... music), taking into account the director’s – and, therefore, the composer’s – intentions, the narrative content ofthe film, andthe overall strategy ofthe director in constructing the multifaceted ... valid to say that the music projects the meaning ofthe image or the image projects the meaning ofthe music), then the multimedia example has passed the similarity test andthe relationship ... theoretical – of film music perception andthe role of music in film, referencing some ofthe most significant research investigating the relationship between sound and image inthe cinematic context....
... regions ofthe proteininvolved in interaction with Cdk2 and cyclin A: 1, domain 1 interacting withcyclin A; 2, a linker helix involved in bindingboth cyclin A and Cdk2; 3, domain 2 inter-acting ... Cdk2,p27Kip1binds and rearranges the amino-terminal lobe and also inserts into the catalytic cleft, mimicking ATP in the context ofthe cyclin A–Cdk2 complex [120]. In contrast, the unbound p27Kip1Cdk-inhibition ... forp27Kip1binding to the Cdk2–cyclin A binary complex and shows the importance of both preformed, but tran-sient structure inthe linker region andthe flexible nat-ure of domains 1 and 2 for the efficient...
... The Role of Higher Education in Economic Development Page 6 of 12 Identifying Needs of Business and Industry Higher education connects workforce development to the economic developmentofthe ... economic developmentofthe region. Together, the institutions of higher education invite the public and private sectors, including business and industry, education, civic groups, not-for-profits, ... workforce by offering instructional programs, matching instruction to the needs of business and industry, and helping individuals learn throughout their lives. Instructional Programs Teaching excellence...
... domain structure. Schematic of Vrp1p showing the Vrp1p truncations and mutant proteins used in this study and theirvarious known domains: actin-bindingdomains, Hof one trap (HOT) domain, and LBD. ... suggests that inter-actions mediated by these two domains are directlyimplicated in polarization ofthe yeast actin cytoskele-ton. The presence ofthe novel actin-binding VH2-Cdomain in C-Vrp1p364)817may ... C-Vrp1p364)817may explain why mutations in the N-terminal actin-binding WH2 domain (WH2-1)or even deletion ofthe entire N-terminal module of Vrp1p did not significantly perturb the activity of Vrp1p in polarization...
... productive binding of steroid substrates: in the first, a (small) sub population of enzyme bindsdirectly the steroid inthe reactive conformation, with the remainder ofthe enzyme binding the unreactiveconformation. ... His181 and His184 are important inthe binding of coenzyme, steroids, nitro-aromatic ligands andthe substrate 2-cyclohexen-1-one. The H181A and H184A enzymes retain activity in reductive and oxidative ... progesterone, 1,4-androstadiene(Fig. 1A) and 2-cyclohexen-1-one indicate that theseligands bind above the si face ofthe FMN isoalloxa-zine ring and are held in position by hydrogen bondinteractions...
... minute, Aban. You were wandering, lost, down there inthe dark- THE DREAMING CITY GLASGOW 2020 ANDTHE POWER OFMASS IMAGINATION THE DREAMING CITY GLASGOW 2020 ANDTHE POWER OFMASS IMAGINATION—eye, ... history of change and reinvention. The choice the city has is not between changing and not changing, but about the nature of —INTRODUCTION—— THE DREAMING CITY ANDTHE POWER OFMASS IMAGINATION— THE ... attain popular appeal and so declined the US government’s offer of a free transfer (and monopoly) of the administration ofthe internet.52 In cities, theof cial future is a reection of who...
... progress in our knowledge ofthe bio-synthesis of DIMs and PGLs, thein vivo functions of these FadD proteins in this pathway remain to beestablished and ⁄ or completed. For instance, the involvement ... topromote the transfer ofthe p-HB moiety ontoPKS15 ⁄ 1 [16,18].To examine the involvement of FadD29 inthe bio-synthesis of DIMs and PGLs, we took advantage of the existence inthe laboratory of ... becontrolled in vivo by specific interactions betweenFadD29 and PKS15 ⁄ 1 on the one hand, and FadD26 and the FasI system on the other hand. Further inves-tigations, including protein interaction...
... existing relationships ofthe intermediary with the business, the business owner, or other involvedparties. The intermediary then uses this information about the initial quality ofthe small business ... services),3) the size ofthe borrowing firm and its outside finance options, 4) the structure ofthe banking industry, and 5) the trust that is built up between the bank andthe small business. Further ... another important aspect of small business finance the financial intertwining of owners and their businesses (Ang 1992). Outsideinvestors and intermediaries often put considerable weight on the...
... running in opposite direc-tions. The monomer association involves the ATP-usingC-terminal domains interacting near the base of that side of the wedge outside; the N-terminal domains form the ... domain and then rebinding to a second mobile lipoyl domain fasterthan releasing from the singly held state [21]. Each of the lipoyl domains of E2 is concentrated within the exterior of the complex ... Requisite interactions of PDK3 and PDP1 withL2, the inner lipoyl domain of E2, are shown to engageextensive regions ofthe surface of L2 and to require the lipoylprosthetic group and, in thecase of...
... substrates, including vincristine, requireGSH for their transport and that vincristine inhibits the high affinity DNP-SG transport inthe presence but not in the absence of GSH [12,45,46]. Thus the effect ... Unoninh; 1 ¼ ni¼ 2 ð3Þwhere I is the concentration ofthe inhibitor, IC50is the inhibitor concentration producing 50% inhibition of the inhibitable component, U0is the uptake inthe absence ... 1A). Uptake of [3H]cGMP in the absence of ATP but inthe presence ofthe nonhydrolysableATP analogue, ATP-c-S, was less than 5% ofthe uptake in the presence of ATP. The amount of [3H]cGMP...
... throughout the country. The governor generals of Finland andthe Caucasus were killed, and there were many assassinations in other border areas, including Ar-menia and Poland, andin minor cities.Following ... (semi-Trotskyite in the 1970s and early ’80s, and ultranationalist inthe 1990s). The political wing of ETApolled 12 percent ofthe votes inthe Basque country inthe generalelections of 1996, in comparison ... as the ultima ratio of rebels against real tyranny.ZEALOTS AND ASSASSINSPolitical murder appears inthe earliest annals of mankind, including the Bible. The stories of Judith and Holofernes, of...
... recorded in the shells of foraminifera, whether they live at the surface or the bottom ofthe ocean. One ofthe great achievements ofthe pastfew decades has been the confirmation ofthe Milankovitchtheory. ... paperspublished inthe 1960s he was able to recognize six mass- extinction events inthe Phanerozoic. By the beginning of the 1980s the database had improved further, and Jack Sepkoski of the University of ... Professor of Geology at the University of Birmingham andthe author of a hugerange of scientific books and papers including Great Geological Controversies (1992) and Mass Extinctions and their...
... changing behaviours to support the team and company goals therefore increasing the bottom line. In other areas of training Jan has excelled in defining criti-cal business needs and delivering ... finding a different way? The above listed mind probing questions will lead to thoughts of finding better ways of doing things by simplifying and improving the ways of doing things, discarding ... continue doing an activity as a routine but the reason for doing so is no longer exits. Creativity is breaking away from habitually doing things and finding a better and easier way of doing the...