hormone parathyroid hormone related protein receptor
Báo cáo y học: " Expression of parathyroid hormone-related protein during immortalization of human peripheral blood mononuclear cells by HTLV-1: Implications for transformation" pps
... interleukin-1 and parathyroid hormonerelated protein production on adult T-cell leukemia cells in vitro Blood 1995, 86:2257-2267 Dunbar ME, Wysolmerski JJ, Broadus AE: Parathyroid hormonerelated protein: ... Calviello G, Lanza P, Giangaspero F, Silvestrini A, et al.: Human parathyroid hormone- related protein and human parathyroid hormone receptor type are expressed in human medulloblastomas and regulate ... factors such as interleukin-1, tumor necrosis factor β, parathyroid hormone- related protein (PTHrP), macrophage inflammatory protein- 1α (MIP-1α) and receptor activator of nuclear factor-κB ligand (RANKL)...
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Báo cáo Y học: Effect of coenzymes and thyroid hormones on the dual activities of Xenopus cytosolic thyroid-hormone-binding protein (xCTBP) with aldehyde dehydrogenase activity potx
... thyroid -hormone- binding protein (CTBP) in Xenopus liver Eur J Biochem 225, 1105–1112 10 Yamauchi, K., Nakajima, J., Hayashi, H., Horiuchi, R & Tata, J.R (1999) Xenopus cytosolic thyroid hormone- binding ... carcinomas as a flavopiridol-binding protein FEBS Lett 454, 100–104 22 Yamauchi, K & Tata, J.R (2001) Characterization of Xenopus cytosolic thyroid -hormone- binding protein (xCTBP) with aldehyde dehydrogenase ... quantitation of microgram quantities of protein utilizing the principle of protein- dye binding Anal Biochem 72, 248–254 24 Scatchard, G (1949) The attractions of proteins for small molecules and ions...
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Báo cáo y học: "Autoantibodies to low-density-lipoprotein-receptor-related protein 2 (LRP2) in systemic autoimmune diseases" pps
... lipoprotein receptor -related protein in systemic autoimmune diseases J Immunol 2001, 166:1360-1369 Hussain MM: Structural, biochemical and signaling properties of the low-density lipoprotein receptor ... hybrid protein with maltose-binding protein (MBP) Recombinant CD69 as an MBP fusion protein was similarly prepared, as we described earlier [6] Purification of the recombinant fusion proteins ... and R175 Arthritis Research & Therapy Vol No Ooka et al Figure Map of low-density-lipoprotein -receptor -related protein (LRP2) Six gene fragments that, with overlaps, covered approximately one-third...
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Báo cáo y học: "A prospective study of androgen levels, hormone-related genes and risk of rheumatoid arthritis" pptx
... number of hormone receptor genes involved in androgen– Page of 12 (page number not for citation purposes) estrogen pathways for association with RA The estrogen receptor, the androgen receptor ... progesterone receptor are members of the nuclear receptor superfamily, which depend on ligand binding for activation The androgen receptor gene (AR) located on chromosome X encodes the androgen receptor, ... between plasma hormone levels for total testosterone, free testosterone, and DHEAS, as well as genetic polymorphisms in the androgen receptor (AR), estrogen receptor (ESR2), progesterone receptor (PGR),...
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Functional role of low density lipoprotein receptor related protein 5 and 6 in alzheimers disease
... in part through its receptors 14 ApoE receptors include the core members from LDL receptor family such as low density lipoprotein (LDL) receptor -related protein (LRP) 1, apoE receptor (apoER2) ... distantly related members like sorting proteinrelated receptor/ lipoprotein receptor 11 (SorLA/LR11), LRP5 and LRP6 [108,109] LDL receptor family members are a group of single transmembrane proteins ... mitochondrial dynamics in AD 13 1.4 ApoE receptors 14 1.4.1 Low density lipoprotein receptor family 14 1.4.2 Low density lipoprotein -related protein and 16 1.4.3 Dysregulated...
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Tài liệu Báo cáo khoa học: Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT–MIM interaction pptx
... (Fig 1A) Several MIT domain-containing proteins have been shown to bind endosomal sorting complex required for transport (ESCRT)-III proteins and their related proteins [21–23] Fig Schematic representations ... previously reported that calpain associates with a subset of ESCRT-III and its related proteins: charged multivesicular body protein (CHMP)1A CHMP1B, CHMP2A, CHMP4b, CHMP4c and CHMP7 [28] We also showed ... incubation, unbound proteins were removed (Unbound), and the beads were washed Proteins bound to the beads were eluted with a buffer containing mM D-desthiobiotin (Purified proteins) Samples were...
