... symptoms on optimal recommended medical therapy I IIaIIb III For patients with LVEF less than or equal to 35% with NYHA functional Class III or ambulatory Class IV symptoms who are receiving optimal ... Heart Association (NYHA) functional Class III or ambulatory Class IV heart failure symptoms on optimal recommended medical therapy I IIa IIb III IIb III For patients who have LVEF less than or ... reasonable *All primary SCD prevention ICD recommendations apply only to patients who are receiving optimal medical therapy and have reasonable expectation of survival with good functional capacity...
... (Roche Diagnostics GmbH, Mannheim, Germany) at the time of each StO2 measurement Laboratory analysis Blood was drawn from the pulmonary artery at the time of each StO2 measurement in order to determine ... -0.091, P = 0.60; Figure 1) In group A StO2 slightly overestimated SvO2 (bias -2.3%, precision 4.6%; Figure 2) In group B StO2 overestimated SvO2, but important disagreement between these variables ... StO2 does not estimate SvO2 in patients with severe left heart failure and additional severe sepsis or septic shock • StO2 values could be used to provide rapid, noninvasive estimation of SvO2;...
... Switzerland) at the time of each StO2 measurement Laboratory analysis Blood was withdrawn from the superior vena cava approximately cm above the right atrium and from the pulmonary artery at the time of ... sepsis/septic shock), estimate the SvO2 by using basal StO2 In the case of a prolonged skeletal muscle StO2 deoxygenation rate, look for additional sepsis, and the deoxygenation rate can estimate discrepancy ... Severity of disease Sepsis-related Organ Failure Assessment (SOFA) score was calculated at the time of each measurement to assess the level of organ dysfunction [16] Dobutamine and norepinephrine...
... paired t-test P values < 0.05 were considered significant Power estimate for TnI was 90% to detect a mean difference between time-points as small as 0.02 ng/ml (using experimentally determined ... from the OPTIME-CHF study J Am Coll Cardiol 2003, 41:997-1003 Matsumori A, Shioi T, Yamada T, Matsui S, Sasayama S: Vesnarinone, a new inotropic agent, inhibits cytokine production by stimulated ... especially important factor since patients with ischemic disease seemed to be at greater risk in the OPTIME study [15] The marked improvements seen in inflammatory and apoptotic markers were somewhat...
... of healthcare resources [1-6] Population-based studies conducted in Australia and Europe have estimated the annual incidence of sARF at 4.2 to 13.4 per 100,000 population; however, these studies ... new requirement for RRT with evidence of renal dysfunction (serum creatinine ≥ 150 µmol/l) at the time of or during ICU admission [8,9] Those patients that received RRT for any indication in the ... co-morbidities was assessed using the Charlson Co-morbidity Index [25] Shock preceding or at the time of initiation of An understanding of the epidemiology of sARF is important to establish its...
... test was used for multiple comparisons The aims of our study were: to analyse the filter survival time (FST) during DrotAA infusion – in the presence or absence of additional anticoagulation compared ... data, details of anticoagulation and RRT – including filter pressure parameters – and quantity and timing of blood products transfused were obtained by searching the departmental electronic patient ... of international normalized ratio (INR) (p = 0.047) and in the activated partial thromboplastin time (APTT) (p < 0.0001) Multivariate logistic regression analysis of the factors associated with...
... are recorded in a pre-hospital patient chart that includes core times (activation time, time of arrival, time of departure and time patient care is ended), vital parameters, patient data, applied ... no significant difference in patient age, sex, NACA score, RTS or GCS Further, mean time to scene and scene time were significantly shorter in RRV missions compared to helicopter missions: ± vs ... GCS: Glasgow coma score, RTS: revised trauma score (22 vs 15%, p = 0.003) The mean scene time and transport time were significantly longer in patients with prehospital ETI compared to ETI in the...
... in Table Values are adjusted for sex, age, smoking status and time of assessment (admission or discharge) Interaction terms between time of assessment and disease stage were tested but were not ... was observed Also, although the time frame for assessing the questionnaire was within days of admittance in both studies, there may have been differences in average time In our study, about 30% ... Especially in the SF-12, this probably resulted in an overestimation of HrQoL, whereas the proportion with worst health state may be underestimated Sensitivity to change might also be affected, if...
