abnormality on SPECT, is recommended to confirm the diagnosis and stage the lesion If SPECT is negative, pars stress is unlikely to be the cause of the low back pain ... predict the probability of ultimate bone healing [22,23] However, CT of the spine results in higher ionizing radiation exposure compared to bone scintigraphy [24] Furthermore, there are reports in the ... the vertebral body with extension to the pedicle [35,36] Ultimately, SPECT may be fused with CT, if needed, to help add specificity to the findings Conclusions The economic burden of back pain...
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Báo cáo khoa học:

Báo cáo khoa học: "Immunohistochemical Localization of Bcl-2 in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis" docx

Báo cáo khoa học

... inflammatory cells not undergo apoptosis in perivascular lesions suggests that in these cells, during the peak stage of EAE, anti-apoptotic Bcl-2 predominates, rather than the cytotoxic effectors ... Immunohistochemical Localization of Bcl-2 in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis 281 Table Bcl-2 immunoreactivity in cell phenotypes of the spinal cords of ... the apoptosis of inflammatory cells in EAE parenchyma cells lacking anti-apoptotic Bcl-2 requires additional molecules from the apoptosis cascade In this study, in EAE spinal cords, the TUNEL...
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Báo cáo khoa học:

Báo cáo khoa học: "Embryonic Intermediate Filaments, Nestin and Vimentin, Expression in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis" pdf

Báo cáo khoa học

... during the peak and recovery stages of EAE, respectively Experimental rats (n = 5) in each group were sacrificed under ether anesthesia, and the spinal cords were removed Portions of each spinal cord ... Nestin and Vimentin, Expression in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis 11 Fig Immunohistochemical staining of nestin in the spinal cords of normal rats (A) and ... CFA At the peak stage of EAE (day 14 PI), a large number of inflammatory cells infiltrated the perivascular lesions and parenchyma of spinal cords in rats with EAE Thereafter, inflammatory cells...
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Báo cáo khoa học:

Báo cáo khoa học: "Increased expression of osteopontin in the spinal cords of Lewis rats with experimental autoimmune neuritis" doc

Báo cáo khoa học

... EAN-affected spinal cords may facilitate the migration of inflammatory cells, including both Th1 and Th2 cells, into the spinal cord parenchyma if needed The population of inflammatory cells in the subarachnoid ... Osteopontin in rat spinal cord with EAN nerves and spinal roots These two molecules may be involved in cell migration into the spinal cord in the early stages of EAN Further study of the functional ... (Vector, USA) Before mounting, the sections were counterstained with hematoxylin Fig Histology of spinal cords of normal (A) and EAN affected (B) rats A There were no inflammatory cells in the spinal...
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Báo cáo khoa học:

Báo cáo khoa học: "Increased phosphorylation of caveolin-1 in the spinal cord of irradiated rats" pdf

Báo cáo khoa học

... vascular endothelial, glial, and ependymal cells in the spinal cords of the normal rats (Figs 2A & B) In the irradiated spinal cords, p-caveolin-1 was found to be intensely immunostained in the ramified ... Korea) The rats from the other group were not irradiated and used as controls (n = 7) Tissue sampling The rats were sacrificed at 24 h post-irradiation (PI) under ether anesthesia The spinal cords ... the first study demonstrating an increase in the level of caveolin-1 phosphorylation in irradiated rats located primarily in the microglial and vascular endothelial cells of the spinal cord The...
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Báo cáo y học:

Báo cáo y học: "Intraperitoneal Alpha-Lipoic Acid to prevent neural damage after crush injury to the rat sciatic nerve" docx

Báo cáo khoa học

... protein) levels in all groups The pathophysiology of the crush injury has not been fully understood, and it has been debated whether the ischemia, secondary to compression, or the mechanical deformation ... nerve and these effects were similar at the first hour and on the 3rd day LPO level in the tissue samples was expressed as MDA It was measured according to procedure of Ohkawa et al [11] The reaction ... after injection of NMDA into the striatum [7] However, to our knowledge, the effects of aLA on crush injury have not been investigated in the English literature [3-7] The increased formation of...
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Báo cáo y học:

Báo cáo y học: "Bullet embolization to the external iliac artery after gunshot injury to the abdominal aorta: a case report" ppsx

Báo cáo khoa học

... missed the first time In the case of the possibility of the obstruction occurring between the operations, there are two scenarios to consider First, the migration of the projectile due to the movement ... enter the left side of the aortic arch or the abdominal aorta may be expected to be found in a lower extremity Those that enter the arterial system through the left side of the heart or the right ... which is 45° from the midline Embolisms to the lower extremities are therefore three times more frequent on the left side than on the right side The importance of prompt removal of the peripherally...
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Báo cáo y học:

Báo cáo y học: "Thread embedded into penile tissue over time as an unusual hair thread tourniquet injury to the penis: a case report" doc

