i and iv hold
Báo cáo khoa học: Correlation between functional and structural changes of reduced and oxidized trout hemoglobins I and IV at different pHs doc
... order: iron(II)HbIV > met-HbIV > met-HbI > iron(II)-HbI The larger peroxidative activity of iron(II)-HbIV with respect to metHbIV is in line with previous data obtained with human HbA derivatives [7] ... [6] Figure shows the peroxidase activity of iron(II)- and met-forms of HbI and HbIV It is evident that the enzymatic activity decreases according to the order iron(II)-HbIV > met-HbIV > met-HbI ... [3] iron(II)-HbI (Figs 1B and 2B) and iron(II)-HbIV (Figs 1A and 2A) spectra in the range 250–470 nm show similar positive bands, resembling the dichroic characteristics of other oxy-hemoglobins...
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Tài liệu Báo cáo khoa học: Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain ppt
... their implications in the metabolism of ethanol and retinoic acid In vitro and in vivo data indicate that ADH1, ADH3 and ADH4 can oxidize retinol to retinal, with ADH4 having very high efficiency ... carried out in situ hybridization studies in several species using radiolabeled short (49–51 base pairs) oligonucleotides after multiple in silico and in vitro tests for specificity Materials and methods ... significant involvement of ADH1 and ADH4 in ethanol oxidation in brain tissue Regarding retinoid metabolism in the adult brain, enzymes other than ADH4 must be active, because in vivo and in vitro...
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Báo cáo y học: "Multivariate explanatory model for sporadic carcinoma of the colon in Dukes’ stages I and IIa"
... and clinical pharmacology, and also family doctors in training o recycling periods The objectives of the investigation were explained to all participating physicians and they were provided with ... Epidemiology, 2nd edition Philadelphia: Lippincot Williams & Wilkins 1998:385-386 36 Altman DG, Andersen PK Bootstrap investigation of the stability of a Cox regression model Statistics in Medicine ... investigation to try to validate a multivariate explanatory model of the diagnosis of SCRC in Dukes’ stages I and IIa using non-conditional logistic regression and “bootstrap” analyses The original...
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Tài liệu LUYỆN ĐỌC TIẾNG ANH QUA TÁC PHẨM VĂN HỌC-Emma -Jane Austen Volume I Chapter IV docx
... poor little friend from all this hospitality and kindness, and that, if she were not taken care of, she might be required to sink herself forever With this inspiriting notion, her questions increased ... employed in his stock, and so forth; and though, with diligence and good luck, he may be rich in time, it is next to impossible that he should have realised any thing yet.’ ‘To be sure, so it is But ... books? And I have no doubt that he will thrive, and be a very rich man in time and his being illiterate and coarse need not disturb us.’ I wonder he did not remember the book’—was all Harriet’s...
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Tài liệu Interim Final Rule, Savings and Loan Holding Companies 76 Fed. Reg. 56508-56606 (Sept. 13, 2011) doc
... support As in most things, the issue is a bit more complicated than it may appear at first blush Why Are Dividends Waived? Historically, the ability to waive dividends enabled minority stock MHCs ... the interest paid on their deposits To maintain their intangible ownership interest, they must maintain their deposits If a depositor withdraws from the bank, he receives only his deposits and interest ... similar in amounts to dividends paid in fully stock institutions However, there are other practical reasons that remain today for waiving dividends to the MHC Because little or no activity is conducted...
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Tài liệu Báo cáo Y học: Interaction of decorin with CNBr peptides from collagens I and II Evidence for multiple binding sites and essential lysyl residues in collagen pot
... near to the binding site(s) and their positive charge is a stringent requisite for the binding This is not surprising, if indeed collagen binds inside the concave surface of decorin, owing to the ... decorin and collagens or their CNBr peptides is quite sensitive to the ionic strength of the buffer, suggesting an ionic character of the binding The main decorin region implicated in the binding ... collagens and positive peptides, whereas fibronectin and a 30-kDa fibronectin fragment having heparin-binding ability showed interaction with tendon decorin (Fig 4) Fibronectin is known to interact with...
