indulging your creativity and saving money

Multi criteria analysis in environmental management: Selecting the best stormwater erosion and sediment control measure in Malaysian construction sites

Multi criteria analysis in environmental management: Selecting the best stormwater erosion and sediment control measure in Malaysian construction sites

Ngày tải lên : 05/09/2013, 16:11
... input, easiness to understand and use, and so forth The most essential factors for choosing the MCA technique is the easiness of understanding by the analyst, the stakeholders and use Ref [16] stated ... water quality improvements and enhancement of amenity/ecological provision Thus, design and construction, environmental/ecological impact, operation and maintenance, health and safety, social/urban ... expert’s opinions Based on these interviews and consultations, technical and environmental criteria were assigned with a weighed factor of and the economic and social criteria were assigned with a...
  • 10
  • 466
  • 0
Lab 7.2.4 Selecting the Root Bridge

Lab 7.2.4 Selecting the Root Bridge

Ngày tải lên : 05/11/2013, 12:15
... steps are complete, log off by typing exit, and turn all the devices off Then remove and store the cables and adapter 4-6 CCNA 3: Switching Basics and Intermediate Routing v 3.0 - Lab 7.2.4 Copyright ... clearing out previous configurations and starting with an unconfigured switch Instructions are provided for the 2900, 2950, and 1900 Series switches 2900 and 2950 Series Switches Enter into the ... 2, go to Step and restart the switch using the reload command Software restart (using the reload command) 5-6 CCNA 3: Switching Basics and Intermediate Routing v 3.0 - Lab 7.2.4 Copyright  2003,...
  • 6
  • 396
  • 0
Selecting the right manufacturing improvement tools, elsevier (2007)

Selecting the right manufacturing improvement tools, elsevier (2007)

Ngày tải lên : 04/12/2013, 23:54
... Bottom-up ownership and employee engagement Education and training Action plans and measures Visual communication Standards and procedures Benchmarking and aggressive goals Audits and assessments ... better than yours and learning from them, adapting and improving your own process " Benchmarking, then, involves emulating the processes and practices of the other companies to improve yours so ... plants Process plants on the other hand tend to be benefit more from RCM, PdM, and maintenance planning and scheduling and less from lean principles and tools, and they typically have an operator...
  • 395
  • 330
  • 0
Tài liệu Lab 7.2.4 Selecting the Root Bridge docx

Tài liệu Lab 7.2.4 Selecting the Root Bridge docx

Ngày tải lên : 11/12/2013, 14:15
... steps are complete, logoff, by typing exit, and turn all the devices off Then remove and store the cables and adapter 4-5 CCNA 3: Switching Basics and Intermediate Routing v 3.0 - Lab 7.2.4 Copyright ... host to use the same subnet for the address, mask, and default gateway as on the switch Step Verify connectivity a To verify that the hosts and switches are correctly configured, ping the switches ... _ _ Step Look at the VLAN interface information a On Switch_A, type the command show interface VLAN1 at the privileged exec mode prompt as follows: Switch_A#show interface...
  • 5
  • 364
  • 0
Tài liệu Selecting the Top n Rows in a DataTable doc

Tài liệu Selecting the Top n Rows in a DataTable doc

Ngày tải lên : 14/12/2013, 18:16
... DataTable(ORDERS_TABLE); da.Fill(dt); da.FillSchema(dt, SchemaType.Source); // Get the default view for the table and bind it to the grid dv = dt.DefaultView; dataGrid.DataSource = dv; } private void selectButton_Click(object ... dv[topN-1][topNFieldName]); // Apply the filter to the view dv.RowFilter = rowFilter.ToString( ); // Handle where there is more than one record with the nth value // Eliminate enough rows from the bottom ... dv.Count; i > topN; i ) { // Exclude the record using a filter on the primary key rowFilter.Append(" AND " + ORDERID_FIELD + "" + dv[i-1][ORDERID_FIELD]); refilter = true; } // Reapply the view filter...
  • 4
  • 332
  • 0
Tài liệu Báo cáo khoa học: Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft doc

Tài liệu Báo cáo khoa học: Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft doc

