iib iiia receptor inhibitors or low molecular weight heparins
báo cáo khoa học: "The potential benefits of low-molecular-weight heparins in cancer patients" ppsx
... Comparison of LowMolecular -Weight Heparin versus Oral Anticoagulant Therapy for the Prevention of Recurrent Venous Thromboembolism in Patients with Cancer (CLOT) Investigators: Low- molecular- weight ... Differentiating low- molecular- weight heparins based on chemical, biological, and pharmacologic properties: implications for the development of generic versions of low- molecularweight heparins Semin ... (minor) 3.6 (major) Enoxaparin 40 mg SC 25–31 days 4.8 4.7 (minor) 5.1 (major) 178 Dalteparin 5,000 IU OD plus GCS for days 16.3 0.9 (minor) 1.8 (major) Dalteparin 5,000 IU SC OD plus GCS for...
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Báo cáo y học: "Measuring the anticoagulant effect of low molecular weight heparins in the critically ill" pps
... MC has received honoraria, travel funding, consultancy fees and research support from Leo Laboratories, Sanofi-Aventis and Pfizer Acknowledgement MC is a Career Investigator of the Heart and ... Meijers J, Vroom MB, Buller HR, Levi M: Bioavailability of subcutaneous low- molecularweight heparin to patients on vasopressors The Lancet 2002, 359:849-850 Rommers MK, Van Der Lely N, Egberts TCG, ... (total recruitment 14 patients), nonrandomized pilot study, the authors performed careful pharmacokinetic analysis of the anti-factor Xa heparin levels found after subcutaneous administration of...
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Báo cáo khoa học: Weak oligomerization of low-molecular-weight protein tyrosine phosphatase is conserved from mammals to bacteria pot
... basis for the activation of a low- molecular weight protein tyrosine phosphatase by adenine Biochemistry 39, 1234–1242 Xu H, Xia B & Jin C (2006) Solution structure of a low- molecular- weight protein ... authors and readers, this journal provides supporting information supplied by the authors Such materials are peer-reviewed and may be re-organized for online delivery, but are not copy-edited or ... cysteines confer a peculiar redox regulation to low molecular weight protein tyrosine phosphatase in response to platelet-derived growth factor receptor stimulation J Biol Chem 276, 33478–33487 Rigacci...
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Báo cáo y học: "Hemostasis during low molecular weight heparin anticoagulation for continuous venovenous hemofiltration: a randomized cross-over trial comparing two hemofiltration rates" pdf
... nadroparin at initiation of CVVH, or 3800 IU when body weight exceeded 100 kg, followed by a continuous infusion in the extracorporeal circuit before the filter of 380 or 456 IU/h, respectively After ... anti-factor Xa and anti-thrombin activities of a low molecular weight heparin (nadroparin) Thromb Haemost 1998, 79:1162-1165 Lim W, Dentali F, Eikelboom JW, Crowther MA: Meta-analysis: low- molecular- weight ... needed and heparins are the classic choice Both unfractionated heparin and low molecular weight heparins (LMWHs) are used LMWHs have the advantage that their pharmacokinetics are more predictable...
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Báo cáo khoa học: NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B–NS3 protease ppt
... inhibitor (2FP7) [5] in complex with peptide inhibitors or BPTI [4–6] are thus suitable starting points for modelling the complexes with the low molecular mass inhibitors of this study Inhibitor ... high-affinity inhibitors for WNV NS2B–NS3pro is nontrivial In one study, competitive inhibitors with an inhibition constant of NMR analysis of the West Nile virus protease Fig Synthetic inhibitors 1–3 ... to discover nonpeptidic inhibitors with inhibitory activities much below lm [13,14], with an EC50 value of 0.85 lm being reported for the most active compound [15] In order to improve our understanding...
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In vitro and in vivo study of ABT 869 in treatment acute myeloid leukemia (AML) alone or in combination with chemotherapy or HDAC inhibitors insight into molecular mechanism and biologic characterization
... other FLT3 inhibitors 55 3.3.2 Overexpression of FLT3, p-FLT3 receptor or multi-drug resistant related proteins or mutations in KD were not responsible for resistance to FLT3 inhibitors in MV4-11-R ... USA and for giving your support I am grateful to the flexible and stimulating work environment you created Dr Hanry Yu, my co-supervisor for your gracious commitments, for supporting my works, especially ... shRNAmir individual constructs are form the laboratory of Dr Greg Hannon at Cold Spring Harbor Laboratory (CSHL) which created an RNAi Library comprised of multiple shorthairpin RNAs (shRNAs) specifically...
