... participation during the previous years and provided information on daily activity such as walking, stair climbing, cycling, household activities and daily commuting to and from work (walking and ... DM in obese participants and the interaction factor was of marginal significance (P=0.07) Processed meats were associated with a higher risk of type DM in overweight and obese participants (interaction ... heterocyclic amines formed during cooking Nitrosamines formed during cooking may be toxic to pancreatic cells [21] Consumption of foods with a high content of nitrites and nitrosamines has been associated...
... 5A and 5C) and iron deposition (Figures 5B and 5D) in the I+ G +St compared to the I+ G group I+ Gmiceshowsleukocytosisandsystemicelevationofinflammatoryprofilewhichcanbeattenuatedby ... with tirofibantreatment A figure demonstrating histology of other organs in I+ Gmiceand a table listing blood parameters of I+ Gmice with or without tirofiban therapy Page 14 of 15 Acknowledgements ... simvastatin therapy, butnottirofibantreatment (Figure 7) These results provide in vivo evidence that G- CSF-induced thrombosis can only be ameliorated bysimvastatin therapy, butnotbytirofiban treatment, ...
... through plain vanilla structures that involved buying all the underlying securities comprising the index as in Figure Subsequent modifications involved replicating the index by holding an optimised ... also been adopted in Asia and other emerging markets, with more than 70% of authorised investment funds in Hong Kong and Singapore now being UCITScompliant But a significant share of ETFs benchmarked ... liquid market indices Including only a subset of the underlying index securities for physical replication can lead to significant deviation in returns between the ETF and the index in volatile...
... understanding, realizing etc.), perceptive (hearing, sensing, feeling etc.), affective (loving, hating, adoring, enjoying etc.), and desiderative (wanting, desiring, wishing etc.) In this type of ... But before looking at them in some detail, it is necessary to provide a brief introduction to systemic functional linguistics 2.2 Systemic functional linguistics Systemic functional linguistics ... process of (typically human) physiological and psychological behavior, like breathing, coughing, smiling, dreaming and staring It is on the borderline between material and mental processes In this...
... opportunities and their merits and limitation Moreover, the nature of gearing and potential effected of high gearing on perceived risk and cost of capital I- Analysis of the reasons behind takeovers and ... were not involved in takeovers and large companies tended to engage in higher gearing and this led to higher retention ratio and eventually higher growth is attained (international business and ... policy during difficult trading periods It reveals the suitability of company’s capitalization (bizcovery.com) IV-Conclusion: In conclusion, following the information above, acquiring is not...
... aiming to combine the positive effects of the different single mutations on thermostability and catalytic activity Again, DNA 778 C D Fig Ribbon drawings showing the position 537 at the A C interface ... Journal compilation ê 2008 FEBS O Spadiut et al A B Stabilization of pyranose oxidase of Glu542 with a basic residue might introduce an ionic interaction exerting a greater stabilizing effect on ... oxidase homogenous (> 98%) as judged by native PAGE and SDS PAGE (Fig 3) A Kinetic characterization of mutational variants B Fig Native PAGE (A) and SDS PAGE (B) of different variants of P2Ox from...
... morphology of the fabricated Mn-doped ZnO EG is a polar solvent with a high boiling point (approximately 198°C) and a high permittivity of 37 at 20°C, which is believed to have a high dissolving capacity ... exhibits many fascinating properties [1-7] It is an intrinsic n-type II-VI semiconductor with a wide bandgap of 3.37 eV at room temperature [RT] and a large excitation binding energy of 60 meV Because ... [TC] and saturation magnetic moments [MS] is required However, until now, the mechanism involved in ferromagnetism [FM] is complicated and the reproducibility of ferromagnetic behavior is still...
... morphology of the fabricated Mn-doped ZnO EG is a polar solvent with a high boiling point (approximately 198°C) and a high permittivity of 37 at 20°C, which is believed to have a high dissolving capacity ... exhibits many fascinating properties [1-7] It is an intrinsic n-type II-VI semiconductor with a wide bandgap of 3.37 eV at room temperature [RT] and a large excitation binding energy of 60 meV Because ... [TC] and saturation magnetic moments [MS] is required However, until now, the mechanism involved in ferromagnetism [FM] is complicated and the reproducibility of ferromagnetic behavior is still...
... rised higher than before intervention, including syphilis diseas, syphilis classification, clinical signs, its complications (narrow foreskin, swelling foreskin) andtreatment regimen Proportion ... Thailand, India, Indonesia and some African countries as well as in Vietnam in Ha Noi and neighboring provinces, high rates of lower genital tract infection in high-risk populations One of the ... conceptions of LRTI: By WHO, infections of lower reproductive tract (LRTI) are infection disease caused by or notby sexual transmition disease (STD) including vulgaris, vaginalis and cervicitis...
