... E(RS ) ¡ Á2 (1 ¡ ») ¡ Á2 (1 + a + b)´; (1.2) where Rj is the rateof return of asset j, RS is the rateof return of the market portfolio and is de…ned as RS ´ ¯j ´ cov(Rj ;RS ) var(RS ) , P1 P1 +P2 ... securities) of IPOs IPO residual risk acts as a source of systematic risk and is priced in equilibrium From the point of view that innovation is the source of sustained economic growth and economic ... is de…ned as the negative of the ratio of the total number of shares available for short sale over the total number of shares outstanding IPO shares available Mauer and Senbet (1992) provide...
... cS1 and cA are S1 and actin concentrations, respectively Reverse rates of the reactions k)1, k)2, a)T, and a)B were assumed from Chen et al [37], and forward rates were calculated from K1, KB and ... concentration of i (lm); and Fmax and Fmin are the maximum and minimum values of intensity, respectively Modeling experimental results Light scattering was used to measure the binding of S1 ADP to actin and ... and p2 are fractions of actin units in the inactive and active states, respectively; hI and h2 are fractions of actin containing bound S1 in the inactive and active states, respectively; K1 and...
... are examined by Liu and Pan (2003), Liu, Longstaff, and Pan (2003) and Das and Uppal (2001) Dufresne and Hugonnier (2001) study the impact of event risk on pricing and hedging of contingent claims ... include Gilboa and Schmeidler (1989), Epstein and Wang (1994), Anderson, Hansen, and Sargent (2000), Chen and Epstein (2002), Hansen and Sargent (2001), Epstein and Miao (2003), Routledge and Zin (2002), ... types of random shocks One is a standard diffusive component, and the other is pure jump, capturing rare events with low frequency and sudden occurrence While the probability laws of both types of...
... (0.6 and 2.4 lM, 100 lL) equilibrated in buffer and M GdnHCl was loaded onto the column pre-equilibrated with 50 mM Tris/HCl buffer containing the same concentration of GdnHCl, pH 7.5 Calibrated ... activity of d2-crystallin was monitored as a function of the appearance of fumarate at 240 nm Tryptophan fluorescence was measured by the emission spectra at an excitation wavelength of 295 nm ... ðVe À V0 Þ=ðVt À V0 Þ where, Ve is the elution volume of the protein elution peak and Vt and V0 are the total volume and the void volume of the column, respectively Analytical ultracentrifugation...
... number of mutations per gene The implication of this observation is that the effects of most mutations are small compared with those of G270V, E406G, and R166G Changes at the surface of the protein ... 50 lgÆmL)1 kanamycin and increasing concentrations of TMP for the three rounds of evolution For the first round, lgÆmL)1 TMP was used, and in the second and third rounds, 10 and 20 lgÆmL)1 TMP were ... Kinetic and crystallographic analysis of mutant Escherichia coli aminopeptidase P: C-terminal domain of E coli aminopeptidase P insights into substrate recognition and the mechanism of catalysis...
... (a) the role of the N-terminal extension; (b) the role of the D to N mutation; and (c) the role of the sequence and length of the C-terminal extension To address whether presence of extra residues ... conditions (see Materialsand methods) The cell pellets were sonicated and the resulting lysates were loaded onto pre-equilibrated amylose columns Sufficient and equivalent amounts of amylose resin ... issue that solubility of fusion proteins is not necessarily indicative of either proper folding or of increased solubility of the protein of interest We propose that the success of fusion protein...
... element of EP Θ and the set of fixed points of nonexpansive mappings Furthermore,Yao et al 8, 10 introduced an iterative scheme for finding a common element of EP Θ and the set of fixed points of finitely ... element of the set of solutions of an equilibrium problem and the set of common fixed point of infinitely many nonexpansive mappings in H Let {Tn }∞ be a sequence of n nonexpansive mappings of C into ... suggest and analyze an iterative scheme for finding a common element of the set of fixed point of infinitely nonexpansive mappings, the set of solutions of an equilibrium problem and the set of solutions...
... region one can see the regions of stability of the point of equilibrium x1 that were obtained by condition 3.3 grey and green regions and by conditions 3.4 , 3.5 cyan and green regions Stability ... dynamics of xn Journal of Difference Equations and Applications, vol 9, no 8, pp 731–738, 2003 E Camouzis and G Papaschinopoulos, “Global asymptotic behavior of positive solutions on the system of rational ... clear that the stability of the trivial solution of 2.2 is equivalent to the stability of the equilibrium point of 2.1 Together with nonlinear equation 2.2 we will consider and its linear part k...
... aspects of the laboratory work, analyzed the data and prepared the manuscript SK, SA, MW and CB participated in the collection of clinical data and the recruitment of patients into the study UW and ... the patient and the control cohort and all analyzed subgroups The distribution of genotypes and the resulting allele frequencies of the variant PTPN22 1858T allele in RA patients and healthy ... in RA patients The CT and TT genotype was present in 37.9% of patients and 19.2% of healthy controls, resulting in an OR of 2.57 (95% CI 1.85–3.58, p < 0.001) Carriage of a homozygous TT genotype...