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Effects of longterm ingestion of cd polluted rice or low dose cd supplemented diet on the endogenous cop
... Cadmium, World Heath Organisation, Geneva 2) WHO (1992b) Environmental Health Criteria 135 Cadmium-Environmental Aspect, World Heath Organisation, Geneva 3) Friberg, L., Piscator, M., Nordberg, ... consisting of 28% purified and 72% ordinary rice (unpolluted or Cd-polluted rice prepared by Oriental Yeast Co Ltd., Tokyo, Japan) Group I was fed a mixture of purified and ordinary rice and was used ... for 16 hr or more prior to death The experiment was terminated at month 22 because the total number of surviving animals in the 20-ppm CdCl2-treated group reached the minimum necessary for subsequent...
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Báo cáo khóa học: C-, 15N- and 31P-NMR studies of oxidized and reduced low molecular mass thioredoxin reductase and some mutant proteins docx
... Raton, Florida ă 18 Mulrooney, S.B (1997) Application of a single plasmid vector for mutagenesis and high level expression of thioredoxin reductase and its use to examine avin cofactor incorporation ... conformations to more completely favour the FR form In this conformation, the avin uorescence is strongly quenched by the binding of 3-aminopyridine adenine dinucleotide [14] The FAD of thioredoxin ... Biochem 271) the low molecular mass type, which is also found in other bacteria, fungi and lower plants The enzyme found in most higher organisms is of a high molecular mass form The crystal structure...
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Báo cáo khoa học: Piezoelectric sensors based on molecular imprinted polymers for detection of low molecular mass analytes potx
... Similarly, synthetic receptors formed by molecular imprinting can be used to recognize biological or nonbiological molecules on QCM sensors Here the imprint of a template molecule is formed on a synthetic ... exposed the receptor to 180 Da sugars A reproducible frequency change was observed which was ascribed to the conformational change of the receptor upon ligand binding Similarly conformational ... to a bead or other additional mass load to increase the molecular mass of the complex detected [24] Other Detection of low molecular mass analytes approaches utilize a coupled assay format in...
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Báo cáo khoa học: High molecular weight kininogen binds to laminin – characterization and kinetic analysis pot
... factor XII, high molecular weight kininogen (HK), prekallikrein and factor XI, but only factor XII and HK interact directly with the ECM However, in the plasma, prekallikrein and factor XI form ... although factor XII recently was shown to bind to fibronectin (FN) [8], and several endothelial cell membrane proteins have been suggested as receptors for HK, including the globular C1q receptor [9,10] ... binding assay was performed in buffer supplemented with gelatin or albumin Accordingly, and because the correction for nonspecific binding in these previous studies was performed by the subtraction...
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Báo cáo khóa học: Protein assembly of photosystem II and accumulation of subcomplexes in the absence of low molecular mass subunits PsbL and PsbJ pdf
... and CP43 core proteins as well (Fig 1B) The presence of minor amounts of D2 in both DpsbE and DpsbF supports the suggestion that the D2 protein is a component of the primary receptor for the synthesis ... visible light below 500 nm, which was defined by using LS500S and LS700S filters (Corion Corp., Holliston, MA, USA) in front of the slide projector The emission between 600 and 780 nm was recorded Thylakoid ... thylakoids from mature leaves contained all major PSII core proteins (Fig 1A), but in lower amounts than in the controls The mean content of the major PSII core proteins (D1, D2, PsbE, CP43 and CP47)...
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Báo cáo khoa học: Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes Formation of modified and oxidized particles pot
... that neither glucose nor low levels of Cu2+ induce significant Trp or Lys modification Furthermore the absence of any peak shifts in the Trp fluorescence spectra imply only minor, if any, structural ... experiments performed here were carried out with Cu2+ : LDL ratios ( 1.2 : 1) that are well below the lower threshold of 5–6 postulated by the these workers, and hence the absence of any stimulatory effect ... These data support a previous suggestion [68] that covalent modification (glycation), in the absence of lipid or protein oxidation or antioxidant consumption, is sufficient for the formation of foam...
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Báo cáo hóa học: " Risk factors for low birth weight in Botucatu city, SP state, Brazil: a study conducted in the Public Health System from 2004 to 2008" pptx
... of prenatal care visits ¹ 22 or less 1–3 23–27 or more 28–31 or more 32–36 or more 37 or more or more ¹ Adequacy from PHPN and Kessner Index [20,25,26] Ethics Following the ethical principles ... correlation between obesity and overweight during adolescence with low birth weight, reported approximately 20% of this diagnosis in the study population, which led the authors to point out for ... newborns in each group as follows: low weight newborns (LWNB) and a control group (weight ≥ 2500 g) Secondary data from 2004 to 2008 were collected using the Live Birth Certificate (LBC) and records...