... progression rate varies with the baseline biomarker value The association between a higher C2C/CPII ratio and faster progression was marginally significant (P = Page of (page number not for citation ... degradation of type II collagen in cartilage; C1,2C, marker for degradation of type I collagen and type II collagen in cartilage; CPII, marker for synthesis of the procollagen of type II collagen ... treatment since changes in disease activity are considerable in the first year after initiating treatment, varying significantly between patients For CTX-II and CTX -I it was found that the CTX -I values...
... biopsy samples of primary rectal tumor were evaluated by immunohistochemical staining using affinity purified mouse monoclonal antibodies against CD4 (1F6, mIgG1) and CD8 (4B11, mIgG1) (Novocastra, ... immune cells and thereby evoke anti-tumor immune responses [25,26] Since tumors with a higher number of tumor infiltrating T lymphocytes (TIL) are suggested to be originally immunogenic, it is speculated ... specificities of these mAbs in immunohistochemistry on paraffin embedded samples were confirmed with human tonsil tissue sections (data not Figure Immunohistochemical detection of CD4(+ )and CD8(+)...
... agreements on the presence of findings Sensitivities and specificities of ultrasonography, x-ray, and clinical examination, with MRI as standard reference method Sensitivities and specificities ... joint, which is often involved in OA Another contributing cause may be that the applied definitions of synovitis were too sensitive However, the definitions of MTP synovitis suggested by Koski ... rheumatological background (Figure 1) US2 was blinded to diagnosis and clinical data, and both were blinded to other imaging findings, including the sonographic findings of the other ultrasonographer...
... Westerblad, I. E Lundberg, unpublished data) The role of HMGB1 in the disease mechanisms of myositis still needs to be determined, but therapies specifically targeting anti-HMGB1 might be promising candidates ... clear evidence of significant somatic mutation, isotype switching, receptor revision, codon insertion/deletion, and oligoclonal expansion, suggesting that affinity maturation had occurred within the ... directed against histidyltRNA synthetase might drive autoantibody formation and tissue damage The association between autoantibodies directed against RNA-binding antigens and type I IFN activity,...
... traditional office visit discussions and fill important gaps in clinicians’ knowledge, significantly improving patient safety and quality of care [23] This suggests improvement in sensitivity of ... lack of standardization for assessment of these symptoms among HCV/HIV patients being considered for HCV treatment initiation In April 2008, a multidisciplinary hepatitis-HIV coinfection program ... patients with higher HIV viral loads were less likely to be treated, but these patients had recently re-initiated HIV therapy Interestingly, we did not find a significant negative impact following HCV...
... physiological defects as possible causes of stillbirth andwhich might be used as prognostic tools for identification of foetuses with low viability and high risk of stillbirth at term Materials and ... animals in this group giving birth to a normal living calf This finding again indicates that there are differences between the experimental groups in the process of parturition, and possibly the aetiology ... criteria of having a high and a low risk, respectively, for stillbirth In spite of the limited number of animals, the outcome of our selection was as expected, with the incidence of stillbirth...
... localization, intron number, and transcript details are indicated for each of the claudin genes, together with the size (in amino acids), molecular weight (in Da), and isoelectric point (Pi) of ... encoded by genes located in close proximity in the human genome are highlighted in green As previously suggested [7], claudins canbe divided in two groups in terms of sequence homology (dashed line): ... delivery and absorption One promising avenue in cancer research is the possible targeting of tumors overexpressing claudin-3 and -4 with the cytotoxic Clostridium perfringens enterotoxin, which...
... significant aspects of the SEA process These volumes are as follows (i) Integrating Strategic Environmental Assessment into Power Planning (ii) Identifying Sustainability Indicators of Strategic ... sustainability for power planning were identified, namely: (i) ecological security (pollution, land and biodiversity, rivers); (ii) climate security; (iii) food security; (iv) social security; (v) ... plan options Application of a weighting process would increase the sensitivity of this approach This volume finds that incorporating significantly greater renewable energy production and greater...
... research of nonlinear optical properties, whichshows great advantages because of its simplicity and high sensitivity [7] Using a single Gaussian laser beam in a tight focus geometry, the nonlinear ... real and imaginary parts of the nonlinearity along with its sign The sign of the non-linearity is important for practical realization of the optical devices This information cannot be obtained by ... are important parameters for designing stress-free multilayer thin film semitransparent and top-emitting organic light-emitting displays involving one or more layers of TCO films on both rigid and...
... In the next sub-‐sections the impact of settling particles, initially covering the sediment and resulting in burial of organisms, oxygen depletion and change in grain ... footprints that might be identified through monitoring relate to particles and smothering with sludge in areas with the highest sedimentation rate of cuttings -‐ Because ... sensitivity of species to changes in median grain sizes The observed range of median grain size per specie if defined as “the grain size window- of- ‐occurrence” This...