identification search for new approaches molecular markers dna vs biochemical descriptors
Search for new types of deoxyribozymes and development of human topoisomerases inhibitors on the basis of oligonucleotides
Ngày tải lên :
11/09/2015, 16:06
... existing in nature for DNA, makes DNA an ideal molecule for information storage and transfer Yet, it is precisely these characteristics, the ones that are most attractive for building the ideal ... Components for Some DNA Aptamers and DNA Enzymes Natural DNA serves almost without exception as an informational macromolecule that exists primarily as a base-paired duplex Single- tranded DNAs are ... random dna sequence Biotin modification double stranded DNA DNA pool DNA cloning and sequencing Figure 1-2 In vitro selection process of deoxyribozymes: A population of single stranded DNA molecules...
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Systemic risks of genetically modified crops the need for new approaches to risk assessment
Ngày tải lên :
17/02/2016, 11:38
... decision making [58,59,51,60] Broader approaches for assessing the implications of GM crop agriculture New risk concepts that lay the ground for more holistic approaches to assess risks beyond the ... modified crops Edited by: Halford N New York: John Wiley 2006:225-239 Stein AJ, Rodríguez-Cerezo E: The global pipeline of new GM crops: implications of asynchronous approval for international trade ... Commission, Joint Research Centre, Institute for Prospective Technology Studies, Sevilla; 2009 Rodgers J: Asilomar revisited Mosaic 1981, 19-25 Singer M, Soll D: Guidelines for DNA hybrid molecules...
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báo cáo khoa học: " Complete chloroplast genome of Oncidium Gower Ramsey and evaluation of molecular markers for identification and breeding in Oncidiinae" pot
Ngày tải lên :
12/08/2014, 03:21
... structure and sequence information provides a resource for primer design for other cpDNA sequencing by PCR [6] This approach has been used for the sequencing of two bamboo cpDNA genomes [7] As chloroplast ... plants, chloroplast DNA (cpDNA) is in many respects the genome of choice for taxonomic studies in orchids [2] as well as other species [4,5] There are many advantages to using cpDNA for taxonomy and ... 94°C for 30 s, at 55°C for 30 s and at 72°C for 90 s The PCR products were sequenced DNA sequencing was carried out with the Big-Dye Terminator Cycle Sequencing kit using an ABI Prism 3,700 DNA...
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Báo cáo y học: "Identification of candidate predictive and surrogate molecular markers for dasatinib in prostate cancer: rationale for patient selection and efficacy monitoring" doc
Ngày tải lên :
14/08/2014, 08:20
... the use of molecular biomarkers To support the development of dasatinib for use in prostate cancer we employed prostate cancer cell lines as preclinical models to identify molecular biomarkers whose ... Article R255 Wang et al R255.3 - CK5 - PSA - AR Figure Identification of biomarkers correlated with sensitivity to dasatinib Identification of biomarkers correlated with sensitivity to dasatinib (a) ... Rationale for patient stratification in dasatinib prostate cancer trials Based on their differential expression, we reasoned that CK5, PSA, and AR could serve as predictive biomarkers for identification...
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DEVELOPMENT AND APPLICATION OF NEW APPROACHES FOR STUDIES OF INFLUENZA INDUCED INFLAMMATION AND DNA DAMAGE
Ngày tải lên :
09/09/2015, 08:16
... learn more about the potential for influenza to induce DNA strand breaks, we performed a comet assay, a method that is well established for directly measuring physical DNA single stranded lesions ... host DNA damage to a poorer prognosis if damaged DNA is not efficiently repaired While results shown here point to a role for DNA repair in preventing cytotoxicity caused by RONS-induced fork ... sites of DSBs to form the Ku heterodimeric complex Ku complex then protects exposed DNA ends and recruits DNA- PKcs for downstream NHEJ processing [67] Deficiency in Ku can lead to DNA degradation...
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DEVELOPMENT AND APPLICATION OF NEW APPROACHES FOR STUDIES OF INFLUENZA INDUCED INFLAMMATION AND DNA DAMAGE
Ngày tải lên :
30/09/2015, 06:20
... Contrast index DNA binding domain DNA damage response Deoxyribonucleic acids DNA- dependent protein kinase DNA- dependent protein kinase catalytic subunit days post infection DNA double strand ... histones that form DNA repair foci at the sites of DNA strand breaks in the lung tissue of infected mice DNA repair foci are induced in lung epithelial cells and infiltrating immune cells for prolonged ... malondialdehyde) can also induce damage in DNA to form strongly mutagenic etheno -DNA adducts (Linhart, Bartsch, and Seitz 2014) Taken together, numerous forms of DNA modification can occur upon exposure...