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Tài liệu Báo cáo khoa học: A novel tachykinin-related peptide receptor of Octopus vulgaris – evolutionary aspects of invertebrate tachykinin and tachykinin-related peptide ppt
... Octopus tachykinin -related peptide receptor A Kanda et al protein upon binding to TK peptides [5,6] In the ascidian Ciona intestinalis, ... of G protein coupling and receptor function were located exclusively in the third intracellular loop and the C-terminus, suggesting that phosphorylation is involved in the modulation of G protein ... anticipated to be correlated with molecular and functional evolution of neuropeptides and hormones; for instance, two oxytocin ⁄ vasopressin superfamily peptides and their three receptors were characterized...
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Tài liệu Báo cáo khoa học: Identification of membrane-bound serine proteinase matriptase as processing enzyme of insulin-like growth factor binding protein-related protein-1 (IGFBP-rP1/angiomodulin/mac25) doc
... Various extracellular proteinases regulate cellular functions by degrading or processing protein substrates including extracellular matrix proteins, growth factors and cell surface proteins For example, ... level of proteinase(s) responsible for the processing of IGFBP-rP1 To determine the class of the IGFBP-rP1-cleaving proteinase, OVISE cells were cultured in the presence of various proteinase ... cleaved form of IGFBP-rP1 (25 kDa), whereas a cysteine proteinase inhibitor (leupeptin), an aspartic proteinase inhibitor (pepstatin) and a metalloproteinase inhibitor (N-(R)(2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-l3-(2¢-naphthyl)alaninyl-l-alanine...
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Tài liệu Báo cáo khoa học: A novel tachykinin-related peptide receptor docx
... tachykinin receptors and tachykinin -related peptide receptors Consequently, we concluded that this GPCR is a putative Urechis tachykinin -related peptide receptor and designated the receptor as ... tachykinin -related peptide receptors Some tachykinin -related peptides occasionally showed different activities on tachykinin -related peptide receptors For example, the locust tachykinin -related ... tachykinin -related peptides and their receptors from different species have so far been employed for studies of tachykinin -related peptide activity on insect tachykinin -related peptide receptors...
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Báo cáo khoa học: Purification and structural analysis of the novel glycoprotein allergen Cyn d 24, a pathogenesis-related protein PR-1, from Bermuda grass pollen pot
... newly identified allergen is a pathogenesis -related protein (PR-1) A newly identified pollen allergen as pathogenesis -related proteins peak to contain a protein with an apparent molecular mass of ... [5] Our preliminary study showed that peptides of the 21 kDa protein had sequence similarity to pathogenesis -related proteins These proteins are induced by stresses such as fungal and bacterial ... indicated that BGP contains about 230 proteins including isoforms ⁄ degraded protein products and around 65 of these are IgE-binding proteins [19] Only a few of these proteins have been A newly identified...
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Báo cáo khoa học: Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein potx
... The transthyretin -related proteins (TRPs) comprise a family of proteins recently shown to function as 5-hydroxyisourate hydrolases in the purine degradation pathway [19–23] These proteins are also ... Thermostability and protein structures We have analyzed the structures of hTTR (Protein Data Bank code: 1F41 [12]), sbTTR (Protein Data Bank code: 1SN2, [16]) and ecTRP (Protein Data Bank code: ... transthyretin -related protein family Eur J Biochem 270, 518–532 20 Lee Y, Lee DH, Kho CW, Lee AY, Jang M, Cho S, Lee CH, Lee JS, Myung PK, Park BC et al (2005) Transthyretin -related proteins function...
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Báo cáo khoa học: Role of the structural domains in the functional properties of pancreatic lipase-related protein 2 pot
... PLRP2 are now available in the Protein Data Bank: rat PLRP2 (Protein Data Bank code 1BU8 [31], human PLRP2 (Protein Data Bank code 2OXE, to be published), and hoPLRP2 (Protein Data Bank code 1W52 ... lipase -related protein type I: a specialized lipase or an inactive enzyme Protein Eng 11, 135–142 15 De Caro J, Carriere F, Barboni P, Giller T, Verger R & De Caro A (1998) Pancreatic lipase -related ... lipase -related protein is a galactolipase Biochemistry 43, 10138–10148 21 Reboul E, Berton A, Moussa M, Kreuzer C, Crenon I & Borel P (2006) Pancreatic lipase and pancreatic lipase -related protein...
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Báo cáo khoa học: The transthyretin-related protein family doc
... Ó FEBS 2003 Analysis of transthyretin -related protein (Eur J Biochem 270) 519 Table Sequences from TTR related proteins The sequences comprise putative protein sequences from SwissProt/TrEBMLSP ... transthyretin -related protein (Eur J Biochem 270) 527 Fig Purification of E coli TRP (A) Size exclusion chromatography The purified protein migrates as a single peak showing a tetrameric protein of ... the TTR -related protein from the Gram-negative bacterium E coli The construct including the signal sequence generates two protein products and MS confirms that one corresponds to the mature protein...
