infections in kidney transplant recipients
Tuberculosis in Liver Transplant Recipients: A Systematic Review and Meta-Analysis of Individual Patient Data doc
Ngày tải lên :
29/03/2014, 03:20
... regimens including pyrazin-
amide, 31% received drug regimens including a fluoro-
quinolone, and 17% received drug regimens including
streptomycin. Induction drug regimens consisted of 2
drugs in 5% ... MTB infection was defined as including
lung or mediastinal lymph node involvement. We de-
fined multiorgan (ie, miliary) MTB infection as involve-
ment of 2 or more organs (lymph nodes draining in-
fected ... positive tubercu-
lin skin test (TST) result in the absence of symptoms or
clinical findings suggestive of active infection. In ana-
lyzing LTBI treatment, we included studies reporting 10
or more...
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báo cáo hóa học: " Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL" pot
Ngày tải lên :
18/06/2014, 19:20
... most clinically relevant items, rel-
ative to response rate, inter-item correlation, and floor or
ceiling effects. The items were eliminated in cases of miss-
ing values exceeding 5%, high inter-item ... score
within every dimension. A missing scale score was substi-
tuted if over half of the items in each scale were missing.
All dimensions were linearly transformed to a 0–100
scale, with 100 indicating ... determinant of quality
of life than it is specific to kidney transplantation. The
RTQ can be utilized alone or in complement with the
SF36, according to the clinician's objective. The interest...
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Chapter 126. Infections in Transplant Recipients (Part 1) pdf
Ngày tải lên :
07/07/2014, 15:20
... Medicine > Chapter 126. Infections in Transplant
Recipients
Infections in Transplant Recipients: Introduction
The evaluation of infections in transplant recipients involves consideration
of ... corneal transplants.
e
T. gondii
usually causes disease in the brain. In hematopoietic stem cell
Chapter 126. Infections in
Transplant Recipients
(Part 1)
Harrison's Internal Medicine ... recipient of the transplanted organ. Infections following
transplantation are complicated by the use of drugs that are necessary to enhance
the likelihood of survival of the transplanted organ...
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Chapter 126. Infections in Transplant Recipients (Part 2) potx
Ngày tải lên :
07/07/2014, 15:20
... 126. Infections in
Transplant Recipients
(Part 2)
In many transplantation centers, transmission of infections that may be
latent or clinically inapparent in the donor organ has resulted in ...
latent infections already. Nevertheless, most infections occur in a predictable time
frame after transplantation (Table 126-2).
Table 126-
2 Common Sources of Infections after Hematopoietic ... and
Trypanosoma cruzi (the latter particularly in Latin America). Clinicians caring for
prospective organ donors should also consider assessing stool for parasites, should
...
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Chapter 126. Infections in Transplant Recipients (Part 4) ppsx
Ngày tải lên :
07/07/2014, 15:20
...
becomes available. Promising new drugs that are now being assessed in clinical
trials include maribavir, a benzimidazole ribonucleoside that inhibits a viral
protein kinase activity (UL97).
... ulcerations occur in both the lower and the upper
gastrointestinal tract, and it may be difficult to distinguish diarrhea due to GVHD
from that due to CMV infection. The finding of CMV in the liver ...
abnormalities. It is interesting that the ocular and neurologic manifestations of
CMV infections are uncommon in these patients.
Management of CMV disease in HSCT recipients includes strategies...
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Chapter 126. Infections in Transplant Recipients (Part 5) potx
Ngày tải lên :
07/07/2014, 15:20
... disease.
Treatment of CMV pneumonia in HSCT recipients (unlike that in other
clinical settings) involves both IV immune globulin (IVIg) and ganciclovir. In
patients who cannot tolerate ganciclovir, ... Chapter 126. Infections in
Transplant Recipients
(Part 5)
Like prophylaxis, preemptive treatment, which targets patients with
polymerase chain reaction (PCR) evidence of ...
antibodies to T cells). Although less likely in autologous transplantation,
reactivation can occur in T cell–depleted autologous recipients (e.g., patients being
given antibodies to T cells for the...