Ngày tải lên : 18/02/2014, 04:20
... by the disulfide bond between C108 and C119 Its attachment to the body of the enzyme is stabilized by two salt bridges, between H110 and D22, and between R116 and D224 The crystal structure suggested ... loop displacement in the unliganded and liganded structures The occluding loop (red) is shown in on the surface of the papain-like part of the structure (gray) (A) Unliganded cathepsin B (PDB code: ... active site cleft It was shown that the single and double mutations D22A, H110A, R116A and D224A disrupted the salt bridges between the occluding loop and the body of the enzyme, resulting in enhanced...
  • 8
  • 632
  • 0
Tài liệu Báo cáo khoa học: Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins docx

Tài liệu Báo cáo khoa học: Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins docx

Ngày tải lên : 18/02/2014, 08:20
... acid and a base on each side of the hydrolyzed bond [16] E96 and H137 in a-sarcin and E58 and H92 in RNase T1 act as the base and acid groups, respectively Comparing the 3D structures, E66 and ... N56–D58) and seven b-strands (b1, I3– C6; b2, F17–D20; b3, H42–Y44; b4, L64–P68; b5, R95– 2384 A99; b6, G109–H113; b7: F126–K128) The b-strands form an N-terminal hairpin (b1 and b2) and an antiparallel ... A Fig 1Ha and 1HN conformational shifts (dobserved–drandom coil) in ppm for HtA at pH 4.1 and 298 K The amino acid sequence and the elements of secondary structure are shown; b-strands are represented...
  • 10
  • 607
  • 0
Tài liệu Báo cáo khoa học: Modulation of the enzymatic efficiency of ferredoxin-NADP(H) reductase by the amino acid volume around the catalytic site pptx

Tài liệu Báo cáo khoa học: Modulation of the enzymatic efficiency of ferredoxin-NADP(H) reductase by the amino acid volume around the catalytic site pptx

Ngày tải lên : 18/02/2014, 17:20
... Design and construction of C266, G267 and L268 single and double FNR mutants Five single mutants of C266, G267 and L268 and a double mutant of C266 and L268 were successfully constructed and confirmed ... for kcat and Km and the calculated kcat ⁄ Km value for NADPH and Fd are summarized in Tables and L268V FNR displayed kcat and Km values for the diaphorase reaction in the region of 0.8 and 2.0 ... approximately 380 and 460 nm and shoulders at 430 and 470 nm The absor- bance maximum of the transition band of the wildtype enzyme at 386 nm was shifted slightly to 381 nm in the C266L, C266M and C266A...
  • 17
  • 609
  • 0
Tài liệu Báo cáo khoa học: A tyrosinase with an abnormally high tyrosine hydroxylase/dopa oxidase ratio Role of the seventh histidine and accessibility to the active site docx

Tài liệu Báo cáo khoa học: A tyrosinase with an abnormally high tyrosine hydroxylase/dopa oxidase ratio Role of the seventh histidine and accessibility to the active site docx

Ngày tải lên : 19/02/2014, 07:20
... genes RSc0337 and RSc1501 TH activity was determined at pH and 0.05% SDS, and DO activity at pH and 0.02% SDS genes, which was opposite to that expected from the blast homologies and designated ... 2-mercaptoethanol and 9% SDS) and heated at 95 °C for before application Electrophoresis was run at 20 °C and a constant current of 15 mA for 20 and 30 mA for  90 Protein bands were visualized ... of tyrosinase and catechol oxidase (proteins NP_518458 and NP_519622, respectively) from R solanacearum In all cases, TH activity was determined at pH with mM L-Tyr and 0.05% SDS, and DO activity...
  • 14
  • 849
  • 0
Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx

Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx

Ngày tải lên : 19/02/2014, 12:20
... IMAGEQUANT software, and depurination was calculated by relating the amounts of the small aniline-fragment and 5.8S rRNA and expressing values as a percentage Reassociation and quantification of ... [3] and 5.8S rRNA and expressing values as a percentage Symbols indicate the experimental data, error bars represent the SD and solid lines represent bestfitted curves (A) RTA, d; RTA R213A, j, and ... The backbone and sidechains of the R213D substitution are shown as stereo images in thick ball and stick and the position of the Arg213 side-chain of the wild-type enzyme is overlayed and shown...
  • 10
  • 616
  • 0
Tài liệu Báo cáo khoa học: Enlarging the gas access channel to the active site renders the regulatory hydrogenase HupUV of Rhodobacter capsulatus O2 sensitive without affecting its transductory activity docx