... set of sequences and the thermodynamics and specificity of binding (see Materialsand methods for a fuller discussion) [9] A variation on this idea treats the PWM as a predictor of affinity and ... (see Materialsand methods) and have used this model to study the interaction of yeast transcription factors Ndt80p and Sum1p Ndt80p is an activator of genes expressed during the middle stage of ... positiondependent models that define the size and shape of regulatory regions and describe the nature of cooperative and competitive interactions (see Materialsand methods) These functions can be as...
... the development of the present work The molar distribution of CO/CO2 and CO/H2 as a function of the temperature of the synthesis gas produced by the gasification of woody biomass materials in downdraft ... Determination of the enthalpy of formation of feedstock is the second step, and knowledge of the HHV or LHV (low heating value) of the feedstock is necessary Applying the HHV definition the enthalpy of formation ... (2014) 189e201 presented here: 52.28% of C, 6.61% of H, 41.05% of O, 0.1% of N, 0.01% of S, 1.54% of Ash In work by Leoneti et al [60] it is stated that one of the possible applications for the...
... requirements of the VUV photolysis of water according to Eq (1) are related to the formation of high local concentration of hydroxyl radicals (OH.) and a series of other species (Gonzalez and Braun, ... both generated from the excitement of H2O and oxygen molecules The pseudo-first order reaction rate constants of the three driving forces are referred to kuv.only, k OH·H2O, and kOH·O2 and also ... those in the VUV/N2 and VUV/O2 systems because of OH generated from the photolysis of H2O and O2 are almost scavenged by the adding t-butanol In addition, the decomposition rates of Red 141 conducted...
... energy of a pair of molecules of types i andj a:, Mole fraction of ith species in vapour phase %+,%- Charges of positive and negative ions respectively in units of the proton charge « Coefficient of ... surface of the catalyst It is therefore a problem of rates and not of equilibria The theory of equilibria, based on thermodynamics, is much simpler, and also more precise, than any theory of rates ... differential of a function of state and its integral is Us- UA• which depends only on the initial and final states A and B; dq and dw, on the other hand, are not the differentials of a function of state,...
... the caprice of one man, a foreigner by race and by education, andof a set of military ruffians andof infamous civilians, fit only to have formed the staff and the privy council of Catiline ... conversation; every individual stands defenceless and insulated, in the face of this unscrupulous executive, with its thousands of armed hands and its thousands of watching eyes The only opposition ... hope of undisturbed peace and progressive civilisation and prosperity An alliance with England was one of the favourite dreams of the first Napoleon He believed, and with reason, that England and...
... HPO, the oxidized form of HP These measured rate constants are reliable and accurate, because of (a) the high quality of the stopped-flow data as illustrated in Figs andand (b) the consistency ... the measurements of both equilibrium and kinetic constants of the physical steps by equilibrium and stopped-flow fluorimetric analysis and the determination of the rate constants of the chemical ... inhibitors NP and MP To assess the differences in the rate constants of the reduced and oxidized pterins, we also measured the association and dissociation rate constants of HPO and compared them...
... g ao sn e sn of GM food with conventional and quality-enhanced products, mandates the labelling and traceability of GM products, and allows only a stringent adventitious presence of GM content ... the introduction of GM products, and endogenise the price of land and the reward to the additional efforts supplied by farmers The model is calibrated to replicate observed data of EU agriculture, ... the effects of IP (of the superior products) and the impact of labelling and traceability requirements (on the inferior product).6 The model Based on the foregoing, the demand, supply and equilibrium...
... Average of Japan’s Mega Banks 1,750 Number of Municipalities*2 26,146 25,786 JAPAN POST BANK Total of Six Major City Banks NUMBER OF DOMESTIC OUTLETS*1 NUMBER OF DOMESTIC CD ATMS (As of March ... buildings that are separate from post office facilities At post of- • ATM service fices, which are operated by JAPAN POST NETWORK, employees handle bank agency operations as one facet of counter operations ... including branches, ATMs, and • Broad base of customers • Steady, conservative investment • Maintenance of low-cost extending to all generations operations and all regions of Japan the Internet...
... adoption of outdoor relief policies in the 1770s and 1780s and for the significant differences in the administration of relief between the southeast of England and the west and north, and it analyzes ... increase in labor demand for hedging and ditching, and a long-run increase in labor demand by the cultivation of commons and waste, and the adoption of new cropping systems that often followed However, ... out-migration rates in England from 1816 to 1831 were similar to out-migration rates in developing countries during the 1960s and 1970s Further evidence of labor mobility, andof the importance of London...
... standard procedure of s-MDH assay, monitoring the rateof the fall of absorbance of 0.2 mM NADH at 340 nm at 25 °C in 150 mM sodium phosphate buffer (pH 7.6) containing 0.5 mM oxaloacetate and ... expands and remains more Fig Equilibrium ‘dissociation and unfolding’, and ‘association and refolding’ of s-MDH, as measured by size-exclusion HPLC Experimental conditions were as described in Materials ... characterization of the intermediates to understand the structural changes involved in each transition, and (b) analysis of the kinetic mechanism that enables determination of the rate constants of individual...