... environmental health disparities and improving the health of all children.
The ultimate goal of the Children’s Environmental HealthandDisease Prevention Research
Centers is to create a healthy and sustainable ... Environmental Health
Risks and Safety Risks, which
directs federal agencies to identify
and assess environmental risks
to children’s health.
1998: Eight Children’s Centers are
est
ablished by NIEHS and ... is to reduce
children’s health risks, protect children from environmental
threats and promote their healthand well-being in the
communities where they live, learn and play.
Background
For...
... levels.
TEC kinases anddisease A. Hussain et al.
2002 FEBS Journal 278 (2011) 2001–2010 ª 2011 The Authors Journal compilation ª 2011 FEBS
MINIREVIEW
TEC family kinases in healthanddisease – loss-of-function
of ... ITK–SYK fusion oncogene induces
a T-cell lymphoproliferative disease in mice mimicking
human disease. Cancer Res 70, 6193–6204.
TEC kinases anddisease A. Hussain et al.
2010 FEBS Journal 278 (2011) ... individuals
with mild disease, thereby providing the missing data.
The phenotype of XLA and the
potential of BTK and ITK inhibitors
The outcome of defective BTK signaling in humans
has been described...
... SHIKE
Section E. Prevention and Management of Skeletal and Joint Disorders
Chapter 83. Bone Biology in Healthand Disease
ROBERT P. HEANEY
Chapter 84. Nutrition and Diet in Rheumatic Diseases
CLAUDIO GALPERIN, ... Respiratory Function, and Disease
MARGARET M. JOHNSON, ROBERT CHIN, JR., AND EDWARD F. HAPONIK
Chapter 91. Nutrition and Retinal Degenerations
ELIOT L. BERSON
Chapter 92. Diagnosis and Management of ... Ph.D.
Director and Research Nutritionist
Grand Forks Human Nutrition Research Center
United States Department of Agriculture
Grand Forks, North Dakota
MAN S. OH, M.D.
Professor of Medicine
Health Sciences...
... management and communication components, a number of international regulatory and
standard-setting bodies have introduced uniform standards. These include standards for human- health
and environmental-safety ... impacts — both positive and negative — on humanhealthand the environment.
1.4 Recent international controversies and study initiative
Conflicting assessments and incomplete substantiation ... productivity, or improved quality
and nutritional and processing characteristics, which can contribute directly to enhancing human
health and development. From a health perspective, there may also...
... evolution:
selection, drift, mutation and migration. Evolution’s role is central in the sub-discipline of
biology that addresses healthanddisease in humans and training in evolutionary thinking ... very
complex manner, therefore the understanding of the diseases that affect human beings has
been equally complicated, and thus the treatment of many diseases has had to be very
aggressive; ... invading bacteria and which now are called
mitochondria, and which I refer to as biological competition [2], could explain the great
majority of human diseases, which are more than diseases, they...
... metalloproteinase activity in health
and disease
Elin Hadler-Olsen, Bodil Fadnes, Ingebrigt Sylte, Lars Uhlin-Hansen and Jan-Olof Winberg
Department of Medical Biology, Faculty of Health Sciences, University ... metalloproteinase 2 from human rheumatoid
synovial fibroblasts. Purification and activation of the
precursor and enzymic properties. Eur J Biochem 194,
721–730.
20 Das S, Mandal M, Mandal A, Chakraborti ... various
human MMPs [3]. The various domains, modules and
motifs in the MMPs are involved in interactions with
other molecules, and hence affect or determine the activ-
ity, substrate specificity, and...
... novel antagonistic ligand of the Met
receptor. J Cell Biol 185, 743–754.
54 Theocharis AD, Skandalis SS, Tzanakakis GN &
Karamanos NK (2010) Proteoglycans in health and
disease: novel roles ... involved in many aspects
of mammalian biology, both in healthand disease. They are now being rec-
ognized as key signaling molecules with an expanding repertoire of molecu-
lar interactions affecting ... during
quiescence [20,21]. Indeed, both the mouse and
human decorin structural organization of their gene
and promoter are quite complex [22–24] and subject
to an intricate transcriptional regulation...
... processes and are key to normal matrix
turnover, but also have essential roles in development
and reproduction, and in pathological tissue remodel-
ling during inflammatory disease, cancer invasion and
metastasis. ... tissues
and some musculoskeletal tissue. Here, our under-
standing of syndecan shedding and its function in
wound healing and tumour progression is reviewed.
Other reviews on syndecan structure and ... Syndecans-1 and -3 core proteins are larger than those of syndecan-2 and -4, and can
bear both heparan and chondroitin sulfate chains. The GAG chains are substituted on core protein serine residues and...
... signaling function, and elucidation of
heparanase route and function in the cell nucleus, will
advance the field of heparanase research and reveal its
significance in healthand disease. Resolving ... in healthand disease: new concepts for
heparanase function in tumor progression and metastasis
Uri Barash
1
, Victoria Cohen-Kaplan
1
, Ilana Dowek
2
, Ralph D. Sanderson
3
, Neta Ilan
1
and
Israel ... 388–392.
92 Theocharis AD, Skandalis SS, Tzanakakis GN &
Karamanos NK (2010) Proteoglycans in health and
adisease: novel roles for proteoglycan in malignancy
and their pharmacological targeting....
... programmes and better diagnosis and control of avian
diseases. Of all these core elements, poultry healthanddisease
can be the least predictable.
Although poultry diseases from nutritional and metabolic ... Respiratory and kidney disease, egg production drops +
Infectious larnygotracheitis Virus Respiratory disease (varying severities) and conjunctivitis +
Newcastle disease Virus # Respiratory and nervous ...
Poultry disease Agent Main signs and lesions produced in diseases in the field Major route of spread
Faeco-oral
(and contact)
Aerosols
(and contact)
Eggs
Avian mycoplasmosis Bacterium Respiratory disease, ...
... NATIONAL INSTITUTE OF ENVIRONMENTAL1
HEALTH SCIENCES; AWARDS FOR DEVELOP-2
MENT AND OPERATION OF MULTIDISCI-3
PLINARY RESEARCH CENTERS REGARDING4
WOMEN’S HEALTHANDDISEASE PREVEN-5
TION.6
Subpart ... the Public Health7
Service Act (42 U.S.C. 285
L
et seq.) is amended by adding8
at the end the following section:9
‘‘
MULTIDISCIPLINARY RESEARCH CENTERS REGARDING
10
WOMEN
’
S HEALTHANDDISEASE ... Director of19
the Office of Research on Women’s Healthand with the20
advisory council for the Institute.21
‘‘(b) R
ESEARCH
, T
RAINING
,
AND
I
NFORMATION AND
22
E
DUCATION
.—23
‘‘(1) I
N GENERAL
.—Each...
... a
high degree the health of the child.
PLAN TO BE PURSUED WITH THE VIGOROUS AND HEALTHY A child of a vigorous constitution
and robust health, as he rises from his bed refreshed and active by his ... child
had quiet and refreshing sleep, and in twelve hours a healthy motion was passed. The child gained flesh
almost as quickly as it had previously lost it, and is now as fine and healthy an infant ... herself to the duties of a nurse, and
give up all engagements that would interfere with her health, and so with the formation of healthy milk, and
with the regular and stated periods of nursing her...