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Báo cáo khoa học: "Collapsed Consonant and Vowel Models: New Approaches for English-Persian Transliteration and Back-Transliteration" ppt
Ngày tải lên :
23/03/2014, 18:20
... transliteration, and a novel alignment algorithm applicable for transliteration Our new transliteration method ( CV- MODEL 3) outperforms the previous approaches for English to Persian, increasing word accuracy ... of Transliteration Approaches The results of our experiments for transliterating English to Persian, using GIZA ++ for alignment generation, are shown in Table CV- MODEL outperforms all three baseline ... corresponding improvement for the Large corpus is 12.8% to 74.2% (p
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nuallain - the search for mind - a new foundation for cognitive science (cromwell, 2002)
Ngày tải lên :
03/04/2014, 12:07
... pause for breath for a moment These themes have emerged: • The search for a single underlying explanatory principle for all that is • The idea that abstract operations on symbols can inform about ... 209 210 211 212 215 218 Part II - A New Foundation for Cognitive Science 219 Symbol Systems 221 Consciousness and Selfhood 228 Cognitive Science and the Search for Mind 253 7.1 7.2 7.3 8.0 8.1 8.2 ... unified theory of language www.nousresearch.com/mind3 explored spatial cognition, and with it one future path for AI research suggested by this book And yes, it’s time for that anti-acknowledgement...
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Báo cáo hóa học: " HPV vaccine: an overview of immune response, clinical protection, and new approaches for the future" pdf
Ngày tải lên :
18/06/2014, 16:20
... biological evolution, HPVs are successful infectious agents They induce persistent infections without frequent and serious complications for the host and shed virions for transmission to other ... such as yeast (for quadrivalent vaccine) or baculovirus (for bivalent vaccine) In this way L1 over-expressed proteins spontaneously self-assemble into VLPs that: resemble the conformation of authentic ... neutralizing titers that are greater for the homologoustype virus than for a heterologous-type papillomavirus The lower immune response to heterologous HPVs could severely limit the breadth and...
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Báo cáo hóa học: " New Bending Algorithm for Field-Driven Molecular Dynamics" pptx
Ngày tải lên :
22/06/2014, 00:20
... ,z0 ), thus the dynamical, uniform, and field-driven stretch can be performed From the above idea, one can search a coordinate transformation for the bending purpose For the simplest bending case, ... concluded in ‘‘Conclusion’’ section The Coordinate Transformation For a tension simulation, one may view the stretch as a coordinate transformation described as x ¼ x; y ¼ y; z ¼ z: a The Jacobian ... between x and x0 in the horizontal plane is d For D \ 0, there are three different real roots; for D = 0, there are triple or double real roots; and for D [ 0, there is only one real root and two...
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Báo cáo hóa học: " Research Article New Approaches for Channel Prediction Based on Sinusoidal Modeling" pdf
Ngày tải lên :
22/06/2014, 23:20
... (Swedish Foundation for International Cooperation in Research and Higher Education) scholar for studying at Chalmers From 2001 to 2004, he was a Research Engineer at Ericsson Research, Stockholm, ... the relative performance instead In this figure, the LP has the best performance The conditional LMMSE predictor has the worst performance The unconditional LMMSE predictor outperforms the conditional ... Viberg, “Two new approaches for channel prediction based on sinusoidal modeling,” EURASIP Journal on Applied Signal Processing, special issue on advances in subspace-based techniques for signal...
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Doctoral thesis summary study on rice breeding for brown planthopper resistance using molecular markers
Ngày tải lên :
13/07/2014, 16:14
... applying molecular markers F1 F2 BC1F2 BC3F5 BC3F6 BC3F7 3.2 Screening the BPH resistant genes by use of molecular markers 3.2.1 DNA extraction and purification Figure 3.1 DNA conconcentration and DNA ... without BPH resistant gene, but has some economic traits 2.2.3 Information collection of molecular markers Most of molecular markers used in this study were collected from the web http://www.gramen.org/cho ... molecular markers linked with the genes and mapping the resistant genes in Vietnam Some molecular markers have linkage with the BPH resistant genes have been identified Constructing a linkage map for...
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Báo cáo lâm nghiệp: "Molecular markers provide evidence for long-distance planting material transfer during plantation establishment of Dalbergia sissoo Roxb. in Nepal" pot
Ngày tải lên :
08/08/2014, 01:22
... Tropical Forest Genetics, Commonwealth Forestry Institute and Forest research Centre, Oxford and Harare, 1984, pp 597–603 [11] Taberlet P., Gielly L., Pautou G., Bouvet J., Universal primers for amplification ... was at 94 °C for 15 min, followed by 35 cycles, each consisting of 94 °C for min, 51 °C to 64 °C for min, and 72 °C for After successful amplification, the PCR products were used for restriction ... populations Molecular gene markers can be powerful tools to assess the evolutionary past of populations [9] and to infer the origin of material, which has been transferred by humans We used molecular markers...