... 146.0 -6.3 - 123.0 aTime point is the time point at which infliximab treatment was discontinued; time point is that when retreatment began *P < 0.05, **P < 0.001, when means at time points and are ... response was almost months Since the time of persistent clinical efficacy of infliximab after discontinuation varied widely between patients, the optimal dose and the optimal infusion interval for infliximab ... patients; 23.8%) and week 24 (37/42 patients; 88.1%) The mean time between TP and TP was 17.5 weeks (± 7.9 weeks, range to 45) and the median time was 15 weeks Means and changes of the assessed parameters...
... time on active therapy, and time after discontinuation of therapy (time off therapy) The number of events per year of followup was calculated for each RA patient for total time of followup, time ... Their baseline characteristics are shown in Table The median follow-up time was 2.3 years (range 0.02 to 9.6) The total follow-up time was 911 patient-years, with 627 patient-years representing active ... consisted mostly of topical application of corticosteroids and sometimes of systemic antihistamines Benign tumors were recorded seven times during TNF-αblocking therapy One patient experienced an...
... left main or two or three major epicardial vessel disease In the case of disagreement with the estimation of the aortic regurgitation between echocardiographic and angiographic assessment, angiographic ... Carbomedicis If indicated, concomitant coronary artery bypass surgery was performed at the same time as AVR, using standard Catovic et al Journal of Cardiothoracic Surgery 2011, 6:51 http://www.cardiothoracicsurgery.org/content/6/1/51 ... patient lost to follow-up) Two patients died during the first postoperative year, and the data for time and cause of death were reviewed from the relevant medical documentation, supplied by patient’s...
... while the reduction in depression/ anxiety was stronger (β = -0.09 95% CI = -0.12; -0.04 p < 0.001) In the GAF analyses, the linear gradient was stronger after including years 1-5 only (β = 1.03 ... Statistical analysis All analyses were performed using Stata 11 [22] As patients were interviewed several times, yielding more than one observation per person (i.e several records in the dataset), the assumption ... obtained from multilevel linear regression analyses can be interpreted in the same way as the estimates obtained from standard unilevel analyses The two GAF scales and the four BPRS dimensions...
... the physical activity level of each patient, and daily energy requirements of each patient were estimated The intervention program consisted primarily of dietary counseling, physical activity counseling ... counseling, subjects were instructed to participate in light or moderate exercise at least 30 3-5 times per week Biochemical measurements Biochemical measurements were undertaken at the beginning ... carried out for associations between body weight change and body fat percentage (BF %) change over time (baseline to mo, mo and mo) Statistical significance was taken as P < 0.05 The statistical...
... results in the same manner as those in Tugrul et al.’s paper [1], we could conclude that it is sometimes possible to present the data in such a way resulting in delusive conclusions Analyzing the...
... for each time point appears below the x-axis for (᭹) survivors and (᭺) nonsurvivors *P < 0.05 versus nonsurvivors APTT, activated partial thromboplastin time; PT, prothrombin time Figure Time courses ... placebo infusion Prothrombin time (PT), activated partial thromboplastin time (APTT), and D-dimer, protein C, protein S, and antithrombin levels were obtained at each time point Platelet counts ... Means with 95% confidence intervals were plotted over time If analysis of variance tests indicated significance overall, then tests at each time point were performed to determine when significant...
... management of FNAB-proven infected necrosis Importantly, there was no consensus regarding the optimal timing of surgery Chiang and coworkers [3] compared management of patients with SAP between two ... develop a multivariate model using new strategies involving neuronal networks Interestingly, their optimal prediction model (logistic approach) identified four variables: age, greatest serum creatinine ... primarily to permit early prediction of hospital mortality and not to classify the severity of SAP over time, and so infection status was not included in the analysis Current trends in treatment for severe...
... considered over time [38] However, historical methods of estimating EVLW have been complex, clinically difficult, and poorly reproducible [36,43-46] The most common method of estimating EVLW continues ... indicate standard errors *Significant between-group differences at the marked time points; P < 0.001 for EVLW differences over time, by analysis of variance for ARDS patients with low EVLW patients ... ITTV (ml) = CO × mean transit time of the thermal indicator [22,23] The pulmonary thermal volume (PTV) is given by PTV (ml) = CO × τ, where τ is exponential decay time of the thermodilution curve...