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Báo cáo khoa học: " Variation in the molecular weight of Photobacterium damselae subsp. piscicida antigens when cultured under different conditions in vitro" pot
... ,4991 loiborciM norivnE lppA hsif rof yticinegohtap ni elor sti dna adicicsip alleruetsaP yb ekatpu norI EA oznaroT ,LJ ajraB ,LM someL ,LJ edlamoR ,B soñiragaM 22 792-982 ,12 ,6991 gohtaP borciM ... evitcetorp tnatropmi era adicinomlas sanomoreA fo snietorp enarbmem retuo detaluger-norI EA sillE ,DI tsriH 41 102-981 ,51 ,3002 htlaeH minA tauqA J ASU ,anaisiuoL ni derutluc ssab depirts dirbyh morf ... ,P selasoR-zaíD 01 982-582 ,421 ,4991 tteL loiborciM SMEF ortiv ni nworg adicicsip alleruetsaP yb desserpxe edirahccasylop raluspaC F odagergnoC ,EA oznaroT ,DM lojuP-nomiS ,LJ edlamoR ,B soniragaM...
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Báo cáo y học: "Intra-articular injections of high-molecular-weight hyaluronic acid have biphasic effects on joint inflammation and destruction in rat antigen-induced arthritis" ppt
... and stored in 6% formaldehyde In order to ensure an optimal impregnation with formaldehyde, the adhering remainders of the long bones were kept very short (approximately 1.0 cm above and below ... inflammation score was more pronounced in R682 Score * nonarthritic untreated HA-treated untreated HA-treated Histological scores In the short-term test, hyaluronic acid (HA)-treated scores antigen-induced ... of the experimental results, reviewed the manuscript, and organised financial support and laboratory space for the experiments PP performed and summarised all histological analyses, and reviewed...
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Báo cáo y học: " Arthritis, osteomyelitis, septicemia and meningitis caused by Klebsiella in a low-birth-weight newborn: a case report" pps
... this article as: Ghorashi et al.: Arthritis, osteomyelitis, septicemia and meningitis caused by Klebsiella in a low- birth -weight newborn: a case report Journal of Medical Case Reports 2011 5:241 ... achieved normal developmental milestones and weight gain, without adverse effects or hospital readmission during three years of follow-up Figure Chest X-ray obtained on the seventh day of oral antibiotic ... informed consent was obtained from the patient’s next-of-kin for publication of this case report and any accompanying images A copy of the written consent is available for review by the Editor-in-Chief...
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Báo cáo y học: " Recurring staphylococcal scalded skin syndrome in a very low birth weight infant: a case report" pptx
... Journal of Medical Case Reports 2009, 3:7313 http://jmedicalcasereports.com/jmedicalcasereports/article/view/7313 very low birth weight (VLBW) Furthermore, we emphasize the importance of early diagnosis ... switching to oral cefaclor [13] Rieger-Fackeldey et al [14] report SSSS in an extremely low birth weight infant with a relapse weeks after the primary infection Another case report mentions SSSS ... placenta We found no clues of infection clinically or in laboratory tests Amoxicillin-clavulanic acid was continued for days and gentamicin for days On day 19 of life, a mm red skin lesion with...
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Báo cáo khoa học: "Endocrine Profiles, Haematology and Pregnancy Outcomes of Late Pregnant Holstein Dairy Heifers Sired by Bulls Giving a High or Low Incidence of Stillbirth" ppt
... substrate supply This was reported to be a major factor of altered or reduced foetal growth in sheep (McMillen et al 2001) In addition, a number of hormones and growth factors including progesterone, ... calving performance sorted by groups is presented in Table The post-mortem examination of the stillborn calves (from animals nos 145 and 465) revealed no pathological changes or malformation, while ... these hormonal parameters might be used for monitoring of the foetal well being (for a review, see Kindahl et al 2002) Measurements of bovine pregnancy specific protein (bPSPB) may be useful for prediction...
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Báo cáo y học: " Proviral integrations and expression of endogenous Avian leucosis virus during long term selection for high and low body weight in two chicken lines" ppt
... among F9 birds was significantly correlated with low body weight for the females but not for males The conserved correlation between high expression and low body weight after generations of intercrosses, ... among F9 birds was significantly correlated with low body weight for the females but not for males The conserved correlation between high expression and low body weight in females after generations ... breed used for egg production and broiler breeding The selected lines have been maintained as closed populations by continuous selection for low or high body weight at 56 days of age for more than...
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Bóa cáo y học: "Arginine-vasopressin in catecholamine-refractory septic versus non-septic shock in extremely low birth weight infants with acute renal injury" potx
... echocardiography was performed in all infants to assess left ventricular function All infants had an arterial line in place for invasive monitoring of arterial blood pressure Daily laboratory monitoring included ... defined as cardio-circulatory failure with concomitant organ dysfunction (renal injury, hyperlactataemia) without an infectious etiology Low cardiac output was defined as a shortening fraction ≤ 25% ... creatinine) or urine output
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