... origin [14], the feedback inhibitor dTTP wasbound inthe substrate pocket, similar tothe bindingof dTTP tothe D. melanogaster multi-substratedeoxyribonucleoside kinase [16], despite the ... triphosphate to the 5¢-hydroxyl group of thymidine, forming dTMP. Human TK1 iscytosolic and its activity is absent in resting cells, appears in late G1,increases in S phase coinciding with the increase ... during the cell cycle, in close correlationwith the rate of DNA synthesis, with low dNTP levels in G1cells increasing during S phase, generally withdTTP being the most abundant and dGTP the...
... suspect is the source of the crime stain’(H1), ‘one of the n − 1 other individuals inthedatabase is the sourceof the crime stain’ (H2 n),and‘thesourceofthecrimestainisamong the N − n individuals ... sizeof thedatabase or the size of the population ofpotential sources. A second item of informationpertains tothe individuals inthedatabase other than the suspect, that is, the fact that these ... non-matching individuals in a database tends to increase the strength of the evidence against the suspect.As pointed out at the end of the previous section, the logic of the strengthened evidence...
... sugars. To identify the transport substrate of DmNST, a DNAfragment containing the entire c oding region was ampli®edby PCR and inserted into the expression vector pMKIT-neoutilizing the EcoRI ... (Millipore, Be dford,MA, USA) and the radioactivity retained on the ®lterwas measured.Staining with lectin and antibodyLectin staining and indirect immuno¯uorescence stainingwere carried out as described ... Grioniasimplicifolia lectin II (GSII) or peanut agglutinin (PNA)(EY L aboratories, San Mateo, CA, USA), and furtherincubated with monoclonal anti-HA Ig to detect the transporter protein expressed inthe cells....
... the line of inquiry generally, and the special suitabilityof it to individual minds, there is a further use, which inthe present day belongs to it in common with allinquiries into the history ... no others, inthe room adjoining tothe Printing-House, between the hours of ten in the morning and two inthe afternoon, to preach eight Divinity Lecture Sermons, the year following, at St. ... benevolence; their joy in death. The points which he depicts in his satire are, their credulity in giving way to Peregrinus; their unintelligent belief in Christ and in immortality; their factiousness in...
... Neo is told that he'sright to think that the world is not what it seems. However, something always happens to convince the hero to change his mind. InThe Matrix, Neo goes back to work ... being either sought out or roped into peculiarcircumstances is a common one in heroic tales; frequently, the would-be hero is swept up intosomething that he initially appears to have nothing ... DepartureBoth stories begin with calls to adventure for their heroes into situations those heroes neverexpected; in fact, at the outset, neither Neo inThe Matrix, nor Luke in Star Wars, has...
... companies. Initially, the women, as well as their supervisors were informed regarding the purpose of the study and then the questionnaires were handed out tothe women who were interested in participating. ... 15-25% of the women consider the sex of the doctor to be an important factor in choosing their gynecologist.3,10,11 Furthermore, gender could make a significant difference inthe type of ... are ahead inthe women’s preferences, whereas half of the women think that the sex factor is rather insignificant. The older age at the first visit and the sparse physical breast examination...
... smoking, physical exercise other than walkingand walking (Model 3), the lower HRQL was independ-ently linked to overweight only in females. Similar resultswere obtained in model 4 which also included ... possible to ascertain the subtle differ-ences which contribute to a change inthe perceived qual-ity of life in individuals with increased body weight, andparticularly inthe obese.Conclusion The ... compared to identify the factors leading to increased body weight and obesity and, consequently, to the impairment of health-related quality of life.Competing interests The authors declare that they...
... for intervention.Can you corroborate these findings from local independent sources? In order to determine whether to apply the study findings to our field setting requires independent informationfrom ... situ-ation. In order for findings to be useful, they should to besimilar tothe current situation or provide strong historicalcontext that can assist in determining their relevance to the current ... the results in proportion tothe likeli-hood of sampling.Did the investigators succeed in interviewing a large proportion of the chosen sample?Failure to interview a large proportion of the...
... primarily followed their owndefinitions of different scoring values, such as excludingcertain scores (see examples in table 1). They find the def-initions incorrect. If the veterinarian strictly ... feelings,experiences, and thoughts on the subjects and the observed [9]. However, we acknowledge the risk of influ-ential interaction between the interviewer and the inter-viewed during the interviews ... could influence the statements of the interviewed e.g., the use of leading ques-tions. In the phase of analysis it is important to determine whenno additional information can be extracted from the...
... colleagues on the world. The Association has the role of coordinating the activities of the members in order to protect the interests of the members and improve the position of Vietnam inthe international ... experts involving in Freight Forwarding and having high professional skills and abilities to contribute tothe realization of the objectives and duties of the Association, may be invited to join the ... opportunities inthe international economic integration process today.1.6.2. To enterprisesFreight forwarding in particular and Logistics in general are the keys for enterprises to deal the input...
... ADAPTING THE DIALOGUE TO THEIR LIVES.(Using prompts)Explain tothe students that they are going to do the dialogue again in pairs, using their own information. This time the teacher is going to ... would like to find out more knowledge of the following topics and about the following topics for their use them regularly in their teaching: teaching: TOPICS %Testing grammar 78Correcting students’ ... with the next finger.Squeeze the two fingers together to show the contraction (e.g. “I’ve“).[b] missing worde.g. “I’ve got a bike.”Point tothe finger which represents the missing word in the...