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Báo cáo lâm nghiệp: "of morphological characters and molecular markers for the analysis of hybridization in sessile and pedunculate oak" pps
Ngày tải lên :
08/08/2014, 18:21
... (Matt) Liebl) Allgemeine Forst- und Jagdzeitung Aas G Traubeneichen 162, 141-145 Anderson E (1953) Introgressive hybridization Biol Rev 28, 280-307 Avise JC (1994) Molecular markers, natural history ... (1966) Hybridization as a source of variation for adaptation to new environments Evo- lution 20, 315-336 Moreau F, Kleinschmit J, Kremer A (1994) Molecular differentiation between Quercus petraea ... If these types of markers cannot be used to directly identify the hybrids, nevertheless the differences in frequencies between species can be exploited to estimate, in mixed forests, the parental...
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Báo cáo y học: "Contribution for new genetic markers of rheumatoid arthritis activity and severity: sequencing of the tumor necrosis factor-alpha gene promoter" docx
Ngày tải lên :
09/08/2014, 10:20
... evaluated and genotyped for 10 SNP markers, and five of these markers were excluded due to failure to fall within Hardy-Weinberg equilibrium or to monomorphism For the remaining five markers (positions ... and radiological damage for those with more than 10 years of disease duration (DD) Page of 10 (page number not for citation purposes) Available online http://arthritis-research.com/content/9/2/R37 ... rheumatologist Genotyping for polymorphisms Genomic DNA was extracted from heparin anticoagulated whole blood, after sedimentation at room temperature, using the commercial kit QIAamp® DNA blood mini kit...
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báo cáo khoa học: "A consensus linkage map for molecular markers and Quantitative Trait Loci associated with economically important traits in melon (Cucumis melo L.)" pptx
Ngày tải lên :
11/08/2014, 11:21
... provided new marker and QTL data of the NITVS mapping population and new SNP markers MO provided new marker mapping data for the ARO mapping population and GD developed the DE and DM SSR markers ... Polymorphic DNA; AFLP Amplified Fragment Length Polymorphism; indel, insertion/ deletion), the forward, reverse and extension primers (for some SNPs); and “Non-mapped markers containing the new SSR markers ... purified and recovered DNA was Sanger sequenced Proprietary programs selected sequences with SSRs and designed flanking primers Molecular markers A large proportion of molecular markers developed...
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Báo cáo y học: " Development of a new ultra sensitive real-time PCR assay (ultra sensitive RTQ-PCR) for the quantification of HBV-DNA" pot
Ngày tải lên :
12/08/2014, 04:20
... Calibration of the HBV -DNA values copies/ml vs IU/ml The calibration of the HBV -DNA values was performed against the WHO 1st International Standard for HBVDNA (OptiQuant® HBV -DNA Quantification Panel, ... International Standard for HBV -DNA (OptiQuant® HBV -DNA Quantification Panel, Accrometrix Europe B.V.) DNA was extracted and HBV -DNA was tested in replicates by using the plasmid DNA as a standard ... and quantification of HBV -DNA is essential for monitoring response to therapy and, also, for assessment of occult HBV infection Therefore, ultra-sensitive assays for HBV -DNA quantification are needed...
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Báo cáo y học: "Development and validation of molecular markers for characterization of Boehmeria nivea var. nivea and Boehmeria nivea var. tenacissima" pps
Ngày tải lên :
13/08/2014, 14:20
... on a 1.5% agarose gel for polymorphism detection Quality control A mixture of DNA was used to identify the basis of all the markers for quality control Samples contained DNA Li et al Chinese Medicine ... III and Nde I, we produced DNA fragments with predicted sizes of 0.30 kb and 0.25 kb for CAPS markers Ca-Afl0.30 and Ca-Afl-0.25, and 0.35 kb and 0.20 kb for CAPS markers Ca-Drd-0.35 and Ca-Drd-0.20 ... size of DNA standards M: DNA markers; NC: negative control G B nivea A B frutescens P rimer Sn-S62-a C B nivea Primer: Sn-S62-b G B frutescens Figure Electropherogram of SNP markers for polymorphisms...
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Báo cáo sinh học: " A note on the rationale for estimating genealogical coancestry from molecular markers" doc
Ngày tải lên :
14/08/2014, 13:21
... unlinked situation (Table 2), although the estimation improved for the small number of markers and worsened for the high number of markers For the situation with linkage, we also analyzed what happens ... better for IBD values than for genealogical coancestry, especially with a low number of markers Table Features of the regression of genealogical coancestry f on molecular coancestry (fM) and molecular ... individuals and the genetic variance of the base population Molecular coancestry If n individuals have been genotyped for one molecular marker, the molecular coancestry (or kinship), f Mij between individuals...
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A uniformly sampled genetic algorithm with gradient search for system identification
Ngày tải lên :
14/09/2015, 08:46
... A UNIFORMLY SAMPLED GENETIC ALGORITHM WITH GRADIENT SEARCH FOR SYSTEM IDENTIFICATION Zhang Zhen (B.Eng., HUST, M.Eng., WHUT ) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF ... 1.1.1 Second-Order Model For equilibrium of a dynamic system, three resisting forces resulting from the motion, i.e., the inertial force, the damping force and the spring force, counteract the external ... length Therefore the periodic requirement by discrete Fourier transform is maintained without lengthy zero padding The frequency domain substructural method originally formulated for harmonic...
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