Tài liệu Báo cáo khoa học: Enlarging the gas access channel to the active site renders the regulatory hydrogenase HupUV of Rhodobacter capsulatus O2 sensitive without affecting its transductory activity docx

Ngày tải lên : 20/02/2014, 01:20
... between HupT and HupUV proteins Lanes and 2, wild-type HupUV; lanes and 4, mutant OD7 HupT was present in lanes and HupT was incubated with any one of the HupUV proteins, a new active band appeared ... eutropha was shown to be very similar to that of standard hydrogenases, with a Fe atom liganded by CO and CN– [16], and the binding of an hydride to Ni and Fe after H2 reduction has recently been demonstrated ... activity and rate of H2 and HD formation by wild-type and mutated HupUV proteins of R capsulatus The values are initial rates corrected for gas consumption by the mass spectrometer Activity and H2...
  • 10
  • 513
  • 0
Tài liệu Báo cáo khoa học: Site-directed mutagenesis of a loop at the active site of E1 (a2b2) of the pyruvate dehydrogenase complex A possible common sequence motif docx

Tài liệu Báo cáo khoa học: Site-directed mutagenesis of a loop at the active site of E1 (a2b2) of the pyruvate dehydrogenase complex A possible common sequence motif docx

Ngày tải lên : 20/02/2014, 23:20
... was from New England Nuclear (Boston, MA, USA) Centrifugal filter devices were purchased from Millipore Bacterial strains and plasmids E coli strain TG1recO and plasmids pKBstE1a and pKBstE1b, expressing ... pBSTNAV/E3) and E2p gene (from pETBstE2) [21] and a subgene encoding a di-domain that comprises the lipoyl domain, the peripheral subunitbinding domain and the linker between them (from pET11d2D and ... motif at the active site is underlined P1 and P2 mark phosphorylation sites and (serine residues) in the E1a chains of eukaryotic PDH and BCDH complexes ODPA and ODPT, E1a chain of PDH complexes with...
  • 10
  • 459
  • 0
Tài liệu Báo cáo khoa học: The unique sites in SulA protein preferentially cleaved by ATP-dependent Lon protease from Escherichia coli ppt

Tài liệu Báo cáo khoa học: The unique sites in SulA protein preferentially cleaved by ATP-dependent Lon protease from Escherichia coli ppt

Ngày tải lên : 21/02/2014, 03:20
... Ala80-Ser81, Leu94-Ser95 and Leu158-Ser159, which were hydrolyzed over 5% (Fig and Table 2) It was remarkable that these cleavage sites contained mainly Leu and Ser at the P1 and P1¢ positions, respectively, ... Met145-Arg146, Ala150-Ser151 and Leu158-Ser159, were 454 W Nishii et al (Eur J Biochem 269) Ó FEBS 2002 ATP, between certain hydrophobic residues, such as Ala, Leu, Met and Phe, and Ser and that cleavages ... 3-min, 30-min, and 3-h incubations in the presence of ATP and 3-h incubation in the absence of ATP in this order Large, medium and small closed arrowheads indicate the fast, medium and slow cleavage...
  • 7
  • 358
  • 0
Tài liệu Báo cáo khoa học: "Selecting the “Right” Number of Senses Based on Clustering Criterion Functions" pdf

Tài liệu Báo cáo khoa học: "Selecting the “Right” Number of Senses Based on Clustering Criterion Functions" pdf

Ngày tải lên : 22/02/2014, 02:20
... from N , and then determines the mean and standard deviation of the criterion function Then, a score is computed for each value of k by subtracting the mean from the criterion function, and dividing ... plateau, and increasing k will have no benefit If P K2 is greater than 1, then an additional cluster improves the solution and we should increase k We compute the standard deviation of P K2 and use ... occurred or more times and had a log–likelihood score of 3.841 or greater, with and without singular value decomposition Details on these approaches can be found in (Purandare and Pedersen, 2004)...
  • 4
  • 361
  • 0
Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx

Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx

Ngày tải lên : 22/02/2014, 07:20
... oxidase and its possible alternatives, (b) the size and extent of the acidic patch on subunit II, and (c) ways of experimentally influencing the kinetic phases during enzyme turnover MATERIALS AND ... wild-type and mutant enzymes (Tables and 2) This analysis reflects and con- firms the kcat values obtained from turnover experiments Some of the mutants showed extremely slow reduction behaviour, and ... (oxidation of cytochrome c) and/ or 605 nm (reduction of heme a), and biphasic time courses were obtained Three independent measurements were done for each donor concentration, and the average was fitted...
  • 9
  • 457
  • 1
Selecting the best anthropometric variables to characterize a population of healthy elderly persons ppt

Selecting the best anthropometric variables to characterize a population of healthy elderly persons ppt

Ngày tải lên : 05/03/2014, 21:20
... (where NOBJ and VA are the number of objects and variables respectively and R is the correlation matrix determinant) and comparing it to X²crit obtained for VA(VA-1)/2 degrees of freedom and the ... subscapular (SST) and suprailiac (SuST) (all in mm), and mid-upper arm circumference (MAC) (cm), were made by the same investigator according to standard techniques of the WHO2 and International ... between elderly men and women for biological, social and behavioural factors affecting changes produced with age in body composition.7 Materials and methods Area of study and subjects On January...
  • 8
  • 544
  • 0
Báo cáo khoa học: Binding of ATP at the active site of human pancreatic glucokinase – nucleotide-induced conformational changes with possible implications for its kinetic cooperativity doc

Báo cáo khoa học: Binding of ATP at the active site of human pancreatic glucokinase – nucleotide-induced conformational changes with possible implications for its kinetic cooperativity doc

Ngày tải lên : 06/03/2014, 00:20
... packed between helices 12 and 15 in the L-domain [29] and stabilized by hydrogen bonds (with Thr332 and Ser336 in helix 12) and hydrophobic interactions (with Val412 and Leu415 in helix 15) A ... obtained for the ligand-free form and the hGK–ATP complex at the end of the simulations (Figs 6B,C and S3; Table S2), also indicating partial closure of the cleft ( 33°) and an apparent domain ... equilibrium thermodynamic parameters, and thus also measurement of the effect of ligands on such conformational equilibria Effect of ATP and Glc on extrinsic ANS fluorescence and limited proteolysis ANS...
  • 15
  • 374
  • 0
Báo cáo khoa học: The chaperone and potential mannan-binding lectin (MBL) co-receptor calreticulin interacts with MBL through the binding site for MBL-associated serine proteases pdf

Báo cáo khoa học: The chaperone and potential mannan-binding lectin (MBL) co-receptor calreticulin interacts with MBL through the binding site for MBL-associated serine proteases pdf

Ngày tải lên : 07/03/2014, 05:20
... opsonization and phagocytosis (e.g the C3b receptor) Receptors for MBL and C1q are also assumed to play a role in opsonization and clearance and have been the subject of intensive research Several candidate ... possess Ca2+ binding, lectin-like and polypeptide binding properties [61–67] Calreticulin has been reported to be a candidate co-receptor for the collectins and C1q and to be present on cell surfaces ... target/apoptotic cell recognition depends on multiple factors and ligands, and that it has an inherent redundancy, in order to achieve maximal specificity and safety in self/non-self discrimination Thus, the...
  • 12
  • 429
  • 0
Báo cáo khoa học: Interactions of imidazoline ligands with the active site of purified monoamine oxidase A potx

Báo cáo khoa học: Interactions of imidazoline ligands with the active site of purified monoamine oxidase A potx

Ngày tải lên : 07/03/2014, 10:20
... kynuramine and MPTP [29] Difference spectra and binding curves When ligands bind to the active site of MAO-A, the environment of the flavin is altered, resulting in spectral changes [24] The I2BS ligands ... al (1997) for membrane-bound MAO-A and MAO-B [5] Spectral changes and the alteration of the redox properties of the flavin (Figs and 3) confirm that I2BS ligands bind FEBS Journal 274 (2007) 1567–1575 ... samples with the ligands used in this study are included in Table It has been proposed that I2BS ligands bind both to the MAO active site, thereby inhibiting the enzyme, and to a second site...
  • 9
  • 473
  • 0