Báo cáo khoa học

... Figure the ring1scar on the penis Thedorsolateral aspects and the exuberant granulation on The ring scar on the penis and the exuberant granulation on the dorsolateral aspects The skin distal to the ... there was a tourniquet on his penis The mechanism of injury in hair thread tourniquet is ischemia in the parts distal to the site of tourniquet appli- Figure placed on a piece of gauze swab The ... along the site of the tourniquet The ultimate location of the hair thread was immediately subcutaneous, as if the tourniquet had 'sunk in' through the skin, embedded in fibrous tissue, with the...
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báo cáo khoa học:

báo cáo khoa học:" Efficacy of low level laser therapy on neurosensory recovery after injury to the inferior alveolar nerve" ppt

Báo cáo khoa học

... subject to evaluate his or her own attractiveness by comparing it to the standard photographs of the AC of the IOTN Two examiners were involved in the study, one for the DHC and the other for the ... openbite in their perception of their malocclusion Also, there is no evidence of how the severity of those traits is perceived by people These shortcomings of the IOTN indicate the need to study the ... attributed to the nature of the IOTN itself The scores of the DHC may have been exaggerated by the rank of displacement, which would give a high score in otherwise normal occlusion In addition, the...
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báo cáo khoa học:

báo cáo khoa học:" Efficacy of low level laser therapy on neurosensory recovery after injury to the inferior alveolar nerve" ppsx

Báo cáo khoa học

... had hypoesthesia on the area of the chin, gingiva, buccal regions and the lips, and patient III had complete paresthesia caused by the injury of the IAN Besides these impairments, the clinical ... between the right mandibular third molar tooth and the IAN before surgery (Figure 1) It was thought that these impairments had formed due to either the third molar surgery or the local anesthetic ... following the protocol of Khullar et al [11] The LLL treatments and recording of data were performed by a second doctor not involved in any of the surgeries, and the analysis of the recorded data...
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Báo cáo y học:

Báo cáo y học: " Mathematical model of blunt injury to the vascular wall via formation of rouleaux and changes in local hemodynamic and rheological factors. Implications for the mechanism of traumatic myocardial infarction" pot

Báo cáo khoa học

... is the volume fraction of the second phase), not only the shape and size of the erythrocytes but also the irregular arrangement of the particles and their collisions with each other and with the ... particle to accelerate In addition to gravity, the particle is affected by the frictional force, which acts in the opposite direction and has a value directly proportional to the velocity according to ... that the main source of rouleaux is the erythrocytes themselves The higher the erythrocyte concentration, the more rouleaux remain in the blood despite an increase in the forces that destroy them...
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Báo cáo hóa học:

Báo cáo hóa học: " Quantification of the effects of an alpha-2 adrenergic agonist on reflex properties in spinal cord injury using a system identification technique" pptx

Hóa học - Dầu khí

... chair with the ankle strapped to the footrest and the thigh and trunk strapped to the chair The seat and footrest were adjusted to align the ankle axis of rotation with the axis of the force sensor ... was determined with the subject's ankle attached to the motor The ankle range of motion was recorded using the goniometer built onto the motor, but under passive conditions, to guarantee safety ... and torque The IRF characterizes the behavior of the system over its entire range of frequencies The intrinsic IRF was convolved with the experimental input to predict the intrinsic torque The...
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Báo cáo hóa học:

Báo cáo hóa học: " Kinematic analysis of the daily activity of drinking from a glass in a population with cervical spinal cord injury" potx

Hóa học - Dầu khí

... for the glass from the starting position and grasping it, raising the glass to the mouth, drinking, lowering the glass to the pickup point, and returning the hand to the starting position All the ... contralateral to the study side of the subject The other camera positioned laterally (Figure 1) The system was calibrated by placing three active markers on the floor to serve as the laboratory reference ... goals appropriate to the severity of the injury Consequently, the objectives of the present study were: To compare the data obtained from kinematic analysis of the upper limb during the drinking task...
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báo cáo hóa học:

báo cáo hóa học: " The effects of powered ankle-foot orthoses on joint kinematics and muscle activation during walking in individuals with incomplete spinal cord injury" pptx

Hóa học - Dầu khí

... learned to use the pushbuttons to control the timing and amplitude of the orthoses assistance The three other subjects practiced but were unable to learn the appropriate timing of the pushbuttons ... assistance These large, stationary devices make the job of the therapist easier but they may encourage passivity by the patient during locomotor training Another drawback to these devices is that they ... pushbuttons activated either by a therapist or by the patient The pushbuttons generate a real-time voltage proportional to the amount of button press A computer interface converts this voltage to...
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Báo cáo y học:

Báo cáo y học: "Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury" ppt

Báo cáo khoa học

... of apoptotic cells in the injured spinal cord compared to those found in the injured spinal cord without any treatment (Figure 2B) Extensive inflammation in the injured spinal cord in the subacute ... until the tracking dye reached the bottom of the gel The gel was subjected to silver staining according to the method described by Tsai et al [21] Quantitative analysis of the proteins in the 2-DE ... of proteins in the injured epicenter at the subacute stage of SCI remain to be elucidated Since a contusive injury to the spinal cord is most similar to crush and fracture spinal cord injuries...
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