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Chapter 126. Infections in Transplant Recipients (Part 6) ppsx
Ngày tải lên :
07/07/2014, 15:20
... the
Chapter 126. Infections in
Transplant Recipients
(Part 6)
PCR can be used to monitor EBV production after hematopoietic stem cell
transplantation. High or increasing viral loads predict ... critical in an assessment of
posttransplantation infections.
to have activity against the different forms of latent EBV infection. Preventing
lytic replication in these patients would theoretically ... resulted in disease in HSCT recipients, although
some cases of virus-associated marrow aplasia have been reported in the
peritransplantation period. The relatively low seroprevalence of KSHV in the...
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Chapter 126. Infections in Transplant Recipients (Part 7) docx
Ngày tải lên :
07/07/2014, 15:20
... therapy (when indicated), and rapid diagnosis and
treatment of infections can be lifesaving in SOT recipients, who, unlike most
HSCT recipients, continue to be immunosuppressed.
SOT recipients ... acute infections in recipients of
SOT are different from those that infect HSCT recipients because SOT recipients
do not go through a period of neutropenia. As the transplantation procedure
involves ... (Chap. 177). Intranasal pleconaril, a capsid-binding
agent, is being studied for the treatment of enterovirus infection.
Rhinoviruses and coronaviruses are frequent co-pathogens in HSCT
recipients; ...
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Chapter 126. Infections in Transplant Recipients (Part 8) potx
Ngày tải lên :
07/07/2014, 15:20
... 126. Infections in
Transplant Recipients
(Part 8)
Kidney Transplantation
(See Table 126-4)
Table 126-4 Common Infections after Kidney Transplantation
Period after Transplantation
Infection ... of Infections in Transplant Recipients
Risk
Factor
Organism Prophylactic
Antibiotics
Examination(s)
a
Travel
to or
residence in
area with
known risk of
fungal
infection
Coccidioides, ... chest
imaging and/or no
previous treatment
Chest imaging;
PPD and/or cell-
based
assay
a
Serologic examination, PPD testing, and interferon assays may be less
reliable after transplantation....
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Chapter 126. Infections in Transplant Recipients (Part 9) pot
Ngày tải lên :
07/07/2014, 15:20
... Chapter 126. Infections in
Transplant Recipients
(Part 9)
Middle-Period Infections
Because of continuing immunosuppression, kidney transplant recipients are
predisposed to lung infections ... JC virus (polyomavirus hominis types 1
and 2) have been cultured from the urine of kidney transplant recipients (as they
have from that of HSCT recipients) in the setting of profound immunosuppression. ...
ulcerating lesions in the anogenital area may lead to bladder and rectal dysfunction
as well as predisposing to bacterial infection. VZV may cause fatal disseminated
infection in nonimmune kidney...
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Chapter 126. Infections in Transplant Recipients (Part 10) pdf
Ngày tải lên :
07/07/2014, 15:20
... 126. Infections in
Transplant Recipients
(Part 10)
Kidney transplant recipients are also subject to infections with other
intracellular organisms. These patients may develop pulmonary infections ... cause pulmonary
infiltrates or disseminated disease.
Late Infections
Late infections (>6 months after kidney transplantation) may involve the
CNS and include CMV retinitis as well as ... less common than
in other transplant settings, usually developing in the first few months after kidney
transplantation. Again, TMP-SMX is helpful in prevention. In endemic areas,
histoplasmosis,...
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Chapter 126. Infections in Transplant Recipients (Part 11) pptx
Ngày tải lên :
07/07/2014, 15:20
... lung transplant recipients with symptomatic CMV disease have pneumonia.
Difficulty in distinguishing the radiographic picture of CMV infection from other
Chapter 126. Infections in
Transplant ... Cryptococcus.
Mediastinitis may occur at an even higher rate among lung transplant
recipients than among heart transplant recipients and most commonly develops
within 2 weeks of surgery. In the absence ... against CMV
and is also active against HSV. The prophylaxis of CMV infection with IV
ganciclovir—or increasingly with valganciclovir, the oral alternative—is
recommended for lung transplant recipients. ...
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