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Tài liệu Báo cáo Y học: Identification of syntaxin-1A sites of phosphorylation by casein kinase I and casein kinase II ppt
... phosphorylation of synaptic vesicle-associated protein SV2 by CKI modulates its ability to interact with synaptotagmin Phosphorylation of syntaxin-1A by CKII increases its ability to interact with synaptotagmin ... that CKII phosphorylates in vitro syntaxin-1A on Ser14, and that this residue is phosphorylated in vivo, it remains to be determined whether CKII is the kinase Fig Summary of phosphorylation sites ... amino acids of syntaxin-1A while a fragment containing residues 76–265 is not phosphorylated [19] Risinger & Bennett obtained preliminary evidence that the CKII phosphorylation site is within...
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Báo cáo khoa học: Comparing the substrate specificities of cytochrome c biogenesis Systems I and II docx
... Specificity of cytochrome c biogenesis System II System I Disulfide isomerization Heme handling/ligation Fig Schematic representation of cytochrome c biogenesis Systems I and II The systems illustrated ... recognition or specificity of System II A particularly notable point for examination is the ability of Systems I and II to mature single-cysteinecontaining c-type cytochromes (XXXCH or CXXXH motifs) ... towards a diheme cytochrome c [11] In E coli, natural cytochrome c biogenesis requires at least 10 proteins, contrasting with the single protein constituting System III System II is of intermediate...
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Báo cáo khoa học: Differential interactions of decorin and decorin mutants with type I and type VI collagens pptx
... Interaction with wild-type decorin core protein (obtained by chondroitin ABC lyase digestion) in HBS Decorin core protein concentrations were as indicated (B) Interaction with wild-type decorin in ... freeze-drying avoids artificial dimerization [23]; (b) decorin binds via a binding site on the outer surface of the molecule to globular domains of collagen type VI and via a different binding site which ... decorin significantly increases the binding affinity between the two collagens (Table 4) Discussion In this study we investigated the interaction of wild-type decorin and decorin mutants with type I...
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Báo cáo khoa học: Modulation of IMPDH2, survivin, topoisomerase I and vimentin increases sensitivity to methotrexate in HT29 human colon cancer cells docx
... Benzamide riboside, tiazofurine and mycophenolic acid are potent inhibitors of this enzymic activity and phase II ⁄ III clinical trials that have been conducted with them as anticancer drugs in ... Functional validation of IMPDH2 HT29-R cells were incubated with increasing concentrations of chemical inhibitors of IMPDH activity, benzamide riboside, tiazofurin or mycophenolic acid, in the ... apoptosis protein (IAP) family [28] which directly inhibits caspase-3, -7 [29–31], and caspase-9 activities [32,33] Moreover, survivin indirectly inhibits caspase activity by promoting procaspase-3–p21...
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Báo cáo Y học: Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis pptx
... 0 Time (s) Fig BIAcore analysis of IGF-II and IGF-II analogue binding to highanity recombinant IGF1R Binding of IGF-II (A), des-(1±6)-IGF-II (B) and Arg6-IGF-II (C) to rhIGF1R measured by BIAcore ... deprivation-induced cell death (Fig 4E) and Arg6IGF-II and des(1±6)-IGF-II were essentially equipotent to IGF-II Leu27-IGF-II and des-(1±6,10)-Leu27-IGF-II did not exhibit any survival-promoting ... 100 nM (Fig 3B) The IGF-II analogues Arg6-IGF-II and des-(1±6)-IGF-II were essentially as effective as native IGF-II in preventing serum deprivation-induced apoptosis with complete protection at...
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Báo cáo khoa học: Yeast oxidative stress response Influences of cytosolic thioredoxin peroxidase I and of the mitochondrial functional state pot
... two activities Therefore, we compared cTPxI oligomeric structures in vivo under situations of normal and inhibited mitochondrial function, as it is hard to measure chaperone activity in vivo Under ... states is implicated with its chaperone ⁄ peroxidase switching [33,34], we suggest that the chaperone activity of this protein, in addition to its peroxidatic function, is probably involved with its ... genome-wide studies that did not find significant differences in the expression of antioxidant genes in cells with mitochondrial dysfunction [44,45] Participation of transcription factors in the antioxidant...