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Báo cáo khoa học: Fragile X-related protein FXR1 controls posttranscriptional suppression of lipopolysaccharide-induced tumour necrosis factor-a production by transforming growth factor-b1 doc
... mental retardation -related protein (FXR1) [16–22] FXR1 is a homologue of the Fragile X mental retardation syndrome protein, and, together with Fragile X mental retardation -related protein 2P, forms ... TGF-b1 leads to post-transcriptional downregulation of TNF-a protein Many RNA-binding proteins, such as TTP, TIA-1, HuA, TIA-1 -related protein, and FXR1, are known to bind to the ARE in the 3¢-UTR ... retardation -related family of RNA-binding proteins [23] Targeted deletion of FXR1 produced a mouse that died soon after birth, but macrophage cell lines generated from these animals had enhanced TNF-a protein...
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Báo cáo y học: "Tumor necrosis factor α-induced adipose-related protein expression in experimental arthritis and in rheumatoid arthritis" pptx
... investigated TNFα -related molecules by GeneChip analysis The expression of TNFα-induced adipose -related protein (TIARP) was the highest in GeneChip study TIARP was identified as a transmembrane protein ... RIPK, receptor (tumor necrosis factor receptor superfamily)-interacting serine-threonine kinase and 2; TNFAIP, tumor necrosis factor alpha-induced protein; TNFR, tumor necrosis factor receptor; ... superfamily; TRAF, tumor necrosis factor receptor- associated factor; TTRAP, tumor necrosis factor receptor- associated factor and tumor necrosis factor receptor- associated protein National Center for Biotechnology...
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Báo cáo y học: " Effect of HIV-1-related protein expression on cardiac and skeletal muscles from transgenic rats" docx
... studies confirm that HIV-1 -related proteins have significant biological activity and induce systemic muscle atrophy We next identified the effect of HIV-1 -related protein expression on oxidative ... derangements suggesting a predominant role of oxidative stress in HIV-1 -related cardiomyopathies [8] However, the influence of HIV-1 -related protein- induced oxidative stress on specific redox-sensitive ... non-replicative, non-infectious HIV-1 transgenic rat model [14], we show that chronic expression of HIV-1 -related proteins causes significant cardiac and skeletal muscle morphological derangements including...
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Báo cáo y học: " Inhibition of HIV-1 replication by small interfering RNAs directed against Glioma Pathogenesis Related Protein (GliPR) expression" potx
... Murphy EV, Zhang Y, Zhu W, Biggs J: The human glioma pathogenesisrelated protein is structurally related to plant pathogenesis -related proteins and its gene is expressed specifically in brain tumors ... structural similarities with its homologous plant PR-1 proteins, mammalian testis proteins (TPX1) and the insect venom Ag-5 protein, which are secretory proteins [29,30], it has been suspected that GliPR ... proteoglycans and membrane proteins involved in cellular proliferation, migration and matrix interactions Syndecan-1 functions as receptor for internalizing extracellular Tat protein [42] and syndecan-2...
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The investigation of transcription related protein protein interactions of histones in saccharomyces cerevisiae
... of protein- protein interactions occurring anywhere inside the cell and is suitable to screen transactive baits Ubiquitin is a small protein important for the turnover of cellular proteins Proteins ... to produce both protein- protein and protein- DNA crosslinks, the protein to be analyzed not necessarily have to bind to DNA directly, but can be crosslinked to 27 DNA via other proteins such as ... result from the binding of test protein to a common ligand – another protein or a larger structure It is necessary to use more than one method to validate a protein- protein interaction identified...
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Roles of TACC related protein, mia1p in MTOCs and microtubule dynamics in schizosaccharomyces pombe 1
... Mto2p 12 1.2.3 Organizing microtubule bundles 13 1.2.3.1 Minus-end-directed motor protein Klp2p 14 1.2.3.2 Bundling protein Ase1p 14 1.2.3.3 Model of maintaining ordered microtubules 15 1.2.4 Arrangement ... microtubule cytoskeleton 23 1.2.5 Self-organization of fission yeast microtubules 1.3 Mia1p as a TACC -related protein 26 27 1.3.1 TACCs in human 27 1.3.2 TACC in Drosophila 28 1.3.3 Current knowledge about ... nuclear envelope 44 3.1.1 Lack of microtubule binding protein Mia1p results in fewer interphase Microtubules 44 3.1.1.1 Mia1p is a microtubule binding protein 44 3.1.1.2 mia1Δ cells exhibit disordered...
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Roles of TACC related protein, mia1p in MTOCs and microtubule dynamics in schizosaccharomyces pombe 2
... novel family of centrosomal proteins, the transforming acidic coiled-coil -related (TACC) proteins, has been identified in a wide variety of organisms These closely related proteins are enriched in ... microtubule dynamics found that at least two proteins are involved in this process One of them is the minus-end-directed protein Klp2p 1.2.3.1 Minus-end-directed motor protein Klp2p Klp2p is a kinesin of ... 1999a; Still et al., 1999b) How can TACC proteins function as both transforming and tumor-suppressing protein? What are 27 the normal functions of TACC proteins? A clue to this question came with...
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