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Báo cáo khoa học: Apolipoproteins A-I and A-II are potentially important effectors of innate immunity in the teleost fish Cyprinus carpio pot
... mammalian HDL and its principal apolipoproteins A -I and A-II in antimicrobial or antiviral activities in vitro [13,14,30], these proteins have not been yet recognized as important effectors in innate ... apolipoproteins A -I and A-II in the in vitro antimicrobial activity of carp HDL Both proteins inhibit the Ó FEBS 2004 growth of Gram-positive and -negative bacteria, including fish pathogens, at micromolar ... respectively (50 lg protein per lane) Arrows indicate the migration of carp apoA -I (27.5 kDa) and A-II (12.5), respectively Table Bacteriostatic and bactericidal activities of carp apoA -I and A-II...
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Báo cáo khoa học: Silencing the expression of mitochondrial acyl-CoA thioesterase I and acyl-CoA synthetase 4 inhibits hormone-induced steroidogenesis potx
... integrity and are in line with previous reports that AA regulates the rate-limiting step in steroid biosynthesis [10] Importantly, the reduction in steroid biosynthesis was restored by addition ... signaltransduction pathways is an important issue [25] It is known that an acyl-CoA-binding protein known also as DBI (diazepam-binding inhibitor) is expressed at high concentrations in steroidogenic cells ... production in the siRNAtransfected cells is lower than the corresponding in Fig In addition, it is observed that down-regulation of MTE -I by siRNA is accompanied by a small but significant increase in...
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Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx
... percentage change in the activity of topoisomerase I In addition gyrase activity will in¯uence DNA supercoiling The sensitivities (de®ned as elasticity coef®cients by metabolic control analysis) of both ... supercoiling Certain simpli®cations were made in [25], i. e grouping of transcription and translation, assuming that transcription/translation is product insensitive and mRNA and protein degradation ... negative (i. e the activity and expression of DNA gyrase is inhibited not stimulated by higher levels of supercoiling) and those of topoisomerase I positive Consequently all four of these elasticities...
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TO HAVE AND TO HOLD pot
... XXV IN WHICH MY LORD HATH HIS DAY CHAPTER XXVI IN WHICH I AM BROUGHT TO TRIAL CHAPTER XXVII IN WHICH I FIND AN ADVOCATE CHAPTER XXVIII IN WHICH THE SPRINGTIME IS AT HAND CHAPTER XXIX IN WHICH I ... CHAPTER XXI IN WHICH A GRAVE IS DIGGED CHAPTER XXII IN WHICH I CHANGE MY NAME AND OCCUPATION CHAPTER XXIII IN WHICH WE WRITE UPON THE SAND CHAPTER XXIV IN WHICH WE CHOOSE THE LESSER OF TWO EVILS CHAPTER ... CHAPTER IX CHAPTER X CHAPTER XI CHAPTER XII IN WHICH TWO DRINK OF ONE CUP IN WHICH MASTER PORY GAINS TIME TO SOME PURPOSE IN WHICH I MEET AN ITALIAN DOCTOR IN WHICH I RECEIVE A WARNING AND REPOSE...
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The Eugenic Marriage, Volume I. (of IV.), by W. Grant Hague,-use it under the term docx
... testimonials, III, 467 Friends, choosing your, III, 367; your husband's, III, 363 Fruits, II, 273 Garbage, IV, 647 Gastric indigestion, acute, IV 527; , treatment of, IV, 527 Gastro duodenitis, IV, ... of, II, 222 Infection, direct, IV, 499 Infectious diseases, IV, 599 Inflammatory diarrhea, IV, 535 Influenza, IV, 608; symptoms of, IV, 608; treatment of, IV, 609 Injections, oil, II, 312 Insane, ... of, I, 43 Insomnia, during pregnancy, I, 86 Interior organs, complications of in syphilis, II, 146 Intermittent fever, IV, 571 Intestinal diseases of children, IV, 529 Intestinal Indigestion,...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25